A systematic review and meta-analysis on GLP-1 receptor agonists for obesity without diabetes found that they are generally not cost-effective versus other interventions (lifestyle change, surgery)

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$ISRG – Deciphering the Durability of a Surgical Revolution

$ISRG – Deciphering the Durability of a Surgical Revolution Intuitive Surgical, Inc. BATS:ISRG KalaGhazi Intuitive Surgical, Inc. (NASDAQ: ISRG) stands at a critical inflection point in its corporate narrative. The company’s third-quarter 2025 results, headlined by a robust 20% year-over-year growth in combined da Vinci and Ion procedures, have reignited a fundamental debate among investors: […]
Year Ender 2025 Special: From ‘Japanese Walking’ to ‘Oatzempic’, fitness and diet trends that broke the internet

In 2025, fitness and eating habits shifted towards long-term health. Japanese walking, Hyrox-style races, and power training became widely popular. AI trainers and fitness festivals began to replace traditional gym routines. Diet trends focused on fibre, gut health, and GLP-1 companion eating, while “swicy” flavours and fermented foods ruled kitchen trends. Overall, the year marked […]
How weight loss drugs are changing what Americans buy

New research from Cornell University reveals that GLP-1 weight-loss medications are significantly altering American shopping habits. Within six months of starting these drugs, individuals reduced grocery spending by an average of 5.3%, with higher-income households seeing over an 8% drop. Spending at fast-food and coffee shops also fell by approximately 8%.
Is ISRG’s 20% Procedure Growth the New Normal or a Peak?

Intuitive Surgical’s ISRG third-quarter results reignited the long-running debate around the durability of its growth engine. Combined da Vinci and Ion procedures rose 20% year over year in the third quarter of 2025, accelerating from roughly 18% growth in the first half. The top-line number is impressive — but the key investor question is whether […]
Weekend reading: How GLP-1 drugs are affecting food companies

Alert to readers: Amazon.com displays listings for several more workbooks, study guides, and cookbooks purportedly based on my book, What to Eat Now (see previous post on this). I did not write any of them. Caveat emptor! ___________________________ I’ve been collecting items on the effects of GLP-1 drugs on the food industry. Recall my mantra: Eating […]
GLP-1 weight loss meds lead to changes in consumer food demand – study
Weight-loss Pill Approval Set to Accelerate Food Industry Product Overhauls

Packaged food makers and fast-food restaurants may be forced to overhaul more of their products next year as newly approved, appetite-suppressing GLP-1 pills become… Reuters Health Information
Healthcare, Vol. 14, Pages 60: 12-Month Weight Loss and Adherence Predictors in a Real-World UK Tirzepatide-Supported Digital Obesity Service: A Retrospective Cohort Analysis

Healthcare, Vol. 14, Pages 60: 12-Month Weight Loss and Adherence Predictors in a Real-World UK Tirzepatide-Supported Digital Obesity Service: A Retrospective Cohort Analysis Healthcare doi: 10.3390/healthcare14010060 Authors: Louis Talay Jason Hom Tamara Scott Neera Ahuja Background: Obesity management is evolving with the integration of dual GIP/GLP-1 receptor agonists (Tirzepatide) into comprehensive Digital Weight-Loss Services (DWLSs). […]
Marriage and Sex in the Age of Ozempic: An Update

This week, The Daily is revisiting some of our favorite episodes of the year and checking in on what has happened in the time since. In the past few years, GLP-1 weight-loss drugs like Ozempic and Zepbound have been radically reshaping the people’s lives, changing appetites and health. But the drugs also have the power […]