
Wellness Apps, Medically Tailored Meals Help Slow Weight Gain After GLP-1s
Sunday, October 11 – Recent research shows that structured support may help with weight maintenance after stopping GLP-1s. licensed miniseries · E+/Getty
Most people regain a significant portion of the

Eli Lilly Says Weight Clinic ‘Mocks’ FDA With Illegal Drugs
Satureday, October 10 – Eli Lilly and Co. has sued an Arizona weight loss clinic and three online sellers, alleging they are illegally selling products containing the pharmaceutical giant’s investigational

HHS’ need for R&D speed; weird GLP-1 side effects
Satureday, October 10 – HHS is cranking up its efforts to accelerate drug development; more reports are emerging about off target effects of obesity drugs.

Detached Nails More Than 4 Times Higher Among GLP-1 Users, Study Finds
Friday, October 9 – In a new study, GLP-1 users reported nail detachment more than four times as often as nonusers. Waishaw/Getty Images
GLP-1 drugs like Ozempic have been linked

Oral GLP-1 Orforglipron (Foundayo) Achieves Weight Loss for Women of All Ages
Thursday, October 8 – A new analysis found that the diabetes medication orforglipron (Foundayo), an oral GLP-1, helped women lose weight regardless of their menopausal status. Healthline/Photo by Eli Lilly

Switching from GLP-1 Injections to Wegovy Pill Shows Additional Weight Loss of 4.1%
Thursday, October 8 – Recent research shows people who switch to the Wegovy pill from a GLP-1 injection can lose additional weight. PixelsEffect · E+/Getty
People with overweight or obesity

Survodutide delivers weight loss and glycemic gains in phase 2 trial
Thursday, October 8 – Boehringer reports cardiometabolic improvements in people with t2d

“The Biggest Change Isn’t Even The Weight”: People Are Revealing The Shocking Changes In Loved Ones On GLP-1s That No One Talks About
Thursday, October 8 – “She definitely wasn’t the same person after starting GLP-1s.”View Entire Post ›

Pilot trial suggests structured support may help limit weight regain after GLP-1 treatment
Thursday, October 8 – Glucagon-like peptide-1 (GLP-1) receptor agonists are effective treatments for obesity, but discontinuation is common due to cost, insurance coverage limitations, side effects, patient preference and other

Squats and Planks for BP Lowering; DCBs Compared Head to Head; GLP-1s for HFpEF?
Thursday, October 8 – (MedPage Today) — Isometric exercise training — such as squats and plank exercises — was best done three times a week for short-term blood pressure (BP)-lowering

Menopause Tracking Wearables; Teen GLP-1 Prescribing; Iatrogenic Menopause Risks
Thursday, October 8 – (MedPage Today) — What menopause-related information can be tracked by wearable devices such as Apple watches? (New York Times)
GLP-1 medication prescribing surged from 2017

Increasing Ozempic Dose Linked to Lower Heart Risk Than Switching to Mounjaro
Tuesday, September 6 – Recent research suggests that increasing your Ozempic dose may offer greater heart protection than switching to Mounjaro. Eva Kongshavn · Moment/Getty
A real-world study found that

No detectable increase in pregnancy risks after GLP-1 exposure around conception, largest review to date finds
Tuesday, September 6 – Exposure to GLP-1 weight-loss and diabetes drugs around conception is not linked to a clearly detectable increase in adverse outcomes for mothers or babies, according to

Trump’s Latest Name For GLP-1s Has Doctors And Patients Raising An Important Concern
Tuesday, October 6 – Despite the president’s comments, patients say these medications have been life-changing, and their effectiveness cannot be ignored.

Eli Lilly’s best-ever weight loss data; Sanofi, Regeneron re-up for $1B upfront; and more
Sunday, October 4 – Welcome back to another edition of Endpoints Weekly! It’s October 3rd, the day he asked me what day it was. “It’s October 3rd,” I told him.

