Bone Fractures Down With GLP-1 Drugs in the Picture
(MedPage Today) — Beyond their established cardiometabolic benefits, GLP-1 receptor agonists also may be tied to improved bone health, based on an observational report. Adults with type 2 diabetes on GLP-1 agonists tended to have small but significant…
GLP-1 Receptor Agonists May Have Little or No Effect on Obesity-Related Cancers
WEDNESDAY, Dec. 10, 2025 — Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) seem to have little or no effect on obesity-related cancers, according to a review published online Dec. 8 in the Annals of Internal Medicine. Albert Ko, M.D., from…
Can NVO Defend Its Obesity Lead as GLP-1 Competition Intensifies?
Novo Nordisk NVO is a dominant player in the cardiometabolic space, marketing its blockbuster semaglutide-based (GLP-1) drugs — Ozempic (for diabetes) and Wegovy (for obesity). Despite being NVO’s key growth drivers, sales momentum for both drugs has slowed in recent quarters due to pricing pressure, intensifying GLP-1 competition from Eli Lilly LLY, foreign exchange headwinds, and […]
Pharmaceutics, Vol. 17, Pages 1596: Oral Treatment of Obesity by GLP-1 and Its Analogs
Pharmaceutics, Vol. 17, Pages 1596: Oral Treatment of Obesity by GLP-1 and Its Analogs Pharmaceutics doi: 10.3390/pharmaceutics17121596 Authors: Natasa Holler Ivana Ruseska Anna-Laurence Schachner-Nedherer Andreas Zimmer Christina Petschacher Obesity is a multifaceted disease that significantly increases the risk of various chronic conditions. GLP-1R (co)-agonists first emerged as therapeutics for treatment of type 2 diabetes mellitus […]
Can GLP-1 help with PCOS symptoms? What the weight-loss drugs may mean for women’s treatment.
GLP-1 usage is on the rise, and researchers are looking for other health benefits associated with the drug, including its effects on PCOS. Polycystic ovarian syndrome, or PCOS, is a hormonal disorder that can cause irregular periods, excessive hair growth, excessive acne and fertility issues. Sign up for our newsletter for the day’s top stories, […]
Antioxidants, Vol. 14, Pages 1484: BiombalanceTM: A Specific Oligomeric Procyanidin-Rich Grape Seed Extract as Multifunctional Ingredient Integrating Antibacterial, Antioxidant, and Anti-Inflammatory Activities with Beneficial Gut–Brain Axis Modulation
Antioxidants, Vol. 14, Pages 1484: BiombalanceTM: A Specific Oligomeric Procyanidin-Rich Grape Seed Extract as Multifunctional Ingredient Integrating Antibacterial, Antioxidant, and Anti-Inflammatory Activities with Beneficial Gut–Brain Axis Modulation Antioxidants doi: 10.3390/antiox14121484 Authors: Mohamed Mokrani Amandine Brochot Maria C. Urdaci Polyphenols, as natural compounds abundant in plant-derived foods, have been recognised for their human health benefits. This […]
Chronic semaglutide treatment enhances the incentive motivational value of a small food reward and associated cue in male and female rats
Rationale: Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide, are increasingly utilized in clinical practice due to their efficacy in promoting sustained weight loss following chronic administration. While acute treatment with GLP-1 receptor agonists has been shown to suppress food intake and reward-seeking behaviors in rodent models, the impact of prolonged exposure on preclinical measures […]
First ever GLP-1 implant for pets promises major weight-loss benefits
The world’s first GLP-1 weight loss treatment is being administered for pets on an experimental basis.
Costs of Cutting Weight—An Economic Evaluation of GLP-1 Agonists vs Gastric Bypass
This economic evaluation compares the long-term cost-effectiveness of glucagon-like peptide-1 (GLP-1) receptor agonists vs Roux-en-Y gastric bypass.
Eli Lilly plans $6B API plant in Alabama
Eli Lilly will build a $6 billion new facility in Huntsville, Ala., to manufacture active pharmaceutical ingredients for small molecule and peptide medicines, including the company’s oral GLP-1 candidate, orforglipron. The site will support domestic production of therapies and strengthen pharmaceutical supply chains, according to a Dec. 9 news release from the drugmaker. The project is […]