Colon & Rectum Cancer - Obesity Reviews, Recent Papers, and Clinical Trials
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To see all 79 Reviews, go directly to PubMed.
REVIEWS from PubMed – November 11, 2023 Obesity (in title) AND Colon or Rectum (in title) AND Cancer (in title) AND Review
- The Impact of Obesity on Operative Outcomes and Long-Term Oncological Outcomes Following Rectal Cancer Surgery: A Retrospective Single-Center Study April 14, 2026Background: Our aim was to evaluate the impact of obesity on operative and long-term oncological outcomes following rectal cancer surgery. Methods: Single-center retrospective review of all patients that underwent rectal resection for primary rectal adenocarcinoma between 2010 and2020. Divided into two groups based on preoperative body mass index (BMI): obese-BMI ≥ 30 kg/m², non-obese-BMI < […]Dan Assaf
- Association Between GLP-1 Receptor Agonists and the Risk of Colon Cancer in Adults With Type 2 Diabetes or Obesity: A Systematic Review and Network Meta-Analysis February 11, 2026CONCLUSIONS: GLP-1 RAs may be associated with a lower risk of colon cancer in adults with type 2 diabetes mellitus, warranting further validation in trials among high-risk populations.Man Guo
- Obesity, survival, and chemotherapy outcomes in stage IV colorectal cancer: a retrospective study February 5, 2026CONCLUSIONS: Obesity at diagnosis is associated with improved OS in stage IV CRC. Patients with obesity underwent a longer duration of chemotherapy and experienced greater decreases in BMI during this period.Catherine G Tran
- Obesity and colorectal cancer risk: A systematic review and meta-analysis January 29, 2026CONCLUSION: Obesity, diagnosed by a BMI ≥ 30 kg/m², significantly increases the risk of CRC incidence compared to those of a healthy BMI underscoring the importance of focused strategies to prevent obesity as a modifiable risk factor to reduce CRC incidence.Lachlan James Chun-Lok Leung
- Impact of overweight and obesity on gastric and colorectal cancer incidence in the older adults: a nationwide cohort study January 10, 2026CONCLUSIONS: Overweight or obesity are modifiable risk factors for gastrointestinal cancers in the older adults. Maintaining a normal weight through appropriate weight control may have a beneficial effect on the prevention of gastrointestinal cancers in the older adults.Jinju Choi
- Multi-modal molecular and spatial profiling reveals NNT as a prognostic biomarker in obesity-associated colorectal cancer December 28, 2025CONCLUSIONS: Through integrative molecular and spatial analyses, NNT was identified as a potential prognostic biomarker in obesity-associated CRC. This study highlights the importance of combining clinical data with spatial transcriptomics to uncover context-specific tumor biology.Sungjin Park
- The Role of Chinese Medicine as a Complementary Therapy in the Management of Obesity-Associated Colorectal Cancer December 14, 2025BACKGROUND: Colorectal cancer (CRC) has recently been identified as the world's third commonest cause of cancer death, accounting for 900,000 deaths per year. Obesity-related CRC has also been on the rise, with research indicating that increasing body mass index (BMI) is associated with an increased risk of CRC. As a result, there is a need […]Chester Yan Jie Ng
- Vitamin D deficiency, supplementation, and colorectal cancer outcomes: interactions with obesity and risk profiles September 29, 2025BACKGROUND: Vitamin D deficiency, colorectal cancer, and tumor progression are increasingly linked in recent research. Beyond its well-established roles in bone metabolism and immune regulation, vitamin D has emerged as a potential modulator of cancer prevention and prognosis, particularly in colorectal cancer, where deficiency may worsen outcomes.Basmalah Ghazy
- Impact of obesity on the short-term outcomes of robotic surgery for rectal cancer: a Japanese multicenter study August 22, 2025CONCLUSION: Robotic surgery has shown good postoperative outcomes in obese patients, and it may, therefore, be useful in reducing complications, particularly in patients who have undergone prior treatment.Hiroki Katayama
- Evaluating the influence of the obesity paradox on survival outcomes in patients being treated surgically for rectal cancer-a systematic review and meta-analysis August 18, 2025CONCLUSION: Once diagnosed and being treated with curative intent for rectal cancer, patients living with obesity exhibit similar survival outcomes as those living without obesity. This study refutes hypotheses that an 'obesity paradox' is protective for survival in patients with rectal cancer. Given the current obesity epidemic, this concept may warrant incorporation into preoperative counselling.Matthew G Davey
