Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice

Glucagon-like peptide-1 receptor (GLP-1R) activation in the brain strongly reduces appetite, but most brain GLP-1Rs are not accessible for systemically administered GLP-1R agonists. Acute activation of nucleus tractus solitarius (NTS) GLP-1 neurons, targeting brain GLP-1Rs, strongly suppresses food intake separate from GLP-1R agonists. However, it is unknown if their chronic stimulation is a viable strategy […]
WHO calls for ‘responsible use’ of GLP-1 drugs for long term obesity care

The guideline reframes obesity as a chronic disease needing lifelong care, recommending GLP-1 therapies with behavioural support rather than relying on medication alone
Will blockbuster obesity drugs revolutionize addiction treatment?

Nature, Published online: 02 December 2025; doi:10.1038/d41586-025-03911-x Scientists are testing whether GLP-1 drugs can help to cut cravings for cigarettes, alcohol and opioids — as well as food.
Could Weight Loss Drugs Turn Fat Cats Into Svelte Ozempets?

GLP-1 drugs for pets could be the next frontier for the blockbuster weight loss and diabetes drugs.
Doctors call Ozempic a miracle drug. Medicaid officials aren’t so sure.

Breakthroughs in weight-loss medicine are presenting state Medicaid officials with what looks like a sure bet: Spend big now to cover the drugs and reap savings when diabetes, heart disease and cancer rates drop. States are hesitating to take it. The few states that have decided to cover drugs like Ozempic and Wegovy to help […]
Nutrients, Vol. 17, Pages 3778: Consuming Tree Nuts Daily as Between-Meal Snacks Reduces Food Cravings and Improves Diet Quality in American Young Adults at High Metabolic Syndrome Risk

Nutrients, Vol. 17, Pages 3778: Consuming Tree Nuts Daily as Between-Meal Snacks Reduces Food Cravings and Improves Diet Quality in American Young Adults at High Metabolic Syndrome Risk Nutrients doi: 10.3390/nu17233778 Authors: Kate Lillegard Annaliese Widmer John R. Koethe Heidi J. Silver Background: Daily energy intake from snacking behaviors has increased over the past few […]
Obesities, Vol. 5, Pages 88: Nutritional Approaches to Enhance GLP-1 Analogue Therapy in Obesity: A Narrative Review

Obesities, Vol. 5, Pages 88: Nutritional Approaches to Enhance GLP-1 Analogue Therapy in Obesity: A Narrative Review Obesities doi: 10.3390/obesities5040088 Authors: Denise Deo Dias Andrea Rodrigues Vasconcelos Ana Carolina Remondi Souza Caroline de Menezes Isabella Sobral Teixeira e Silva José João Name Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are highly effective in the management of obesity; […]
Metropolis launches GLP-1 monitoring test packages, targets obesity market

Metropolis Healthcare has rolled out three TruHealth GLP-1 test packages for patients preparing for or undergoing obesity treatment, as diagnostics firms move to tap the fast-growing segment
UPSC Key: Sanchar Saathi app, GPS ‘spoofing’, and WHO guidelines on use of GLP-1

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Overlooked hormone may be deadly driver of postmenopausal breast cancer in women with obesity

A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in postmenopausal women with obesity. It also raises the possibility that treatment of these aggressive breast cancers could be improved with the addition […]