Oncobesity News Posts

STAT+: Pharmalittle: We’re reading about a U.S. rule on Chinese deals, Belgium refusing Mounjaro coverage, and more
Friday, October 23 – U.S. is poised to issue a proposed rule that would subject outbound licensing deals with Chinese biotech companies to additional scrutiny

STAT+: Telehealth leapfrogs FDA approval with off-label GLP-1 prescriptions for addiction
Friday, October 23 – As telehealth promotes GLP-1s for addiction, experts worry about fragmented care, and exposing patients to unknown risks.

Ozempic plus hormone therapy may help boost weight loss at menopause
Thursday, October 22 – Ozempic plus hormone therapy may help boost weight loss at menopause.

AAO: Sequential nonarteritic anterior ischemic optic neuropathy occurs earlier with GLP-1 receptor agonist exposure
Thursday, October 22 – For patients with nonarteritic anterior ischemic optic neuropathy (NAION), glucagon-like peptide-1 (GLP-1) receptor agonist exposure is associated with earlier sequential NAION, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held Oct. 9 to 12 in New Orleans.

AAO: Association between GLP-1 receptor agonists and age-related macular degeneration explored
Thursday, October 22 – Crude odds ratios suggest an increased risk for age-related macular degeneration (AMD) in association with glucagon-like peptide-1 receptor agonist (GLP-1 RA) use, but this finding is reversed after adjustment for cardiometabolic confounding variables, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held Oct. 9 to 12 in New Orleans.

Ultrasounds for Schizophrenia; ‘Circadian’ Depression; GLP-1s and Eating Disorders
Thursday, October 22 – (MedPage Today) — A single, 10-minute transcranial ultrasound session led to a modest but significant drop in delusion scores among people with schizophrenia in a sham-controlled pilot trial. (npj Acoustics)
President Trump announced that the…

Started a GLP‑1 drug like Ozempic or Mounjaro? Here’s what you need to know about nutrition
Thursday, October 22 – Around half a million Australians use GLP-1 medications for diabetes—and when you add people who use them for obesity and weight-related conditions, the total is much higher.

Another Incretin Drug Proves Mettle in Sleep Apnea
Thursday, October 22 – (MedPage Today) — Treatment with the novel triple agonist retatrutide improved obstructive sleep apnea (OSA) in adults with obesity or overweight regardless of type 2 diabetes, two parallel randomized clinical trials showed.
Mean reduction in…

Novo’s CagriSema achieves 25% weight loss in women, driven by younger patients
Wednesday, October 21 – Post hoc analyses in women divided by menopausal status show how Novo’s next-generation GLP-1 drug affects key cohorts of patients.

1 in 4 Army Men Have Low T; GLP-1 in Menopause; Retatrutide Side Effects on Reddit
Wednesday, October 21 – (MedPage Today) — Roughly a quarter of active-duty U.S. Army men had a single morning testosterone concentration under 300 ng/dL, a commonly used cutoff for low testosterone. (JAMA)
Nearly half of American women ages 40 to 60 reported menopausal…

Hormone therapy may increase weight-loss effectiveness of GLP-1s
Wednesday, October 21 – The success stories of GLP-1 weight-loss medications are dominating the airwaves. Midlife women, who commonly experience weight gain resulting from menopause, have been especially drawn to the drugs.

GLP-1 drugs linked to lower kidney failure risk in bipolar disorder
Tuesday, October 20 – Mayo Clinic researchers found that GLP-1 receptor agonists, medications widely used for diabetes and weight management, were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease.

Should amylin have been obesity therapeutics’ primary target from the start?
Tuesday, October 20 – While GLP-1 medicines have become synonymous with weight loss, at least one expert thinks amylin would have been the go-to target if biopharma had been focused on the blockbuster indication 10 years ago. A new wave of therapies is now exploring this potentially gentler mechanism.

GLP-1 drugs linked to lower risk of serious heart-related complications and infections after surgery
Monday, October 19 – GLP-1 medications, widely prescribed for diabetes and weight loss, may also help protect people from serious complications after surgery. People taking GLP-1 medications had lower rates of major heart-related complications and infections after surgery than those not taking the drugs, according to results of a study of more than 2 million adults undergoing surgery presented at the ANESTHESIOLOGY 2026 annual meeting.

Engineers use AI, Reddit to identify potential side effects of unapproved new GLP-1
Saturday, October 17 – Retatrutide, a next-generation GLP-1 weight-loss drug, is not yet approved for use. Nevertheless, online forums reveal that people are purchasing unapproved versions of the drug, which are not intended for human consumption, and sharing their experiences.

