GLP-1 in joint fluid may let weight-loss drugs target arthritis directly

Thursday, April 16, 2026 – Friday, April 17 - Arthritis includes a range of conditions that affect the joints, from inflammatory diseases such as rheumatoid arthritis and psoriatic arthritis to more common conditions like osteoarthritis. Many people experience pain, stiffness, and a reduced quality of life. Treatment today focuses on reducing inflammation and relieving symptoms, depending on the type of arthritis. However, researchers from the Department of Biomedicine at Aarhus University have now identified a new possible route for future treatments. Their research is published in The Lancet Rheumatology journal.

How to Know If Insurance Will Cover Your GLP-1 Medications

Thursday, April 16, 2026 – Friday, April 17 - A recent poll found 1 in 8 adults take a GLP-1 medication like Ozempic or Wegovy and 27 percent of those users said even though they have insurance, they still pay out-of-pocket for those drugs. NBC News medical contributor Dr. Natalie Azar and chief business correspondent Christine Romans join TODAY to break down the different weight loss drugs, how to know if your insurance will cover them and more.

GLP-1s don’t work for everyone: Why, and what to do?

Wednesday, April 15, 2026 – Thursday, April 16 - Over the past few years, GLP-1 receptor agonists have been growing in popularity for weight loss.

While many people lose between 5-15% of their starting body weight while on a GLP-1, as much as 20% of people may not respond to the drug.

Recent research has found that a person’s genetic makeup may explain why some people do not respond to GLP-1 drugs.

A new review suggests that taking both a GLP-1 medication, and a medication that combines both naltrexone and bupropion into one pill, may be helpful for those who are not responding to GLP-1s alone.