Study finds bariatric surgery declined with rise in GLP-1 drugs to treat obesity
A new study has examined a large sample of privately insured patients with obesity and found that use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as anti-obesity medications more than
Are GLP-1 Drugs Putting an End to Bariatric Surgery?
(MedPage Today) —
In this video, Mikhail Varshavski, DO, who goes by “Dr. Mike” on YouTube, talks with Christine J. Ren-Fielding, MD, of NYU Langone Health in New York
ADA Advises Against Compounded GLP-1s; Growth Hormone Therapy Guide; T1D Outcomes Up
(MedPage Today) — The American Diabetes Association (ADA) urged healthcare providers against prescribing non-FDA approved compounded GLP-1 and dual GIP/GIP-1 receptor agonists for type 2 diabetes or obesity and instead
STAT+: Pharmalittle: We’re reading about menopause treatments, Novo plans for Wegovy in India, and more
Researchers presented new evidence that hormone therapy can be beneficial to menopausal women’s heart health
Why do Ozempic and Wegovy seem to treat everything?
From Alzheimer’s disease to depression to heart disease, Ozempic and other GLP-1 agonist drugs appear to offer a solution. Can one type of drug really tackle so many conditions, and
Is Bariatric Surgery at Risk of Becoming Obsolete?
With the advent of GLP-1 analogs, does bariatric surgery have a future role in helping people lose weight? Medscape Medical News
ADA Advises Against Using Compounded GLP-1 RA Medications
In a new guidance statement, the American Diabetes Association advises against the use of unapproved products, warning of safety issues. Medscape Medical News
Curbing plastics pollution could help reduce global burden of breast cancer, analysis suggests
A new study suggests addressing plastic pollution could play a critical role not only in protecting the environment, but also in lowering breast cancer rates, which have been increasing globally,
Olema in deal with Novartis on Kisqali breast cancer combo collaboration
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Ozempic and other weight loss drugs could be making people drink less, study says
Another study suggests that weight-loss meds like Wegovy (NVO) and Mounjaro (LLY) can help people cut back on drinking alcohol.Read more…
Is 1-Week Radiotherapy Safe for Breast Cancer?
A new study found that 1-week ultrahypofractionated radiotherapy regimen for breast cancer was associated with acceptable late toxicities at 1 year. Medscape Medical News
Belly Fat Beats BMI in Predicting Colorectal Cancer Risk
Central obesity demonstrated a stronger association with colorectal cancer risk than general obesity measured using body mass index, according to a large UK cohort study. Medscape Medical News
ASH 2024: New Leukemia Txs, Fewer Blood Clots With GLP-1 Rxs
On tap at ASH this year: Presentations on improved therapies for ALL and CLL and reduced blood clots with weight loss drugs. Medscape Medical News
Tirzepatide Officially Puts GLP-1 Meds on the Map for Obesity-Related Heart Failure
(MedPage Today) — CHICAGO — A long-acting GIP/GLP-1 receptor agonist conferred significant clinical benefit for people with obesity and accompanying heart failure with preserved ejection fraction (HFpEF), according to the
Why some people don’t lose weight with Wegovy
Clinical trials have shown that people using weight-loss jabs, such as Wegovy and Mounjaro, lose anywhere between 16% and 21% of their body weight. But the drugs don’t work for
Does Screening at 40-49 Years Boost Breast Cancer Survival?
A recent analysis suggested improved survival for women screened for breast cancer at ages 40-49, whereas draft guidelines state the harms could outweigh the benefits. Medscape Medical News
Preventing holiday illness and navigating an ‘Ozempic Thanksgiving’
The Fox News Health Newsletter brings you trending and important stories about health care, drug developments, mental health issues, real people’s triumphs over medical struggles, and more.
Selection of Patients With Early-Stage Breast Cancer for Extended Endocrine Therapy
This secondary analysis evaluates the ability of a 70-gene expression risk-of-recurrence assay, to identify the patients with early-stage breast cancer who could benefit the most from prolonged endocrine treatment.
