‘The Beauty’ Review: Ryan Murphy Gets His Groove Back With Graphic Sci-Fi Drama

Ryan Murphy’s been having a rough go at winning over viewers lately. His most recent shows, “Monster: The Ed Gein Story” and “All’s Fair,” flopped with critics but gathered early viewer attention before fading out. So when ads for his latest show immediately began to elicit comparisons to the 2024 award-winning film, “The Substance,” it […]

STAT+: Novo strikes deal for diabetes cell therapies

Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. We’re breaking down some of the key parts of a sweeping new health care bill today. The need-to-know this morning Johnson & Johnson kicked off the fourth-quarter earnings season with in-line profits […]

Ozempic just released its own version of the iconic Mac vs. PC ad

Novo Nordisk’s ‘There’s Only One Ozempic’ campaign is about reasserting the drugmaker’s brand name in an increasingly competitive landscape. Ozempic-maker Novo Nordisk turned to the actors from Apple’s 2000s “Get a Mac” ads to differentiate its GLP-1 medication amid a rising sea of competitors.

Efsubaglutide Alfa attenuates metabolic dysfunction‐associated steatohepatitis in mice with improvements in second harmonic generation‐derived fibrosis features

Abstract Aims Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease with limited effective treatments. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promise for metabolic and hepatic benefits. This study evaluated the therapeutic efficacy of Efsubaglutide Alfa, a novel long-acting GLP-1RA, in a mouse model of MASH. Materials and Methods Male C57BL/6J mice with diet-induced […]