Semaglutide improves vascular responsiveness to insulin

Monday, April 27, 2026 – Tuesday, April 28, - Glucagon-like peptide-1 receptor agonists, known as GLP-1 drugs, are highly effective at helping people lose weight and substantially lower the risk of heart attacks, strokes, and death from heart disease. A new study conducted in mice suggests that the drugs' effect on how blood vessels respond to insulin may be a key driver of this cardiovascular benefit in those with obesity.

Mounjaro, Zepbound Lower Death Risk for People With Serious Heart Conditions

Friday, April 24, 2026 – Saturday, April 25 - GLP-1 drugs containing tirzepatide significantly reduce cardiovascular risks in people with serious heart conditions. Indranil MUKHERJEE / AFP via Getty Images

GLP-1 weight loss medications containing tirzepatide (Mounjaro, Zepbound) can reduce heart-related health risks for people with serious heart conditions, according to new research.