GLP-1 and amylin receptor multiagonism with amycretin for obesity management
Publication date: Available online 20 June 2025 Source: The Lancet Author(s): Bernard Khoo, Tricia M-M Tan
Safety, tolerability, pharmacokinetics, and pharmacodynamics of the first-in-class GLP-1 and amylin receptor agonist, amycretin: a first-in-human, phase 1, double-blind, randomised, placebo-controlled trial
Publication date: Available online 20 June 2025 Source: The Lancet Author(s): Agnes Gasiorek, Arne Heydorn, Sanaz Gabery, Julie B Hjerpsted, Katrine Kirkeby, Thomas Kruse, Signe B Petersen, Søren Toubro, Andreas Vegge, Cassandra Key
Amycretin, a novel, unimolecular GLP-1 and amylin receptor agonist administered subcutaneously: results from a phase 1b/2a randomised controlled study
Publication date: Available online 20 June 2025 Source: The Lancet Author(s): Kirsten Dahl, Søren Toubro, Sohan Dey, Ruben Duque do Vale, Anne Flint, Agnes Gasiorek, Arne Heydorn, Ania M Jastreboff, Cassandra Key, Signe Beck Petersen, Andreas Vegge, Kasper Adelborg
Novo is not dead yet! Novo Nordisk’s experimental drug results in up to 24% weight loss
June 20 (Reuters) – Novo Nordisk (NOVOb.CO) On Friday said full results from early-stage trials show that its experimental drug, amycretin, helped overweight and obese adults lose up to 24% of their weight as the Danish company readies for late-stage studies to start next year. The company said side effects of the drug, tested as both a […]
Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s – wired.com
Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s wired.com Lilly’s oral GLP-1, orforglipron, showed compelling efficacy and a safety profile consistent with injectable GLP-1 medicines, in complete Phase 3 results published in The New England Journal of Medicine Eli Lilly Lilly expects orforglipron obesity results in third quarter Reuters Lilly Obesity Pill to Rival […]
New ‘Ozempic pill’ is better than ‘skinny jabs’ and helps you lose weight even faster, study suggests
PAFile photo dated 15/07/14 of a young child is weighed on scales. A new weight loss medication, which can be offered by injection or tablet, can help patients lose a significant amount weight, studies suggest. An early study have found that people who received higher doses of amycretin as a weekly jab lost 24.3% of […]
Novo Nordisk: Ignored GLP-1 Leader Is Now A Deep Value Play
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Novo Nordisk: Ignored GLP-1 Leader Is Now A Deep Value Play
Let’s Settle This: Is Psyllium Husk Really ‘Nature’s Ozempic’?
psyllium husk GI surgeon Dr Karan Rajan seems pretty fond of psyllium husk. In a video posted last year, he extolled the virtues of the cheap, soluble fibre-rich supplement, explaining it can help to cure both constipation and diarrhoea. It is also, he added, pointing to this 2021 review of studies, “useful in some types of IBS.” […]
Diabetes drug cuts migraines in half by targeting brain pressure
A common diabetes drug may be the next big thing for migraine relief. In a clinical study, obese patients with chronic migraines who took liraglutide, a GLP-1 receptor agonist, experienced over 50% fewer headache days and significantly improved daily functioning without meaningful weight loss. Researchers believe the drug s ability to lower brain fluid pressure […]