Learn about Lipids
Lipids, a class of organic molecules, play a significant role in the sustenance of life. However, there is an inherent danger that lies in having excessive amounts of lipids in one’s body. The problem becomes especially pronounced when a person becomes overweight or obese, leading to a host of complications. Scientists have observed that hormones and changes take place in the body as a result of obesity, thereby discussing the significance of the study of lipids and their potential association with cancer. It’s worth noting that there exist various types of lipids, with some better than others. Therefore, oncologists must strive to acquire a thorough understanding of both fat and lipid metabolisms, particularly when dealing with an obese cancer patient. Our blog aims to provide an in-depth discussion of the aforementioned topics, highlighting their relevance in today’s world.
Videos:
Fats – Osmosis from Elsevier
Obesity: The little things – NIH
Scientific Journals:
1. Nature Reviews Endocrinology – Articles often delve deep into the molecular mechanisms behind obesity, including lipid metabolism.
2. Cell Metabolism – This journal publishes articles on metabolic pathways and often has articles specifically focused on lipids.
3. Journal of Lipid Research – A go-to journal specifically focused on lipids.
Online Databases:
1. PubMed – Offers a plethora of scientific articles and reviews. You can search using keywords like “lipid metabolism and obesity” to find relevant papers.
2. Google Scholar – Another resourceful platform to search scholarly articles and reviews.
Online Resources and Websites:
1. NCBI Bookshelf – Offers free book chapters and reviews on medical topics, including lipid metabolism.
– For instance, the book “Biochemistry of Lipids, Lipoproteins and Membranes” is available here.
2. World Health Organization (WHO)
Global Action Plan on Physical Activity 2018–2030: While not exclusively focused on obesity, this report discusses strategies to combat sedentary lifestyles, which are a significant risk factor for obesity and metabolic disorders. Link to Document
Global Status Report on Noncommunicable Diseases: This report includes a section on obesity and metabolic disorders as they relate to non-communicable diseases (NCDs). It provides global data and discusses preventive strategies. Link to Document
Obesity and Overweight Factsheet: Provides an overview of obesity, its global prevalence, and its impact on health, although it doesn’t delve into metabolic pathways like lipid metabolism. Link to Factsheet
Guideline: Sugars intake for adults and children: This WHO guideline provides recommendations about dietary sugars intake, which is highly relevant to obesity and metabolic disorders. Link to Guideline
Report of the Commission on Ending Childhood Obesity: This report provides a detailed look at childhood obesity and offers policy recommendations to tackle the issue. Link to Report
Reviews and Articles:
Frayn, K. N., Arner, P., & Yki-Järvinen, H. (2006). Fatty acid metabolism in adipose tissue, muscle and liver in health and disease. Essays in biochemistry, 42, 89-103. PubMed Link
Klop, B., Elte, J. W., & Cabezas, M. C. (2013). Dyslipidemia in obesity: mechanisms and potential targets. Nutrients, 5(4), 1218-1240. PubMed Link
Goldberg, I. J., Eckel, R. H., & Abumrad, N. A. (2009). Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways. Journal of lipid research, 50(Supplement), S86-S90. PubMed Link
Books:
“Biochemistry of Lipids, Lipoproteins, and Membranes” by Neale Ridgway and Roger McLeod. ScienceDirect. Amazon.
“Obesity: Epidemiology, Pathophysiology, and Prevention” by Debasis Bagchi and Harry G. Preuss. Routledge Press, Amazon.