A weight loss pill that works like Ozempic? Early data on orforglipron sparks major buzz

A new oral GLP-1 receptor agonist, orforglipron, is revolutionizing weight management by offering a needle-free alternative to injectables. Clinical trials show significant weight loss and metabolic improvements, mirroring injectable efficacy. This convenient daily tablet promises better adherence and broader accessibility for individuals seeking effective obesity care, marking a significant shift in treatment delivery.

This 7% Yielder Could Be a Top AI Play

Key Points A looming patent cliff in which Pfizer will lose patent exclusivity to a handful of drugs has combined with cratering revenue from COVID-19 treatments to drive Pfizer shares down 50% since 2022. Pfizer has two important catalysts that can help it not only survive but also thrive amid these these challenges. Pfizer’s yield […]

Weight loss drugs go from niche to mainstream – Axios

Weight loss drugs go from niche to mainstream  Axios Ozempic and Other GLP-1s Are Now Being Marketed to People Who Aren’t Obese  Bloomberg.com Public health should embrace GLP-1 drugs without abandoning obesity prevention  statnews.com Is everyone around you microdosing Ozempic?  Vogue India What we still don’t know about weight-loss drugs  MIT Technology Review

Biomolecules, Vol. 15, Pages 1670: Incretin-Related Pathology and Serum Exosome Detection in Experimental Alcohol-Related Brain Damage

Biomolecules, Vol. 15, Pages 1670: Incretin-Related Pathology and Serum Exosome Detection in Experimental Alcohol-Related Brain Damage Biomolecules doi: 10.3390/biom15121670 Authors: Suzanne M. de la de la Monte Ming Tong Yiwen Yang Alcohol’s chronic neurotoxic and degenerative effects mediate alcohol-related brain damage (ARBD), which is marked by neurobehavioral, cognitive, and motor deficits. Major underlying abnormalities include […]

Why you need a GLP-1 exit plan

I’ve seen clients start GLP-1 medications full of hope, and stop them feeling betrayed by their own biology. Some reached their limit with side effects: relentless nausea, fatigue, or the quiet loss of joy in eating. Others simply couldn’t afford to stay on. A few never saw the promised results at all. But for nearly […]