When is it Worth Working?
Published on December 13, 2025 9:40 PM GMT tl;dr: How does an agent decide whether it is worth doing work to get something, as opposed to not working and not getting it? I’m a neuroscientist and my lab did an experiment to explore this question. Rats did voluntary work to earn water in a closed economy, […]
How Were GLP-1 Drugs and Bone Health Linked?
(MedPage Today) — You passed medical training, now see if you can pass our weekly quiz
Ultimate guide to beating Ozempic’s WORST side effect: Secret trick to avoid embarrassment… follow DR ROCIO’s seven-step plan
I’m a board-certified endocrinologist and , contrary to popular belief, choosing GLP-1 treatment isn’t the ‘ easy way out.’ It takes real work.
Stupid is as stupid does
Tags: glp1, ozemic, blind, funny 459 points, 157 comments.
“DPP- 4 inhibitor alleviates gut-brain axis Parkinsons disease pathology” – can dipeptidyl peptidase 4 inhibitors be repurposed as disease-modifying drugs for body-first Parkinsons disease patients?
In their manuscript, Jeong et al investigated the effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4is), in a rotenone-based mouse model of Parkinson’s disease (PD).1 The study explored the association between diabetes and PD, focusing on the potential therapeutic benefits of glucagon-like peptide-1 receptor (GLP-1-R) agonists,2 given that DPP-4is are hypoglycaemic agents that enhance the […]
Ozempic may offer a surprising bonus benefit for brain health
A new analysis suggests that people with type 2 diabetes who use GLP-1 medications like Ozempic, Trulicity or Victoza may be less likely to develop epilepsy than those taking DPP-4 inhibitors. Semaglutide showed the strongest connection to lowered risk. Researchers caution that the findings show an association, not proof of cause and effect. More rigorous […]
Destination XL Group, Inc. (NASDAQ:DXLG) Q3 2025 Earnings Call Transcript
Destination XL Group, Inc. (NASDAQ:DXLG) Q3 2025 Earnings Call Transcript December 12, 2025 Operator: Thank you for standing by and welcome to Destination XL Group’s Third Quarter Fiscal 2025 Earnings Conference Call. [Operator Instructions] I would now like to hand the call over to John Cooney, Chief Accounting Officer. Please go ahead. John Cooney: Thank […]
Amy Schumer Praised Chris Fischer’s Support Hours Before Announcing Split
Amy Schumer gave her now-estranged husband, Chris Fischer, a social media shout-out before announcing their separation. “Just found this from years ago pretty. My truest self. Chris dug it,” Schumer, 44, captioned a Friday, December 12, Instagram video from her 2021 endometriosis surgery. “I’ve been through a lot with endometriosis. Tell someone you love they […]
One GLP-1 Drug May Be Better Than Rivals for Glaucoma Risk
(MedPage Today) — Use of the dual GIP/GLP-1 drug tirzepatide (Mounjaro, Zepbound) was associated with a significantly reduced risk of glaucoma compared with GLP-1 drugs among patients with type 2 diabetes, a large retrospective cohort study suggested…
What to know about Cushing’s syndrome, which led to Amy Schumer’s dramatic weight loss
Comedian Amy Schumer, 44, has recently come clean about her struggle with Cushing’s syndrome, leading to a dramatic weight loss. Schumer’s transformation has sparked conversation online, to which she responded in a now-deleted Instagram post that shut down speculation about cosmetic enhancements. “I didn’t lose 30lbs — I lost 50,” she emphasized on social media, […]