Liraglutide for Alzheimer’s disease . . . and other research
High dose flu vaccine and hospitalisationsWhenever flu hits the headlines, as it has this winter, attention inevitably turns to the flu vaccine. Might a higher dose be more effective in older adults? A trial set in Denmark randomised adults 65 years of age or older to receive either a high dose or standard dose quadrivalent […]
GLP-1 receptor agonists and next-generation metabolic hormone therapies in chronic kidney disease
Nature Reviews Nephrology, Published online: 08 January 2026; doi:10.1038/s41581-025-01036-y Targeting incretins is emerging as an effective approach to treat cardiovascular–kidney–metabolic syndrome. Here, the authors examine the biological effects of incretins and other metabolic hormones, such as glucagon and amylin, as well as discussing current clinical data demonstrating the organ-protective effects of incretin drugs and their […]
Amylyx Pharmaceuticals Announces Nomination of AMX0318 as a Novel, Long-Acting GLP-1 Receptor Antagonist Development Candidate, Identified in Collaboration with Gubra A/S
CAMBRIDGE, Mass.–(BUSINESS WIRE)–Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (“Amylyx” or the “Company”) today announced the selection of AMX0318, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist, as a development candidate for post-bariatric hypoglycemia (PBH) and other rare diseases. AMX0318 was identified through a research collaboration with Gubra A/S (“Gubra”), a company specializing in peptide-based drug discovery and […]
Berberine Facts: Is It a Natural GLP-1 Alternative?
Obesity biotech Alveus gains $160M for push into MariTide’s backyard
Another obesity biotech has entered the fray as tirzepatide and semaglutide fly off pharmacy shelves. Alveus Therapeutics disclosed a $159.8 million Series A on Thursday morning to create medicines that drive better quality of weight …
Stopping Ozempic or Mounjaro? The weight may come back faster than you think
New research shows people regain weight far faster after stopping obesity drugs than after dieting, with benefits fading quickly and raising questions about how long GLP-1 medicines need to be taken
Opinion: Do Americans expect too much from drugs?
A magic drug just got a little more magical on Monday, when a pill version of Wegovy, Novo Nordisk’s GLP-1 for weight loss, arrived in pharmacies nationwide. Previously only available by injection, everyone seems thrilled about the new pill — patients, physicians, and particularly investors, who have sent shares of Novo Nordisk up 15% since […]
Pharmaceutics, Vol. 18, Pages 81: Ketamine in Diabetes Care: Metabolic Insights and Clinical Applications
Pharmaceutics, Vol. 18, Pages 81: Ketamine in Diabetes Care: Metabolic Insights and Clinical Applications Pharmaceutics doi: 10.3390/pharmaceutics18010081 Authors: Shiryn D. Sukhram Majandra Sanchez Ayotunde Anidugbe Bora Kupa Vincent P. Edwards Muhammad Zia Grozdena Yilmaz Background: Depression and diabetic neuropathy (DN) commonly complicate diabetes and impair glycemic control and quality of life. Ketamine and its S-enantiomer, […]
Trump’s ‘beautiful’ new law means states have big decisions this year on Medicaid, SNAP and taxes
President Donald Trump listens as Centers for Medicare & Medicaid Services administrator Dr. Mehmet Oz speaks during an executive order signing in the Oval Office of the White House, Thursday, Dec. 18, 2025, in Washington. (AP Photo/Evan Vucci) 2026-01-08T06:07:56Z States have major decisions to make in 2026 about the social safety net and taxes in […]
The problem with blaming everything on inflammation
Chronic inflammation is a modern health problem — one that too many wellness influencers oversimplify. Inflammation is on everybody’s minds these days, and it seems like wherever you look, someone is telling you how to reduce your inflammation, from influencers on your TikTok feed or Instagram reels to even US Health Secretary Robert F. Kennedy Jr. […]