- The impact of sarcopenic obesity on the prevalence and prognosis of non-metastatic colorectal cancer: A systematic review and meta-analysis August 2, 2025CONCLUSION: SO is linked to poorer survival and higher postoperative complications. Routine body composition assessments may aid early SO identification and intervention. Standardized diagnostic criteria and prospective studies are needed to refine prognostic evaluations.Wanping Wang
- Comparative outcomes of intracorporeal and extracorporeal anastomosis following laparoscopic colectomy in patients with obesity with Colon cancer July 11, 2025CONCLUSION: The study revealed that in patients with obesity, IA resulted in faster bowel function recovery, shorter hospital stays, and fewer complications. Furthermore, IA produced better pathological outcomes, characterized by longer specimen lengths and wider safety margins, without compromising 3-year overall and disease-free survival rates. Thus, IA is a safe and feasible anastomosis technique for […]Feng-Ching Tsai
- Weighty matters: Unraveling the impact of obesity on colorectal cancer and nutritional interventions June 7, 2025This narrative review explores the influence of obesity on colorectal cancer, focusing on obesity-related factors, including chronic inflammation, metabolic dysregulation, and gut microbiota imbalance, which collectively create a pro-carcinogenic environment that increases colorectal cancer risk and complicates treatment outcomes. The findings indicate that obesity not only accelerates tumor progression but also presents challenges in colorectal […]Daniel Simancas-Racines
- Impact of Obesity on Cancer-Specific Survival and Overall Survival in Colorectal Cancer June 4, 2025Obesity is a well-established risk factor for colorectal cancer (CRC) development, yet its influence on cancer-specific survival (CSS) and overall survival (OS) remains paradoxical. While obesity correlates with adverse outcomes such as increased recurrence, metastasis, and treatment-related complications, emerging evidence highlights a counterintuitive "obesity paradox," where overweight and moderately obese patients with Body Mass Index(BMI […]Elvis Obomanu
- Impact of obesity on postoperative complications in colorectal cancer surgery: A systematic review and meta-analysis May 24, 2025CONCLUSION: Obesity significantly increases the risk of surgical site infections in colorectal cancer surgery. Although its impact on mortality and gastrointestinal complications remains unclear, implementing preoperative optimization protocols specifically aimed at obesity management could mitigate these surgical risks. The certainty of evidence ranges from low to very low, highlighting the need for high-quality prospective studies […]Gerardo Sarno
- Impact of visceral obesity on postoperative outcomes in colorectal cancer: a systematic review and meta-analysis May 21, 2025CONCLUSIONS: Colorectal cancer patients with VO who have surgery tend to have fewer lymph nodes taken, more problems after surgery, and a higher rate of switching to open surgery.Yulong Wang
- Outcomes of Metabolic and Bariatric Surgery in Populations with Obesity and Their Risk of Developing Colorectal Cancer: Where Do We Stand? An Umbrella Review on Behalf of TROGSS-The Robotic Global Surgical Society February 26, 2025Introduction: Obesity is a chronic disease associated with increased risk for several cancers, including colorectal cancer (CRC), a leading cause of cancer-related mortality. The majority of CRC cases are associated with modifiable risk factors. Metabolic and bariatric surgery (MBS) is a proven, durable, and successful intervention for obesity. This study aimed to evaluate the impact […]Aman Goyal
- Ultra-processed food, obesity, and colon cancer: A systematic review and meta-analysis February 17, 2025CONCLUSION: Consuming ultra-processed foods increases the risk of obesity and colon cancer.Justin Tin
- Prognostic Impact of Sarcopenic Obesity on Postoperative Outcomes in Colorectal Cancer Patients Undergoing Surgery: A Systematic Review and Meta-Analysis January 11, 2025Sarcopenic obesity is a condition in which the coexistence of sarcopenia and obesity may have unfavorable prognostic implications in cancer. This meta-analysis aims to evaluate the effects of sarcopenic obesity on postoperative outcomes in patients undergoing colorectal cancer surgery. A systematic literature search was conducted in the Scopus, PubMed, and Web of Science databases for […]Tuba Nur Yıldız Kopuz
- The role of adipogenic niche resident cells in colorectal cancer progression in relation to obesity January 7, 2025Colorectal cancer (CRC) is the third most common cancer worldwide and has one of the highest mortality rates. Considering its nonlinear etiology, many risk factors are associated with CRC formation and development, with obesity at the forefront. Obesity is regarded as one of the key environmental risk determinants for the pathogenesis of CRC. Excessive food […]Mikołaj Domagalski
To see all 358 Papers, Go directly to PubMed.
