2025 felt like a disaster — but the numbers tell a very different story

2025 is just about in the books, and the reviews are in: It sucked. Over at the subreddit r/decadeology, you can check out a long, long thread of redditors submitting reasons why 2025 was, in the words of the first post, “a long, disappointing year.” War in Gaza, vibecessions, chaos in the White House, growing […]

Life, Vol. 16, Pages 16: Diabetes Mellitus and Atrial Fibrillation: Mechanistic Insights and Therapeutic Impacts of Glucose-Lowering Drugs

Life, Vol. 16, Pages 16: Diabetes Mellitus and Atrial Fibrillation: Mechanistic Insights and Therapeutic Impacts of Glucose-Lowering Drugs Life doi: 10.3390/life16010016 Authors: Mihai Grigore Andreea-Maria Grigore Martin-Graur Ruxandra-Elena Verde Ioana Gabriela Uscoiu Camelia Nicolae Ana-Maria Balahura Adriana-Mihaela Ilieșiu Background/Objectives: Diabetes mellitus (DM) represents a major global public health challenge and is consistently associated with an […]

Why most health resolutions fail

As wellness advice floods social media, experts point to a short list of science-backed habits that improve health—and a few popular resolutions you’re better off skipping. Every January, millions of people resolve to improve their health. Many start with dramatic overhauls—cutting out entire food groups, committing to daily workouts, or vowing to reinvent their routines […]

Phosphodiesterase‐4 Inhibition as a Potential Therapeutic Strategy in the Management of Obesity: a Review

ABSTRACT Phosphodiesterase 4 (PDE4) inhibitors, originally developed for chronic inflammatory diseases, have shown unexpected metabolic benefits, including weight reduction and improved glycemic control in both preclinical and clinical studies. Weight loss typically occurs within the first 6–12 months of treatment and may be sustained over several years. While the underlying mechanisms remain incompletely understood, preclinical findings […]

Agrifoodtech in 2025: What broke, what bent—and what might still work

2025 was meant to be the year agrifoodtech found its footing again. Instead, it turned into something messier: a year of recalibration, retrenchment, and some very public reality checks. Funding fell further than many expected, high-profile companies stumbled or collapsed, and long-standing assumptions about consumer demand, climate narratives, and venture-scale returns were put under the […]