Gut-derived GLP-1 released by rare sugar D-allulose cooperates with insulin to activate left-sided vagal afferents and enhance insulin sensitivity

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) ameliorate hyperglycemia by directly stimulating insulin secretion from the pancreas. In contrast, the physiological role of short-lived endogenous GLP-1 remains unclear, largely because of its limited access to pancreatic {beta} cells. Here, we show that D-allulose-induced intestinal GLP-1 secretion (AIGS) cooperates with insulin to reduce blood glucose levels by enhancing […]

Doctors urge caution as study finds rapid weight regain after weight-loss drugs

A study found people who stopped GLP-1 weight-loss drugs such as Ozempic, regained weight rapidly and faced higher risks of diabetes, high cholesterol and high blood pressure. #weightloss #health For more info, please go to https://globalnews.ca Subscribe to Global News Channel HERE: http://bit.ly/20fcXDc Follow Global News on X HERE: http://bit.ly/1Toz8mt Follow Global News on TikTok […]

Wegovy just became available in an unexpected place

Days after hitting the market, the new pill version of Novo Nordisk’s wildly popular weight-loss drug will be available through Amazon’s online pharmacy. Amazon joins telehealth providers, discount prescription stalwart GoodRx, and even Novo Nordisk itself in providing the novel weight-management drug for consumers who want to pay out of pocket.  With the introduction of […]

You’re Doing This Right — And Still Not Burning Fat | Dr. Mandell

Many people eat healthy, cut sugar, and still struggle with stubborn fat, low energy, or blood sugar swings. In this video, Dr. Mandell explains why fat loss is not just about what you eat, but how your body interprets a meal at the physiological level. Learn how eating speed influences digestion, insulin signaling, cortisol, and […]