The Obesity-Drug Revolution Is Stalling

For most of my adult life, I’ve felt helpless about being overweight. When I met with a doctor a few years ago to discuss my high cholesterol, he held up a hunk of faux flesh meant to model a pound of excess fat and encouraged me to lose 20 of said gelatinous blobs. Perhaps, he […]
Lilly keeps up legal fight against GLP-1 compounders

Despite recent setbacks in court, Eli Lilly is doubling down on its fight against compounded weight loss drugs. The pharma giant told Endpoints News on Tuesday that it plans to refile its complaint against the …
Obesity Rate Declining in U.S. (Gallup)

Gallup: Obesity Rate Declining in U.S. — Use of GLP-1 injectables for weight loss has more than doubled since early 2024 — WASHINGTON, D.C. — After peaking at a record high of 39.9% in 2022, the U.S. adult obesity rate has gradually declined to 37.0% in 2025.
Obesity Drops in Adults; Wegovy’s Heart Protection; Women Turn to Testosterone

(MedPage Today) — The obesity rate for adults in the U.S. dropped to 37% in 2025 after peaking at 39.9% in 2022, but diabetes has reached an all-time high, at 13.8%, according to a Gallup survey. Over a 10-year span, GLP-1 receptor agonists weren…
Researchers Edited Mouse Genes To Force Their Liver To Produce Its Own GLP-1 Drugs… And It Worked For 28 Weeks

Shutterstock Modern medicine can do some amazing things, and has saved the lives of countless millions of people. There are, however, some drawbacks to most medications. For one, it can be very expensive. Another issue is that some of them are difficult to develop, resulting in occasional shortages. Finally, the medication is generic in the […]
Texas Is Suing Tylenol Makers Over Claims of Links to Autism. Here’s Everything to Know About the Lawsuit

Texas Attorney General Ken Paxton is suing the pharmaceutical companies behind Tylenol for “deceptively marketing” the medication as a safe option for pregnant mothers. The lawsuit against Johnson & Johnson and Kenvue, which Paxton filed on Tuesday, claimed that the companies knew that being exposed to acetaminophen, the active ingredient in Tylenol, before birth or […]
More than a third of Lilly’s new Zepbound prescriptions are coming from DTC

The impact of pharma’s direct-to-patient efforts is getting clearer. When Lilly launched its LillyDirect program in January 2024, it wasn’t immediately clear how big the business would be. And for a while …
Weight Loss Drugs May Also Curb Substance Use Disorders

Research has suggested the potential of GLP-1 medications for treating substance use disorders, including alcohol, opioids, nicotine, and psychostimulants.
STAT+: Pharmalittle: We’re reading about rising GLP-1 use, a psychedelic therapy for depression, and more

Rise and shine, everyone, another busy day is on the way. And it is getting off to a good start here on the Pharmalot campus, where we have cool breezes and clear blue skies greeting us today. Who could ask for anything more? Actually, we could — it is time to reheat the coffee kettle for […]
How Skin-Care Brand Fitish is Making Prescription GLP-1 Meds Part of Its Business Model

Despite the growing ubiquity of GLP-1 (glucagon-like peptide-1) medication use, there is still quite a bit of confusion, stigma and misinformation surrounding injections like Ozempic. There’s also a major lack of access for many patients who stand to benefit from the meds; Fitish founder Jenna … Continue reading