RECENT PAPERS from PubMed – November 11, 2023 Obesity (in title) AND Colon or Rectum (in title) AND Cancer (in title)
- The Impact of Obesity on Operative Outcomes and Long-Term Oncological Outcomes Following Rectal Cancer Surgery: A Retrospective Single-Center Study April 14, 2026Background: Our aim was to evaluate the impact of obesity on operative and long-term oncological outcomes following rectal cancer surgery. Methods: Single-center retrospective review of all patients that underwent rectal resection for primary rectal adenocarcinoma between 2010 and2020. Divided into two groups based on preoperative body mass index (BMI): obese-BMI ≥ 30 kg/m², non-obese-BMI < […]Dan Assaf
- At what age should people with obesity start colorectal cancer screening? April 10, 2026The incidence of obesity and early-onset colorectal cancer (CRC) has rapidly increased in recent decades. We estimated CRC risk differences by body mass index (BMI) and derived corresponding BMI-specific CRC screening initiation ages across multiple countries, to help refine the timing of CRC prevention. We based our analyses on population-level CRC incidence data from the […]Teresa Seum
- Global, regional, and national burden of colorectal cancer attributable to central obesity: a population attributable fraction analysis April 10, 2026CONCLUSIONS: Central obesity accounts for a substantial share of the global CRC burden, with large geographical variability. Applying established waist circumference thresholds in surveillance and incorporating central obesity into individual risk stratification may inform more effective CRC screening and prevention strategies.Daniele Piovani
- Association Between GLP-1 Receptor Agonists and the Risk of Colon Cancer in Adults With Type 2 Diabetes or Obesity: A Systematic Review and Network Meta-Analysis February 11, 2026CONCLUSIONS: GLP-1 RAs may be associated with a lower risk of colon cancer in adults with type 2 diabetes mellitus, warranting further validation in trials among high-risk populations.Man Guo
- Visceral obesity-induced METTL27 regulation of the FABP5/PPARD/CPT1A axis in promoting colorectal cancer progression February 6, 2026The incidence of obesity and colorectal cancer (CRC) is rising annually. Obesity, particularly visceral obesity, poses a serious health threat, yet the association of obesity with CRC progression, as well as the role of visceral obesity, remains debated. This study analyzed 394 CRC patients and revealed that both high body mass index (BMI) and visceral […]Shengnan Gao
- Obesity, survival, and chemotherapy outcomes in stage IV colorectal cancer: a retrospective study February 5, 2026CONCLUSIONS: Obesity at diagnosis is associated with improved OS in stage IV CRC. Patients with obesity underwent a longer duration of chemotherapy and experienced greater decreases in BMI during this period.Catherine G Tran
- Impact of visceral obesity on postoperative complications and oncological outcomes in elderly patients with colorectal cancer January 29, 2026CONCLUSION: Visceral obesity significantly increases the risk of postoperative complications in elderly patients with CRC and may adversely affect short-term tumor prognosis. Preoperative risk identification and interventions for abdominal obesity should be strengthened to improve perioperative safety and postoperative rehabilitation quality.Jie Zhou
- Obesity and colorectal cancer risk: A systematic review and meta-analysis January 29, 2026CONCLUSION: Obesity, diagnosed by a BMI ≥ 30 kg/m², significantly increases the risk of CRC incidence compared to those of a healthy BMI underscoring the importance of focused strategies to prevent obesity as a modifiable risk factor to reduce CRC incidence.Lachlan James Chun-Lok Leung