Considerable cost savings from more efficient use of CDK4/6 inhibitors in metastatic breast cancer reported
On November 27, Nature published the results of an innovative breast cancer research project from the Netherlands. This study, the SONIA trial, showed that delaying and shortening the duration of
IG Live December 2: The Weight of Wegovy
(MedPage Today) — MedPage Today spoke with experts during an Instagram Live 2 years ago about the growing buzz around GLP-1 receptor agonists and their role in transforming diabetes and
Research shows death rates linked to obesity-related heart disease are up, especially among men
The rate of deaths from ischemic heart disease related to obesity nearly tripled in the U.S. over a two-decade span, according to new research. The rate for men more than
Tirzepatide shows powerful diabetes-prevention effect in three-year trial
Tirzepatide, a new injectable weight-loss drug, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to
Semaglutide Rocketing Past Statins as Millions Eligible
A new study suggests that 40% of American adults have conditions that could benefit from semaglutide treatment. Medscape Medical News
Thanksgiving on Ozempic: Here’s how to enjoy the meal with a smaller appetite
For people taking Ozempic, Wegovy or other GLP-1 medications, Thanksgiving may look a little different. Experts give tips on how to handle challenges and enjoy the holiday.
How to preserve muscle mass on weight-loss drugs like Wegovy
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GLP-1 Labels Don’t Reflect Trial Exclusions
Clinicians are advised to screen patients for conditions that would have rendered them ineligible to participate in the clinical trials. Medscape Medical News
Cheap Ozempic? How millions of Americans with obesity may get access to costly weight-loss drugs
Millions of obese Americans would get access to popular weekly injectables that would help them shed pounds quickly if a $35 billion proposal from the Biden administration is blessed by
Thyroid Drug & Bone Loss; GLP-1s’ Renal Benefit; Menopause Musculoskeletal Syndrome
(MedPage Today) — The thyroid medication levothyroxine may be associated with bone loss, according to a study that will be presented at the Radiological Society of North America’s annual meeting.<br
Alcohol Use and Antiobesity Medication Treatment
This cohort study examines the association of antiobesity medication use and alcohol use among participants enrolled in a weigh loss program.
Breast Cancer Incidence Still Rising Despite Decline in Death Rates
Despite the decline in death rates from breast cancer among women, the incidence of the disease has continued to rise in the US, by 1% a year from 2012 to
GLP-1 for Treating Obesity: 2024 Lasker-DeBakey Clinical Medical Research Award
In this Viewpoint, 2024 Lasker-DeBakey Clinical Medical Research Award winner Lotte Bjerre Knudsen describes her discovery of glucagon-like peptide-1 for the treatment of patients with obesity.
Biden will move to have Medicare, Medicaid cover GLP-1 weight-loss meds
The outgoing Biden administration will propose that pricey GLP-1 obesity medications such as semaglutide (Wegovy), and tirzepatide (Zepbound) be covered by Medicare and Medicaid.
Amgen says its Ozempic competitor helped patients lose 20% of their weight. Wall Street isn’t impressed
Amgen (AMGN) reported today the highly anticipated results of a mid-stage trial of its experimental weight loss drug and potential Ozempic competitor MariTide, however, Wall Street wasn’t very impressed.Read more…
Ozempic, Wegovy covered by Medicare and Medicaid under Biden admin proposal for anti-obesity GLP-1 drugs
The Biden administration is looking to expand access to anti-obesity GLP-1 drugs like Ozempic and Wegovy for people who have Medicare and Medicaid.
Biden wants to expand access to Ozempic and other popular weight loss drugs
President Joe Biden is trying to expand access to pricey blockbuster drugs in his final months in office.Read more…
Younger Breast Cancer Patients Face Higher Recurrence Risk
A retrospective study found that younger patients with ER-positive, ERBB2-negative breast cancer are more prone to late distant recurrence. Medscape Medical News
GLP-1 RA Drugs Benefit People With SLE, Lupus Nephritis
The glucose-lowering and weight-reducing drug class appears to benefit the heart and kidneys in people with lupus and lupus nephritis, independently of glucose-lowering and weight loss. Medscape Medical News
The Scan by 2 Minute Medicine®: Versatile Ozempic, Healthcare Reform, Unlocking the Brain, and Chickens and the Next Pandemic:
The Scan by 2 Minute Medicine® is a pop-culture medical newsletter and exclusive benefit for 2 Minute Medicine Plus subscribers. We begin with a discussion about Ozempic’s potential in treating
Biden wants drugs like Wegovy, Ozempic covered by Medicare, Medicaid
Millions of Americans would be eligible to have popular weight-loss drugs like Wegovy or Ozempic covered by Medicare and Medicaid under a rule the Biden administration has proposed.