AA: Pulmonary aspiration, regurgitation under anesthesia more likely with GLP-1 RAs
Saturday, October 3 – In the United Kingdom, 2.9% of patients undergoing anesthesia reported receiving glucagon-like peptide-1 receptor agonists (GLP-1 RAs), according to a study published online Sept. 16 in

Retatrutide Delivers Substantial Weight Loss in Type 2 Diabetes
Saturday, October 3 – (MedPage Today) — The investigational triple agonist retatrutide substantially improved glycemic control and body weight in adults with obesity and type 2 diabetes, a phase III

Kailera, Hengrui’s GLP-1/GIP candidate delivers weight, menstrual benefits to women with PMOS
Saturday, October 3 – Kailera Therapeutics and Hengrui Pharma’s weekly injection showed benefits beyond weight loss in a mid-stage trial, leading to more regular menstrual cycles in patients with polyendocrine

GLP-1s Tied to Detached Fingernails in New Study
Friday, October 2 – (MedPage Today) — Users of GLP-1 receptor agonists had as much as fourfold higher likelihood for nail disorders, particularly onycholysis (separation of the fingernails or toenails),

GLP-1 prescriptions for new mothers have increased sharply
Friday, October 2 – More U.S. women are being prescribed GLP-1 medications after giving birth, particularly those diagnosed with diabetes, according to new research from the USC Schaeffer Center for

Novel GIP/GLP-1 Yields Uneven Findings in Diabetes Patients With Obesity
Friday, October 2 – (MedPage Today) — An investigational dual GIP/GLP-1 agonist achieved modest weight loss in adults with type 2 diabetes and obesity, the phase III SYNCHRONIZE-2 trial showed,

More New Moms Are Starting GLP-1 Drugs
Friday, October 2 – (MedPage Today) — Starting a GLP-1 receptor agonist after giving birth is becoming more common, an analysis of claims data showed.
The percentage of women

Nurse Choked With Stethoscope; $15M Award for Blinded Patient; Fake Ozempic Charges
Friday, October 2 – (MedPage Today) — In upstate New York, a nurse was choked with a stethoscope by a patient in the emergency room, according to police. (Syracuse.com)

#EASD26: Regeneron’s antibody helps patients regain muscle after stopping GLP-1 therapy
Thursday, October 1 – MILAN — Regeneron’s investigational drug helped obesity patients who stopped taking Novo’s Wegovy regain a similar amount of muscle mass to what they lost when they

Opinion: I studied GLP-1 use in children. The results are reassuring
Thursday, October 1 – “Intervening in childhood could save children from decades of irreversible damage,” a transplant surgeon writes of GLP-1 weight loss drugs.

Women are and will be the predominant users of GLP-1 users, but research gaps remain critical
Thursday, October 1 – The second of a Series of papers presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept

Real-world findings suggest GLP-1 drugs offer health benefits for young people with diabetes
Thursday, October 1 – New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, from Sept. 28–Oct. 2 examined the

Nail detachment over four times more common among GLP-1 users, first controlled study finds
Thursday, October 1 – Nail detachment is more than four times as common among people taking GLP-1 receptor agonists as among comparable people with obesity or type 2 diabetes who

Trevogrumab (anti-myostatin) can help preserve lean mass during and after semaglutide-induced weight loss
Thursday, October 1 – New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, and in press

New Easier-to-Use GLP-1 Pill Safe for the Heart, Study Says
Thursday, October 1 – (MedPage Today) — Orforglipron (Foundayo) was able to claim cardiovascular safety based on the ACHIEVE-4 trial, though heart benefits remain unproven.
Among adults with type

Two charged in scheme to sell counterfeit Ozempic—how you can spot fake meds
Thursday, October 1 – Federal prosecutors have charged two people in an alleged scheme to bring fake versions of the type 2 diabetes drug Ozempic from China and sell them

No Clear Risks With GLP-1s Around Pregnancy, but Caution Urged
Thursday, October 1 – (MedPage Today) — Use of GLP-1 receptor agonists around pregnancy did not appear to increase adverse maternal or perinatal outcomes, according to two studies.
In

Experimental obesity drug targets appetite through amylin, offering potential alternative to GLP-1 therapies
Thursday, October 1 – New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept. 28–Oct. 2), and published in

Higher GLP-1 costs lead to lower adherence
Thursday, October 1 – Semaglutides, or GLP-1s, can produce substantial weight loss if individuals adhere to their doctor’s instructions. But a new study from the University of Georgia suggests patients

Superior weight loss, blood sugar control propel Lilly’s amylin-GIP/GLP-1 combo into Phase 3
Thursday, October 1 – EloraTZP—a combination of an amylin asset and Eli Lilly’s approved obesity drug Zepbound—made a clean sweep of the primary and secondary endpoints in a mid-stage trial

STAT+: Eli Lilly’s Zepbound combined with amylin drug led to significant weight loss in mid-stage trial
Thursday, October 1 – An investigational combination therapy from Eli Lilly led to significant weight loss in a mid-stage study, but high discontinuation rates raise questions about tolerability.