- Trends in colorectal cancer burden attributable to lifestyle in China (1990-2021): based on the global burden of disease study, revealing declining impact of dietary factors and rising influence of tobacco, alcohol, and obesity January 22, 2026CONCLUSIONS: While improved dietary habits have reduced CRC burden in China, rising obesity pose growing threats. Public health policies must prioritize interventions targeting processed meat intake, and weight management to curb future CRC incidence and mortality.Zhaofu Qin
- Utility of Transanal Total Mesorectal Excision in Patients with Obesity and with Low and Middle Rectal Cancer: A Single-Center, Retrospective Cohort Study January 22, 2026CONCLUSIONS: Transanal total mesorectal excision appears to represent a promising strategy for patients with obesity with mid-to-low rectal cancer, offering low conversion and high sphincter preservation rates while maintaining oncologic safety. See Video Abstract.Masanori Sando
- Impact of overweight and obesity on gastric and colorectal cancer incidence in the older adults: a nationwide cohort study January 10, 2026CONCLUSIONS: Overweight or obesity are modifiable risk factors for gastrointestinal cancers in the older adults. Maintaining a normal weight through appropriate weight control may have a beneficial effect on the prevention of gastrointestinal cancers in the older adults.Jinju Choi
- Liquid Chromatography-Tandem Mass Spectrometry-Based Targeted Lipidomic Analysis of Obesity-Related Colorectal Cancer: Potential Roles of the CYP Eicosanoid Pathway January 1, 2026CONCLUSIONS: These findings demonstrate that the CYP eicosanoid pathway is profoundly dysregulated in obesity-related CRC, providing a basis for exploring the roles of this pathway in the development of obesity-related CRC.Lei Lei
- Multi-modal molecular and spatial profiling reveals NNT as a prognostic biomarker in obesity-associated colorectal cancer December 28, 2025CONCLUSIONS: Through integrative molecular and spatial analyses, NNT was identified as a potential prognostic biomarker in obesity-associated CRC. This study highlights the importance of combining clinical data with spatial transcriptomics to uncover context-specific tumor biology.Sungjin Park
- The Role of Chinese Medicine as a Complementary Therapy in the Management of Obesity-Associated Colorectal Cancer December 14, 2025BACKGROUND: Colorectal cancer (CRC) has recently been identified as the world's third commonest cause of cancer death, accounting for 900,000 deaths per year. Obesity-related CRC has also been on the rise, with research indicating that increasing body mass index (BMI) is associated with an increased risk of CRC. As a result, there is a need […]Chester Yan Jie Ng
- Impact of Obesity on Postoperative Outcomes in Transanal Total Mesorectal Excision for Rectal Cancer December 11, 2025CONCLUSIONS: In this multicenter retrospective study, transanal total mesorectal excision resulted in similar conversion and morbidity rates among patients with obesity and nonobese patients. Obesity was associated with a significantly lower 3-year distant recurrence with no differences in other mid-term oncologic outcomes. See Video Abstract.Makda G Zewde
- The Efficacy and Safety of a Preoperative Dietitian-Led Very Low Calorie Diet Clinic for Adults With Obesity for Colorectal Cancer Surgery: A Retrospective Cohort Study December 11, 2025CONCLUSION: A dietitian-led preoperative VLCD clinic intervention achieved weight loss and appears safe. This novel approach may be useful for the preoperative optimisation of colorectal cancer patients with obesity.Rainbow Lai
