Ozempic-maker Novo Nordisk struggles as GLP-1 drugs continue to dominate medicine, culture

The FDA criticized the maker of Ozempic and Wegovy, Novo Nordisk, for “serious violations” related to the reporting of possible side effects linked to semaglutide, the active ingredient in the drug. NBC News’ Emily Lorsch reports on the GLP-1 drugs.
FDA Warns GLP-1 Maker Over Failure to Properly Report Deaths, Strokes

(MedPage Today) — The FDA issued a warning letter to Novo Nordisk for failing to report and investigate potentially serious side effects associated with its popular GLP-1 medications.
In a letter dated March 5 and made public on Tuesday, the…
GLP-1 Drugs May Benefit Cancer Patients With Brain Lesions

(MedPage Today) — GLP-1 receptor agonist use was associated with a lower risk of death in cancer patients with brain metastases and type 2 diabetes, a retrospective cohort study found.
Within 3 years of a first recorded brain metastasis, patients…
Wegovy May Have Higher Risk of ‘Eye Stroke,’ Vision Loss Than Ozempic

Researchers believe that high doses of semaglutide may reduce blood flow to the optic nerve, which could lead to eye stroke. Maria Korneeva/Getty Images
A new study has found that the GLP-1 drug Wegovy is linked with a higher risk of “eye stroke,” especially in men.
Q&A: How small steps can help GLP-1 users build healthier habits

A Stanford study shows simple digital prompts can motivate people taking GLP-1 medications to make lifestyle changes. It’s a simple premise: What if something as small as a digital nudge could put someone on the path to healthier habits while taking GLP-1 medications?
GLP-1 Receptor Agonists Similarly Effective Across Age, Race, Starting Weight

WEDNESDAY, March 11, 2026 — Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for weight loss appear to be similarly effective among adults across ages, races, and starting weights, according to a review published online March 2 in JAMA…
Lilly plots GLP-1 pill production boost in China, $500M pledge to South Korea

Eli Lilly is making moves in East Asia.
The Indianapolis drugmaker said Wednesday it is earmarking $3 billion over the next decade to increase its manufacturing footprint in China. Earlier this …
FDA Warns Novo Nordisk of Unreported GLP-1 Side Effects

The FDA has issued a warning letter to Novo Nordisk saying the maker of Ozempic and Wegovy failed to report potential side effects in patients who took the medications. The agency cited three deaths among patients, including one who died by suicide. The FDA says the company did not report the deaths within the agency’s required time and that it also failed to investigate or report the suicide.
Novo Hit With FDA Warning Letter for Unreported Ozempic Safety Signals

Among the unreported adverse events potentially linked to Ozempic are two deaths and one case of “completed suicide,” according to an FDA inspection report.
GLP-1 medication changes may support long-term weight management

Patients without diabetes who switched GLP-1 receptor agonist (GLP-1RA) drugs for overweight or obesity were more likely to stick with their treatment longer than those who didn’t switch, according to a new study by UT Southwestern Medical Center researchers. The findings, published in JAMA Network Open, suggest that medication changes are not uncommon among patients undergoing weight loss and that clinicians should encourage them to change GLP-1RAs if necessary to promote continuity of care.