Schizophrenia and type 2 diabetes are linked, but GLP-1s could help manage the risks
Friday, October 16 – Treatment with glucagon-like peptide-1 receptor agonists (GLP-1s) was associated with lower risks of psychiatric hospitalization and psychiatric emergency department visits in people with both schizophrenia and type 2 diabetes (T2D), compared with no GLP-1 treatment or treatment with newer diabetes medications, according to new research published in The Lancet Psychiatry.

Ozempic and Wegovy linked to rare risk of sudden vision loss
Friday, October 16 – Popular diabetes and weight loss drugs such as Ozempic and Wegovy have been linked to a slightly increased risk of a rare condition that can cause sudden, potentially permanent vision loss. Although the risk remains very low, Rutgers researchers say the findings warrant attention as millions of people turn to GLP-1 medications.

Trial finds 2 strategies to maintain weight loss results after stopping GLP-1s
Thursday, October 15 – Trial finds 2 strategies to maintain weight loss results after stopping GLP-1s.

Verdiva ends mid-stage study of oral GLP-1 amid ‘market evolution’
Thursday, October 15 – The candidate is an oral version of ecnoglutide, a subcutaneous formulation of which is approved in China for type 2 diabetes and weight management. Pfizer owns commercialization rights for ecnoglutide in the Asian country.

New study examines GLP-1 impact on interactions with criminal justice system, employment, housing stability
Thursday, October 15 – A wave of clinical trials have begun to test the ability of GLP-1 weight loss drugs to quell various substance use disorders, with some promising results. A new trial announced…

These Are The Most Common GLP-1 Side Effects — And What Doctors Say You Need For Relief
Thursday, October 15 – Doctors suggest digestive aids, protein supplements, skin care and more.

Orforglipron shows weight loss benefits for both menopause and type 2 diabetes
Wednesday, October 14 – Orforglipron shows weight loss benefits for both menopause and type 2 diabetes

Bootleg Retatrutide Deaths? PMOS and Dementia; Weight-Loss Drug to Be Discontinued
Thursday, October 15 – (MedPage Today) — Two recent deaths tied to counterfeit versions of retatrutide, an investigational weight-loss medication, were reported to the FDA. (CBS News)
Meanwhile, ongoing lawsuits allege that GLP-1 receptor agonists can cause severe…

No Effect of GLP-1s on Anti-VEGF Injection Frequency for Diabetic Macular Edema
Wednesday, October 14 – (MedPage Today) — NEW ORLEANS — GLP-1 receptor agonists did not significantly affect anti-VEGF treatment frequency in patients with diabetic macular edema (DME), a large retrospective cohort study showed.
Over 24 months of follow-up, “no sustained…

Verdiva cans mid-stage obesity trial of GLP-1 pill, citing ‘market evolution’
Wednesday, October 14 – Verdiva Bio, one of the best-funded private biotechs seeking to get into the lucrative obesity drug market, has terminated one of the Phase 2 trials of its lead asset, a spokesperson …

Triple-action drug retatrutide delivers major weight loss for people with diabetes, Phase III trial finds
Wednesday, October 14 – A recent Phase III clinical trial, TRIUMPH-2, evaluated the efficacy and safety of retatrutide, a triple receptor agonist and experimental once-weekly injection being developed to treat obesity and type 2 diabetes. What sets it apart from drugs such as semaglutide (Wegovy), which targets one hormone, and tirzepatide (Zepbound), which targets two, is its ability to activate three hormone receptors at once.

Wellness Apps, Medically Tailored Meals Help Slow Weight Gain After GLP-1s
Sunday, October 11 – Recent research shows that structured support may help with weight maintenance after stopping GLP-1s. licensed miniseries · E+/Getty
Most people regain a significant portion of the weight they lost within 1 year of stopping GLP-1 medications such as semaglutide (Wegovy) or tirzepatide (Zepbound).
A small study found that structured support, including a digital weight management app or medically tailored meals, may help slow weight regain after stopping GLP-1 medications.

HHS’ need for R&D speed; weird GLP-1 side effects
Saturday, October 10 – HHS is cranking up its efforts to accelerate drug development; more reports are emerging about off target effects of obesity drugs.

FDA takes aim at misleading online claims for compounded GLP-1 drugs
Saturday, July 4 – On June 16, 2026, the US Food and Drug Administration (FDA) issued 25 warning letters to various telehealth companies alleging that their websites contained false or misleading claims about compounded semaglutide, tirzepatide, and, in one case, liraglutide products….By: McDermott Will & Schulte

Semaglutide for Weight Loss Without Diabetes: What the Approval Covers, What Programs Skip, and What Results Actually Look Like
Tuesday, May 19 – Semaglutide for Weight Loss Without Diabetes: What the Approval Covers, What Programs Skip, and What Results Actually Look Like