- Letter to the Editor: Revisiting the Impact of Obesity on Cancer-Specific Survival in Rectal Cancer-Clinical and Translational Implications November 17, 2025No abstractPengyu Han
- Response to the Letter Concerning "Revisiting the Impact of Obesity on Cancer-Specific Survival in Rectal Cancer-Clinical and Translational Implications" November 13, 2025No abstractElvis Obomanu
- Correction: Vitamin D deficiency, supplementation, and colorectal cancer outcomes: interactions with obesity and risk profiles October 15, 2025[This corrects the article DOI: 10.3389/fmed.2025.1657534.].Basmalah Naji
- Colon cancer in Appalachian Kentucky: Unique genetic, microbiome and obesity findings in a cohort comparison October 9, 2025We investigated colon cancer genomics and microenvironmental features in the Appalachian Kentucky population, a group with the highest incidence of colon cancer in the United States. We assessed two inter-related risk factors for colon cancer (obesity and abnormal gut bacterial microbiome) and their genetic associations within this population. To evaluate potential unique characteristics of the […]Zeta Chow
CLinical Trials involving Colorectal Cancer and Obesity
| NCT Number | Study Title | Study URL | Acronym | Study Status | Interventions | Sponsor | Collaborators | Enrollment | Study Type | Locations |
|---|---|---|---|---|---|---|---|---|---|---|
| NCT02843425 | The Beans to Enrich the Gut Microbiome vs. Obesity's Negative Effects (BE GONE) Trial | https://clinicaltrials.gov/study/NCT02843425 | ACTIVE_NOT_RECRUITING | OTHER: Regular Diet|OTHER: Navy Beans (Canned) | M.D. Anderson Cancer Center | 71 | INTERVENTIONAL | University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, United States | ||
| NCT04633512 | Safety and Feasibility of ActivSightTM in Human | https://clinicaltrials.gov/study/NCT04633512 | ENROLLING_BY_INVITATION | DEVICE: ActivSight | Activ Surgical | The University of Texas Health Science Center, Houston|University at Buffalo|Ohio State University | 67 | INTERVENTIONAL | Kaleida Health, University of Buffalo, Buffalo, New York, 14203, United States|Memorial Hermann Texas Medical Center, Houston, Texas, 77030, United States|Memorial Hermann Sugar Land Hospital, Sugar Land, Texas, 77479, United States | |
| NCT02269631 | Legume Diet Satiety Pilot Study | https://clinicaltrials.gov/study/NCT02269631 | COMPLETED | BEHAVIORAL: Legume diet group|BEHAVIORAL: Control diet group|DEVICE: Smartpill|OTHER: legumes | Emory University | 12 | INTERVENTIONAL | Morehouse, Atlanta, Georgia, 30310, United States|Emory ACTSI, Atlanta, Georgia, 30322, United States | ||
| NCT01312467 | Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI | https://clinicaltrials.gov/study/NCT01312467 | COMPLETED | DRUG: metformin hydrochloride | National Cancer Institute (NCI) | 45 | INTERVENTIONAL | Veterans Administration Long Beach Medical Center, Long Beach, California, 90822, United States|University of California Medical Center At Irvine-Orange Campus, Orange, California, 92868, United States|Kaiser Permanente - Sacramento, Sacramento, California, 95825, United States|Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada | ||
| NCT03548948 | Obesity, Iron Regulation and Colorectal Cancer Risk | https://clinicaltrials.gov/study/NCT03548948 | COMPLETED | OTHER: High heme iron diet|OTHER: Low iron diet|OTHER: Plant-based high non-heme iron diet | University of Illinois at Chicago | American Cancer Society, Inc. | 17 | INTERVENTIONAL | University of Illinois at Chicago, Chicago, Illinois, 60608, United States | |
