‘Another self own’: Trump comment sparks internet rumors of president on Ozempic
President Donald Trump touted Friday his new health care plan, which he dubbed “The Great Health Care Plan” during a press conference from the White House, but his meandering remarks about a “friend” who took the weight-loss drug Ozempic quickly fueled online speculation about whether the president himself was using it. “A friend of mine […]
‘Shamed’ Oprah Winfrey ‘Blamed Herself’ for Packing on the Pounds Before Using Weight Loss Medications to Shed 50Lbs — And Now She Can’t Quit the Jabs
Oprah dropped about 50 pounds after going on GLP-1 drugs two and a half years ago, but then quickly gained back 20 pounds when she stopped taking them.
Signaling architecture of the glucagon-like peptide-1 receptor
The glucagon-like peptide-1 receptor (GLP-1R) is a class B1 G protein–coupled receptor and major therapeutic target in type 2 diabetes and obesity. Beyond its canonical role in Gαs/cAMP signaling, GLP-1R is increasingly recognized as an organizer of spatiotemporally defined signaling nanodomains, or “signalosomes.” This Review highlights our current knowledge on the mechanisms of assembly and […]
GLP-1 physiology and pharmacology along the gut-brain axis
Historically, antiobesity medications have been modestly effective at best, with side-effect profiles that limit compliance and often preclude the long-term therapy required to maintain weight loss. Recently developed therapies based on analogs of the gut hormone glucagon-like peptide-1 (GLP-1) have transformed the medical management of obesity, leading both to a degree of weight loss that […]
Food Exec Brief: Margin Preservation’s Urgent Mandate, AI’s Workforce Revolution, and Alternative Protein’s Commercial Breakthrough
Welcome to this week’s Food Exec Brief, your strategic intelligence roundup covering the industry’s desperate fight to preserve margins amid relentless cost pressures, AI and robotics emerging as the only viable solution to catastrophic labor shortages, and alternative proteins finally achieving commercial viability as manufacturers race to capture the $290 billion opportunity reshaping protein markets. […]
Long-term GLP-1 use trims medical cost growth: Aon
Long-term GLP-1 use slows medical cost growth, according to findings published Jan. 13 from professional services firm Aon. The firm analyzed 192,000 GLP-1 users from July 2022 to March 2025, comparing outcomes to non-users, through commercial medical and pharmacy claims data. This research builds off 2025 analyses. “These results provide employers a much clearer view […]
Taco Bell rolls out new ‘luxe’ $3 value menu as fans debate the tradeoffs
A major fast-food chain is revamping its value menu as diners grow more price-conscious — and the early reaction is split. Taco Bell is expanding its value offerings with the launch of its new Luxe Value Menu, featuring 10 items priced at $3 or less. The menu, which debuts nationwide Jan. 22 and combines five […]
Summary of JP Morgan Conference in Obesity and Metabolic Diseases
Here’s a summary of the major announcements and trends from the 44th Annual JP Morgan Healthcare Conference in San Francisco (January 12–15, 2026) specifically in the areas of obesity, weight-loss drugs, metabolic disease, and adjacent therapies: (BioSpace) Fierce Biotechscanx.tradeReutersReutersAd Hoc News 🧠 1. Shift Toward Oral Obesity DrugsA major theme at JPM 2026 was the […]
Day 1 @ JP Morgan in Obesity Drugs and Therapies
JP Morgan 2026: Obesity & GLP-1 Therapies Take Center StageWhat the Latest Deals and Data Mean for the Future of Metabolic MedicineThe J.P. Morgan Healthcare Conference once again served as the bellwether for where biotech and pharma are headed—and in 2026, GLP-1 and obesity therapeutics dominated the conversation.From next-generation incretin drugs to RNA-based obesity targets […]
Day 2 @ JP Morgan in Obesity Drugs and Therapies
Here are the **highlights from Day 2 of the JP Morgan Healthcare Conference (San Francisco) specifically related to obesity, weight-gain therapies, and related drug developments Fierce PharmaPharmaceutical TechnologyReutersFierce BiotechPharmaceutical Technology 🧪 New & Emerging TherapiesAmgen’s MariTide weight-loss programAmgen touted positive data on its experimental obesity drug MariTide, showing the therapy helped trial participants maintain significant […]