Incretin Therapy: Bane Or Boon To Weight Loss

At a time when both international and domestic celebrities like Oprah Winfrey, Elon Musk, Rebel Wilson, Tracey Morgan, filmmakers Hansal Mehta and Karan Johar, plus star actors NTR Junior and Priyanka Chopra Jonas are becoming a talking point for their rapidly visible weight-loss programmes, speculations are rife over how they are pursuing their kilo-shedding goals. […]

The Overlooked Connection Between GLP-1s, Obesity, and Eating Disorders

Gretchen Zimmermann, MBA, RD, VP of Clinical Strategy at Vida Health The false belief that people with obesity do not have eating disorders is one of the most harmful misconceptions in obesity care. In reality, individuals with obesity are at a high risk for eating disorders.  The intersection of obesity, mental health, and disordered eating […]

The GLP-1 receptor agonist liraglutide inhibits necroptosis and neuroinflammation in a mouse model of Parkinson’s disease with diabetes co-morbidity

ObjectiveTo investigate the effects of the glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide on motor function, necroptosis, and neuroinflammation in the brain in mice with diabetic Parkinson’s disease (PD) and its possible mechanism.MethodsWe prepared a diabetic model with streptozotocin, followed by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced diabetic PD model, along with liraglutide or saline intervention, and the control group with […]

Bariatric surgery leads to greater weight loss than GLP-1 drugs after two years

Sleeve gastrectomy and gastric bypass were associated with about five-times more weight loss than weekly injections of GLP-1 receptor agonists semaglutide or tirzepatide, at the end of two years, according to a new head-to-head real-world study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting.

Psychiatric disorders less likely after weight-loss surgery than treatment with GLP-1s

People who have metabolic and bariatric surgery are significantly less likely to develop psychiatric disorders compared to those who take weekly injections of GLP-1 anti-obesity medications, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting. Over a five-year period, the risk of developing […]