| NCT04780477 | Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer | https://clinicaltrials.gov/study/NCT04780477 | RECRUITING | DIETARY_SUPPLEMENT: Experimental: High Fiber Diet (HFD)|DIETARY_SUPPLEMENT: Healthy American Diet | Emory University | National Cancer Institute (NCI) | 70 | INTERVENTIONAL | Rollins School of Public Health, Emory University, Atlanta, Georgia, 30322, United States | |
| NCT02273206 | Collaborative Care to Reduce Depression and Increase Cancer Screening Among Low-Income Urban Women | https://clinicaltrials.gov/study/NCT02273206 | PCM3 | COMPLETED | BEHAVIORAL: Prevention Care Management for Depression and Cancer Screening|BEHAVIORAL: Prevention Care Management for Cancer Screening | Clinical Directors Network | 802 | INTERVENTIONAL | Lincoln Ambulatory Care Practice, Bronx, New York, 10451, United States|Morrissania Diagnostic and Treatment Center, Bronx, New York, 10452, United States|Morris Heights Health Center, Bronx, New York, 10453, United States|Segundo Ruiz Belvis Diagnostic and Treatment Center, Bronx, New York, 10454, United States|BronwWorks, Bronx, New York, 10456, United States|Urban Health Plan, Bronx, New York, 10459, United States|Montefiore Family Care Center, Bronx, New York, 10467, United States|Good Shepherd Service, Bronx, New York, 10468, United States | |
| NCT04753359 | Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer | https://clinicaltrials.gov/study/NCT04753359 | Bridge CRC | RECRUITING | OTHER: Med|OTHER: WL | University of Illinois at Chicago | National Cancer Institute (NCI) | 232 | INTERVENTIONAL | University of Illinois at Chicago, Chicago, Illinois, 60612, United States |
| NCT00535990 | Minimally Invasive Surgery (MIS) Database for the Purpose of Research | https://clinicaltrials.gov/study/NCT00535990 | COMPLETED | University of California, San Diego | 250 | OBSERVATIONAL | University of California, San Diego, San Diego, California, 92103, United States | |||
| NCT05396846 | My Best GI Eating Study | https://clinicaltrials.gov/study/NCT05396846 | RECRUITING | BEHAVIORAL: Eating Plan 1|BEHAVIORAL: Eating Plan 2|BEHAVIORAL: Eating Plan 3 | University of Michigan | National Cancer Institute (NCI) | 240 | INTERVENTIONAL | University of Michigan, Ann Arbor, Michigan, 48109, United States | |
| NCT03976284 | Garden-fresh Produce and Exercise Reduce Colon Cancer Risk | https://clinicaltrials.gov/study/NCT03976284 | GFPE | UNKNOWN | BEHAVIORAL: Garden-fresh produce and exercise | University of California, Los Angeles | Charles Drew University of Medicine and Science | 21 | INTERVENTIONAL | UCLA Center for Cancer Prevention & Control Research, Los Angeles, California, 90095-6900, United States |
| NCT04068896 | Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy | https://clinicaltrials.gov/study/NCT04068896 | ACTIVE_NOT_RECRUITING | BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|OTHER: Placebo | NGM Biopharmaceuticals, Inc | 75 | INTERVENTIONAL | NGM Clinical Study Site, Tucson, Arizona, 85719, United States|NGM Clinical Study Site, Los Angeles, California, 90048, United States|NGM Clinical Study Site, Los Angeles, California, 90084, United States|NGM Clinical Study Site, Sacramento, California, 98517, United States|NGM Clinical Study Site, San Diego, California, 92123, United States|NGM Clinical Study Site, Santa Monica, California, 90404, United States|NGM Clinical Study Site, Aurora, Colorado, 80045, United States|NGM Clinical Study Site, Washington, District of Columbia, 20007, United States|NGM Clinical Study Site, Miami, Florida, 33136, United States|NGM Clinical Study Site, Chicago, Illinois, 60611, United States|NGM Clinical Study Site, Baltimore, Maryland, 21201, United States|NGM Clinical Study Site, Omaha, Nebraska, 68130, United States|NGM Clinical Study Site, Charlotte, North Carolina, 28204, United States|NGM Clinical Study