The Executive Briefing: Saks in Crisis; The Battle for Lululemon; A Holiday Shopping Miracle

America’s largest department store operator is on the brink, Lululemon’s founder is making moves and GLP-1 pills promise to shake up fashion this year. Read on for your concise breakdown of November’s key developments from executive editor Brian Baskin.
Thursday briefing: Why skinny jabs’ short-term fix comes with long-term concerns

In today’s newsletter: A new study shows that people don’t just regain weight after stopping GLP-1 drugs, they see other positive health markers reverse – leading to questions about long-term impacts and solutions Good morning. If you are as chronically online as I am, you have probably noticed a major shift by some of your […]
Brain Stimulation Matches Semaglutide for Weight Loss

In a retrospective study, repetitive transcranial magnetic stimulation produces weight loss comparable to semaglutide 0.5 mg/wk in patients with obesity and type 2 diabetes. Medscape Medical News
Thai FDA seeks to tighten controls on GLP-1 ‘slimming pens’, proposing special controlled-drug status

The move will limit sales to pharmacies with a doctor’s prescription amid misuse online.
Exacerbation of sucrose-induced visceral obesity and glucose intolerance by ovariectomy and its GLP-1-dependent amelioration by the rare sugar D-allulose

Estrogen deficiency after menopause promotes visceral fat accumulation and insulin resistance, thereby increasing the risk of type 2 diabetes. Although hormone replacement therapy is partially effective, its use is limited by increased risks of cardiovascular disease and breast cancer, underscoring the need for safer preventive strategies. The rare sugar D-allulose has been reported to stimulate […]
People coming off weight-loss injections risk fast weight gain – BBC

People coming off weight-loss injections risk fast weight gain BBC People who stop taking GLP-1 drugs regain weight faster, review finds CBC Less than two years after stopping obesity drugs, weight and health issues return, study finds Reuters People who stop taking weight-loss jabs regain weight in under two years, study reveals The Guardian How eggs can help you […]
People who stop taking GLP-1 drugs regain weight faster, review finds

When people who are overweight and obese stopped taking their weight-loss medications they regained weight faster than those who stopped a diet or exercise program, a new review of studies finds.
People who stop taking weight-loss jabs regain weight in under two years, study reveals

Analysis finds those who stopped using medication saw weight return four times faster compared with other weight loss plans People who stop taking weight loss jabs regain all the weight originally lost in under two years, significantly faster than those on any other weight loss plan, according to a landmark study. Weight loss medications, known […]
Weight lost on GLP-1 drugs is regained within two years of stopping

The sustainability of weight-loss drugs is under scrutiny as new research shows that people who stop taking glucagon-like peptide-1 (GLP-1) agonists regain the pounds at a steady rate, returning to their original size after around 1.7 years. The findings raise questions about whether this “magic cure” for obesity is actually unsustainable without a life-long commitment […]
What Nvidia just did could rewire the AI race

Nvidia isn’t going to wait until spring. The AI chipmaker just changed the rules for its competitors and maybe for the whole AI infrastructure timeline, as CES 2026 is still going strong. CEO Jensen Huang used the stage in Las Vegas to show off Nvidia’s next-generation AI server platform, Vera Rubin, months before it was […]