STAT+: Eli Lilly drug preserves lean mass in patients losing weight on Wegovy

CHICAGO — An investigational therapy from Eli Lilly helped preserve lean mass and drive greater loss of fat in patients taking the popular obesity treatment Wegovy. In a Phase 2 trial, patients taking the highest-dose combination of Wegovy and the drug, called bimagrumab, lost 22% of their weight at 72 weeks. Ninety-three percent of that […]

The quiet trends reshaping ag: a field guide for builders, backers, and business leaders

Mark S. Brooks is a venture strategist and corporate innovation leader with deep experience across agtech, biotech, climate, and entrepreneurship. A former academic climate scientist-turned-investor, Mark has deployed over $75 million in venture capital globally, led FMC Ventures, invested at Syngenta Ventures, and founded an agtech startup. While exploring his next senior leadership role, Mark […]

Efficacy and safety of danuglipron (PF‐06882961) in adults with obesity: A randomized, placebo‐controlled, dose‐ranging phase 2b study

Abstract Aims This randomized, double-blind, placebo-controlled Phase 2b study aimed to assess the efficacy, safety, and tolerability of danuglipron (PF-06882961), an oral small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist, in adults with obesity. Materials and Methods Eligible participants (aged 18–75 years; with obesity, without diabetes) were randomized to receive danuglipron or placebo twice daily (BID) for 26 […]

Diabetic patients taking GLP-1s may face increased risk of eye disease, study suggests

Diabetes is the leading cause of vision loss in people between 18 and 64 years old, according to the American Diabetes Association — and the best way to prevent this is to control blood sugar levels. Glucagon-like peptide-1 receptor agonists (GLP-1s), such as Ozempic and Mounjaro, have become popular medications for controlling diabetes and treating […]