Oncobesity News Posts
Alcohol Use and Antiobesity Medication Treatment
This cohort study examines the association of antiobesity medication use and alcohol use among participants enrolled in a weigh loss program.
Breast Cancer Incidence Still Rising Despite Decline in Death Rates
Despite the decline in death rates from breast cancer among women, the incidence of the disease has continued to rise in the US, by 1% a year from 2012 to 2021, according to an American Cancer Society analysis of data from the National Cancer Institute and the Centers for Disease Control and Prevention.
GLP-1 for Treating Obesity: 2024 Lasker-DeBakey Clinical Medical Research Award
In this Viewpoint, 2024 Lasker-DeBakey Clinical Medical Research Award winner Lotte Bjerre Knudsen describes her discovery of glucagon-like peptide-1 for the treatment of patients with obesity.
Biden will move to have Medicare, Medicaid cover GLP-1 weight-loss meds
The outgoing Biden administration will propose that pricey GLP-1 obesity medications such as semaglutide (Wegovy), and tirzepatide (Zepbound) be covered by Medicare and Medicaid.
Amgen says its Ozempic competitor helped patients lose 20% of their weight. Wall Street isn’t impressed
Amgen (AMGN) reported today the highly anticipated results of a mid-stage trial of its experimental weight loss drug and potential Ozempic competitor MariTide, however, Wall Street wasn’t very impressed.Read more…
Ozempic, Wegovy covered by Medicare and Medicaid under Biden admin proposal for anti-obesity GLP-1 drugs
The Biden administration is looking to expand access to anti-obesity GLP-1 drugs like Ozempic and Wegovy for people who have Medicare and Medicaid.
Biden wants to expand access to Ozempic and other popular weight loss drugs
President Joe Biden is trying to expand access to pricey blockbuster drugs in his final months in office.Read more…
Younger Breast Cancer Patients Face Higher Recurrence Risk
A retrospective study found that younger patients with ER-positive, ERBB2-negative breast cancer are more prone to late distant recurrence. Medscape Medical News
GLP-1 RA Drugs Benefit People With SLE, Lupus Nephritis
The glucose-lowering and weight-reducing drug class appears to benefit the heart and kidneys in people with lupus and lupus nephritis, independently of glucose-lowering and weight loss. Medscape Medical News
The Scan by 2 Minute Medicine®: Versatile Ozempic, Healthcare Reform, Unlocking the Brain, and Chickens and the Next Pandemic:
The Scan by 2 Minute Medicine® is a pop-culture medical newsletter and exclusive benefit for 2 Minute Medicine Plus subscribers. We begin with a discussion about Ozempic’s potential in treating alcohol use disorder. Then we take a closer look at how President-Elect Trump’s next term might affect healthcare.. After that, we examine a new therapy for
The post The Scan by 2 Minute Medicine®: Versatile Ozempic, Healthcare Reform, Unlocking the Brain, and Chickens and the Next Pandemic: first appeared on 2 Minute Medicine. Source: 2 Minute Medicine
Biden wants drugs like Wegovy, Ozempic covered by Medicare, Medicaid
Millions of Americans would be eligible to have popular weight-loss drugs like Wegovy or Ozempic covered by Medicare and Medicaid under a rule the Biden administration has proposed.
Medicare moves to expand coverage for weight-loss drugs Wegovy, Zepbound
The Biden administration is proposing a major expansion of how Medicare and Medicaid cover the weight-loss drugs Wegovy and Zepbound.
Inside the telehealth-fueled GLP-1 alternative market
How does the market for compounded GLP-1 drugs work? Let us explain.
West Virginia ends GLP-1 subsidy program, leaving many unable to afford the drugs
In 2020, West Virginia started a pilot program providing subsidies for GLP-1 weight loss drugs for state employees. It showed promising results, but the program ended in March, leaving many unable to afford the pricey drugs. Mark Strassmann has the story.
West Virginia ends promising subsidy program for GLP-1 weight loss drugs
In 2020, West Virginia launched a pilot program to subsidize GLP-1 drugs for public employees, but the program was shuttered in March.
