Glucose is a ligand-like trigger for secretion of postprandial GLP-1
Glucagon-like peptide 1 (GLP-1) is secreted from the intestinal L cells in a glucose-dependent manner. However, the mechanism underlying how glucose stimulates the secretion remains unclear. Here, we found that glucose at postprandial concentrations near the Km of GK for glucose (~10 mM), as well as nonmetabolizable glucose analogs, triggers GLP-1 secretion by intestinal L […]
Why Donated Lifeless Bodies Are Being Used For BBLs And Breast Implants Now
Across the U.S., a new and controversial cosmetic trend called AlloClae is gaining traction, which utilizes purified fat from donated cadavers to enhance the body through procedures such as Brazilian b**t lifts (BBLs), breast augmentation, and hip-dip correction. The rise of this donor-derived fat filler is being driven by changing body types fueled by weight-loss […]
Business news: MLK events and new firefighters graduate
PNW sets MLK Day events Purdue University Northwest has scheduled celebrations of the Rev. Martin Luther King Jr.’s life and legacy through free programming on Jan. 15 and Jan. 19 at the Hammond and Westville campuses, according to a release. PNW’s Jan. 15 MLK Day celebration runs from 12:30-2 p.m. in Alumni Hall of the […]
Professor Tim Spector issues dire health warning over skinny jabs
The nutritional expert spoke out as more and more of us start using GLP-1 medications
I got a GLP-1 drug with few questions asked… and never meeting a doctor face-to-face. But could that convenience have put my health at risk?
I lied repeatedly throughout my online application for a GLP-1 medication, convinced that – at some point – I would be face a medical provider and my whole canard would be exposed.
Which Country Has The Best Healthcare? | Dr. Zeke Emanuel
I’ll teach you how to become the media’s go-to expert in your field. Enroll in The Professional’s Media Academy now: https://www.professionalsmediaacademy.com/ Listen to my podcast, The Checkup with Doctor Mike, here: Spotify: https://go.doctormikemedia.com/spotify/CheckUpSpotify Apple Podcasts: https://go.doctormikemedia.com/applepodcast/ApplePodcasts Thanks to Dr. Zeke Emanuel for appearing in the show. Buy his new book here: https://www.ezekielemanuel.com/books 00:00 Intro 01:53 […]
Fight Aging! Newsletter, January 5th 2026
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter, please visit: https://www.fightaging.org/newsletter/. To unsubscribe, send email or reply to […]
Pharmaceutics, Vol. 18, Pages 69: Liraglutide and Exenatide in Alzheimer’s Disease and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis of Cognitive Outcomes
Pharmaceutics, Vol. 18, Pages 69: Liraglutide and Exenatide in Alzheimer’s Disease and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis of Cognitive Outcomes Pharmaceutics doi: 10.3390/pharmaceutics18010069 Authors: Paula Santos Alberto Souza Sá Filho Vicente Aprigliano Amanda G. Duarte Natã Alegransi Ribeiro Katia Marques Lombardo James Oluwagbamigbe Fajemiroye Artur Prediger Buchholz Victor Renault Vaz Gaspar R. […]
How A Wall Street Analyst Started A $4 Billion Obesity Drug Company
Brian Lian founded publicly traded Viking Therapeutics to focus on metabolic diseases. With obesity drugs in development and the GLP-1 space booming, it’s now a prime M&A target for giants jostling for their share of a potential $100 billion market.
Something Grim Is Happening to People Who Go Off GLP-1s
Many people who successfully lost weight on Ozempic and other GLP-1 agonist drugs are having trouble weaning themselves off the injectables, according to the BBC, because the hunger for food comes roaring back with a vengeance — and hence the pounds start creeping up again, hinting that patients are likely to develop life-long dependencies on the […]