Medicare moves to expand coverage for weight-loss drugs Wegovy, Zepbound
The Biden administration is proposing a major expansion of how Medicare and Medicaid cover the weight-loss drugs Wegovy and Zepbound.
Inside the telehealth-fueled GLP-1 alternative market
How does the market for compounded GLP-1 drugs work? Let us explain.
West Virginia ends GLP-1 subsidy program, leaving many unable to afford the drugs
In 2020, West Virginia started a pilot program providing subsidies for GLP-1 weight loss drugs for state employees. It showed promising results, but the program ended in March, leaving many
West Virginia ends promising subsidy program for GLP-1 weight loss drugs
In 2020, West Virginia launched a pilot program to subsidize GLP-1 drugs for public employees, but the program was shuttered in March.
Metabolic and bariatric surgery safe and effective for patients with severe obesity, study finds
A multicenter examination of data demonstrates that for patients with a body mass index at or above 70 kg/m2 metabolic and bariatric surgery is a potent intervention.
Exclusive-Thousands Turn to Wegovy Copies Each Month as FDA Considers Shortage Status
More than 200,000 prescriptions for copies of Novo Nordisk’s weight-loss drug Wegovy are getting filled by U.S. patients each month, an industry group told the U.S. drugs… Reuters Health Information
As many as 1 in 5 people won’t lose weight with GLP-1 drugs, experts say
About 20% of patients — as many as 1 in 5 — may not respond well to medications like Mounjaro and Wegovy, according to several obesity experts.
Scientists discover why breast cancer drug works better for some people
A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug. The finding, published in
Taking a GLP-1 medication? Expert offers tips for holiday eating
So, you have managed to shed 30 pounds with the help of one of the new blockbuster GLP-1 drugs, but as the holidays near you worry about how to handle
Stroke guidelines updated, with focus on women and GLP-1s
Women, especially those who had high blood pressure during pregnancy or entered menopause before age 45, are among those with a greater risk for stroke.
More than half of US adults could benefit from GLP-1 medications, researchers find
In a new analysis of national data, researchers at the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) estimated that 137
AI detects woman’s breast cancer after routine screening missed it: ‘Deeply grateful’
A U.K. woman had her breast cancer detected through AI after a routine mammogram came back as normal. Experts Drs. Nicole Saphier and Harvey Castro discuss the power of AI
Can RFK Jr. Limit Ozempic Access as HHS Chief? Here’s What to Know
President-elect Donald J. Trump is set to nominate Robert F. Kennedy Jr. to lead the Health and Human Services Department, where he would have limited power over drugs.
6 Natural Ozempic Alternatives That Can Help Quiet ‘Food Noise’
Several healthy habits can help you naturally manage hunger and quiet “food noise” without medication. FG Trade Latin/Getty Images
“Food noise” is not a clinical term but generally refers to
Is Contaminated Drinking Water Tied to HR+ Breast Cancer?
A natural experiment enabled the study of whether high levels of perfluoroalkyl substances were linked to the onset of hormone receptor-positive breast cancer. Medscape News UK
As GLP-1 Use Surges, Clinicians Weigh Benefits and Risks
GLP-1 RAs to assist with weight loss have exploded in popularity. Researchers are working to identify which patients will benefit from them and their associated risks. Medscape Medical News
Oura rings to track blood sugar, Vaccines vs RFK Jr., and Ozempic 2.0: Pharma news roundup
Oura smart rings will soon be able to help users track their blood sugar levels through a new partnership with Dexcom (DXCM), the maker of the U.S.’s first over-the-counter continuous
Metabolic and bariatric surgery safe and effective for patients with severe obesity
A team of researchers led by Pennington Biomedical Research Center’s Dr. Florina Corpodean has confirmed through a data analysis that metabolic and bariatric surgery is largely safe and effective for
Hims & Hers closes up 10% as Lilly tirzepatide compounding dispute resolution delayed
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How anti-obesity drugs are linked to food waste
Taking anti-obesity drugs has led some U.S. adults to throw away more food than they tossed before starting the medications, a new study has found.
