Popular obesity drug fails in hotly anticipated Alzheimer’s trials
The studies may still hold clues to the powers and limits of GLP-1 drugs
The complicated relationship between GLP-1s and pregnancy – The Washington Post
The complicated relationship between GLP-1s and pregnancy The Washington Post Patients who discontinue GLP-1s found to have more weight gain, complications during pregnancy Medical Xpress New Moms’ GLP-1 Prescriptions Jumped After Wegovy Approval MedPage Today New fat jab warning as pregnancy risks revealed, even after stopping use – from ‘premature birth to extra weight gain’ The Sun How does […]
There’s still hope GLP-1 drugs could slow the second-biggest type of dementia
Can GLP-1s treat vascular dementia? One study failed, but some researchers are holding out hope.
Highly Anticipated Alzheimer’s Trials Yield Disappointing Results for GLP-1 Drug
(MedPage Today) — The oral GLP-1 receptor agonist semaglutide (Rybelsus) did not slow Alzheimer’s disease progression in the highly awaited EVOKE phase III trials, Novo Nordisk announced Monday. The company shared topline results from the 2-year…
What Comes Back When Stopping GLP-1s?
We knew the weight would return, but what happens to the other benefits when patients are no longer taking GLP-1 drugs? Medscape
Stopping GLP-1s for Pregnancy Linked to Weight Gain, Complications
(MedPage Today) — The recommended discontinuation of GLP-1 receptor agonists during pregnancy was associated with more gestational weight gain and higher risks of pregnancy complications, according to an analysis of health records that primarily…
Study finds GLP-1 drug might help curb obsessive food cravings
Researchers say a woman struggling with obesity who couldn’t resist eating fatty foods experienced declines in her cravings after taking tirzepatide.
GLP-1 Pill Fails to Slow Alzheimer’s Progression in Clinical Trial
Top-line results from two large clinical trials by Novo Nordisk, the company behind Ozempic and Wegovy, found oral semaglutide failed to slow down Alzheimer’s progression
Alcohol And Fructose, Tangled (and Untangled?)
This paper advances a metabolic hypothesis that I certainly didn’t see coming. One of the great mysteries about alcoholism/alcohol use disorder is its underlying biochemical drivers. There’s obviously a behavioral and psychological component, but there are physical and metabolic ones too, and trying to untangle those has been an effort of many decades. The authors […]
GLP-1s Are a Miracle, Let’s Not Ruin It
GLP-1s are helping Americans live better, but Washington has major work to do on safety. A lot has been happening this fall with the rocket ship rise of GLP-1 weight loss drugs. In September, the Food and Drug Administration announced a “green list” to stop the importation of counterfeit GLP-1 active pharmaceutical ingredients into the U.S., and then came news of Costco partnering with Novo […]