Trump GLP-1 Deal ‘Move in Right Direction’

Trump’s deal with drug manufacturers lowering the cost of GLP-1s will expand coverage for many patients. Caroline Messer, MD, explains why she welcomes this deal. Medscape Gastroenterology

Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice

Glucagon-like peptide-1 receptor (GLP-1R) activation in the brain strongly reduces appetite, but most brain GLP-1Rs are not accessible for systemically administered GLP-1R agonists. Acute activation of nucleus tractus solitarius (NTS) GLP-1 neurons, targeting brain GLP-1Rs, strongly suppresses food intake separate from GLP-1R agonists. However, it is unknown if their chronic stimulation is a viable strategy […]

Obesities, Vol. 5, Pages 88: Nutritional Approaches to Enhance GLP-1 Analogue Therapy in Obesity: A Narrative Review

Obesities, Vol. 5, Pages 88: Nutritional Approaches to Enhance GLP-1 Analogue Therapy in Obesity: A Narrative Review Obesities doi: 10.3390/obesities5040088 Authors: Denise Deo Dias Andrea Rodrigues Vasconcelos Ana Carolina Remondi Souza Caroline de Menezes Isabella Sobral Teixeira e Silva José João Name Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are highly effective in the management of obesity; […]