Large Number of GLP-1 Prescriptions Go Unfilled

(MedPage Today) — Nearly half of patients prescribed a GLP-1 receptor agonist were not filling the order, with certain factors playing a role, according to a cohort study. Among nearly 10,000 GLP-1 receptor agonist prescriptions given at a single…
Can Novo Nordisk’s Aggressive Deal-Making Offset Semaglutide Reliance?

Novo Nordisk NVO continues to derive the bulk of its revenue from its blockbuster semaglutide (GLP-1 RA) therapies, Wegovy for obesity and Ozempic for type II diabetes (T2D). Together, the drugs generated DKK 101.41 billion in the first half of 2025, representing about 65% of total sales. However, this heavy dependence has made the company […]
STAT+: AstraZeneca to make obesity drugs in new Virginia plant

Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Quick programming note: This newsletter will take a break for the Monday holiday, but we’ll be back in your inbox bright and early Tuesday. We’re lining up some great stories for next week, and […]
Exclusive-Bill Gates, PAHO Consider Ways to Bring Weight-loss Drugs to Lower-income Countries

The Gates Foundation and the Pan American Health Organization are both working on ways to make weight-loss drugs like Novo Nordisk’s Wegovy and Eli Lilly’s Mounjaro more… Reuters Health Information
Novo Nordisk Seeks to Expand Liver Disease Treatments in $5.2B Deal for Bay Area Biotech

Novo Nordisk has reshaped countless waistlines. Now the Ozempic maker is aiming a little higher in the abdomen. The Danish pharma giant announced Thursday that it will acquire San Francisco-based Akero Therapeutics for $5.2 billion, adding a promising liver-treatment candidate to its pipeline as new CEO Mike Doustdar tries to revive once meteoric growth that […]
Ozempic and similar drugs could interfere with common medical procedure, research warns

Researchers have revealed a surprising new side effect linked to GLP-1 agonists, such as Ozempic, Wegovy, Mounjaro and Zepbound. These popular treatments for diabetes and obesity could interfere with medical imaging, such as PET and CT (“CAT”) scans. CT scans are often used to get detailed internal images to detect injuries, tumors or other abnormalities, […]
Tirzepatide Equally Effective for HFpEF in Men, Women

Efficacy of tirzepatide does not differ significantly between men and women, despite sex-specific differences in obesity-related heart failure with preserved ejection fraction. Medscape Medical News
Impact of Semaglutide on fat mass, lean mass and muscle function in patients with obesity: The SEMALEAN study

Abstract Aims Semaglutide, a GLP-1 receptor agonist, has shown efficacy in promoting weight loss. However, limited data exist on its impact on lean mass, muscle function, and metabolic adaptations. The SEMALEAN study aims to evaluate these parameters in patients with obesity treated with Semaglutide (2.4 mg). Materials and Methods This prospective study enrolled 115 patients with […]
Fat jabs helped me lose 10.5st after I’d been obese since childhood – now I feel 21 instead of being in an early grave

A MUM who battled obesity from a young age has shared how she was eating her way toward an early grave before trying weight loss jabs. She splurged £2,000 on the medication, but it enabled her to finally shift the weight and gave her a new lease on life. Tina Bashford was already classed as […]
Carolyn Hax: Image-conscious family finds new ways to harp on weight

With GLP-1 drugs in the mix now, a 30-something letter writer is under all new pressure from weight-obsessed parents.