GLP-1s appear safe for treating diabetes in pregnancy, but evidence gaps remain
Thursday, October 1 – New research to be presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept. 28–Oct. 2), and

Lilly builds commercial case for GLP-1 products over Novo with indirect analyses
Thursday, October 1 – Eli Lilly’s weight loss pill Foundayo has had a “slower-than-hoped” launch, according to BMO Capital Markets, which contended that the indirect comparison data—despite falling short of

New Weight Loss Drug Shows Promising Results Over GLP-1s
Thursday, October 1 – New trial data for the weight loss drug called retatrutide shows it helped people living with obesity and type 2 diabetes lose up to 50lbs or

GLP-1s and Stroke
Wednesday, September 30 – (MedPage Today) — GLP-1s and Stroke

Thyroid Drug Recall Most Serious; GLP-1s and Vitamin Deficiency; New T1D Guidelines
Wednesday, September 30 – (MedPage Today) — The FDA designated Vitruvias Therapeutics’ recall of a lot of 30-mg levothyroxine-liothyronine tablets (Thyroid Tablets) as Class I, its most serious classification. (USA

Regulator-mandated study finds no link between semaglutide use and pancreatic cancer
Tuesday, September 29 – New research presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, found no link

How much do Americans spend on GLP-1 medications? Medical students measure drug affordability
Tuesday, September 29 – The number of people using GLP-1 treatments like Ozempic and Wegovy for weight loss or chronic conditions has increased rapidly, with more than 1 in 10

STAT+: Pharmalittle: We’re reading about GLP-1s becoming lifestyle drugs
Tuesday, September 29 – Once promoted as tools to address obesity as a medical issue, GLP-1 drugs are increasingly being marketed as a way to look and feel better

STAT+: Once described as obesity medicines for ‘patients,’ GLP-1s are increasingly lifestyle drugs for ‘customers’
Tuesday, September 29 – Blockbuster GLP-1 drugs have transformed the lives of millions of people. Lately, they’re undergoing a makeover of their own.

Millions more people with overweight could benefit from GLP-1 drugs to protect heart health, study suggests
Monday, September 28 – New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, makes a

Does GLP-1 use result in significant hair loss?
Monday, September 28 – Experts share what you need to know about GLP-1-related hair loss as the side-effect gets more attention from researchers About 20 million people across the US,

Daily oral GLP-1 medication linked to similar weight loss across three menopausal stages
Sunday, September 27 – New analyses to be presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, show

Zepbound and Mounjaro may turn on the body’s calorie-burning brown fat
Sunday, September 27 – Tirzepatide, sold as Mounjaro and Zepbound, activated calorie-burning brown fat in obese mice, revealing a potential metabolic effect beyond appetite suppression. If confirmed in humans, the

How GLP-1 weight-loss drugs are changing fast-food menus
Saturday, September 26 – Chipotle, McDonald’s and Shake Shack are among the restaurant chains revamping their menus as more consumers go on weight-loss drugs.

GIPC1 inhibitor exhibits preclinical efficacy in pancreatic ductal adenocarcinoma
Saturday, September 26 – Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a reported 5-year survival rate of approximately 13.3%, largely because of late diagnosis, rapid progression and resistance

Mylan Wants Del. Judge To Clear Wegovy Generic Drug
Friday, September 25 – Mylan Pharmaceuticals Inc. has launched a lawsuit in Delaware federal court asking for a finding that its proposed generic version of Novo Nordisk Inc.’s blockbuster weight

FDA slams GLP-1 compounder over risk of contaminating drugs ‘with filth’
Friday, September 25 – FDA inspectors found evidence that the compounding pharmacy was making versions of Eli Lilly’s tirzepatide and Novo’s semaglutide “regularly or in inordinate amounts” at a site

