January 28, 2026

For a lot of us, when we hear that consumer confidence, our confidence, has fallen to its lowest level since 2014, it is not some abstract statistic. It is a reflection of what so many of us are already feeling in real time. Groceries still cost too much, gas prices keep biting into the budget, […]

HHS outlines path for lower-cost drugs via direct sales

The Department of Health and Human Services issued a special advisory bulletin clarifying that pharmaceutical manufacturers may sell lower-cost prescription drugs directly to Medicare and Medicaid patients without violating the Anti-Kickback Statute, provided that specific safeguards are met. The guidance, issued by HHS’ Office of Inspector General on Jan. 27, outlines criteria that “lower the […]

Roche Reports Upbeat Efficacy Data From Phase II Obesity Study

Roche Holding AG RHHBY announced positive top-line data from a mid-stage study of its investigational candidate, CT-388, being developed for the treatment of obesity. CT-388 is a once-weekly injectable dual GLP-1/GIP RA, designed to curb appetite and improve blood-sugar control by targeting key metabolic pathways. Roche’s phase II dose-finding study evaluated CT-388’s efficacy and safety across […]

Nearly Half of U.S. Adults Will Have Obesity by 2035. What Can Be Done?

Obesity rates in the U.S. are projected to rise over the next decade, but lifestyle strategies that may help reverse the trend. Robert DEYRAIL/Gamma-Rapho via Getty Images Researchers predict that the obesity rate among U.S. adults will rise to 47% of the population by 2035. They say the increases will be particularly significant among certain […]

When Hunger Goes Quiet

For Dr Kesava Reddy Mannur, Clinical Director of Metabolic & Bariatric Surgery, the change he sees in patients taking GLP-1 drugs is unmistakable. “They aren’t just eating less,” he says. “They’re thinking about food differently. Patients describe a hush where a constant internal tug once lived. The mental chatter around eating—now widely called food noise—begins […]

STAT+: Eli Lilly expands work on gene therapies for hearing 

Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. We have a lot of news this morning that we’ll get straight into. Regenxbio trials halted after brain tumor found in patient The FDA paused trials for two experimental gene therapies from Regenxbio […]