Metabolic and bariatric surgery safe and effective for patients with severe obesity, study finds
A multicenter examination of data demonstrates that for patients with a body mass index at or above 70 kg/m2 metabolic and bariatric surgery is a potent intervention.
Exclusive-Thousands Turn to Wegovy Copies Each Month as FDA Considers Shortage Status
More than 200,000 prescriptions for copies of Novo Nordisk’s weight-loss drug Wegovy are getting filled by U.S. patients each month, an industry group told the U.S. drugs… Reuters Health Information
As many as 1 in 5 people won’t lose weight with GLP-1 drugs, experts say
About 20% of patients — as many as 1 in 5 — may not respond well to medications like Mounjaro and Wegovy, according to several obesity experts.
Scientists discover why breast cancer drug works better for some people
A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug. The finding, published in the journal mBio, suggests that in the future, doctors may use a simple test on a patient’s stool to check for certain bacteria in the gut that might help predict whether tamoxifen will work for them.
Taking a GLP-1 medication? Expert offers tips for holiday eating
So, you have managed to shed 30 pounds with the help of one of the new blockbuster GLP-1 drugs, but as the holidays near you worry about how to handle gatherings where decadent food will be served in abundance.
Stroke guidelines updated, with focus on women and GLP-1s
Women, especially those who had high blood pressure during pregnancy or entered menopause before age 45, are among those with a greater risk for stroke.
More than half of US adults could benefit from GLP-1 medications, researchers find
In a new analysis of national data, researchers at the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) estimated that 137 million U.S. adults, more than half of all adults, are eligible for semagludtide for weight loss, diabetes management, or prevention of recurrent cardiovascular events.
AI detects woman’s breast cancer after routine screening missed it: ‘Deeply grateful’
A U.K. woman had her breast cancer detected through AI after a routine mammogram came back as normal. Experts Drs. Nicole Saphier and Harvey Castro discuss the power of AI in cancer care.
Can RFK Jr. Limit Ozempic Access as HHS Chief? Here’s What to Know
President-elect Donald J. Trump is set to nominate Robert F. Kennedy Jr. to lead the Health and Human Services Department, where he would have limited power over drugs.
6 Natural Ozempic Alternatives That Can Help Quiet ‘Food Noise’
Several healthy habits can help you naturally manage hunger and quiet “food noise” without medication. FG Trade Latin/Getty Images
“Food noise” is not a clinical term but generally refers to constant thoughts about food.
Health experts say there are several ways people can naturally control their feelings of hunger and turn down “food noise” without medication.
They include eating high fiber and high protein foods, getting regular exercise and quality sleep, reducing stress, and avoiding extremely restrictive diets.
GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound have skyrocketed in popularity due to their ability to help people lose significant weight.
One reason these drugs are effective is that they help people reduce the amount of “food noise” they experience.
What is “food noise?”
“Food noise is when thoughts about food are constantly running through your head, even when you’re not hungry,” says Raj Dasgupta MD, a physician and chief medical advisor for Garage Gym Reviews. “It’s that nagging feeling that keeps drawing your attention back to snacks, meals, or cravings. Sometimes, it’s tied to stress or emotions, but it can also happen when your body’s hunger signals are out of balance.”
GLP-1 drugs like Ozempic can lower the volume of these signals.
“They make you feel fuller for longer, slow down how fast food leaves your stomach, and even reduce cravings by acting on parts of the brain that control appetite,” Dasgupta says. “Basically, they quiet the chatter about food, so it’s easier to focus on eating when you actually need to.”
Yet, the high cost and potential side effects can make taking a GLP-1 medication less desirable for many people.
However, there are several ways you can quiet “food noise” naturally without medication, including the following six simple lifestyle hacks recommended by health experts.
Avoid rigidity and extreme dieting
Food is more than fuel, but it does fuel the body. Not eating or severely restricting calories can have the opposite effect, causing people to consume excess calories.
