Ovary – CancerObesityConnection.org

Ovarian Cancer - Obesity Reviews, Recent Papers, and Clinical Trials

REVIEWS from PubMed – November 12. 2023 – Obesity (in title) AND Ovarian Cancer (in title) AND Review

The role of diet, obesity and body composition in epithelial ovarian cancer development and progression: Mechanisms and therapeutic implications April 11, 2025
Epithelial ovarian cancer (EOC) ranks among the deadliest cancers, with over half of newly diagnosed patients presenting with metastatic disease, highlighting the need for early detection strategies and a deeper understanding of biologic factors that impact EOC progression and treatment response. This paper aims to synthesize the current literature on the association between diet, obesity, […]
Jessica Suratkal
The effects of obesity on surgical complications and postoperative prognosis of epithelial ovarian cancer: a meta-analysis March 28, 2025
OBJECTIVE: To comprehensively evaluate and compare surgical outcomes of obese patients versus non-obese patients for surgical complications and postoperative prognosis due to epithelial ovarian cancer (EOC).
Jingjing Sheng
A Novel Insight into the Role of Obesity-Related Adipokines in Ovarian Cancer-State-of-the-Art Review and Future Perspectives March 13, 2025
Ovarian cancer (OC) is one of the most fatal gynecological neoplasms. Meta-analyses have shown that the relationship between body mass index (BMI) and ovarian cancer incidence was detected in some types of ovarian cancer. Chronic inflammation and excessive accumulation of free fatty acids are key adipose tissue-derived factors initiating cancer development. Cancer cells transform adipose-derived […]
Klaudia Kołakowska
Impact of Obesity and Lysosomal Dysfunction on Chemoresistance in Ovarian Cancer March 28, 2024
Obesity is recognized as a significant risk factor for ovarian cancer, with accumulating evidence highlighting its impact on disease progression and chemoresistance. This review synthesizes current research elucidating the link between obesity-induced lysosomal dysfunction and ovarian cancer chemoresistance. Epidemiological studies consistently demonstrate a positive correlation between body mass index (BMI) and ovarian cancer risk, attributed […]
Boyun Kim
Obesity in children and adolescents and the risk of ovarian cancer: A systematic review and dose-response meta-analysis December 8, 2022
CONCLUSION: Our findings indicate that obesity in children and adolescents is a risk factor for ovarian cancer, and the risk increases with increasing BMI.
Nan Ding
Impact of Obesity on Major Surgical Outcomes in Ovarian Cancer: A Meta-Analysis February 28, 2022
CONCLUSION: Obesity is associated with an increased risk of postoperative complications, especially wound complications and infection after primary ovarian cancer surgery. Obesity may not affect their optimal debulking rates and 30-day mortality in patients undergoing ovarian cancer surgery. Besides, to improve surgical outcomes, an advanced minimally invasive robotic approach seems to be feasible for the […]
Benshuo Cai
Obesity and Energy Substrate Transporters in Ovarian Cancer-Review April 3, 2021
Ovarian cancer is the seventh most common cancer in women. It is characterized by a high mortality rate because of its aggressiveness and advanced stage at the time of diagnosis. It is a nonhomogenous group of neoplasms and, of which the molecular basics are still being investigated. Nowadays, the golden standard in the treatment is […]
Marta Baczewska
Obesity and ovarian cancer risk: A systematic review July 20, 2017
The association between obesity and ovarian cancer risk has been extensively investigated, but studies have yielded inconsistent findings. This review aims to summarise and discuss the evidence generated to date. Articles published in English prior to August 2016 were retrieved from PubMed. Keywords included obesity, overweight, body size, body mass index, waist-hip ratio, waist circumference, […]
Ke Wei Foong
Obesity and Ovarian Cancer December 3, 2016
Ovarian cancer is the most fatal gynecologic cancer and is an important source of cancer-related mortality, particularly in developed countries. Despite substantial research examining adiposity (primarily adult body mass index [BMI]), the overall evidence suggests only a weak positive association between adiposity and risk of ovarian cancer, with stronger associations observed for population-based case-control studies […]
Shelley S Tworoger
The pro-inflammatory effect of obesity on high grade serous ovarian cancer July 18, 2016
CONCLUSION: In HGSC, pro-inflammatory cytokines are influenced by obesity, as differing inter-cytokine correlations were observed based on BMI, possibly due to dysregulation between cytokines in the setting of obesity. Differences in survival and platinum sensitivity were not noted. Future studies are warranted to determine whether obesity may be a modifiable risk factor for poorer outcomes […]
Camille C Gunderson
Surgical morbidity and clinical outcomes in ovarian cancer - the role of obesity September 3, 2015
CONCLUSION: Obesity is associated with increased rates of wound complications and a prolonged hospital stay, but does not appear to affect other operative outcomes including cytoreduction status and 30-day mortality. Therefore, operative management and postoperative care require a multifactorial approach to minimise adverse outcomes.
A Smits
Impact of obesity on secondary cytoreductive surgery and overall survival in women with recurrent ovarian cancer June 4, 2015
CONCLUSIONS: In this cohort of women undergoing SCS for recurrent ovarian cancer, BMI significantly and independently correlated with overall survival. This observation suggests an effect of excess weight on tumor biology and/or response to treatment that is prevalent throughout the disease course.
Arthur-Quan Tran
The role of ovarian sex steroids in metabolic homeostasis, obesity, and postmenopausal breast cancer: molecular mechanisms and therapeutic implications April 14, 2015
Obese postmenopausal women have an increased risk of breast cancer and are likely to have a worse prognosis than nonobese postmenopausal women. The cessation of ovarian function after menopause results in withdrawal of ovarian sex steroid hormones, estrogen, and progesterone. Accumulating evidence suggests that the withdrawal of estrogen and progesterone causes homeostasis imbalances, including decreases […]
Viroj Boonyaratanakornkit
Association between obesity and ovarian cancer November 27, 2014
Obesity is a risk factor for cancer. Epidemiological evidences associate ovarian cancer with obesity. Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer and accounts for a high rate of mortality. The association between ovarian cancer and obesity could be explained by molecular factors secreted by adipose tissue such as leptin. In […]
Macarena Valladares
Obesity and epithelial ovarian cancer survival: a systematic review and meta-analysis May 17, 2014
CONCLUSIONS: Obesity 5 years before ovarian cancer diagnosis and obesity at a young age were associated with poor prognosis. The association between obesity at diagnosis and survival of ovarian cancer patients still remains equivocal. BMI at diagnosis cannot be a prognostic factor for the survival of ovarian cancer patients. Further well-designed studies are needed to […]
Hyo Sook Bae
Obesity and ovarian cancer survival: a systematic review and meta-analysis May 22, 2012
Studies that have examined the association between obesity and ovarian cancer survival have provided conflicting results. We reviewed and quantitatively summarized existing evidence, exploring potentially important sources of variability, such as the timing of body mass index (BMI) assessment and different cutpoints used to categorize BMI. A systematic search of MEDLINE and EMBASE was conducted […]
Melinda M Protani
Effect of obesity on survival of women with epithelial ovarian cancer: a systematic review and meta-analysis of observational studies November 15, 2011
CONCLUSIONS: This study suggests a possible relationship between obesity at early adulthood and higher mortality among patients with ovarian cancer. Further studies are needed to elucidate the harmful effect of obesity on the survival of patients with ovarian cancer.
Hyun-Sik Yang
The effect of obesity on survival in patients with ovarian cancer December 9, 2008
CONCLUSION: Although obesity has been reported as an independent prognostic factor for survival, this data demonstrates that survival rates are similar between obese and non-obese patients when optimal debulking statuses are the same. Therefore, maximal effort should be directed towards optimal debulking obese patients with EOC.
Kellie S Matthews
Obesity and the risk of epithelial ovarian cancer: a systematic review and meta-analysis January 16, 2007
Obesity is a risk factor for several hormone-related cancers but evidence for an effect on risk of epithelial ovarian cancer remains inconclusive. Many studies evaluating this association have had insufficient statistical power to detect modest effects, particularly for histological subtypes of ovarian cancer. We have therefore assembled the published evidence on obesity and ovarian cancer […]
Catherine M Olsen

RECENT PAPERS from PubMed – November 12, 2023 – Obesity (in title) AND Ovarian (in title) and Cancer (in title)

The association between low muscle mass and sarcopenic obesity, survival, and major complications in patients with advanced ovarian cancer undergoing primary cytoreductive surgery: A retrospective study July 31, 2025
CONCLUSION: Sarcopenic obesity was a marker of poor 1-year and 3-year survival in patients with high-grade serous OC. Neither low muscle mass nor sarcopenic obesity was associated with major complications in PCS.
Niina Norppa
The role of diet, obesity and body composition in epithelial ovarian cancer development and progression: Mechanisms and therapeutic implications April 11, 2025
Epithelial ovarian cancer (EOC) ranks among the deadliest cancers, with over half of newly diagnosed patients presenting with metastatic disease, highlighting the need for early detection strategies and a deeper understanding of biologic factors that impact EOC progression and treatment response. This paper aims to synthesize the current literature on the association between diet, obesity, […]
Jessica Suratkal
The effects of obesity on surgical complications and postoperative prognosis of epithelial ovarian cancer: a meta-analysis March 28, 2025
OBJECTIVE: To comprehensively evaluate and compare surgical outcomes of obese patients versus non-obese patients for surgical complications and postoperative prognosis due to epithelial ovarian cancer (EOC).
