Amy Schumer’s Transformation Through the Years: Motherhood and More

Amy Schumer went from a hustling stand-up comedian to a major movie star. “After my dad got MS and we went bankrupt and my mom left him, that period from age 12 to 15 was a really rough time,” Schumer recalled to GQ in a 2015 profile. “And we all suffered from it, my siblings […]

Best-Performing ETFs of November

Wall Street recorded a subdued November this year. The S&P 500 lost 0.04% over the past month (as of Nov. 28, 2025), the Dow Jones advanced 0.8%, and the Nasdaq Composite was off 0.9%. The ebbing chances of the Fed cutting rates in December weighed on markets in November.Concerns over a potential artificial intelligence (AI) […]

Wall Street Bulls are Pounding the Table Over Amazon, Eli Lilly, and Apple

Quick Read Wells Fargo just raised its price target on Amazon to $295 a share, with an overweight rating. Analysts at Bank of America reiterated a buy rating on Eli Lilly, with a price target of $1,286 from $950. Analysts at Bernstein just reiterated an outperform rating on Apple, noting that its checks show iPhone […]

WHO issues 1st guideline on GLP-1s: 4 updates

In a first, the World Health Organization has issued a guideline on GLP-1s, a drug class that up to 1 in 8 U.S. adults report using, according to KFF research.  The WHO’s guideline, published Dec. 1 in JAMA, recommends long-term use of GLP-1 medications be “combined with intensive behavioral therapy.” The guideline included several GLP-1s, […]

Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice

Glucagon-like peptide-1 receptor (GLP-1R) activation in the brain strongly reduces appetite, but most brain GLP-1Rs are not accessible for systemically administered GLP-1R agonists. Acute activation of nucleus tractus solitarius (NTS) GLP-1 neurons, targeting brain GLP-1Rs, strongly suppresses food intake separate from GLP-1R agonists. However, it is unknown if their chronic stimulation is a viable strategy […]