Site, Cincinnati, Ohio, 45219, United States|NGM Clinical Study Site, Philadelphia, Pennsylvania, 19111, United States|NGM Clinical Study Site, Charleston, South Carolina, 29425, United States|NGM Clinical Study Site, Myrtle Beach, South Carolina, 29572, United States|NGM Clinical Study Site, Nashville, Tennessee, 37203, United States|NGM Clinical Study Site, Dallas, Texas, 75390, United States|NGM Clinical Study Site, Houston, Texas, 77030, United States|NGM Clinical Study Site, Seattle, Washington, 98101, United States|NGM Clinical Study Site, Milwaukee, Wisconsin, 53226, United States | ||
| NCT05732623 | Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer | https://clinicaltrials.gov/study/NCT05732623 | DEMETRA | RECRUITING | BEHAVIORAL: Semi Quantitative Food Frequency Questionnaire (SQFFQ) | San Raffaele University | Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy|Ospedale Civile Guglielmo da Saliceto, Piacenza, Italy|Centro di Riferimento Oncologico di Aviano, Aviano, Italy|Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Bari, Italy|Gastroenterology Unit, University Hospital of Padova, Padova, Italy|Clinical Gastroenterology Unit, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy|IRCCS Arcispedale S. Maria Nuova - Azienda Ospedaliera di Reggio Emilia, Reggio Emilia, Italy|Azienda Ospedaliera San Gerardo di Monza, Monza, Italy|Azienda ULSS5 Polesana, Rovigo, Italy|Istituto Tumori Regina Elena - IRCCS IFO, Roma, Italy|University Hospital of Padova, Padova, Italy|IRCCS De Bellis, Castellana Grotte, Italy|University Hospital HELIOS Klinikum Wuppertal, Center for Hereditary Tumors, University of Witten-Herdecke, Wuppertal, Germany|Hospital of the University of Munich (LMU), Campus Großhadern, Munich, Germany|Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain|Helsinki University Hospital, Helsinki, Finland|Oslo University Hospital (OUS), Institute for Cancer Genetics and Informatics Norwegian Radium Hospital, Oslo, Norway|Department of Medicine University of Chicago Medicine, Illinois, USA|University of Colorado Hospital, CO, USA|University of Michigan Ann Arbor, Michigan, USA|Columbia University Irving Medical Center, New York, NY|The James Comprehensive Cancer Center, Columbus, OH, USA|Ohio State University|Cleveland Clinic Main Campus, Cleveland, OH, USA|Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia | 2300 | OBSERVATIONAL | Department of Medicine-Gastroenterology, Denver Veterans Affairs Medical Center, University of Colorado Hospital, Denver, Colorado, 80045, United States|Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Chicago Medicine, Chicago, Illinois, 60637, United States|Department of Gastrointestinal Surgery, Helsinki University Hospital, Helsinki, Finland|Department of General, Visceral and Transplant Surgery, Hospital of the University of Munich (LMU), Munich, Germany|Gabriela Moslein, Wuppertal, Germany|Prof Giulia Martina Cavestro, MD PhD, Milan, Lombardy, 20132, Italy|Division of Cancer Medicine, Oslo University Hospital (OUS), Institute for Cancer Genetics and Informatics Norwegian Radium Hospital, Oslo, Norway|Department of Gastroenterology, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain |
| NCT00339469 | Effect of High-Legume Diet on Colorectal Cancer Risk | https://clinicaltrials.gov/study/NCT00339469 | COMPLETED | DIETARY_SUPPLEMENT: LIFE | National Cancer Institute (NCI) | 65 | INTERVENTIONAL | Pennsylvania State University, University Park, Pennsylvania, 16802, United States | ||
| NCT06117241 | Reducing Metabolic Dysregulation in Dyads | https://clinicaltrials.gov/study/NCT06117241 | REMEDY | RECRUITING | BEHAVIORAL: IMAGINE HEALTHY | University of South Carolina | 180 | INTERVENTIONAL | University of South Carolina, Columbia, South Carolina, 29208, United States | |