Heterogeneity of Residual Disease After Neoadjuvant Systemic Therapy in Breast Cancer
This review analyzes the heterogeneity of residual disease after neoadjuvant systemic therapy in patients with breast cancer.
Radiation-Associated Secondary Cancer in Patients With Breast Cancer
This cohort study examines the risk of radiation-associated sarcoma in patients with breast cancer harboring germline TP53 variants.
Which Breast Cancer Patients Can Skip Postop Radiotherapy?
The POLAR genomic signature can help predict the patients with early breast cancer who may benefit from adjuvant radiotherapy and who may not. Medscape Medical News
In aggressive form of breast cancer, response to therapy may contribute to tumor regrowth, study finds
A recent study by a team of researchers at Vanderbilt University found that response to radiation therapy for triple negative breast cancer (TNBC)—one of the most aggressive forms of the
Weight-loss drug tirzepatide may lower heart failure deaths
A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows.
‘Watershed Moment’: Semaglutide Effective in MASH
The GLP-1 receptor agonist improved both histology and fibrosis in patients, with additional improvements in their liver enzymes, noninvasive fibrosis markers, and cardiometabolic measurements. Medscape Medical News
Side Effects of GLP-1 Drugs: What Doctors Should Know
Popular weight loss drugs have been linked to gastrointestinal, mental health, and vision problems, but the benefits appear to outweigh the risks. Medscape Medical News
Cancer-like mutations in healthy cells point to origins of breast cancer
Researchers have pinpointed what could be the early genetic origins of breast cancer — cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators
Healthy women have cells that resemble breast cancer
A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking
Healthy women have cells that resemble breast cancer, study finds
A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities
‘A Watershed Moment’: GLP-1 Drug Succeeds in Late-Stage MASH Trial
(MedPage Today) — Semaglutide (Wegovy) improved liver fibrosis in patients with metabolic dysfunction-associated steatohepatitis (MASH) and led to greater rates of MASH resolution, an interim analysis of a phase III
American College of Surgeons Operative Standards and Breast Cancer Outcomes
This cohort study evaluates the potential association of the American College of Surgeons operative standards for cancer surgery with short-term oncologic outcomes in breast cancer.
Weight loss drug makers want more insurance plans to cover Wegovy and Zepbound
Weight-loss drug makers are directly targeting employers in a campaign to expand health insurance coverage of their popular, but pricey, medications.Read more…
GLP-1 Use Prior to Surgery: Analyzing the Updated Guidance
(MedPage Today) — Since the modern practice of anesthesia has evolved, providers have been concerned about pulmonary aspiration — when gastric contents enter the lung, resulting in severe complications including
Novo semaglutide data in MASH could negatively impact Madrigal’s Rezdiffra
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Cancer-like mutations in healthy cells point to genetic origins of breast cancer
Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of
#Visual Abstract: Semaglutide Imrpoves Weight Loss Gains and Pain Related to Knee Osteoarthritis in Patients with Obesity
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc.
Food Retention With GLP-1s May Vary by Endoscopic Procedure
A study found that GLP-1 RA use is linked to risks for retained gastric contents during single endoscopic procedures but not with combined upper endoscopy and colonoscopy. Medscape Medical News
Wondr Health Expands Weight Loss Program with Support for GLP-1 Users
What You Should Know: – Wondr Health, a leader in virtual metabolic health programs, has announced the expansion of its weight and obesity care solution, Wondr Plus. – The enhancement
Small Benefit, Persistent Toxic Risk With Adjuvant Anthracycline in Breast Cancer
(MedPage Today) — Adding an anthracycline to adjuvant chemotherapy for TOP2A-normal early breast cancer significantly improved disease-free survival (DFS) but not overall survival (OS) at 10 years, and doubled the
Novo Nordisk semaglutide phase 3 trial for MASH meets primary endpoints
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Breast cancer drug blocked for NHS use in England and Wales after talks collapse
National Institute for Health and Care Excellence unable to reach price agreement with manufacturers of EnhertuA breast cancer charity has said it was “beyond devastated” that talks to make a
Clinical study supports the anti-obesity effects of kimchi
Approximately 16% of the global population, or about 890 million people, suffer from obesity. The World Health Organization (WHO) has recognized obesity as a significant health issue and highlighted its
GLP-1RA and SGLT2 Inhibitor Prescribing in People With Diabetes
This pooled cross-sectional study explores prescribing rates for glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors among US patients with type 1 diabetes.
