Month: April 2025

(MedPage Today) — A Maryland man with diabetes is suing Novo Nordisk, alleging that semaglutide (Ozempic, Wegovy) made him blind due to nonarteritic anterior ischemic optic neuropathy. (NBC News) In a large study of diabetes, heart failure, or…

Recent anecdotal reports have highlighted strange side effects of GLP-1 medications used for weight loss like “Ozempic mouth” and “Ozempic feet.” Elena Popova/Getty Images “Ozempic feet” and “Ozempic mouth” are the latest reported cosmetic side effects from GLP-1 medications used for weight loss. Experts say wrinkles and sagging skin can result from rapid weight loss … Read more

Novo Nordisk to sell Wegovy through telehealth firms to cash-paying US customers  Reuters Novo Nordisk opens weight loss drug Wegovy to telehealth; Hims & Hers shares rocket 18%  CNBC Hims & Hers stock jumps on Novo Nordisk GLP-1 partnership  Yahoo Finance LifeMD Announces Plans to Expand Affordable Access to Wegovy® for Cash-Pay Patients  GlobeNewswire Novo Nordisk strikes telehealth deals … Read more

Drugs that bind to and activate the receptors for the hormones GLP-1 and GIP are effective in the treatment of obesity and diabetes. Surprisingly, active substances are currently being developed that not only activate the GIP receptor (agonists) but also block it (antagonists). They also have a positive effect on body weight.

voronaman/Shutterstock More than 2.5 billion adults worldwide are currently overweight or obese, according to estimates from the World Health Organization. This staggering number highlights a growing global health crisis. Obesity isn’t just about weight – it’s a powerful risk factor for a range of serious diseases, including type 2 diabetes, kidney disease, heart attacks, and … Read more

Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning, we’ve got a bunch of news this morning about GLP-1 drugs,  compounding, and biotechs’ interactions with the FDA. Let’s get into it. Read the rest…

Humana’s CenterWell will begin filling and shipping orders for the GLP-1 weight loss drug Wegovy that are prescribed through Hims & Hers Health, LifeMD and Ro.

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Nature Metabolism, Published online: 29 April 2025; doi:10.1038/s42255-025-01294-x This study, together with a companion manuscript, show that, in mice, weight loss as a result of GIP receptor antagonism requires, and potentiates, functional GLP-1 receptor signalling in the brain, explaining how both GIP receptor agonists and antagonists trigger weight loss through different mechanisms.