Taking the next shot: GLP-1 research and the new era of weight loss

Soaring in popularity, GLP-1 medications—from weekly injections to newly available pills—are rapidly reshaping how Americans think about weight loss. In fact, a recent poll finds 1 in 8 adults are now taking medications like Ozempic or Wegovy for weight loss or chronic conditions, and use is expected to keep rising.

Bariatric surgery programs face upheaval amid growing GLP-1 use for weight loss

At Roxborough Memorial Hospital in Philadelphia, surgeon Piotr Krecioch has his hands full launching a program offering surgical interventions to treat obesity. One in three Philadelphians are living with obesity, putting them at higher risk of chronic conditions like diabetes and heart disease, but these days fewer are seeking the bariatric surgical procedures long considered a leading medical treatment for the condition.

Despite Side Effects, People Continue Taking Ozempic for Weight Loss

People who lose weight with GLP-1 drugs are likely to continue using the medication despite the side effects. Image Credit: geckophotos/Getty Images

A recent study found that many people using GLP-1 drugs for weight loss choose to continue the medication despite unpleasant side effects. 

The researchers found that in addition to weight loss, perceived reductions in appetite and cravings were the strongest predictors of satisfaction and intention to continue treatment with Ozempic. 

Obesity rates are rising, despite GLP-1s. What does it mean?

By 2030, nearly half of all American adults will have obesity, according to research published in the New England Journal of Medicine. In every single state, researchers expect at least 35% of adults to have a body mass index of 30 or higher, the threshold that defines obesity. That prediction may come as a shock, as weight loss medications like Wegovy and Zepbound become more popular and more affordable.