GLP‐1 medication and weight loss: Barriers and motivators among 1659 participants managed in a virtual setting

Abstract Aims Glucagon-like peptide-1 (GLP-1) receptor agonists, alongside dual receptor agonists targeting glucose-dependent insulinotropic polypeptide (GIP) receptors, represent transformative therapies for obesity management. Despite their increasing use, patient perspectives of these treatments remain underexplored. This exploratory study aimed to examine the experiences and attitudes of individuals using GLP-1 medications (GLP-1s) for weight loss, focusing on … Read more

Diabetes drugs GLP-1RA and SGLT2i lower dementia risk in older adults, study finds

A large population-based study found that GLP-1 receptor agonists (GLP-1RAs) and SGLT2 inhibitors (SGLT2is), two classes of glucose-lowering drugs used in type 2 diabetes, were associated with a significantly reduced risk of Alzheimer’s disease and related dementias (ADRD). These findings suggest potential neuroprotective benefits and highlight drug repurposing as a promising strategy for ADRD prevention.

Coya Therapeutics Announces Publication of GLP-1/LD IL-2 Combination Biologic (COYA 303) Demonstrating Synergistic Enhancement of Regulatory T Cell Function and Protection Against Treg Apoptosis (Cell Death)

HOUSTON–(BUSINESS WIRE)–Coya Therapeutics, Inc. (NASDAQ: COYA) (“Coya” or the “Company”), a clinical-stage biotechnology company developing biologics intended to enhance regulatory T cell (Treg) function, today announced publication of the results of a study designed to evaluate the effects of COYA 303 (LD IL-2 and GLP-1RA), Coya’s investigational biologic combination to suppress pro-inflammatory myeloid cells, enhance … Read more

Inside a neuroscientist’s quest to cure coma

The study of consciousness is a field crowded with scientists, philosophers, and gurus. But neuroscientist Daniel Toker is focused on its shadow twin: unconsciousness. His path to this research began with a tragedy — one he witnessed firsthand. While at a music festival, a young concertgoer near Toker dove headfirst into a shallow lake. He … Read more