Prolonged signaling of backbone-modified glucagon‐like peptide‐1 analogues with diverse receptor trafficking
Proceedings of the National Academy of Sciences, Volume 122, Issue 14, April 2025. <br/>SignificanceGlucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonists are useful for the treatment of type 2 diabetes and obesity. Controlling GLP-1R signaling parameters, including duration and subcellular location, is an important goal for mechanistic …
Rare sugars curb appetite and mimic diabetes drugs in mice
Rare sugars like D-allulose, D-tagatose, and D-sorbose significantly boosted GLP-1 secretion and suppressed food intake in mice. D-allose also reduced food intake through a unique, GLP-1-independent pathway.
HIMS Expands Telehealth Offerings with Eli Lilly’s GLP-1 Drugs
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GLP-1 spending hits $5.8B for adults without diabetes
A new study found that spending on GLP-1 medications such as Ozempic, Wegovy and Zepbound surged to $5.8 billion in 2022 among U.S. adults without diabetes. The research, published April 1 in the Annals of Internal Medicine, showed the number of non-diabetic adults using these drugs — which are also prescribed for weight loss — […]
Eli Lilly sues Empower, Strive over tirzepatide products
Eli Lilly has sued two large compounding pharmacies, alleging they deceive patients and put them at risk with compounded versions of the obesity drug tirzepatide in combinations or forms that haven’t been …
Here’s how much Ozempic and similar drugs have soared in popularity since 2018
The use of GLP-1 meds — made popular by Ozempic (NVO) — among U.S. adults without diabetes more than tripled between 2018 and 2022, with annual spending surging from $1.6 billion to $5.8 billion. Read more…
FDA Approves Semaglutide to Reduce Risk of Kidney Disease Progression
Semaglutide, marketed as Ozempic, recently became the first glucagon-like peptide 1 (GLP-1) receptor agonist approved by the US Food and Drug Administration (FDA) to reduce the risk of worsening kidney disease, kidney failure, and death due to cardiovascular disease in adults with type 2 diabetes (T2D) and chronic kidney disease (CKD), a common complication of […]
Costly GLP-1 drug use for weight loss has soared, study reports
The number of Americans taking cutting-edge weight-loss drugs like Ozempic, Wegovy and Zepbound has skyrocketed in recent years, a new study says.
GLP-1 Drug Use For Weight Loss Has Soared, Costing Billions
By Dennis Thompson HealthDay ReporterTUESDAY, April 1, 2025 (HealthDay News) — The number of Americans taking cutting-edge weight-loss drugs like…
Nurse reveals what you MUST drink if you are on GLP-1 meds like Ozempic and Mounjaro
A nurse has revealed exactly what you need to be drinking when you’re on a GLP-1 medication – and why hydration on the medication is so important.