What are GLP-1 medicines? Do they help with weight loss and diabetes, and what are their side effects?
GLP-1 medications are prescription treatments used in the UK to manage type 2 diabetes and, in certain cases, medically supervised weight loss. They function by mimicking hormones that control appetite and blood sugar, making people feel fuller. Only specific GLP-1 drugs are licensed by the MHRA, and they must be prescribed by healthcare experts. Regulators […]
The Century of History Shaping the Debate Over GLP-1s
The debate over whether insurers should pay for GLP-1 drugs like Ozempic and Wegovy has revived a familiar American argument about why people get sick. Some commentators have insisted that the powerful weight-loss drugs are “shortcuts” for people unwilling to exercise greater self-control, a concern echoed in coverage noting that experts worry too many patients […]
Ozempic is changing the foods Americans buy
When Americans begin taking appetite-suppressing drugs like Ozempic and Wegovy, the changes extend well beyond the bathroom scale. According to new research, the medications are associated with meaningful reductions in how much households spend on food, both at the grocery store and at restaurants.
Novo Nordisk Files NDA for Next-Generation Obesity Drug CagriSema
Novo Nordisk NVO announced the submission of a new drug application (NDA) to the FDA, seeking approval for its next-generation once-weekly injection, CagriSema, to reduce excess body weight and maintain weight reduction in the long term in adults with obesity or overweight. The FDA is expected to review the application in 2026. The candidate is intended […]
Altimmune advances in MASH; New China obesity biotech; Ipsen Phase 2 fail
Plus, news on: EpimAb, Boehringer and Nxera, Syneron, Amphix Altimmune goes to Phase 3 in MASH: The drug developer’s Phase 2 trial of pemvidutide, a GLP-1/glucagon agonist, failed in June. But based on a longer …
Did Eli Lilly Just Find the Holy Grail of Weight Loss?
Quick Read Eli Lilly (LLY) submitted an FDA application for orforglipron. The once-daily oral pill maintained weight loss after patients switched from injections. Lilly’s Zepbound achieved 20.2% average weight loss over 72 weeks versus 13.7% for Novo Nordisk‘s Wegovy in a Phase 3 trial. Novo Nordisk’s higher-dose oral semaglutide could be approved by year-end. Lilly’s […]
Lawsuits Allege Ozempic Is Causing Blindness
Ozempic and similar weight loss drugs have been found to cut risks for a variety of health issues — ranging from heart to kidney disease — netting the pharma companies behind them billions of projected dollars in revenue over the next decade. But in rare cases, this class of drugs called GLP-1 agonists can come […]
GLP-1 pills are on the way. Here’s what to know : Short Wave – NPR
GLP-1 pills are on the way. Here’s what to know : Short Wave NPR Wegovy Maker Novo Nordisk Files for FDA Approval of Obesity Drug CagriSema The Wall Street Journal Eli Lilly, Novo Nordisk file new weight-loss drugs that could be game changers in obesity medicine MarketWatch Novo files marketing application for next-gen weight-loss drug Reuters Healthy Returns: 2026 […]
IJMS, Vol. 27, Pages 27: The Roles of Incretin Hormones GIP and GLP-1 in Metabolic and Cardiovascular Health: A Comprehensive Review
IJMS, Vol. 27, Pages 27: The Roles of Incretin Hormones GIP and GLP-1 in Metabolic and Cardiovascular Health: A Comprehensive Review International Journal of Molecular Sciences doi: 10.3390/ijms27010027 Authors: Dai Yamanouchi The incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) play central roles in metabolic and cardiovascular regulation. GLP-1 receptor agonists (GLP-1RAs) are […]
The wellness wild west is back on its bullshit with unapproved weight loss drugs
The craze around “GLP-3” online is a peak example of the wellness wild west. This is Optimizer, a weekly newsletter sent every Friday from Verge senior reviewer Victoria Song that dissects and discusses the latest phones, smartwatches, apps, and other gizmos that swear they’re going to change your life. Optimizer will be taking a break for the holidays and will […]