This source explores the impact of semaglutide, a weight loss medication, on muscle mass, glucose regulation, and bone health in adults with obesity. It highlights that muscle loss is a common consequence of weight reduction, particularly with semaglutide, and this loss can negatively affect glucose homeostasis and bone mineral density. The study indicates that older age and female sex may increase the risk of muscle loss while higher protein intake might offer protection. Furthermore, significant muscle loss was linked to less improvement in glucose control among semaglutide users, suggesting the importance of preserving muscle mass during treatment to enhance metabolic outcomes.
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