Health communication expert finds GLP-1 users face stigma within their social circles
Friday, September 25 – People taking popular GLP-1 medications such as Ozempic, Wegovy and Zepbound may face stigma from those closest to them, according to a new study by a

GLP-1 weight loss and diabetes drugs linked to nutritional deficiencies in nearly 1 in 6 children
Friday, September 25 – Children taking GLP-1 medications (such as Victoza, Saxenda, Trulicity, and Ozempic) for weight loss, prediabetes, or type 2 diabetes may face an overlooked risk: nutritional deficiencies.

Weight loss alone does not explain lower heart disease risk for those on semaglutide
Thursday, September 24 – Semaglutide is known to reduce the risk of serious heart disease. However, a new study published in the European Heart Journal suggests that this effect cannot

FDA Warns Pharmacy About Illegal GLP-1 Compounding
Thursday, September 24 – (MedPage Today) — The FDA issued a warning letter this month to Empower Pharmacy over its mass production of compounded GLP-1 weight-loss and diabetes drugs, citing

Woman Details Losing Vision After Taking GLP-1 As Hundreds of Patients Sue Drug Companies
Thursday, September 24 – Woman who used semaglutide and lost vision is among people suing the makers of GLP-1 weight-loss drugs for not being warned about potential vision loss.

Viking achieves ‘maintenance trifecta’ as GLP-1/GIP dual agonist exceeds expectations
Wednesday, September 23 – Viking Therapeutics’ VK2735 met Truist’s “best-case scenario,” with robust weight loss that was largely maintained when patients transitioned to less frequent dosing. Viking’s stock popped more

Novo targets 10-fold jump in oral Wegovy manufacturing capacity by 2030
Wednesday, September 23 – With sales of the oral GLP-1 medicine rising quickly, executives reassured investors that Novo has secured production capacity to support continued growth.

Lilly presents early data supporting GLP-1/GIP candidate’s potential in depression, alcohol use disorder
Wednesday, September 23 – With a trillion-dollar market cap and a wildly successful GLP-1 portfolio, Eli Lilly isn’t resting on its laurels. At the Psych Congress 2026, the company presented

GLP-1 Lawsuits Over Eye Risk; Hospital Oxygen Supply Cut; Top Causes of U.S. Deaths
Wednesday, September 23 – (MedPage Today) — Note that some links may require registration or subscription.
Dozens of Americans sued manufacturers of GLP-1 receptor agonists, claiming the drugmakers failed

Roche’s Carmot asset normalizes blood sugar, cuts weight in Phase 2 diabetes trial
Wednesday, September 23 – The mid-stage readout is one link in a chain of catalysts that analysts were watching for this year from Roche’s metabolic pipeline, which features assets from

Expert Tips for Thriving While on GLP-1 Medications
Wednesday, September 23 – Heidi Skolnik, a sports nutritionist, exercise physiologist and bestselling author, joins TODAY to discuss her latest book, “Your GLP-1 Game Plan,” that is filled with guidance

The Best Strength Training Exercises for People Taking GLP-1s, According to an Expert
Wednesday, September 22 – About 11% of Americans are taking a GLP-1 medication, up considerably from 3% in 2024, according to a recent Gallup poll.

Hundreds of lawsuits filed against some GLP-1 Makers over vision loss
Tuesday. September 22 – Hundreds of Americans are suing GLP-1 drugmakers Novo Nordisk and Ely Lilly, saying they were not adequately warned of the potential danger of vision loss. In

GLP-1s linked to nutritional deficiencies in children
Tuesday. September 22 – Children prescribed GLP-1 medications for weight loss, prediabetes or type 2 diabetes are at risk for nutritional deficiencies—diagnosed in nearly one in six patients (16.8%) within

RNA therapy may help preserve muscle during GLP-1 weight loss
Tuesday, September 22 – GLP-1 drugs have revolutionized obesity treatment, but they can lead people to lose muscle mass along with fat. And when patients stop treatment, they often regain

Stopping Ozempic may raise heart attack and stroke risk
Tuesday, September 22 – A large study suggests the cardiovascular benefits of GLP-1 drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound can disappear surprisingly quickly when treatment stops. After two