Consuming small, frequent healthy meals and snacks throughout the day can help you manage hunger cues, says Becky Mehr MS, RDN, CEDS-C, LDN, the director of outpatient nutrition for the Renfrew Center.
She recommends consuming various foods, including starches, proteins, and fats, and advises against swearing off things you love within moderation.
“When we try to avoid certain foods or tasks, we naturally continue to perseverate on the item much more so than when we have the food or start on the task,” she says. “So, if you want an apple, have an apple. If it’s a cookie you are craving, have a cookie. Honoring cravings also enhances satisfaction at meals from day to day and reduces binges.”
Rather than denying yourself any food, she noted that portion control is key.
Mehr says that intuitive eating — tuning into feelings of fullness and eating when you’re hungry — can be helpful.
A 2024 study suggested that women who followed intuitive eating patterns were more likely to stabilize their weight and display fewer disordered eating habits.
Dig into protein
GLP-1s keep people feeling fuller longer. However, some people may experience a similar switch with dietary changes, including adding more protein to their daily meals.
A 2022 review suggested that high protein diets could be an effective weight loss strategy.
“High-protein diets help manage weight and food noise as proteins keep you feeling full longer and curb cravings,” says Chris Mohr, PhD, RD, a fitness and nutrition advisor for Fortune Recommends.
Mohr says good ways to add more protein to your diet include:
Lean meats, like skinless chicken breast
Eggs
Beans
Nuts
Fill up on fiber
Fiber-rich foods naturally slow digestion.
“Fiber-rich foods reduce food noise by adding bulk to your meals without extra calories and slowing digestion, which helps control hunger,” Mohr says. “Incorporating vegetables, fruits, whole grains, and beans into your diet is beneficial for overall health, including weight management and reducing cravings.”
A small 2023 study of 72 people indicated a link between increasing dietary fiber and weight loss. It supported older research from 2019 on nearly 350 people with overweight or obesity that suggested that fiber intake was associated with weight loss and sticking to a calorie-restricted diet.
Embrace exercise
Suggesting exercise for health, including weight loss and maintenance, isn’t new. However, physical activity can also help control cravings and hunger, which is sometimes an overlooked benefit.
“Exercise can temporarily suppress your appetite by lowering hunger hormones and boosting the ones that make you feel full,” Dasgupta says. “It also helps with stress, which is often a big trigger for food cravings.”
A small 2024 study of 14 people suggested that vigorous exercise could reduce the hunger hormone ghrelin.
A 2023 report on current evidence pointed to data that exercise improved appetite sensitivity but said its long-term effects on hunger hormones remain uncertain.
Squash stress
A 2022 review suggested that stress can influence eating behavior, including consuming foods high in fat, sugar, and calories. The authors pointed to recent data that indicated that psychological distress and increased cortisol (stress) hormones could increase a person’s odds of developing abdominal fat, a hallmark of metabolic syndrome.
“[Managing stress] is a tough one,” Mehr says. “Stress shows up daily and sometimes out of the blue.”
The authors of the 2022 review suggested that mindfulness was one possible solution. Mehr agrees.
“Take some deep breaths,” she says. “Take a break for a few minutes. Take a mindful walk [and] listen to the sounds around you — birds, leaves, traffic.”
Sleep soundly
A 2022 narrative review suggests that insufficient sleep could contribute to weight management issues. The study’s authors linked reduced sleep quality and quantity sleep with more snacking, higher calorie consumption, and more snacking, especially on foods high in fat and carbohydrates.
The authors suggested a possible link between sleep and hormone dysregulation, which can change a person’s metabolic rate and affect weight loss.
“When you’re tired, your hunger hormones go haywire, making you crave more food,” Dasgupta says. “Aim for seven to nine hours of solid sleep, and try to wind down before bed with something relaxing.”
Mehr suggests implementing a routine before bed that includes:
Screen-free time (including not watching TV in bed)
Set bedtime
Setting the temperature to around 65 to 68 degrees
“These all to let your body know and recognize it’s time to go to bed,” Mehr says.
Takeaway
“Food noise” is not a medical diagnosis but is used in clinical and colloquial settings to describe constant thoughts about food.
