Bariatric Surgery
If you have been struggling with your weight, and diet and exercise have not yielded the desired results, there are a variety of options available to you, including bariatric surgery. Bariatric surgery may encompass a variety of procedures, which are collectively designed to help you lose weight. One common form of bariatric surgery is known as gastric bypass, which involves changing how your digestive system operates. Through these changes, your body may be better equipped to lose weight and maintain a healthier lifestyle. Bariatric surgery may also be recommended if you are experiencing health problems due to your weight. By speaking to your healthcare provider about the benefits and risks of these procedures, you can make a more informed decision about the best course of action for your personal health and wellness needs.
News

Opinion: Semaglutide is going off-patent in India. But will people who need it be able to get it?
Rules determining who gets access to semaglutide in India were written for different bodies with different cardiovascular risks.

GLP-1 Drugs Show Growing Promise for Afib Control
(MedPage Today) — For patients with obesity and atrial fibrillation (Afib), GLP-1 receptor agonist drugs may be the weight loss approach that better addresses their arrhythmia, observational data suggested.
People who came out of catheter ablation…

Hold GLP-1s Before Endoscopy? Clinical Trial Finds Retained Gastric Contents
(MedPage Today) — Patients on GLP-1 or GLP-1/GIP agonists had significant residual gastric volume (RGV) if the medication wasn’t held prior to upper endoscopy unless they were on a clear liquid diet the day before, the OCULUS randomized trial…

Unixell Biotech’s UX-GIP001 gains IND clearance for epilepsy
Shanghai Unixell Biotechnology Co. Ltd. has obtained IND clearance from the FDA for UX-GIP001, its iPSC-derived allogeneic cell therapy for focal epilepsy. A phase I study will evaluate UX-GIP001 in patients with drug-resistant epilepsy.

STAT+: Structure Therapeutics reports significant weight loss from mid-stage GLP-1 pill
An experimental obesity pill from Structure Therapeutics helped patients lose significant weight in a mid-stage trial, with a Phase 3 study in the works.

Structure Therapeutics reports more Phase 2 data for oral GLP-1
Structure Therapeutics has its much-anticipated oral GLP-1 data, and the results look to give the next-generation contender a chance against market incumbents Eli Lilly and Novo Nordisk.
The biotech said Monday …

Martha Stewart’s cardiologist says a simple smoothie add-in is like ‘taking Ozempic’
Martha Stewart says her cardiologist compared beetroot powder to “taking Ozempic” for weight loss. She now adds the supplement daily to her green juice.

What happens when patients stop taking GLP-1 drugs? New study reveals real world insights
As the use of injectable GLP-1 drugs continues to rise, questions persist about what happens after patients stop taking them in real-world settings. A new Cleveland Clinic analysis of nearly 8,000 patients suggests that discontinuing semaglutide and tirzepatide, on average, does not lead to significant weight regain in clinical practice, as many patients later restart the original medication or try an alternative obesity treatment.

‘Mormon Wives’ star weighs just 99 pounds at 5′ 10″, admits GLP-1 addiction
Layla Taylor reveals her eating disorder struggle on “Mormon Wives.” She weighs just 99 pounds at 5’10” and says she’s unable to stop destructive patterns.
Reviews
- Adams TD, Gress RE, Smith SC, Halverson RC, Simper SC, Rosamond WD, Lamonte MJ, Stroup AM, Hunt SC. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007 Aug 23;357(8):753-61. doi: 10.1056/NEJMoa066603. PMID: 17715409.
- Gloy VL, Briel M, Bhatt DL, Kashyap SR, Schauer PR, Mingrone G, Bucher HC, Nordmann AJ. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. BMJ. 2013 Oct 22;347:f5934. doi: 10.1136/bmj.f5934. PMID: 24149519; PMCID: PMC3806364.
- Courcoulas AP, Christian NJ, Belle SH, Berk PD, Flum DR, Garcia L, Horlick M, Kalarchian MA, King WC, Mitchell JE, Patterson EJ, Pender JR, Pomp A, Pories WJ, Thirlby RC, Yanovski SZ, Wolfe BM; Longitudinal Assessment of Bariatric Surgery (LABS) Consortium. Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA. 2013 Dec 11;310(22):2416-25. doi: 10.1001/jama.2013.280928. PMID: 24189773; PMCID: PMC3955952.
- Brito JP, Montori VM, Davis AM. Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations. JAMA. 2017 Feb 14;317(6):635-636. doi: 10.1001/jama.2016.20563. PMID: 28196240; PMCID: PMC5557277.
- Arterburn DE, Telem DA, Kushner RF, Courcoulas AP. Benefits and Risks of Bariatric Surgery in Adults: A Review. JAMA. 2020 Sep 1;324(9):879-887. doi: 10.1001/jama.2020.12567. PMID: 32870301.
References:
- Wikipedia Bariatric surgery. Accessed September 2023
- Agency for Healthcare Research and Quality. Accessed September 2023
- American Society for Metabolic and Bariatric Surgery. “Bariatric Surgery Procedures.” Accessed September 2023