STAT+: Pharmalittle: We’re reading about a key Merck drug trial, cheap Wegovy in China, and more
Merck reported that a new formulation of Keytruda appears to deliver similar blood levels of the drug when given as a shot as when given intravenously
DR. MARC SIEGEL: Why Ozempic, Wegovy and other GLP-1s could be a magic shot against alcohol abuse
The COVID pandemic set in motion trends with alcohol use that have persisted. Disruptions in work, school and lifestyle have been linked to increased alcohol consumption.
CGM OK’d During Medical Imaging; All Semaglutide Doses Back; Bariatric Surgery Down
(MedPage Today) — Abbott’s FreeStyle Libre 2 and 3 are the first and only patient-applied continuous glucose monitoring (CGM) systems to be approved for use during medical imaging, the company
More than half of US adults are now eligible for Ozempic, Wegovy
About 140 million Americans, more than half of the nation’s adults, could be considered candidates for weight loss drugs Ozempic and Wegovy, according to a new study from JAMA Cardiology.
When or Whether to Give Immunotherapy in Early Breast Cancer
Neoadjuvant immunotherapy offers a survival benefit in specific subtypes of patients but seems to offer no benefit in the adjuvant setting. Medscape Medical News
Pfizer, Arvinas delay late-stage trial for breast cancer therapy
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More than half of U.S. adults could be candidates for Ozempic
More than half of all American adults, almost 137 million people, could be candidates for the blockbuster GLP-1 drug semaglutide, a new analysis finds.
Will Ozempic Crush the Junk-Food Business?
As revolutionary new weight-loss drugs turn consumers off ultraprocessed foods, the industry is on the hunt for new products.
Diabetes meds metformin and GLP-1s can also curb asthma, research finds
Drugs already taken by millions of diabetes patients appear to also help slash asthma attacks by up to 70%, new British research shows.
Anti-obesity drugs, lifestyle interventions show cardiovascular benefits beyond weight loss
Popular anti-obesity drugs continue to show cardiovascular benefits beyond weight loss, according to several new papers published in JACC that are being simultaneously presented at the American Heart Association’s 2024
Over 50% of U.S. Adults Qualify for Ozempic, Wegovy
(MedPage Today) — More than half of all adults in the U.S. are eligible for semaglutide (Ozempic, Wegovy, Rybelsus), researchers estimated.
Among 25,531 participants in the National Health and
Tirzepatide yields sustained weight reduction in obesity and prediabetes, finds study
For patients with obesity and prediabetes, three years of tirzepatide yields substantial and sustained weight reduction and a reduced risk for progression to type 2 diabetes, according to a study
Ozempic: Best and Worst Thanksgiving Foods to Eat While Taking Weight Loss Drugs
Eating some of your favorite Thanksgiving foods while taking drugs like Ozempic and Wegovy may trigger or worsen uncomfortable side effects. The Good Brigade/Getty Images
Eating certain foods can exacerbate
Novo Nordisk reportedly launches Wegovy in China
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Lilly, Incyclix to work on Verzenio combo treatment for breast cancer
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7 Foods And Drinks You Should Avoid While Taking Ozempic—And Why It Matters For Your Results
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Exenatide, a GLP-1 analog, by IV during cardiac surgery did not reduce organ injury or death
A large-scale clinical trial found that intravenous infusion of exenatide, a glucagon-like peptide-1 (GLP-1) analog medication, during heart surgeries involving bypass did not significantly reduce the risk of death, stroke