GLP-1 medications like Ozempic can help lower food noise by slowing digestion and reducing cravings. However, not everyone wants to use GLP-1 medicines for various reasons, including costs, access, and side effects (primarily GI discomfort).
Health experts say there are several ways people can control feelings of hunger and turn down “food noise” naturally. They include eating high fiber and high protein foods, getting regular exercise and quality sleep, reducing stress, and avoiding extremely restrictive diets.
Is Contaminated Drinking Water Tied to HR+ Breast Cancer?
A natural experiment enabled the study of whether high levels of perfluoroalkyl substances were linked to the onset of hormone receptor-positive breast cancer. Medscape News UK
As GLP-1 Use Surges, Clinicians Weigh Benefits and Risks
GLP-1 RAs to assist with weight loss have exploded in popularity. Researchers are working to identify which patients will benefit from them and their associated risks. Medscape Medical News
Oura rings to track blood sugar, Vaccines vs RFK Jr., and Ozempic 2.0: Pharma news roundup
Oura smart rings will soon be able to help users track their blood sugar levels through a new partnership with Dexcom (DXCM), the maker of the U.S.’s first over-the-counter continuous glucose monitor. Read more…
Metabolic and bariatric surgery safe and effective for patients with severe obesity
A team of researchers led by Pennington Biomedical Research Center’s Dr. Florina Corpodean has confirmed through a data analysis that metabolic and bariatric surgery is largely safe and effective for patients who are experiencing severe obesity.
Hims & Hers closes up 10% as Lilly tirzepatide compounding dispute resolution delayed
Post Content This post first appeared on Healthcare Articles on Seeking Alpha Want to know more about it? Read More
How anti-obesity drugs are linked to food waste
Taking anti-obesity drugs has led some U.S. adults to throw away more food than they tossed before starting the medications, a new study has found.
Heterogeneity of Residual Disease After Neoadjuvant Systemic Therapy in Breast Cancer
This review analyzes the heterogeneity of residual disease after neoadjuvant systemic therapy in patients with breast cancer.
Radiation-Associated Secondary Cancer in Patients With Breast Cancer
This cohort study examines the risk of radiation-associated sarcoma in patients with breast cancer harboring germline TP53 variants.
Which Breast Cancer Patients Can Skip Postop Radiotherapy?
The POLAR genomic signature can help predict the patients with early breast cancer who may benefit from adjuvant radiotherapy and who may not. Medscape Medical News
In aggressive form of breast cancer, response to therapy may contribute to tumor regrowth, study finds
A recent study by a team of researchers at Vanderbilt University found that response to radiation therapy for triple negative breast cancer (TNBC)—one of the most aggressive forms of the disease—may contribute to tumor recurrence.
Weight-loss drug tirzepatide may lower heart failure deaths
A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows.
‘Watershed Moment’: Semaglutide Effective in MASH
The GLP-1 receptor agonist improved both histology and fibrosis in patients, with additional improvements in their liver enzymes, noninvasive fibrosis markers, and cardiometabolic measurements. Medscape Medical News
Side Effects of GLP-1 Drugs: What Doctors Should Know
Popular weight loss drugs have been linked to gastrointestinal, mental health, and vision problems, but the benefits appear to outweigh the risks. Medscape Medical News
Cancer-like mutations in healthy cells point to origins of breast cancer
Researchers have pinpointed what could be the early genetic origins of breast cancer — cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators analyzed the genomes of more than 48,000 individual breast cells from women without cancer, using novel techniques for decoding the genes of single cells. While the vast majority of cells appeared normal, nearly all of the women harbored a small number of breast cells — about 3 per cent — that carried genetic alterations commonly associated with cancer. The findings suggest that these rare genetic anomalies may represent some of the earliest steps in a series of events that could culminate in breast cancer development.
Healthy women have cells that resemble breast cancer
A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods. The study discovered that at least 3% of normal cells from breast tissue in 49 healthy women contain a gain or loss of chromosomes, a condition known as aneuploidy, and that they expand and accumulate with age.