CMS shares GLP-1 model: 7 notes

CMS published plans Dec. 23 for its voluntary “Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth” — or BALANCE — model. The announcement comes weeks following the White House’s agreements with Eli Lilly and Novo Nordisk to apply most-favored-nation pricing for drugs that treat obesity, diabetes and related conditions. “Today’s announcement builds upon our […]

S&P 500 surges to record after strong US economic report

The S&P 500 finished up 0.5% at 6,909.79, narrowly topping a record set earlier this month. (EPA Images pic) NEW YORK: The S&P 500 powered to a fresh record Tuesday following data showing surprisingly robust third-quarter US economic growth as markets hope for a year-end “Santa Claus Rally”. All three major Wall Street indices advanced, […]

Tirzepatide Synergizes with Leptin on Weight Loss and Restoring Metabolic Homeostasis in Diet-induced Obesity Model

Leptin resistance limits anti-obesity efficacy. We identified a leptin-sensitizing mechanism through tirzepatide (TZP), a glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) dual-agonist. Our tirzepatide clinical trial revealed that circulating leptin levels at baseline correlated with weight loss efficacy in patients with obesity, suggesting leptin and tirzepatide could interact to achieve stronger effects […]

US Economy Expands 4.3 Percent in Third Quarter, Topping Expectations

The Commerce Department reported that the U.S. economy grew 4.3 percent in the third quarter, topping expectations. NTD looks at what drove the uptick. A significant change in America’s skies. The Federal Communications Commission is planning to ban the next generation of Chinese-made drones, citing them as a national security risk. The Food and Drug […]

Wegovy is coming in pill form. Here’s when, how much, and how well it works

People who are squeamish about needles will soon have an alternative, as the Food and Drug Administration has approved a pill version of Wegovy that could be available as soon as next month. Novo Nordisk, maker of the GLP-1 weight-loss drug, announced on Monday that it has received FDA approval for its once-daily pill that […]

New Wegovy pill offers needle-free weight loss — but may not work for everyone

The first-ever oral GLP-1 medication for weight loss has been approved for use in the U.S. The Wegovy pill, from drugmaker Novo Nordisk, was cleared by the Food and Drug Administration to reduce excess body weight, maintain long-term weight reduction and lower the risk of major cardiovascular events. Approval of the once-daily 25mg semaglutide pill […]