Mayo Clinic Study: Genetic Test Can Predict GLP-1 Nausea Side Effects

What You Should Know:  – A new study from Mayo Clinic, released this past weekend, signals a significant advancement in understanding and potentially mitigating the challenging side effects associated with popular GLP-1 agonist medications like Wegovy and Zepbound.  – Led by Mayo Clinic physician and obesity expert Andres Acosta, MD, PhD, the research reveals that … Read more

Journal Article – GIPR Antagonism and GLP-1R Agonism Metabolic Effects

Gutgesell RM, Khalil A, Liskiewicz A, Maity-Kumar G, Novikoff A, Grandl G, Liskiewicz D, Coupland C, Karaoglu E, Akindehin S, Castelino R, Curion F, Liu X, Garcia-Caceres C, Cebrian-Serrano A, Douros JD, Knerr PJ, Finan B, DiMarchi RD, Sloop KW, Samms RJ, Theis FJ, Tschöp MH, Müller TD. GIPR agonism and antagonism decrease body weight … Read more

How just a fishing expedition helped lead to GLP-1

Professor of Medicine Joel Habener. Veasey Conway/Harvard Staff Photographer Health How just a fishing expedition helped lead to GLP-1 Story of game-changing therapy illustrates crucial role of fundamental research breakthroughs Jacob Sweet Harvard Staff Writer May 8, 2025 4 min read Part of the Profiles of Progress series Sometimes an important discovery springs from a … Read more

OM1 to Present Groundbreaking Research on GLP-1 Agonists and Suicidal Ideation at ISPOR 2025

BOSTON–(BUSINESS WIRE)–OM1: What: OM1, the leader in real-world data and AI-driven insights in mental health for life sciences, announced an upcoming poster presentation hosted by Jessica Probst, OM1’s Principal, Real World Evidence. The poster focuses on the linkage between Glucagon-like Peptide 1 Receptor Agonists (GLP-1s) and Suicidal Ideation (SI). Consistent with other findings and despite … Read more

TNF Pharmaceuticals and Renova Health Report Positive Results in Identifying Targets for Treating TNF-Driven Inflammation in Patients Receiving GLP-1 Agonists

BALTIMORE–(BUSINESS WIRE)—- $TNFA–TNF Pharmaceuticals, Inc. (Nasdaq: TNFA) (“TNF” or the “Company”), a clinical stage biopharmaceutical company committed to developing novel therapies for autoimmune and inflammatory conditions, and Renova Health, a company committed to focusing on outpatient care to minimize costs, impact and the need for hospitalization, today announced positive results from the first stage of … Read more

More adolescents get weight loss surgery

Weight loss surgeries among adolescents jumped 15% between 2021 and 2023, a UT Southwestern Medical Center study found. In 2018, 9.1% of adolescents had Class II or III obesity, which is associated with a range of health issues.  “Severe obesity is very common, much more common than it should be, and it is unlikely to … Read more