Jingjing Sheng
CT-based body composition analysis to study the effect of visceral obesity on postoperative complications in ovarian cancer: implications for young patients March 21, 2025
CONCLUSIONS: In young ovarian cancer patients, VO may serve as a predictor for postoperative complications, and appropriate preventive measures may be beneficial in reducing the incidence of postoperative complications.
Shuyue Su
A Novel Insight into the Role of Obesity-Related Adipokines in Ovarian Cancer-State-of-the-Art Review and Future Perspectives March 13, 2025
Ovarian cancer (OC) is one of the most fatal gynecological neoplasms. Meta-analyses have shown that the relationship between body mass index (BMI) and ovarian cancer incidence was detected in some types of ovarian cancer. Chronic inflammation and excessive accumulation of free fatty acids are key adipose tissue-derived factors initiating cancer development. Cancer cells transform adipose-derived […]
Klaudia Kołakowska
Adipocyte-derived CXCL10 in obesity promotes the migration and invasion of ovarian cancer cells December 20, 2024
CONCLUSIONS: Obesity exacerbates the production of CXCL10 from adipose tissues in obese women. CXCL10 is a key hub factor between developments of ovarian cancer and adipose tissues in obese. Targeting adipose-derived CXCL10 or its downstream macrophages may be a potential strategy to alleviate ovarian cancer accompanied by obesity.
Zhe Wang
Impact of obesity on survival outcomes of women with advanced epithelial ovarian cancer in Lagos, Nigeria: a retrospective cohort study October 18, 2024
CONCLUSION: Our findings suggest that obesity negatively impacts OS in patients with EOC, thus highlighting the need to address obesity in the management of EOC by introducing comprehensive, multidisciplinary approaches incorporating weight management and personalized treatment strategies to enhance the prognosis of these patients.
Kehinde S Okunade
A meta-analysis examining the impact of obesity on surgical site wound complications in patients undergoing primary ovarian cancer surgery August 5, 2024
The meta-analysis sought to evaluate and compare the effect of obesity on surgical site wound problems in subjects after primary ovarian cancer surgery. The results found by this meta-analysis were analyzed, and then odds ratio (OR) and mean difference (MD), at 95% confidence intervals (CIs), were calculated. These models might be dichotomous or contentious, random, […]
Mohamed S Imam
Impact of Obesity and Lysosomal Dysfunction on Chemoresistance in Ovarian Cancer March 28, 2024
Obesity is recognized as a significant risk factor for ovarian cancer, with accumulating evidence highlighting its impact on disease progression and chemoresistance. This review synthesizes current research elucidating the link between obesity-induced lysosomal dysfunction and ovarian cancer chemoresistance. Epidemiological studies consistently demonstrate a positive correlation between body mass index (BMI) and ovarian cancer risk, attributed […]
Boyun Kim
Obesity modulates the cellular and molecular microenvironment in the peritoneal cavity: implication for ovarian cancer risk January 24, 2024
INTRODUCTION: Abdominal obesity increases the risk of developing ovarian cancer but the molecular mechanisms of how obesity supports ovarian cancer development remain unknown. Here we investigated the impact of obesity on the immune cell and gene expression profiles of distinct abdominal tissues, focusing on the peritoneal serous fluid (PSF) and the omental fat band (OFB) […]
Amanda A Shea
High-fat diet and obesity are associated with differential angiogenic gene expression in epithelial ovarian cancer November 13, 2023
CONCLUSIONS: HFD and obesity may promote tumor progression via differential modulation of TGFA. We were unable to confirm this finding in the TCGA dataset. Further evaluation of TGFA is needed to determine if this is a target unique to obesity-driven HGSC.
Katherine E Baumann
Visceral obesity determined by CT as a predictor of short-term postoperative complications in patients with ovarian cancer September 12, 2023
CONCLUSION: Visceral obesity is an important risk factor for short-term postoperative complications in patients with advanced ovarian cancer undergoing cytoreductive surgery.
Xianglin Nie
Obesity and prostate cancer screening, incidence, and mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial June 29, 2023
CONCLUSIONS: Within this screened population, individuals with higher BMI had lower risk of prostate cancer diagnosis but higher risk of prostate cancer mortality. As higher BMI was not positively associated with advanced-stage prostate cancer risk, the increased mortality is unlikely to be due to delayed prostate cancer detection.
Lauren M Hurwitz
Impact of obesity on chemotherapy dosing of carboplatin and survival of women with ovarian cancer April 6, 2023
BACKGROUND: The study objective is to examine the impact of obesity on frontline carboplatin dosing in the neoadjuvant and adjuvant settings and to evaluate the association of dosing with survival among epithelial ovarian cancer (EOC) patients.
Alexandra L Martin
Obesity in children and adolescents and the risk of ovarian cancer: A systematic review and dose-response meta-analysis December 8, 2022
CONCLUSION: Our findings indicate that obesity in children and adolescents is a risk factor for ovarian cancer, and the risk increases with increasing BMI.
Nan Ding
Obesity contributes to the stealth peritoneal dissemination of ovarian cancer: a multi-institutional retrospective cohort study July 19, 2022
CONCLUSIONS: Patients with a high BMI had a significantly worse prognosis than those with a normal BMI, and peritoneal adipose tissue may have contributed to this difference.
Shohei Iyoshi
Early adulthood overweight and obesity and risk of premenopausal ovarian cancer, and premenopausal breast cancer including receptor status: prospective cohort study of nearly 500,000 Danish women April 11, 2022
CONCLUSIONS: Obesity was associated with higher incidence of premenopausal ovarian cancer and lower incidence of premenopausal breast cancer.
Aivara Urbute
Impact of Obesity on Major Surgical Outcomes in Ovarian Cancer: A Meta-Analysis February 28, 2022
CONCLUSION: Obesity is associated with an increased risk of postoperative complications, especially wound complications and infection after primary ovarian cancer surgery. Obesity may not affect their optimal debulking rates and 30-day mortality in patients undergoing ovarian cancer surgery. Besides, to improve surgical outcomes, an advanced minimally invasive robotic approach seems to be feasible for the […]
Benshuo Cai
Obesity is a predictive biomarker of poor benefit from single-agent bevacizumab therapy in recurrent ovarian cancer patients November 11, 2021
CONCLUSIONS: This study demonstrated that obesity is a predictive biomarker of poor benefit from single-agent bevacizumab therapy in recurrent ovarian cancer patients. Obesity may be a useful benchmark for the administration of bevacizumab in daily clinical practice.
Hiroyuki Yoshida
Obesity Promotes Tumor Immune Evasion in Ovarian Cancer Through Increased Production of Myeloid-Derived Suppressor Cells via IL-6 September 29, 2021
CONCLUSION: Obesity promotes the expression of the MDSC-related immunosuppressive genes S100A8 and S100A9 by upregulating IL-6, thus promoting tumor immune evasion and metastasis in ovarian cancer.
