Orforglipron Helps Maintain Weight Loss After Injectables
Topline results from the ATTAIN-MAINTAIN trial show that orforglipron, an investigational oral GLP-1 RA, helps people maintain weight loss after switching from an injectable. Medscape Medical News
My current supplement stack
Two years ago, I was 60lbs heavier, had high blood pressure, insomnia, brain fog, IBS and in constant osteo arthritic pain, suffering from frequent Lupus flares. I couldn’t handle light to moderate exercise without being bedridden for days afterwards. A brave medical professional told me that I need to get healthy and lose weight, and […]
Eli Lilly is eyeing an off-ramp for patients to switch from weight loss injections to pills
Although the injectable forms of the popular GLP-1 drugs are more effective, the pills under development are both easier to take and will be cheaper
Can Medifast Overcome GLP-1 Pressure With Its Growth Strategy?
Medifast, Inc. MED recognizes that the weight-loss and wellness landscape has evolved quickly as GLP-1 drugs gain wider adoption, reshaping how obesity and health are viewed by offering an effective way to suppress appetite and lose weight. While powerful, GLP-1 therapies are not enough for long-term health, as most weight-related challenges come from poor metabolic […]
Can you get addicted to a GLP-1?
Model Brooks Nader calls these drugs a “crutch.”
Chipotle Is Launching A New Menu Item With Up To 81 Grams Of Protein
Chipotle is rolling out a brand-new menu. Beginning Tuesday, December 23, customers in the U.S. and Canada will be able to order from the chain’s first-ever High-Protein Menu that’s loaded with six never-before-seen meal combos, including a delicious and filling High Protein Cup – Chipotle’s debut snack option. The launch coordinates with a trend towards […]
Novo Nordisk (NVO) Fell Following a Profit Warning Release
Parnassus Investments, an investment management firm, released its “Parnassus Value Equity Fund” third-quarter 2025 investor letter. A copy of the letter can be downloaded here. The fund focuses on owning a concentrated portfolio of U.S. large-cap stocks. For the third quarter of 2025, the fund reported a net return of 7.46% outperforming its benchmark, the […]
Neovascular Age-Related Macular Degeneration and GLP-1 RAs—Reply
In Reply We read the letters with great interest commenting on our recent article. We agree that surveillance bias is a concern in observational studies using administrative data. To mitigate this, we implemented several methodological approaches. First, we used duration of diabetes as a covariate in propensity score matching, which serves as a proxy for […]
Neovascular Age-Related Macular Degeneration and GLP-1 RAs
To the Editor We read with interest the study by Shor et al showing a 2-fold relative risk of newly diagnosed neovascular age-related macular degeneration (nAMD) among patients with type 2 diabetes prescribed glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment. Over a mean follow-up period of 2.4 years, the absolute risk of receiving a new […]
Rise of Direct-to-Patient GLP-1 Sales Shakes Up Care Models, HCPs Split on Pharma’s Expanding Role
NEW YORK–(BUSINESS WIRE)–The 43rd Barometer from Sermo, a fast, frictionless HCP social engagement platform and leader in healthcare insights, shows that pharma-led direct-to-patient (DTP) GLP-1 prescribing programs are transforming treatment access pathways. Yet findings from 953 surveyed GLP-1 prescribers reveal sharp divisions over how involved pharma should be in clinical evaluation and prescribing. DTP Models […]