Novo Nordisk says Alzheimer’s drug trial fails to meet main goal

Novo Nordisk’s shares fell 10% after the company said its oral semaglutide drug Rybelsus failed to meet the main goal in late-stage trials testing whether it could slow cognitive decline in early Alzheimer’s patients. The setback dims hopes for expanding GLP-1 medicines into a major new market beyond obesity and diabetes, reinforcing scepticism over Novo’s […]

Will Americans ever be able to afford weight loss drugs?

For nearly two years Nicole Cowart’s doctor recommended she take a glucagon-like peptide-1 (GLP-1) receptor agonist. The doctor said it would help her manage her prediabetes and leg swelling—but her insurance wouldn’t pay unless she was diagnosed with type 2 diabetes.Cowart ran out of treatment options and remembers her doctor hoping that she would develop […]

24th November – Threat Intelligence Report

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GLP-1 side effects – LAist

GLP-1 side effects  LAist Brain scientists are seeking weight-loss drugs without the nausea : Shots – Health News  NPR Brain activity associated with breakthrough food preoccupation in an individual on tirzepatide  Nature Better Than Ozempic? New Oxytocin Combination Could Eliminate Side Effects  SciTechDaily GLP-1 Drug May Offer Short-Term Control of Obsessive Food Cravings  U.S. News & World Report

STAT+: Novo Nordisk’s semaglutide fails to slow Alzheimer’s progression

Two trials testing the Novo Nordisk weight loss drug semaglutide in Alzheimer’s disease failed, the company said Monday, showing the medicine did not slow the progression of the condition versus placebo.  Studying semaglutide — the key ingredient in the blockbusters Ozempic and Wegovy — in Alzheimer’s was always seen as a long shot, even as […]