Qiannan Yang

Clinical Trials involving Ovarian Cancer and Obesity

NCT Number	Study Title	Study URL	Acronym	Study Status	Interventions	Sponsor	Collaborators	Enrollment	Study Type	Locations
NCT01313455	Adrenal Hyperplasia Among Young People With PCOS	https://clinicaltrials.gov/study/NCT01313455		COMPLETED		Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)		96	OBSERVATIONAL	National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, 20892, United States
NCT01475565	Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT01475565		TERMINATED		Virginia Commonwealth University	National Institute on Minority Health and Health Disparities (NIMHD)	2	OBSERVATIONAL	Virginia Commonwealth University Medical Center, Richmond, Virginia, 23298-5051, United States
NCT00341731	Environmental Factors in the Development of Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT00341731		COMPLETED		National Institute of Environmental Health Sciences (NIEHS)			OBSERVATIONAL	NIEHS, Research Triangle Park, Research Triangle Park, North Carolina, 27709, United States\|Virginia Commonwealth University, Richmond, Virginia, 23284, United States
NCT00436865	Insulin and the Polycystic Ovary Syndrome--Weight Reduction Study	https://clinicaltrials.gov/study/NCT00436865		COMPLETED	BEHAVIORAL: Weight loss	Virginia Commonwealth University	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	79	INTERVENTIONAL	Virginia Commonwealth University General Clinical Research Center, Richmond, Virginia, 23298, United States
NCT00444288	PCOS Twin Study - Environmental Factors in the Development of Polycystic Ovary Syndrome, Phase 2	https://clinicaltrials.gov/study/NCT00444288		COMPLETED		National Institute of Environmental Health Sciences (NIEHS)			OBSERVATIONAL	Duke University Medical Center, Durham, North Carolina, 27710, United States
NCT01509066	Healthy Eating for Reproductive Health (HERHealth)	https://clinicaltrials.gov/study/NCT01509066	HERHealth	COMPLETED	OTHER: Diet	University of South Carolina	Academy of Nutrition and Dietetics	18	INTERVENTIONAL	University of South Carolina, Columbia, South Carolina, 29208, United States
NCT00283816	Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy	https://clinicaltrials.gov/study/NCT00283816		COMPLETED	DRUG: Metformin\|DRUG: Oral Contraceptive Pill\|BEHAVIORAL: Lifestyle Management Program\|BEHAVIORAL: Quality of Life Questionnaire\|PROCEDURE: Oral Glucose Tolerance Test\|PROCEDURE: Blood work\|PROCEDURE: Abdominal Ultra Sound\|PROCEDURE: Dual-energy x-ray absorptiometry (DEXA scan)\|DRUG: placebo	University of Rochester		36	INTERVENTIONAL	University of Rochester Medical Center, Rochester, New York, 14642, United States
NCT01079845	A Cooking and Eating Study	https://clinicaltrials.gov/study/NCT01079845	ACES	TERMINATED	BEHAVIORAL: Nutrition Education, Dietary Counseling, and Cooking	Boston Children's Hospital	Thrasher Research Fund	19	INTERVENTIONAL	Children's Hospital Boston, Boston, Massachusetts, 02115, United States
NCT01859663	Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT01859663		RECRUITING		Cornell University	University of Rochester	360	OBSERVATIONAL	Human Metabolic Research Unit, Cornell University, Ithaca, New York, 14853, United States\|Strong Fertility Center, Rochester, New York, 14623, United States\|CRC at University of Rochester Medical Center, Rochester, New York, 14642, United States
NCT01421797	Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation	https://clinicaltrials.gov/study/NCT01421797		ACTIVE_NOT_RECRUITING	DRUG: Dexamethasone\|DRUG: Cortrosyn	University of Virginia	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)\|University of California, San Diego	84	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22902, United States
NCT00928759	Etiological Factors of Obesity-Associated Hyperandrogenemia in Peripubertal Girls	https://clinicaltrials.gov/study/NCT00928759	CRM002	RECRUITING		University of Virginia	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	40	OBSERVATIONAL	University of Virginia, Charlottesville, Virginia, 22908, United States
NCT01422759	Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess	https://clinicaltrials.gov/study/NCT01422759		RECRUITING	DRUG: Spironolactone	University of Virginia		20	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT00719303	Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer	https://clinicaltrials.gov/study/NCT00719303		UNKNOWN	BEHAVIORAL: Behavioral Dietary Intervention\|BEHAVIORAL: Compliance Monitoring\|OTHER: Counseling\|OTHER: Educational Intervention\|BEHAVIORAL: Exercise Intervention\|OTHER: Laboratory Biomarker Analysis\|OTHER: Quality-of-Life Assessment\|OTHER: Questionnaire Administration	Gynecologic Oncology Group	National Cancer Institute (NCI)	1070	INTERVENTIONAL	University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, 35233, United States\|Tennessee Valley Gynecologic Oncology, Huntsville, Alabama, 35805, United States\|Anchorage Associates in Radiation Medicine, Anchorage, Alaska, 98508, United States\|Alaska Breast Care and Surgery LLC, Anchorage, Alaska, 99508, United States\|Alaska Oncology and Hematology LLC, Anchorage, Alaska, 99508, United States\|Alaska Women's Cancer Care, Anchorage, Alaska, 99508, United States\|Anchorage Oncology Centre, Anchorage, Alaska, 99508, United States\|Katmai Oncology Group, Anchorage, Alaska, 99508, United States\|Providence Alaska Medical Center, Anchorage, Alaska, 99508, United States\|Fairbanks Memorial Hospital, Fairbanks, Alaska, 99701, United States\|University of Arizona Cancer Center at Saint Joseph's, Phoenix, Arizona, 85004, United States\|Gynecologic Oncology Group of Arizona, Phoenix, Arizona, 85012, United States\|Saint Joseph's Hospital and Medical Center, Phoenix, Arizona, 85013, United States\|University of Arizona Cancer Center-North Campus, Tucson, Arizona, 85719, United States\|The University of Arizona Medical Center-University Campus, Tucson, Arizona, 85724, United States\|CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas, 71913, United States\|University of Arkansas for Medical Sciences, Little Rock, Arkansas, 72205, United States\|Sutter Auburn Faith Hospital, Auburn, California, 95602, United States\|Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California, 95603, United States\|Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, 94704, United States\|Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, 91505, United States\|Mills-Peninsula Medical Center, Burlingame, California, 94010, United States\|Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California, 95682, United States\|Eden Hospital Medical Center, Castro Valley, California, 94546, United States\|John Muir Medical Center-Concord Campus, Concord, California, 94520, United States\|Sutter Davis Hospital, Davis, California, 95616, United States\|City of Hope Comprehensive Cancer Center, Duarte, California, 91010, United States\|Palo Alto Medical Foundation-Fremont, Fremont, California, 94538, United States\|Kaiser Permanente-Irvine, Irvine, California, 92618, United States\|UC San Diego Moores Cancer Center, La Jolla, California, 92093, United States\|Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, 90027, United States\|Los Angeles County-USC Medical Center, Los Angeles, California, 90033, United States\|USC / Norris Comprehensive Cancer Center, Los Angeles, California, 90033, United States\|Cedars Sinai Medical Center, Los Angeles, California, 90048, United States\|UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California, 90095, United States\|Memorial Medical Center, Modesto, California, 95355, United States\|Palo Alto Medical Foundation-Camino Division, Mountain View, California, 94040, United States\|Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California, 94040, United States\|Saint Joseph Hospital - Orange, Orange, California, 92868, United States\|Palo Alto Medical Foundation Health Care, Palo Alto, California, 94301, United States\|Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, 95661, United States\|Sutter Roseville Medical Center, Roseville, California, 95661, United States\|Sutter Medical Center Sacramento, Sacramento, California, 95816, United States\|University of California Davis Comprehensive Cancer Center, Sacramento, California, 95817, United States\|University of California San Diego, San Diego, California, 92103, United States\|California Pacific Medical Center-Pacific Campus, San Francisco, California, 94115, United States\|Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California, 95065, United States\|Sutter Pacific Medical Foundation, Santa Rosa, California, 95403, United States\|Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California, 94086, United States\|Olive View-University of California Los Angeles Medical Center, Sylmar, California, 91342, United States\|Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California, 95687, United States\|Sutter Solano Medical Center/Cancer Center, Vallejo, California, 94589, United States\|John Muir Medical Center-Walnut Creek, Walnut Creek, California, 94598, United States\|Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, 80012, United States\|The Medical Center of Aurora, Aurora, Colorado, 80012, United States\|University of Colorado Hospital, Aurora, Colorado, 80045, United States\|Boulder Community Hospital, Boulder, Colorado, 80301, United States\|Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, 