Microdosing GLP-1s Like Wegovy, Zepbound May Still Lead to Weight Loss
Saturday, September 19 – Research shows that microdosing GLP-1 medications may still lead to weight loss. Tatsiana Volkava · Moment/Getty
Recent research suggests that people may still lose weight while

Wegovy Benefits Heart Disease Patients Regardless of Frailty
Saturday, September 19 – (MedPage Today) — Frailty did not appear to prevent adults with cardiovascular disease and overweight or obesity from reaping the benefits of semaglutide (Wegovy), a secondary

Ozempic can change your body. Can it change your life?
Saturday, September 19 – Ozempic and other GLP-1 medications can improve blood sugar, weight, and cardiovascular health, but researchers found little evidence that they also improve mental health, employment, marriage,

If you’re on GLP‑1 drugs and plan to fast for Yom Kippur, here’s what you need to know
Friday, September 18 – Millions of people worldwide—as many as 1 in 8 adults in the U.S.—are taking GLP-1 medications, such as Ozempic, Mounjaro, Wegovy and Zepbound, to treat diabetes

Companies illegally selling unapproved Eli Lily weight loss drug Retatrutide online
Thursday, September 17 – Retatrutide, an experimental weight loss drug still undergoing clinical trials at Eli Lily, is being marketed online and illegally sold to U.S. clients, a CBS News

Parties Clash Over Scope Of GIPA In DNA Test-Taker’s Suit
An Illinois federal judge is weighing whether the state’s genetic privacy law protects against disclosing information about people who have taken genetic tests, with a DNA testing company accused of

Elvinix licenses Zealand’s GLP-1/gastrin dual-agonist peptides
Thursday, September 17 – Elvinix Inc. has announced an exclusive license agreement with Zealand Pharma A/S granting Elvinix the rights to develop and commercialize Zealand’s GLP-1/gastrin dual-agonist peptide portfolio.

Early T1D Screening Guide; FDA Clears Mint Patch Pump; GLP-1s and Fertility
Wednesday, September 16 – (MedPage Today) — An international consensus panel outlined the first clinical framework for implementing general-population screening for islet autoantibodies to catch early-stage type 1 diabetes. (Diabetologia)<br

Preserving Muscle During GLP-1 Weight Loss
Tuesday, September 15 – (MedPage Today) — Blockbuster GLP-1 receptor agonists revolutionized obesity management in recent years, driving weight loss of up to 20%.
This weight loss, however, can

STAT+: How $500 explains Republican health policy, and the GLP-1 Rx wave
Tuesday, September 15 – The one health care policy Republicans agree on, and a look at how rural providers are approaching AI.

Popular GLP-1 weight-loss drugs linked to potentially deadly brain disorder
Monday, September 14 – A study linked 15 cases of Wernicke encephalopathy to GLP-1 drugs like Ozempic and Mounjaro, raising concerns about vitamin B1 deficiency risks.

AI uncovers hidden Ozempic side effects across 400,000 Reddit posts
AI analysis of 400,000 Reddit posts found that users of drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound reported unexpected symptoms including menstrual changes, chills, hot flashes, and fatigue. Researchers

Ozempic and Wegovy may raise hair loss risk in some men
GLP-1 drugs such as Ozempic, Wegovy, and Zepbound may increase hair-loss risk by 7% in men who are already genetically susceptible to male-pattern baldness. The findings suggest thinning hair may

Scientists find Ozempic may slow aging itself
Sunday, September 13 – Semaglutide helped older healthy mice live longer while improving memory, muscle function, blood sugar control, and several biological signs of aging. Its effects went beyond those

FDA takes aim at misleading online claims for compounded GLP-1 drugs
Saturday, July 4 – On June 16, 2026, the US Food and Drug Administration (FDA) issued 25 warning letters to various telehealth companies alleging that their websites contained false or

Semaglutide for Weight Loss Without Diabetes: What the Approval Covers, What Programs Skip, and What Results Actually Look Like
Tuesday, May 19 – Semaglutide for Weight Loss Without Diabetes: What the Approval Covers, What Programs Skip, and What Results Actually Look Like