Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice

Glucagon-like peptide-1 receptor (GLP-1R) activation in the brain strongly reduces appetite, but most brain GLP-1Rs are not accessible for systemically administered GLP-1R agonists. Acute activation of nucleus tractus solitarius (NTS) GLP-1 neurons, targeting brain GLP-1Rs, strongly suppresses food intake separate from GLP-1R agonists. However, it is unknown if their chronic stimulation is a viable strategy […]

Doctors call Ozempic a miracle drug. Medicaid officials aren’t so sure.

Breakthroughs in weight-loss medicine are presenting state Medicaid officials with what looks like a sure bet: Spend big now to cover the drugs and reap savings when diabetes, heart disease and cancer rates drop. States are hesitating to take it. The few states that have decided to cover drugs like Ozempic and Wegovy to help […]

Nutrients, Vol. 17, Pages 3778: Consuming Tree Nuts Daily as Between-Meal Snacks Reduces Food Cravings and Improves Diet Quality in American Young Adults at High Metabolic Syndrome Risk

Nutrients, Vol. 17, Pages 3778: Consuming Tree Nuts Daily as Between-Meal Snacks Reduces Food Cravings and Improves Diet Quality in American Young Adults at High Metabolic Syndrome Risk Nutrients doi: 10.3390/nu17233778 Authors: Kate Lillegard Annaliese Widmer John R. Koethe Heidi J. Silver Background: Daily energy intake from snacking behaviors has increased over the past few […]

Obesities, Vol. 5, Pages 88: Nutritional Approaches to Enhance GLP-1 Analogue Therapy in Obesity: A Narrative Review

Obesities, Vol. 5, Pages 88: Nutritional Approaches to Enhance GLP-1 Analogue Therapy in Obesity: A Narrative Review Obesities doi: 10.3390/obesities5040088 Authors: Denise Deo Dias Andrea Rodrigues Vasconcelos Ana Carolina Remondi Souza Caroline de Menezes Isabella Sobral Teixeira e Silva José João Name Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are highly effective in the management of obesity; […]