80304, United States\|Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, 80907, United States\|Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, 80907, United States\|Porter Adventist Hospital, Denver, Colorado, 80210, United States\|Colorado Blood Cancer Institute, Denver, Colorado, 80218, United States\|Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, 80218, United States\|Rocky Mountain Cancer Centers-Midtown, Denver, Colorado, 80218, United States\|SCL Health Saint Joseph Hospital, Denver, Colorado, 80218, United States\|Rocky Mountain Cancer Centers-Rose, Denver, Colorado, 80220, United States\|Rose Medical Center, Denver, Colorado, 80220, United States\|Colorado Cancer Research Program NCORP, Denver, Colorado, 80222, United States\|Mercy Medical Center, Durango, Colorado, 81301, United States\|Southwest Oncology PC, Durango, Colorado, 81301, United States\|Comprehensive Cancer Care and Research Institute of Colorado LLC, Englewood, Colorado, 80113, United States\|Swedish Medical Center, Englewood, Colorado, 80113, United States\|Poudre Valley Hospital, Fort Collins, Colorado, 80524, United States\|Mountain Blue Cancer Care Center, Golden, Colorado, 80401, United States\|North Colorado Medical Center, Greeley, Colorado, 80631, United States\|Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado, 80111, United States\|Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, 80228, United States\|Saint Anthony Hospital, Lakewood, Colorado, 80228, United States\|Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, 80120, United States\|Littleton Adventist Hospital, Littleton, Colorado, 80122, United States\|Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado, 80124, United States\|Sky Ridge Medical Center, Lone Tree, Colorado, 80124, United States\|Longmont United Hospital, Longmont, Colorado, 80501, United States\|Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, 80501, United States\|McKee Medical Center, Loveland, Colorado, 80539, United States\|Parker Adventist Hospital, Parker, Colorado, 80138, United States\|Rocky Mountain Cancer Centers-Parker, Parker, Colorado, 80138, United States\|Saint Mary Corwin Medical Center, Pueblo, Colorado, 81004, United States\|Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado, 81008, United States\|Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado, 80260, United States\|SCL Health Lutheran Medical Center, Wheat Ridge, Colorado, 80033, United States\|Saint Vincent's Medical Center, Bridgeport, Connecticut, 06606, United States\|Danbury Hospital, Danbury, Connecticut, 06810, United States\|University of Connecticut, Farmington, Connecticut, 06030, United States\|Hartford Hospital, Hartford, Connecticut, 06102, United States\|Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, 06105, United States\|Middlesex Hospital, Middletown, Connecticut, 06457, United States\|The Hospital of Central Connecticut, New Britain, Connecticut, 06050, United States\|Yale University, New Haven, Connecticut, 06520, United States\|Beebe Medical Center, Lewes, Delaware, 19958, United States\|Christiana Gynecologic Oncology LLC, Newark, Delaware, 19713, United States\|Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, 19713, United States\|Helen F Graham Cancer Center, Newark, Delaware, 19713, United States\|Medical Oncology Hematology Consultants PA, Newark, Delaware, 19713, United States\|Regional Hematology and Oncology PA, Newark, Delaware, 19713, United States\|Christiana Care Health System-Christiana Hospital, Newark, Delaware, 19718, United States\|Beebe Health Campus, Rehoboth Beach, Delaware, 19971, United States\|Nanticoke Memorial Hospital, Seaford, Delaware, 19973, United States\|Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, 19801, United States\|Florida Hospital Orlando, Orlando, Florida, 32803, United States\|UF Cancer Center at Orlando Health, Orlando, Florida, 32806, United States\|Sarasota Memorial Hospital, Sarasota, Florida, 34239, United States\|Piedmont Hospital, Atlanta, Georgia, 30309, United States\|Northside Hospital, Atlanta, Georgia, 30342, United States\|Augusta University Medical Center, Augusta, Georgia, 30912, United States\|John B Amos Cancer Center, Columbus, Georgia, 31904, United States\|Northside Hospital-Forsyth, Cumming, Georgia, 30041, United States\|Dekalb Medical Center, Decatur, Georgia, 30033, United States\|Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia, 30501, United States\|Central Georgia Gynecologic Oncology, Macon, Georgia, 31201, United States\|Memorial University Medical Center, Savannah, Georgia, 31404, United States\|Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, 31405, United States\|Hawaii Cancer Care Inc-POB II, Honolulu, Hawaii, 96813, United States\|Queen's Medical Center, Honolulu, Hawaii, 96813, United States\|University of Hawaii Cancer Center, Honolulu, Hawaii, 96813, United States\|Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, 96826, United States\|Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, 83706, United States\|Saint Luke's Mountain States Tumor Institute, Boise, Idaho, 83712, United States\|Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho, 83605, United States\|Kootenai Medical Center, Coeur d'Alene, Idaho, 83814, United States\|Walter Knox Memorial Hospital, Emmett, Idaho, 83617, United States\|Saint Luke's Mountain States Tumor Institute - Fruitland, Fruitland, Idaho, 83619, United States\|Idaho Urologic Institute-Meridian, Meridian, Idaho, 83642, United States\|Saint Luke's Mountain States Tumor Institute - Meridian, Meridian, Idaho, 83642, United States\|Saint Alphonsus Medical Center-Nampa, Nampa, Idaho, 83686, United States\|Saint Luke's Mountain States Tumor Institute - Nampa, Nampa, Idaho, 83686, United States\|Kootenai Cancer Center, Post Falls, Idaho, 83854, United States\|Kootenai Cancer Clinic, Sandpoint, Idaho, 83864, United States\|Saint Luke's Mountain States Tumor Institute-Twin Falls, Twin Falls, Idaho, 83301, United States\|Rush - Copley Medical Center, Aurora, Illinois, 60504, United States\|Saint Joseph Medical Center, Bloomington, Illinois, 61701, United States\|Illinois CancerCare-Bloomington, Bloomington, Illinois, 61704, United States\|Illinois CancerCare-Canton, Canton, Illinois, 61520, United States\|Memorial Hospital of Carbondale, Carbondale, Illinois, 62902, United States\|Illinois CancerCare-Carthage, Carthage, Illinois, 62321, United States\|Centralia Oncology Clinic, Centralia, Illinois, 62801, United States\|Northwestern University, Chicago, Illinois, 60611, United States\|Rush University Medical Center, Chicago, Illinois, 60612, United States\|University of Chicago Comprehensive Cancer Center, Chicago, Illinois, 60637, United States\|Carle on Vermilion, Danville, Illinois, 61832, United States\|Cancer Care Specialists of Central Illinois, Decatur, Illinois, 62526, United States\|Decatur Memorial Hospital, Decatur, Illinois, 62526, United States\|Carle Physician Group-Effingham, Effingham, Illinois, 62401, United States\|Crossroads Cancer Center, Effingham, Illinois, 62401, United States\|Illinois CancerCare-Eureka, Eureka, Illinois, 61530, United States\|Illinois CancerCare-Galesburg, Galesburg, Illinois, 61401, United States\|Western Illinois Cancer Treatment Center, Galesburg, Illinois, 61401, United States\|Northwestern Medicine Cancer Center Delnor, Geneva, Illinois, 60134, United States\|Sudarshan K Sharma MD Limted-Gynecologic Oncology, Hinsdale, Illinois, 60521, United States\|Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, 61443, United States\|Illinois CancerCare-Macomb, Macomb, Illinois, 61455, United States\|Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, 61938, United States\|Good Samaritan Regional Health Center, Mount Vernon, Illinois, 62864, United States\|UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois, 60451, United States\|Advocate Christ Medical Center, Oak Lawn, Illinois, 60453-2699, United States\|Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, 61350, United States\|Radiation Oncology of Northern Illinois, Ottawa, Illinois, 61350, United States\|Illinois CancerCare-Pekin, Pekin, Illinois, 61554, United States\|OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, Pekin, Illinois, 61554, United States\|Methodist Medical Center of Illinois, Peoria, Illinois, 61603, United States\|Illinois CancerCare-Peoria, Peoria, Illinois, 61615, United States\|OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois, 61615, United States\|OSF Saint Francis Medical Center, Peoria, Illinois, 61637, United States\|Illinois CancerCare-Peru, Peru, Illinois, 61354, United States\|Valley Radiation Oncology, Peru, Illinois, 61354, United States\|Illinois CancerCare-Princeton, Princeton, Illinois, 61356, United States\|Central Illinois Hematology Oncology Center, Springfield, Illinois, 62702, United States\|Southern Illinois University School of Medicine, Springfield, Illinois, 62702, United States\|Springfield Clinic, Springfield, Illinois, 62702, United States\|Memorial Medical Center, Springfield, Illinois, 62781, United States\|Cancer Care Specialists of Illinois-Swansea, Swansea, Illinois, 62226, United States\|Carle Cancer Center, Urbana, Illinois, 61801, United States\|The Carle Foundation Hospital, Urbana, Illinois, 61801, United States\|Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois, 