Mechanisms of Glucagon‐Like Peptide 1 Receptor Agonist‐Induced Facial Lipodystrophy and a Path Toward Prevention

ABSTRACT Background The emergence of a distinct facial appearance characterized by pronounced hollowing of the cheeks, temples, chin, and periorbital region has become a noteworthy side effect of treatment with glucagon-like peptide 1 receptor agonists (GLP-1RAs). This phenomenon presents a growing concern in both dermatology and aesthetic medicine. The reduction of facial adipose tissue in […]
IJMS, Vol. 26, Pages 11548: From Phytochemistry to Metabolic Regulation: The Insulin-Promoting Effects of Loureirin B Analogous to an Agonist of GLP-1 Receptor

IJMS, Vol. 26, Pages 11548: From Phytochemistry to Metabolic Regulation: The Insulin-Promoting Effects of Loureirin B Analogous to an Agonist of GLP-1 Receptor International Journal of Molecular Sciences doi: 10.3390/ijms262311548 Authors: Haowen Fang Xiaodong Sun Yanting Ding Siyuan Gu Bing Niu Qin Chen This study aimed to develop a potent, safe, and cost-effective small-molecule hypoglycemic […]
Healthcare, Vol. 13, Pages 3102: Exploring Adults’ Experiences with Tirzepatide for Weight Loss: A Mixed-Methods Study

Healthcare, Vol. 13, Pages 3102: Exploring Adults’ Experiences with Tirzepatide for Weight Loss: A Mixed-Methods Study Healthcare doi: 10.3390/healthcare13233102 Authors: Shukri Adam Fatma M. Ibrahim Eman Abdelaziz Ahmed Dabou Sneha Pitre Rania Aiman Shimaa AbdelSamad Background: Obesity confers substantial cardiometabolic risk. Tirzepatide, a once-weekly dual GIP/GLP-1 receptor agonist, produces dose-dependent weight loss in trials, but […]
Nutrients, Vol. 17, Pages 3735: Beyond Weight Loss: GLP-1 Usage and Appetite Regulation in the Context of Eating Disorders and Psychosocial Processes

Nutrients, Vol. 17, Pages 3735: Beyond Weight Loss: GLP-1 Usage and Appetite Regulation in the Context of Eating Disorders and Psychosocial Processes Nutrients doi: 10.3390/nu17233735 Authors: Isabel Krug An Binh Dang Jade Portingale Yakun Li Ying Qing Won Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have transformed treatment for higher weight and diabetes. Because they also […]
Beauty Is Changing Its Game Plan for the Ozempic Era

From surgery to supplements, GLP-1 medications are radically evolving the beauty space. We unpack the latest innovations.
Opinion: Public health should embrace GLP-1 drugs without abandoning obesity prevention

Following the White House’s recent announcement of price reductions and expanded coverage for GLP-1 medications like Wegovy and Zepbound, many patients searching for obesity treatments are about to gain access to highly effective options. The implications for U.S. public health are vast. Read the rest…
Get the Government Out of the GLP-1 Market

Its involvement often leads to distortions and perverse incentives. Dr. Gilberto de Lima Lopes Jr. is right that the market for medications is imperfect, but it is often government that is the culprit (“ The Free Market Alone Won’t Cut GLP-1 Prices,” Letters, Nov. 21). Oncology, his speciality, is the …
Diagnostics, Vol. 15, Pages 3025: Beyond BMI: Rethinking Obesity Metrics and Cardiovascular Risk in the Era of Precision Medicine

Diagnostics, Vol. 15, Pages 3025: Beyond BMI: Rethinking Obesity Metrics and Cardiovascular Risk in the Era of Precision Medicine Diagnostics doi: 10.3390/diagnostics15233025 Authors: Maria-Daniela Tanasescu Andrei-Mihnea Rosu Alexandru Minca Andreea-Liana Rosu Maria-Mihaela Grigorie Delia Timofte Dorin Ionescu Obesity remains a dominant risk factor for cardiovascular disease, yet its classification continues to rely heavily on body […]
JCM, Vol. 14, Pages 8413: Epicardial Fat and Heart Failure in Type 2 Diabetes: Metabolism, Imaging and Novel Biomarkers—A Translational Perspective

JCM, Vol. 14, Pages 8413: Epicardial Fat and Heart Failure in Type 2 Diabetes: Metabolism, Imaging and Novel Biomarkers—A Translational Perspective Journal of Clinical Medicine doi: 10.3390/jcm14238413 Authors: Pedro Gil-Millan José Rives José Luis Sánchez-Quesada Antonio Pérez Heart failure (HF) is a major cardiovascular complication in people with type 2 diabetes (T2D), where heart failure […]
Thanksgiving foods to skip while taking ozempic or other weight-loss drugs, says dietitian

For individuals taking GLP‑1 medications such as Ozempic, Thanksgiving doesn’t have to be restrictive, but specific foods and beverages need caution. Dietitian Kylie Bensley recommends avoiding mac and cheese, candied yams, and heavy or cream-based alcoholic drinks because of their impact on blood sugar and digestion. Safer choices are protein packed foods, vegetables, light desserts […]