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GLP‐1 Receptor Agonists for the Prevention of New‐Onset Heart Failure: A Systematic Review and Meta‐Analysis of Placebo‐Controlled Randomized Clinical Trials

ABSTRACT Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP-1 RA prevent new-onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta-analysis of randomized placebo-controlled trials (RCT) of treatment with GLP-1 RA in participants without HF. The hazard […]

Healthcare, Vol. 13, Pages 3061: Analysis of Prediabetes in Veterans: Assessing Diagnosis and Population Characteristics Across a Region of Veterans Affairs Health Care Systems

Healthcare, Vol. 13, Pages 3061: Analysis of Prediabetes in Veterans: Assessing Diagnosis and Population Characteristics Across a Region of Veterans Affairs Health Care Systems Healthcare doi: 10.3390/healthcare13233061 Authors: Beth D. Greck Amanda T. Pons-Junkins Robert S. Colling Paula Richley Geigle Background/Objectives: Currently, 873,000 patients within the VA Health Administration potentially have prediabetes, based on HbA1c. […]

India’s pharmaceutical sector transition from generic to innovative drugs manufacturers, says CDSCO

NEW DELHI: India’s pharmaceutical sector is currently transitioning from a focus on generic drugs to the development of next-generation innovative biologics, as highlighted by the Central Drugs Standard Control Organization (CDSCO) of the Ministry of Health and Family Welfare, Government of India. This transition is driven by an innovation-focused ecosystem that emphasizes biosimilars, peptides, complex […]

The perfect thing to say if someone calls you fat

I still remember the first time I was introduced to the concept of “fat”. I was watching an aunt dissect a piece of fried chicken at dinner, using a knife and fork to peel off the skin to reveal the juicy, marbled white layer underneath. “So much fat,” she sighed, leaving it untouched at the […]

JPMorgan Raises Eli Lilly (LLY) Price Target to $1,150, Maintains Overweight Rating

Eli Lilly and Company (NYSE:LLY) is included among the 15 Best Stocks to Buy for Medium Term. Photo by Dan Dennis on Unsplash On‍ November 18, JPMorgan analyst Chris Scho‍tt r‌aised the firm‍’s‍ price ta‌rg​et on Eli Lilly and Company (NYSE:LLY) to $1,150 from $1,050 wh‍ile maintaining an Overw‍eig​ht ratin⁠g after meetings with management. JPMorgan […]

How obesity is driving Pakistan’s diabetes epidemic

Pakistan’s diabetes crisis is now among the worst in the world, but health experts warn that only half the battle is being fought. Obesity, a critical driver of Type 2 diabetes, remains largely overlooked for the main reason that people in Pakistan see it as a lifestyle failure, not a disease. The International Diabetes Federation […]

Postpartum Prescription of GLP-1 Drugs Has Increased Sharply, Study Finds – The New York Times

Postpartum Prescription of GLP-1 Drugs Has Increased Sharply, Study Finds  The New York Times The complicated relationship between GLP-1s and pregnancy  The Washington Post Study links GLP-1 use to some pregnancy risks — but the research has key caveats  Live Science New Moms’ GLP-1 Prescriptions Jumped After Wegovy Approval  MedPage Today People who stopped taking weight-loss drugs before or […]

There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests

The popularity of GLP-1 weight-loss medications continues to soar—and their uptake is helping to push down obesity rates on a national scale—but a safe, evidence-based way off the drugs isn’t yet in clear view. An analysis published this week in JAMA Internal Medicine found that most participants in a clinical trial who were assigned to […]