60555, United States\|Rush-Copley Healthcare Center, Yorkville, Illinois, 60560, United States\|Michiana Hematology Oncology PC-Crown Point, Crown Point, Indiana, 46307, United States\|Elkhart Clinic, Elkhart, Indiana, 46514-2098, United States\|Michiana Hematology Oncology PC-Elkhart, Elkhart, Indiana, 46514, United States\|Elkhart General Hospital, Elkhart, Indiana, 46515, United States\|Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, 46202, United States\|Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana, 46260, United States\|Community Howard Regional Health, Kokomo, Indiana, 46904, United States\|IU Health La Porte Hospital, La Porte, Indiana, 46350, United States\|Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana, 46545, United States\|Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana, 46545, United States\|Michiana Hematology Oncology PC-Plymouth, Plymouth, Indiana, 46563, United States\|Memorial Hospital of South Bend, South Bend, Indiana, 46601, United States\|Michiana Hematology Oncology PC-South Bend, South Bend, Indiana, 46601, United States\|South Bend Clinic, South Bend, Indiana, 46617, United States\|Northern Indiana Cancer Research Consortium, South Bend, Indiana, 46628, United States\|Michiana Hematology Oncology PC-Westville, Westville, Indiana, 46391, United States\|Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, 50325, United States\|Mercy Cancer Center-West Lakes, Clive, Iowa, 50325, United States\|Alegent Health Mercy Hospital, Council Bluffs, Iowa, 51503, United States\|Greater Regional Medical Center, Creston, Iowa, 50801, United States\|Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, 50314, United States\|Mercy Medical Center - Des Moines, Des Moines, Iowa, 50314, United States\|Mercy Medical Center-West Lakes, West Des Moines, Iowa, 50266, United States\|Cancer Center of Kansas - Chanute, Chanute, Kansas, 66720, United States\|Cancer Center of Kansas - Dodge City, Dodge City, Kansas, 67801, United States\|Cancer Center of Kansas - El Dorado, El Dorado, Kansas, 67042, United States\|Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, 66701, United States\|Cancer Center of Kansas-Independence, Independence, Kansas, 67301, United States\|Providence Medical Center, Kansas City, Kansas, 66112, United States\|University of Kansas Cancer Center, Kansas City, Kansas, 66160, United States\|Cancer Center of Kansas-Kingman, Kingman, Kansas, 67068, United States\|Lawrence Memorial Hospital, Lawrence, Kansas, 66044, United States\|Kansas Institute of Medicine Cancer and Blood Center, Lenexa, Kansas, 66219, United States\|Minimally Invasive Surgery Hospital, Lenexa, Kansas, 66219, United States\|Cancer Center of Kansas-Liberal, Liberal, Kansas, 67905, United States\|Cancer Center of Kansas-Manhattan, Manhattan, Kansas, 66502, United States\|Cancer Center of Kansas - McPherson, McPherson, Kansas, 67460, United States\|Cancer Center of Kansas - Newton, Newton, Kansas, 67114, United States\|Menorah Medical Center, Overland Park, Kansas, 66209, United States\|Saint Luke's South Hospital, Overland Park, Kansas, 66213, United States\|Cancer Center of Kansas - Parsons, Parsons, Kansas, 67357, United States\|Kansas City NCI Community Oncology Research Program, Prairie Village, Kansas, 66208, United States\|Cancer Center of Kansas - Pratt, Pratt, Kansas, 67124, United States\|Cancer Center of Kansas - Salina, Salina, Kansas, 67401, United States\|Cancer Center of Kansas - Wellington, Wellington, Kansas, 67152, United States\|Associates In Womens Health, Wichita, Kansas, 67208, United States\|Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, 67208, United States\|Cancer Center of Kansas - Wichita, Wichita, Kansas, 67214, United States\|Via Christi Regional Medical Center, Wichita, Kansas, 67214, United States\|Wichita NCI Community Oncology Research Program, Wichita, Kansas, 67214, United States\|Cancer Center of Kansas - Winfield, Winfield, Kansas, 67156, United States\|Flaget Memorial Hospital, Bardstown, Kentucky, 40004, United States\|Commonwealth Cancer Center-Corbin, Corbin, Kentucky, 40701, United States\|Saint Elizabeth Medical Center South, Edgewood, Kentucky, 41017, United States\|Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, 40504, United States\|Saint Joseph Hospital East, Lexington, Kentucky, 40509, United States\|University of Kentucky/Markey Cancer Center, Lexington, Kentucky, 40536, United States\|Saint Joseph London, London, Kentucky, 40741, United States\|Jewish Hospital, Louisville, Kentucky, 40202, United States\|Norton Hospital Pavilion and Medical Campus, Louisville, Kentucky, 40202, United States\|Norton Suburban Hospital and Medical Campus, Louisville, Kentucky, 40207, United States\|Saints Mary and Elizabeth Hospital, Louisville, Kentucky, 40215, United States\|Jewish Hospital Medical Center Northeast, Louisville, Kentucky, 40245, United States\|Jewish Hospital Medical Center South, Shepherdsville, Kentucky, 40165, United States\|Hematology/Oncology Clinic LLP, Baton Rouge, Louisiana, 70809, United States\|Woman's Hospital, Baton Rouge, Louisiana, 70817, United States\|Tulane University Health Sciences Center, New Orleans, Louisiana, 70112, United States\|Maine Medical Center-Bramhall Campus, Portland, Maine, 04102, United States\|Maine Medical Center- Scarborough Campus, Scarborough, Maine, 04074, United States\|Greater Baltimore Medical Center, Baltimore, Maryland, 21204, United States\|Walter Reed National Military Medical Center, Bethesda, Maryland, 20889-5600, United States\|Tufts Medical Center, Boston, Massachusetts, 02111, United States\|Lahey Hospital and Medical Center, Burlington, Massachusetts, 01805, United States\|University of Massachusetts Memorial Health Care, Worcester, Massachusetts, 01605, United States\|Michigan Cancer Research Consortium NCORP, Ann Arbor, Michigan, 48106, United States\|Saint Joseph Mercy Hospital, Ann Arbor, Michigan, 48106, United States\|University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, 48109, United States\|Bronson Battle Creek, Battle Creek, Michigan, 49017, United States\|Spectrum Health Big Rapids Hospital, Big Rapids, Michigan, 49307, United States\|IHA Hematology Oncology Consultants-Brighton, Brighton, Michigan, 48114, United States\|Saint Joseph Mercy Brighton, Brighton, Michigan, 48114, United States\|IHA Hematology Oncology Consultants-Canton, Canton, Michigan, 48188, United States\|Saint Joseph Mercy Canton, Canton, Michigan, 48188, United States\|Caro Cancer Center, Caro, Michigan, 48723, United States\|IHA Hematology Oncology Consultants-Chelsea, Chelsea, Michigan, 48118, United States\|Saint Joseph Mercy Chelsea, Chelsea, Michigan, 48118, United States\|Hematology Oncology Consultants-Clarkston, Clarkston, Michigan, 48346, United States\|Newland Medical Associates-Clarkston, Clarkston, Michigan, 48346, United States\|Beaumont Hospital-Dearborn, Dearborn, Michigan, 48124, United States\|Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, 48201, United States\|Saint John Hospital and Medical Center, Detroit, Michigan, 48236, United States\|Great Lakes Cancer Management Specialists-Doctors Park, East China Township, Michigan, 48054, United States\|Weisberg Cancer Treatment Center, Farmington Hills, Michigan, 48334, United States\|Genesee Cancer and Blood Disease Treatment Center, Flint, Michigan, 48503, United States\|Genesee Hematology Oncology PC, Flint, Michigan, 48503, United States\|Genesys Hurley Cancer Institute, Flint, Michigan, 48503, United States\|Hurley Medical Center, Flint, Michigan, 48503, United States\|Cancer Research Consortium of West Michigan NCORP, Grand Rapids, Michigan, 49503, United States\|Mercy Health Saint Mary's, Grand Rapids, Michigan, 49503, United States\|Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, 49503, United States\|Great Lakes Cancer Management Specialists-Van Elslander Cancer Center, Grosse Pointe Woods, Michigan, 48236, United States\|Lymphoma Clinic of Michigan, Grosse Pointe Woods, Michigan, 48236, United States\|Michigan Breast Specialists-Grosse Pointe Woods, Grosse Pointe Woods, Michigan, 48236, United States\|Allegiance Health, Jackson, Michigan, 49201, United States\|Borgess Medical Center, Kalamazoo, Michigan, 49001, United States\|Bronson Methodist Hospital, Kalamazoo, Michigan, 49007, United States\|West Michigan Cancer Center, Kalamazoo, Michigan, 49007, United States\|Sparrow Hospital, Lansing, Michigan, 48912, United States\|Hope Cancer Clinic, Livonia, Michigan, 48154, United States\|Saint Mary Mercy Hospital, Livonia, Michigan, 48154, United States\|Great Lakes Cancer Management Specialists-Macomb Medical Campus, Macomb, Michigan, 48044, United States\|Michigan Breast Specialists-Macomb Township, Macomb, Michigan, 48044, United States\|Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan, 48453, United States\|Mercy Health Mercy Campus, Muskegon, Michigan, 49444, United States\|Lakeland Community Hospital, Niles, Michigan, 49120, United States\|21st Century Oncology-Pontiac, Pontiac, Michigan, 48341, United States\|Hope Cancer Center, Pontiac, Michigan, 48341, United States\|Newland Medical Associates-Pontiac, Pontiac, Michigan, 48341, United States\|Saint Joseph Mercy Oakland, Pontiac, Michigan, 48341, United States\|Lake Huron Medical Center, Port Huron, Michigan, 48060, United States\|Spectrum Health Reed City Hospital, Reed City, Michigan, 49677, United