Study: GLP-1RAs associated with less risk of mental illness getting worse
In a sea of uncertainty, a large-scale, long-term Swedish study is the first to show that people using GLP-1 receptor agonists are less likely to have worsening mental illness. The study involved a national cohort of 95,490 people diagnosed with depression or anxiety disorder, who also were treated with any diabetes drug (apart from insulin).
Triple crown: T2D purse for Lilly’s phase III retatrutide?
Further weight loss details are yet to come this year, but Eli Lilly and Co. scored positive top-line results in Transcend-T2D-1, a phase III trial evaluating the efficacy and safety of retatrutide, an investigational first-in-class GIP, GLP-1 and glucagon triple hormone receptor agonist, as an adjunct to diet and exercise in type 2 diabetes (T2D).
Lilly’s triple-G lags Mounjaro on blood sugar lowering, first Phase 3 diabetes data suggest
Eli Lilly’s so-called triple-G reduced blood sugar levels in patients with type 2 diabetes by up to 1.9% in a late-stage trial — a slightly lower margin than Mounjaro achieved in its pivotal diabetes study.
The …
Ozempic Is About to Go Generic in India, China and Canada
In India, China and several other nations, Novo Nordisk is on the verge of losing patent protection for its blockbuster weight loss drug, opening the door for cheaper competing versions.
GLP-1 diabetes drugs could stop anxiety and depression worsening, study finds
Drugs such as semaglutide may be useful for mental health conditions associated with diabetes, authors sayDiabetes drugs could prevent anxiety and depression from worsening, according to research.Type 2 diabetes affects more than 800 million people globally and research shows that those with the condition are about twice as likely to have depression as the wider population. Continue reading…
GLP-1 medications used to treat diabetes and obesity may also help alleviate symptoms of anxiety and depression
GLP-1 medications used to treat diabetes and obesity were associated with a reduced need for hospital care and sickness absence due to psychiatric reasons, a new study shows. The large register-based study was carried out in collaboration between the University of Eastern Finland, Karolinska Institutet in Stockholm and Griffith University in Australia.
The Unexpected Mental Health Effect of GLP-1 Medications
The study findings may spark treatment innovations for depression and anxiety.
Ozempic in Schizophrenia; Psychiatrist Talks Euthanasia; New Opioid Threat
(MedPage Today) — In overweight, prediabetic schizophrenia patients on second-generation antipsychotics, semaglutide (Ozempic) significantly improved insulin sensitivity, fasting glucose, and weight. (Diabetes Care)
Experts weighed in on whether…
Stopping Ozempic? New study reveals surprising weight regain results after GLP-1s
New research challenges fears about Ozempic weight regain. Cleveland Clinic study of 8,000 patients finds minimal rebound after stopping GLP-1 medications.
Stopping GLP-1 drugs can quickly erase cardiovascular benefits
Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular benefits. However, when patients stop taking these drugs, they not only regain weight, but, according to a new study, they also incur increased risk of heart attack, stroke, and death compared to staying on the medication.