| NCT00653484 | Energy Balance Interventions for Colorectal Cancer Prevention | https://clinicaltrials.gov/study/NCT00653484 | COMPLETED | BEHAVIORAL: Physical Activity|BEHAVIORAL: Energy Restriction|BEHAVIORAL: Physical Activity and Energy Restriction | Vanderbilt University | National Cancer Institute (NCI) | 40 | INTERVENTIONAL | Vanderbilt-Ingram Cancer Center - Cool Springs, Nashville, Tennessee, 37064, United States|Vanderbilt-Ingram Cancer Center at Franklin, Nashville, Tennessee, 37064, United States|Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, 37232-6838, United States | |
| NCT05114798 | Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers | https://clinicaltrials.gov/study/NCT05114798 | RECRUITING | BEHAVIORAL: Time restricted eating|BEHAVIORAL: Calorie Restriction | University of Illinois at Chicago | National Cancer Institute (NCI) | 255 | INTERVENTIONAL | University of Illinois at Chicago, Chicago, Illinois, 60612, United States | |
| NCT04540081 | Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and LivER Cancer | https://clinicaltrials.gov/study/NCT04540081 | CLOVER | RECRUITING | OTHER: Epic Healthy Planet Population Health Module | University of California, Davis | University of California, Irvine | 20000 | INTERVENTIONAL | UC Davis Medical Center, Sacramento, California, 95817, United States |
| NCT01647776 | Screening and Risk Factors of Colon Neoplasia | https://clinicaltrials.gov/study/NCT01647776 | COMPLETED | OTHER: Stool DNA Test|PROCEDURE: biopsies of rectal and colon mucosa|OTHER: Questionnaires | Case Comprehensive Cancer Center | 3315 | OBSERVATIONAL | University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, 44106, United States | ||
| NCT01457976 | A Survey on Attitudes on Financial Incentives | https://clinicaltrials.gov/study/NCT01457976 | WITHDRAWN | University of Pennsylvania | 0 | OBSERVATIONAL | Online survey, Philadelphia, Pennsylvania, United States | |||
| NCT03286699 | Lifestyle Change for Better Health | https://clinicaltrials.gov/study/NCT03286699 | LCBH | ACTIVE_NOT_RECRUITING | BEHAVIORAL: Dietary Intervention|BEHAVIORAL: Physical Activity Intervention | University of Pittsburgh | National Cancer Institute (NCI) | 8 | INTERVENTIONAL | UPMC Shadyside, Pittsburgh, Pennsylvania, 15232, United States |
| NCT00032344 | Long-term Follow-up Study Designed to Evaluate the Relative Risk of Two Colonoscopy Schedules for Patients With Small Polyps | https://clinicaltrials.gov/study/NCT00032344 | COMPLETED | PROCEDURE: Colonoscopy | US Department of Veterans Affairs | 3200 | INTERVENTIONAL | Carl T. Hayden VA Medical Center, Phoenix, Arizona, 85012, United States|Southern Arizona VA Health Care System, Tucson, Tucson, Arizona, 85723, United States|VA Medical Center, Long Beach, Long Beach, California, 90822, United States|VA Palo Alto Health Care System, Palo Alto, California, 94304-1290, United States|VA Medical Center, San Francisco, San Francisco, California, 94121, United States|VA Eastern Colorado Health Care System, Denver, Denver, Colorado, 80220, United States|Edward Hines, Jr. VA Hospital, Hines, Illinois, 60141-5000, United States|VA Medical Center, Minneapolis, Minneapolis, Minnesota, 55417, United States|VA Medical Center, Kansas City MO, Kansas City, Missouri, 64128, United States|VA Medical Center, Durham, Durham, North Carolina, 27705, United States|VA Medical Center, Portland, Portland, Oregon, 97239-2964, United States|VA North Texas Health Care System, Dallas, Dallas, Texas, 75216, United States|VA Medical & Regional Office Center, White River, White River Junction, Vermont, 05009-0001, United States |