States\|Great Lakes Cancer Management Specialists-Rochester Hills, Rochester Hills, Michigan, 48309, United States\|William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, 48073, United States\|Saint Mary's of Michigan, Saginaw, Michigan, 48601, United States\|Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan, 48604, United States\|Lakeland Hospital, Saint Joseph, Michigan, 49085, United States\|Marie Yeager Cancer Center, Saint Joseph, Michigan, 49085, United States\|Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan, 48312, United States\|Saint Joseph Health System-Tawas City, Tawas City, Michigan, 48764, United States\|Munson Medical Center, Traverse City, Michigan, 49684, United States\|William Beaumont Hospital - Troy, Troy, Michigan, 48098, United States\|Advanced Breast Care Center PLLC, Warren, Michigan, 48088, United States\|Bhadresh Nayak MD PC-Warren, Warren, Michigan, 48093, United States\|Great Lakes Cancer Management Specialists-Macomb Professional Building, Warren, Michigan, 48093, United States\|Macomb Hematology Oncology PC, Warren, Michigan, 48093, United States\|Michigan Breast Specialists-Warren, Warren, Michigan, 48093, United States\|Saint John Macomb-Oakland Hospital, Warren, Michigan, 48093, United States\|Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan, 48661, United States\|Metro Health Hospital, Wyoming, Michigan, 49519, United States\|Huron Gastroenterology PC, Ypsilanti, Michigan, 48106, United States\|IHA Hematology Oncology Consultants-Ann Arbor, Ypsilanti, Michigan, 48197, United States\|Sanford Clinic North-Bemidgi, Bemidji, Minnesota, 56601, United States\|Fairview Ridges Hospital, Burnsville, Minnesota, 55337, United States\|Mercy Hospital, Coon Rapids, Minnesota, 55433, United States\|Fairview-Southdale Hospital, Edina, Minnesota, 55435, United States\|Unity Hospital, Fridley, Minnesota, 55432, United States\|Hutchinson Area Health Care, Hutchinson, Minnesota, 55350, United States\|Fairview Maple Grove Medical Center, Maple Grove, Minnesota, 55369, United States\|Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, 55109, United States\|Saint John's Hospital - Healtheast, Maplewood, Minnesota, 55109, United States\|Abbott-Northwestern Hospital, Minneapolis, Minnesota, 55407, United States\|Hennepin County Medical Center, Minneapolis, Minnesota, 55415, United States\|Health Partners Inc, Minneapolis, Minnesota, 55454, United States\|New Ulm Medical Center, New Ulm, Minnesota, 56073, United States\|North Memorial Medical Health Center, Robbinsdale, Minnesota, 55422, United States\|Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota, 55416, United States\|Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, 55416, United States\|Park Nicollet Frauenshuh Cancer Center, Saint Louis Park, Minnesota, 55426, United States\|Regions Hospital, Saint Paul, Minnesota, 55101, United States\|United Hospital, Saint Paul, Minnesota, 55102, United States\|Saint Francis Regional Medical Center, Shakopee, Minnesota, 55379, United States\|Lakeview Hospital, Stillwater, Minnesota, 55082, United States\|Ridgeview Medical Center, Waconia, Minnesota, 55387, United States\|Rice Memorial Hospital, Willmar, Minnesota, 56201, United States\|Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, 55125, United States\|Fairview Lakes Medical Center, Wyoming, Minnesota, 55092, United States\|Saint Dominic-Jackson Memorial Hospital, Jackson, Mississippi, 39216, United States\|Central Care Cancer Center-Carrie J Babb Cancer Center, Bolivar, Missouri, 65613, United States\|Parkland Health Center-Bonne Terre, Bonne Terre, Missouri, 63628, United States\|Saint Francis Medical Center, Cape Girardeau, Missouri, 63703, United States\|Southeast Cancer Center, Cape Girardeau, Missouri, 63703, United States\|Centerpoint Medical Center LLC, Independence, Missouri, 64057, United States\|Capital Region Medical Center-Goldschmidt Cancer Center, Jefferson City, Missouri, 65109, United States\|Saint Luke's Hospital of Kansas City, Kansas City, Missouri, 64111, United States\|Heartland Hematology and Oncology Associates Incorporated, Kansas City, Missouri, 64118, United States\|Research Medical Center, Kansas City, Missouri, 64132, United States\|Saint Luke's East - Lee's Summit, Lee's Summit, Missouri, 64086, United States\|Liberty Radiation Oncology Center, Liberty, Missouri, 64068, United States\|Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, 65401, United States\|Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, 65401, United States\|Heartland Regional Medical Center, Saint Joseph, Missouri, 64507, United States\|Saint Joseph Oncology Inc, Saint Joseph, Missouri, 64507, United States\|Barnes-Jewish Hospital, Saint Louis, Missouri, 63110, United States\|Washington University School of Medicine, Saint Louis, Missouri, 63110, United States\|Missouri Baptist Medical Center, Saint Louis, Missouri, 63131, United States\|Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, 63670, United States\|Cancer Research for the Ozarks NCORP, Springfield, Missouri, 65804, United States\|Mercy Hospital Springfield, Springfield, Missouri, 65804, United States\|CoxHealth South Hospital, Springfield, Missouri, 65807, United States\|Missouri Baptist Sullivan Hospital, Sullivan, Missouri, 63080, United States\|Missouri Baptist Outpatient Center-Sunset Hills, Sunset Hills, Missouri, 63127, United States\|Community Hospital of Anaconda, Anaconda, Montana, 59711, United States\|Billings Clinic Cancer Center, Billings, Montana, 59101, United States\|Saint Vincent Healthcare, Billings, Montana, 59101, United States\|Montana Cancer Consortium NCORP, Billings, Montana, 59102, United States\|Bozeman Deaconess Hospital, Bozeman, Montana, 59715, United States\|Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, 59701, United States\|Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, 59405, United States\|Great Falls Clinic, Great Falls, Montana, 59405, United States\|Saint Peter's Community Hospital, Helena, Montana, 59601, United States\|Kalispell Regional Medical Center, Kalispell, Montana, 59901, United States\|Saint Patrick Hospital - Community Hospital, Missoula, Montana, 59802, United States\|Community Medical Hospital, Missoula, Montana, 59804, United States\|CHI Health Saint Francis, Grand Island, Nebraska, 68803, United States\|Heartland Hematology and Oncology, Kearney, Nebraska, 68845, United States\|CHI Health Good Samaritan, Kearney, Nebraska, 68847, United States\|Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, 68510, United States\|Nebraska Methodist Hospital, Omaha, Nebraska, 68114, United States\|Alegent Health Immanuel Medical Center, Omaha, Nebraska, 68122, United States\|Hematology and Oncology Consultants PC, Omaha, Nebraska, 68122, United States\|Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, 68124, United States\|Alegent Health Lakeside Hospital, Omaha, Nebraska, 68130, United States\|Creighton University Medical Center, Omaha, Nebraska, 68131, United States\|Midlands Community Hospital, Papillion, Nebraska, 68046, United States\|Women's Cancer Center of Nevada, Las Vegas, Nevada, 89169, United States\|Center of Hope at Renown Medical Center, Reno, Nevada, 89502, United States\|Renown Regional Medical Center, Reno, Nevada, 89502, United States\|Wentworth-Douglass Hospital, Dover, New Hampshire, 03820, United States\|Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, 03756, United States\|Norris Cotton Cancer Center-Manchester, Manchester, New Hampshire, 03102, United States\|Norris Cotton Cancer Center-Nashua, Nashua, New Hampshire, 03063, United States\|Ocean Medical Center, Brick, New Jersey, 08724, United States\|Cooper Hospital University Medical Center, Camden, New Jersey, 08103, United States\|Hackensack University Medical Center, Hackensack, New Jersey, 07601, United States\|Morristown Medical Center, Morristown, New Jersey, 07960, United States\|Virtua Memorial, Mount Holly, New Jersey, 08060, United States\|Jersey Shore Medical Center, Neptune, New Jersey, 07753, United States\|Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, 08903, United States\|Riverview Medical Center/Booker Cancer Center, Red Bank, New Jersey, 07701, United States\|Overlook Hospital, Summit, New Jersey, 07902, United States\|MD Anderson Cancer Center at Cooper-Voorhees, Voorhees, New Jersey, 08043, United States\|Virtua Voorhees, Voorhees, New Jersey, 08043, United States\|University of New Mexico Cancer Center, Albuquerque, New Mexico, 87102, United States\|Southwest Gynecologic Oncology Associates Inc, Albuquerque, New Mexico, 87106, United States\|Women's Cancer Care Associates LLC, Albany, New York, 12208, United States\|Montefiore Medical Center-Einstein Campus, Bronx, New York, 10461, United States\|M
NCT01422707	Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess	https://clinicaltrials.gov/study/NCT01422707		WITHDRAWN	DRUG: Hydrocortisone	University of Virginia		0	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT00805207	Sex Steroids, Sleep, and Metabolic Dysfunction in Women	https://clinicaltrials.gov/study/NCT00805207	SCOR	COMPLETED	DRUG: Progesterone\|DRUG: testosterone\|DRUG: glucocorticoid\|DEVICE: continuous positive airway pressure\|DRUG: Estrogen\|OTHER: Control	Washington University School of Medicine		61	INTERVENTIONAL	Washington University School of Medicine, Saint Louis, Missouri, 63110, United States
