GLP-1 signaling in tumor metabolism and immunity: mechanisms and strategies

Food Funct., 2025, Advance ArticleDOI: 10.1039/D5FO03273C, Review Article Yingzhe Luo, Huimin Xu, Yaqin Zhao, Biao Yang, Ying ZhangGLP-1 receptor agonists modulate tumor metabolism and immunity by restoring mitochondrial function, reversing the Warburg effect, and enhancing antitumor responses, offering therapeutic potential across cancers.To cite this article before page numbers are assigned, use the DOI form of […]

3 GLP-1 updates

In October, GLP-1 manufacturers inked partnerships with big-box retailers to increase access as several studies indicate a low adherence rate for the expensive medications.  Three updates on the GLP-1 drug class:  1. Prescriptions go unfilled Despite expanded approvals for conditions beyond obesity and Type 2 diabetes, the GLP-1 drug class is experiencing a drop in […]

Recent Developments in Retinal Disease

(MedPage Today) — Thus far in 2025, notable developments in retinal disease have included several newsworthy associations with the widely used GLP-1 agonist drugs for diabetes and weight loss, a study of patient satisfaction with treatment for…

Fruitist rides healthy snacking wave with $150m raise: GLP-1 consumers buy more berries

Superfruit specialist Fruitist has closed $150 million in equity financing led by a vehicle managed by J.P. Morgan Asset Management alongside other new and existing investors to help accelerate its global expansion. The round follows a period of meteoric growth at the vertically integrated firm, said CEO Steve Magami, who co-founded the business in 2012 […]

Walmart to offer in-store pickup for Zepbound

Eli Lilly and Walmart have partnered to offer in-store pickup of Zepbound (tirzepatide) single-dose vials through the LillyDirect platform by mid-November. The collaboration marks the first time patients using LillyDirect, the company’s direct-to-consumer healthcare platform, will be able to access self-pay pricing for Zepbound vials at a retail pharmacy, according to an Oct. 29 news […]

Obesity on decline in US as GLP-1 use skyrockets: Gallup

The obesity rate in the U.S. has seen a marked decline over the last three years, as the share of Americans who report using GLP-1 agonists for weight loss skyrockets, according to data from Gallup. In the latest report from the Gallup National Health and Well-Being Index, published Tuesday, 37 percent of American adults are…

What’s the Driving Force Behind Eli Lilly’s Recent Acquisition Spree?

Eli Lilly LLY has been on an acquisition spree since the beginning of this year to bolster its pipeline, which should drive long-term growth. Although the cardiometabolic health space remains its core area, the company is also expanding strategically across various other therapeutic areas, like oncology, neuroscience and ophthalmology, through targeted deals. Last week, Lilly […]