Novo Nordisk says Alzheimer’s drug trial fails to meet main goal

Novo Nordisk’s shares fell 10% after the company said its oral semaglutide drug Rybelsus failed to meet the main goal in late-stage trials testing whether it could slow cognitive decline in early Alzheimer’s patients. The setback dims hopes for expanding GLP-1 medicines into a major new market beyond obesity and diabetes, reinforcing scepticism over Novo’s […]
Will Americans ever be able to afford weight loss drugs?

For nearly two years Nicole Cowart’s doctor recommended she take a glucagon-like peptide-1 (GLP-1) receptor agonist. The doctor said it would help her manage her prediabetes and leg swelling—but her insurance wouldn’t pay unless she was diagnosed with type 2 diabetes.Cowart ran out of treatment options and remembers her doctor hoping that she would develop […]
Muscly people show slower brain ageing, study finds

Research highlights possible drawback of muscle mass loss through use of GLP-1 anti-obesity drugs
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GLP-1 side effects – LAist

GLP-1 side effects LAist Brain scientists are seeking weight-loss drugs without the nausea : Shots – Health News NPR Brain activity associated with breakthrough food preoccupation in an individual on tirzepatide Nature Better Than Ozempic? New Oxytocin Combination Could Eliminate Side Effects SciTechDaily GLP-1 Drug May Offer Short-Term Control of Obsessive Food Cravings U.S. News & World Report
GLP-1 Receptor Agonists Linked to Lower Infection Risk

GLP-1 receptor agonists are associated with a lower risk for serious infections, a recent meta-analysis suggests. Medscape Medical News
New weight-loss shot shows major fat reduction, but experts urge caution

An experimental medication was shown to help boost weight loss by up to 20%, a study found. Eloralintide, a once-weekly injectable manufactured by Eli Lilly in Indianapolis, led to “meaningful, dose-dependent weight loss” in adults who were overweight or obese but did not have diabetes, according to a press release. The drug was generally well-tolerated […]
GLP-1 Drug May Offer Short-Term Control of Obsessive Food Cravings

By Ernie Mundell HealthDay ReporterMONDAY, Nov. 24, 2025 (HealthDay News) — Researchers say a woman struggling with obesity who couldn’t resist…
People taking weight loss jabs could be at risk of pancreas issues

GLP-1 medicines, such as tirzepatide (Mounjaro) and semaglutide (Wegovy) work by making people feel fuller for longer
Novo Nordisk’s semaglutide misses in closely-watched Alzheimer’s trials

Novo Nordisk’s bet on semaglutide in Alzheimer’s disease was always a long shot, and like most long shots, it has missed the mark. The GLP-1 agonist failed to delay disease progression in patients in two …