NCT03480022	Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS	https://clinicaltrials.gov/study/NCT03480022	SAXAPCOS	COMPLETED	DRUG: Liraglutide Pen Injector [Saxenda]\|DRUG: Placebo Liraglutide Pen Injector	Woman's	Novo Nordisk A/S	88	INTERVENTIONAL	Woman's Hospital, Baton Rouge, Louisiana, 70817, United States
NCT00757185	Compromised Microcirculation in Women With Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT00757185		COMPLETED	DRUG: ganirelix acetate\|DRUG: methyl testosterone	Yale University	National Heart, Lung, and Blood Institute (NHLBI)	28	INTERVENTIONAL	John B. Pierce Laboratory, New Haven, Connecticut, 06520, United States
NCT04257500	Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS	https://clinicaltrials.gov/study/NCT04257500	RING-PCOS	RECRUITING	DRUG: Etonogestrel/ethinyl estradiol vaginal ring	Andrea Roe, MD, MPH		40	INTERVENTIONAL	University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States
NCT01422733	Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction	https://clinicaltrials.gov/study/NCT01422733		WITHDRAWN	DRUG: Hydrocortisone\|DRUG: dexamethasone\|DRUG: Cosyntropin\|DRUG: rhCG	University of Virginia		0	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT01487486	Proteomics & Glyco-Proteomic Analysis of Follicular Fluid	https://clinicaltrials.gov/study/NCT01487486		UNKNOWN	DRUG: IVF Antagonist Protocol	University of Cincinnati	Merck Sharp & Dohme LLC	30	OBSERVATIONAL	Center for Reproductive Health, Cincinnati, Ohio, 45219, United States
NCT01482286	Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS	https://clinicaltrials.gov/study/NCT01482286	PULSE	TERMINATED	DRUG: Metformin\|BEHAVIORAL: Dietary Restriction\|BEHAVIORAL: Exercise Training	Pennington Biomedical Research Center	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	32	INTERVENTIONAL	Pennington Biomedical Research Center, Baton Rouge, Louisiana, 70808, United States
NCT00704912	Treatment of Hyperandrogenism Versus Insulin Resistance in Infertile Polycystic Ovary Syndrome (PCOS) Women	https://clinicaltrials.gov/study/NCT00704912	OWL-PCOS	COMPLETED	DRUG: Orlistat/Meal Replacement/Lifestyle Modification\|DRUG: Loestrin 1/20\|DRUG: Combination of treatments	Milton S. Hershey Medical Center	University of Pennsylvania	217	INTERVENTIONAL	Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033, United States\|University of Pennsylvania, Department of Obstetrics and Gynecology, Philadelphia, Pennsylvania, 19104, United States
NCT01489319	Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS)	https://clinicaltrials.gov/study/NCT01489319	ELI-ROAS	TERMINATED	DRUG: Salsalate\|DRUG: Salsalate	Indiana University		47	INTERVENTIONAL	Indiana University Hospital, Indianapolis, Indiana, 46202, United States
NCT00344851	Exenatide and Metformin Therapy in Overweight Women With PCOS	https://clinicaltrials.gov/study/NCT00344851		COMPLETED	DRUG: metformin, exenatide or combined (metformin & exenatide )	Metabolic Center of Louisiana Research Foundation	Amylin Pharmaceuticals, LLC.	60	INTERVENTIONAL	Facility: Metabolic Center of Louisiana Research Foundation, Baton Rouge, Louisiana, 70808, United States
NCT02635386	EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)	https://clinicaltrials.gov/study/NCT02635386		COMPLETED	DRUG: Exenatide once weekly (EQW )\|DRUG: Dapagliflozin (DAPA)\|DRUG: EQW plus DAPA\|DRUG: Dapagliflozin plus Glucophage (MET ER)\|DRUG: Phentermine /Topiramate (PHEN/ TPM) ER	Woman's	AstraZeneca	119	INTERVENTIONAL	Woman's Hospital, Baton Rouge, Louisiana, 70817, United States
NCT00729560	Effects of Flutamide on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT00729560	PCOS	TERMINATED	DRUG: Flutamide\|DRUG: Placebo	Virginia Commonwealth University	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	8	INTERVENTIONAL	Virginia Commonwealth University General Clinical Research Center, Richmond, Virginia, 23298, United States
NCT01716429	Healthy Eating for Reproductive Health: Greenville	https://clinicaltrials.gov/study/NCT01716429	HER Health	WITHDRAWN	BEHAVIORAL: Vegan diet\|BEHAVIORAL: Low calorie diet	University of South Carolina	Prisma Health-Upstate	0	INTERVENTIONAL	Fertility Center of the Carolinas: Greenville Hospital System, Greenville, South Carolina, 29605, United States
NCT03229408	Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction	https://clinicaltrials.gov/study/NCT03229408	TIN-PCOS-AOD	RECRUITING	DRUG: Salsalate\|OTHER: Placebo	University of Illinois at Chicago	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	90	INTERVENTIONAL	Frank González, Chicago, Illinois, 60612, United States
NCT06049420	Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients	https://clinicaltrials.gov/study/NCT06049420		NOT_YET_RECRUITING	BEHAVIORAL: Lifestyle counseling and coaching	West Virginia School of Osteopathic Medicine		95	INTERVENTIONAL	West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia, 24901, United States
NCT01745471	Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL)	https://clinicaltrials.gov/study/NCT01745471	EIFFEL	ACTIVE_NOT_RECRUITING		AdventHealth Translational Research Institute	Sanford-Burnham Medical Research Institute\|Pennington Biomedical Research Center\|Boston University\|Tufts University	36	OBSERVATIONAL	Translational Research Institute for Metabolism and Diabetes, Orlando, Florida, 32804, United States
NCT03152591	Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT03152591	PCOS	COMPLETED	DRUG: LIK066\|DRUG: Placebo	Novartis Pharmaceuticals		29	INTERVENTIONAL	Novartis Investigative Site, Springfield, Missouri, 65802, United States\|Novartis Investigative Site, Philadelphia, Pennsylvania, 19104, United States\|Novartis Investigative Site, Berlin, 10117, Germany\|Novartis Investigative Site, Essen, 45147, Germany\|Novartis Investigative Site, Freiburg, 79106, Germany
NCT01150539	Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT01150539	POLY	COMPLETED	OTHER: 16-week exercise training program\|OTHER: Control Group without PCOS	Pennington Biomedical Research Center		8	INTERVENTIONAL	Pennington Biomedical Research Center, Baton Rouge, Louisiana, 70808, United States
NCT06124391	Novel Subtypes of Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT06124391		RECRUITING	OTHER: Long-term follow-up	Shandong University		50000	OBSERVATIONAL	Penn State College of Medicine, Hershey, Pennsylvania, 17033, United States\|Chengdu Jinjiang Maternity and Child Health Hospital, Chengdu, China\|Guangdong Second Provincial General Hospital, Guangzhou, China\|Shandong University, Jinan, 250012, China\|Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China\|Tianjin Medical University General Hospital, Tianjin, China\|General Hospital of Ningxia Medical University, Yinchuan, China\|Oulu University Hospital, Oulu, Finland\|National University Hospital, National University of Singapore, Singapore, Singapore\|Karolinska Institutet, Solna, 17165, Sweden\|Hacettepe University School of Medicine Hacettepe, Ankara, Turkey
NCT05950282	Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis	https://clinicaltrials.gov/study/NCT05950282		NOT_YET_RECRUITING		Lilli Health		1000	OBSERVATIONAL	Lilli Health, Houston, Texas, 77554, United States
NCT00364949	Intrauterine Environment in Polycystic Ovary Syndrome (PCOS) Probands	https://clinicaltrials.gov/study/NCT00364949		COMPLETED		Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)		70	OBSERVATIONAL	Northwestern University School of Medicine, Chicago, Illinois, 60611, United States
NCT04874415	Behavioral Economics for Activity Motivation in Adolescents (BEAM)	https://clinicaltrials.gov/study/NCT04874415		RECRUITING	BEHAVIORAL: 1RLD\|BEHAVIORAL: 1RLW\|BEHAVIORAL: 1RGD\|BEHAVIORAL: 1RGW\|BEHAVIORAL: 2RLD\|BEHAVIORAL: 2RLW\|BEHAVIORAL: 2RGD\|BEHAVIORAL: 2RGW\|BEHAVIORAL: 1FLD\|BEHAVIORAL: 1FLW\|BEHAVIORAL: 1FGD\|BEHAVIORAL: 1FGW\|BEHAVIORAL: 2FLD\|BEHAVIORAL: 2FLW\|BEHAVIORAL: 2FGD\|BEHAVIORAL: 2FGW	University of Pittsburgh	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	75	INTERVENTIONAL	UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15224, United States
NCT01840618	Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents	https://clinicaltrials.gov/study/NCT01840618		COMPLETED	DEVICE: Nasal Continuous positive airway pressure (CPAP)	Albert Einstein College of Medicine		50	OBSERVATIONAL	Children's Hospital at Montefiore, Bronx, New York, 10467, United States
NCT03041129	Post-Prandial Liver Glucose Metabolism in PCOS	https://clinicaltrials.gov/study/NCT03041129	PLUM	COMPLETED	DIAGNOSTIC_TEST: oral glucose tolerance test\|DIAGNOSTIC_TEST: MRI of liver	University of Colorado, Denver		19	OBSERVATIONAL	University of Colorado Anshutz Medical Campus/Children's Hospital Colorado, Aurora, Colorado, 80045, United States
NCT01421810	Ovarian Contribution to Androgen Production in Adolescent Girls	https://clinicaltrials.gov/study/NCT01421810	CBS001	ACTIVE_NOT_RECRUITING	DRUG: Dexamethasone\|DRUG: rhCG	University of Virginia	University of California, San Diego	80	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT01422746	Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess	https://clinicaltrials.gov/study/NCT01422746		RECRUITING	DRUG: Metformin	University of Virginia		20	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT00907153	Vitamin D for the Treatment of Women With Polycystic Ovary Syndrome (PCOS)	https://clinicaltrials.gov/study/NCT00907153		COMPLETED	DIETARY_SUPPLEMENT: Vitamin D\|DRUG: Placebo	Milton S. Hershey Medical Center		36	INTERVENTIONAL	Penn State College of Medicine, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, 17033, United States
