Development and validation of an LC-MS/MS method for Tirzepatide, a dual GIP/GLP-1 receptor agonist, in rat plasma for application to a pharmacokinetic study
Publication date: Available online 26 October 2025 Source: Journal of Chromatography B Author(s): Hae-In Choi, Hyeon-Cheol Jeong, Jong-Woo Jeong, Jaeyoung Lee, Da Hae Kim, Kyong-Cheol Ko, Yoon-Jee Chae, Kyeong-Ryoon Lee
Inside Sherwood: Covering healthcare, GLP-1s and the stories that matter to retail investors
How a disruptive media outlet thinks about pitches. Amanda Coffee is CEO of Coffee Communications and ex-Under Armour, PayPal and eBay. Sherwood is one of the newest players in business journalism, operating as the editorially independent news arm of Robinhood. With a mission to deliver finance and business news tailored to a retail investor audience, Sherwood […]
Tirzepatide-Hormone Therapy Combo Tied to Weight Loss in Postmenopausal Women
(MedPage Today) — ORLANDO — Postmenopausal women using hormone therapy (HT) saw significantly greater weight loss while taking the dual GIP/GLP-1 receptor agonist tirzepatide than their counterparts not using HT, according to a retrospective…
Weight-loss drugs like Ozempic may also curb drug and alcohol addiction
GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, and nicotine use. Though more research is needed, scientists believe these drugs could open a powerful new front in addiction therapy.
Popular weight-loss drugs could take the edge off your alcohol buzz, study finds
Popular drugs credited with shrinking waistlines and controlling blood sugar may also take the edge off alcohol’s buzz, according to a new study. Researchers at Virginia Tech’s Fralin Biomedical Research Institute analyzed how 20 adults with obesity — half of whom had been taking GLP-1 receptor agonists for at least four weeks — reacted to […]
What a Diabetes Diagnosis Taught Me About MAHA
Photo: Andrew Burke-Stevenson/Boston Globe/Getty Images One morning in late September, I drank a cup of coffee without sugar and ate half an English muffin for breakfast. Boring choices, but I like routines; I always drink coffee in the morning, and I always drink it with some milk. If I eat breakfast, I don’t eat much. […]
5 Ways To Reduce Hunger & Cravings By Promoting Natural GLP-1 Production
Numbers 1 & 2 are a must.
Eating less protein could help you live longer. Here’s how
The idea that eating less might make us live longer has been around for thousands of years. Even Hippocrates, the Ancient Greek physician, argued that, “When a patient is fed too richly, the disease is fed as well. Any excess is against nature.” Scientists have now spent decades testing whether his advice holds true. The […]
Health insurance for a family through a job hits $27,000 a year — the cost of a new Toyota Corolla hybrid
More than 154 million people with health insurance through an employer face steep price increases, and the situation is likely to get worse, a new report shows. The increases are coming as the federal government shutdown has been spurred by a stalemate over health insurance for another group, the 22 million Americans on Affordable Care […]
What’s next after GLP-1?
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