NCT03677362	Weight Loss Intervention in Women With PCOS	https://clinicaltrials.gov/study/NCT03677362		COMPLETED	BEHAVIORAL: Weight loss intervention	University of Kansas Medical Center		12	INTERVENTIONAL	University of Kansas Medical Center, Kansas City, Kansas, 66160, United States
NCT03049462	The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists	https://clinicaltrials.gov/study/NCT03049462		RECRUITING	DRUG: Mirabegron\|OTHER: B Complex Plus Vitamin C Tablets	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)		100	INTERVENTIONAL	National Institutes of Health Clinical Center, Bethesda, Maryland, 20892, United States
NCT01028989	A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)	https://clinicaltrials.gov/study/NCT01028989		COMPLETED	DIETARY_SUPPLEMENT: Reduced Glycemic Load Diet\|DIETARY_SUPPLEMENT: Standard Diet	University of Alabama at Birmingham	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	23	INTERVENTIONAL	University of Alabama at Birmingham, Birmingham, Alabama, 35294, United States
NCT01927432	Ultrasound Characterization of Ovarian Follicle Dynamics in Women With Amenorrhea	https://clinicaltrials.gov/study/NCT01927432		ACTIVE_NOT_RECRUITING		Cornell University		80	OBSERVATIONAL	Human Metabolic Research Unit, Cornell University, Ithaca, New York, 14853, United States
NCT01360996	Low Dose OC Therapy in Women With Polycystic Ovary Syndrome (PCOS): Impact of BMI on Hyperandrogenism	https://clinicaltrials.gov/study/NCT01360996	BEYAZ-PCOS	COMPLETED	DRUG: 3 mg DRSP/20 μg EE	Woman's	Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma	64	INTERVENTIONAL	Woman's Hospital, Baton Rouge, Louisiana, 70815, United States
NCT00203996	Polycystic Ovary Syndrome (PCOS) and Sleep Apnea	https://clinicaltrials.gov/study/NCT00203996		TERMINATED	DEVICE: continuous positive airway pressure (CPAP)\|DRUG: depot leuprolide plus estrogen/progestin replacement\|DRUG: pioglitazone\|PROCEDURE: REM frag\|PROCEDURE: SWS supp	University of Chicago	National Institutes of Health (NIH)\|National Heart, Lung, and Blood Institute (NHLBI)	37	INTERVENTIONAL	University of Chicago, Chicago, Illinois, 60637, United States
NCT04068896	Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy	https://clinicaltrials.gov/study/NCT04068896		ACTIVE_NOT_RECRUITING	BIOLOGICAL: NGM120\|BIOLOGICAL: NGM120\|BIOLOGICAL: NGM120\|BIOLOGICAL: NGM120\|BIOLOGICAL: NGM120\|BIOLOGICAL: NGM120\|OTHER: Placebo	NGM Biopharmaceuticals, Inc		75	INTERVENTIONAL	NGM Clinical Study Site, Tucson, Arizona, 85719, United States\|NGM Clinical Study Site, Los Angeles, California, 90048, United States\|NGM Clinical Study Site, Los Angeles, California, 90084, United States\|NGM Clinical Study Site, Sacramento, California, 98517, United States\|NGM Clinical Study Site, San Diego, California, 92123, United States\|NGM Clinical Study Site, Santa Monica, California, 90404, United States\|NGM Clinical Study Site, Aurora, Colorado, 80045, United States\|NGM Clinical Study Site, Washington, District of Columbia, 20007, United States\|NGM Clinical Study Site, Miami, Florida, 33136, United States\|NGM Clinical Study Site, Chicago, Illinois, 60611, United States\|NGM Clinical Study Site, Baltimore, Maryland, 21201, United States\|NGM Clinical Study Site, Omaha, Nebraska, 68130, United States\|NGM Clinical Study Site, Charlotte, North Carolina, 28204, United States\|NGM Clinical Study Site, Cincinnati, Ohio, 45219, United States\|NGM Clinical Study Site, Philadelphia, Pennsylvania, 19111, United States\|NGM Clinical Study Site, Charleston, South Carolina, 29425, United States\|NGM Clinical Study Site, Myrtle Beach, South Carolina, 29572, United States\|NGM Clinical Study Site, Nashville, Tennessee, 37203, United States\|NGM Clinical Study Site, Dallas, Texas, 75390, United States\|NGM Clinical Study Site, Houston, Texas, 77030, United States\|NGM Clinical Study Site, Seattle, Washington, 98101, United States\|NGM Clinical Study Site, Milwaukee, Wisconsin, 53226, United States
NCT01899001	Mood and Nutrition Interventions in Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT01899001	MANI-PCOS	COMPLETED	BEHAVIORAL: Cognitive Behavioral Therapy\|BEHAVIORAL: Nutrition Counseling	University of Pennsylvania		40	INTERVENTIONAL	Penn PCOS Center, Philadelphia, Pennsylvania, 19104, United States
NCT03547453	Ovarian Ultrasonography for the Clinical Evaluation of Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT03547453		COMPLETED		Cornell University	University of Rochester	240	OBSERVATIONAL	Strong Fertility Center, Rochester, New York, 14623, United States
NCT03644524	Heat Therapy and Cardiometabolic Health in Obese Women	https://clinicaltrials.gov/study/NCT03644524	CMH	COMPLETED	BEHAVIORAL: Heat therapy	University of Oregon	American Heart Association	20	INTERVENTIONAL	University of Oregon, Eugene, Oregon, 97403, United States
NCT00518635	Low Dose Growth Hormone in Obese PCOS Women	https://clinicaltrials.gov/study/NCT00518635		WITHDRAWN	DRUG: Nutropin	Oregon Health and Science University		0	INTERVENTIONAL	Oregon Health and Science University, Portland, Oregon, 97239, United States
NCT03717935	Oral Amino Acid Nutrition to Improve Glucose Excursions in PCOS	https://clinicaltrials.gov/study/NCT03717935	ORANGE	COMPLETED	DIETARY_SUPPLEMENT: Essential Amino Acid (EAA) Supplement\|OTHER: Placebo	University of Colorado, Denver		27	INTERVENTIONAL	University of Colorado, Anschutz Medical Campus, Aurora, Colorado, 80045, United States
NCT00868140	Effects of Pioglitazone on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome (PCOS)	https://clinicaltrials.gov/study/NCT00868140	PCOS	TERMINATED	DRUG: pioglitazone\|DRUG: Placebo	Virginia Commonwealth University		51	INTERVENTIONAL	Virginia Commonwealth University General Clinical Research Center, Richmond, Virginia, 23298, United States\|Hospital de Clinical Caracas, Caracas, 1071, Venezuela
NCT01464398	Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)	https://clinicaltrials.gov/study/NCT01464398		COMPLETED	BEHAVIORAL: Stress reduction\|BEHAVIORAL: Stress reduction with Health education	Milton S. Hershey Medical Center	National Center for Complementary and Integrative Health (NCCIH)\|Thomas Jefferson University	86	INTERVENTIONAL	Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033, United States
NCT00640224	Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study	https://clinicaltrials.gov/study/NCT00640224		COMPLETED	DRUG: rosiglitazone\|DRUG: drospirenone/ethinyl estradiol	Silva Arslanian	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	65	INTERVENTIONAL	Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15224, United States
NCT02122380	The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome	https://clinicaltrials.gov/study/NCT02122380		COMPLETED	DRUG: Sitagliptin\|DRUG: Placebo	Vanderbilt University	National Heart, Lung, and Blood Institute (NHLBI)	23	INTERVENTIONAL	Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States
NCT05629858	Time Restricted Eating for the Treatment of PCOS	https://clinicaltrials.gov/study/NCT05629858		ENROLLING_BY_INVITATION	OTHER: 6-h Time restricted eating (TRE)\|OTHER: Calorie restriction (CR)\|OTHER: Control	University of Illinois at Chicago		300	INTERVENTIONAL	University of Illinois Chicago, Chicago, Illinois, 60612, United States
NCT01422096	Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess	https://clinicaltrials.gov/study/NCT01422096		WITHDRAWN	DRUG: Leuprolide	University of Virginia		0	INTERVENTIONAL	University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT02105428	Potential Impact of Polycystic Ovarian Syndrome on Protein Modifications and Accumulation	https://clinicaltrials.gov/study/NCT02105428		COMPLETED	BEHAVIORAL: Aerobic Exercise Training	Mayo Clinic		44	INTERVENTIONAL	Mayo Clinic, Rochester, Minnesota, 55905, United States
NCT02611128	Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia	https://clinicaltrials.gov/study/NCT02611128	DENND1A	SUSPENDED	OTHER: Phenotype/genotype assessment	University of Virginia	Penn State University\|Virginia Commonwealth University\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	65	OBSERVATIONAL	Center for Research in Reproduction, Charlottesville, Virginia, 22908, United States
NCT00683774	Insulin and Polycystic Ovary Syndrome	https://clinicaltrials.gov/study/NCT00683774		COMPLETED	DRUG: diazoxide	Virginia Commonwealth University	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	21	INTERVENTIONAL	General Clinical Research Center, Richmond, Virginia, 23298, United States
NCT02157974	Liver and Fat Regulation in Overweight Adolescent Girls	https://clinicaltrials.gov/study/NCT02157974	APPLE	COMPLETED	DRUG: Byetta 5Mcg Pen Injection	University of Colorado, Denver	National Center for Advancing Translational Sciences (NCATS)	92	INTERVENTIONAL	University of Colorado Anshutz Medical Campus/Children's Hospital Colorado, Aurora, Colorado, 80045, United States
NCT05721976	With Love, Grandma ("Con Cariño, Abuelita") Pilot Study	https://clinicaltrials.gov/study/NCT05721976		RECRUITING	BEHAVIORAL: With Love, Grandma ("Con Cariño, Abuelita")	University of Miami Sylvester Comprehensive Cancer Center	The V Foundation for Cancer Research	60	INTERVENTIONAL	University of Miami, Miami, Florida, 33136, United States