Defining Clinical Obesity
Definition and diagnostic criteria of clinical obesityRubino, Francesco et al.The Lancet Diabetes & Endocrinology, Volume 13, Issue 3, 221 – 262 The Lancet Diabetes & Endocrinology Commission’s comprehensive work on defining and diagnosing clinical obesity, distinguishing it from mere excess adiposity. A large international expert group, including patient representatives, utilized a Delphi-like consensus process to establish objective criteria for clinical obesity in […]
CPAP Or Zepbound? Patients, Doctors Debate Sleep Apnea Treatment
MONDAY, June 9, 2025 — A clash is brewing between doctors and patients when it comes to treatment for sleep apnea in those with obesity, a new study reports.Doctors favor treatment with continuous positive airway pressure (CPAP) machines, r…
CPAP Or Zepbound? Patients, Doctors Debate Sleep Apnea Treatment
MONDAY, June 9, 2025 — A clash is brewing between doctors and patients when it comes to treatment for sleep apnea in those with obesity, a new study reports.
Doctors favor treatment with continuous positive airway pressure (CPAP) machines…
The golden era of GLP-1 drugs: How will it impact medicine and society?
GLP-1 drugs are transforming medicine, but what are the medical and societal ripple effects?
Most Favored Nation Drug Pricing Will Flop, but What Wouldn’t?
Politics Most Favored Nation Drug Pricing Will Flop, but What Wouldn’t? Pursuing the worthy goal of reforming drug pricing requires a more radical change to the pharmaceutical industry. On May 12, President Trump took a big swing at cutting drug prices, issuing an executive order requiring Most Favored Nation (MFN) pricing, resetting U.S. drug prices […]
Oprah Winfrey is thinner than ever in black gown at Tony Awards after Ozempic makeover
The 71-year-old OWN CEO finally reached her 160lb goal weight in 2023 with help from an unnamed GLP-1 agonist drug after undergoing double-knee replacement surgery in 2021
An effective treatment using an effective care delivery model: Using telehealth to treat adolescents with obesity with GLP-1 medications
Will a telehealth model effectively engage adolescents with obesity and their parents to participate in their treatment plan? Do GLP-1 agonist medications work to improve weight status and reduce or eliminate comorbidities in adolescents? I’ve worked for over two decades as a community pediatrician to address the childhood and adolescent obesity epidemic. I can say […]
The Drivers of Age-Related Diseases
We’ve known that our immune system and the process of inflammation are tightly intertwined and are affected by aging. The terms immunosenescence and inflammaging have been coined to reflect that. In the past few weeks there have been a number of important publications that tell us much more about their pivotal role for influencing the […]
ClinicalTrials.gov – Who, what, when, and where.
ClinicalTrials.gov is a public database maintained by the U.S. National Library of Medicine (NLM) at the National Institutes of Health (NIH). It provides detailed information about clinical studies involving human participants, conducted worldwide. Key Features:Registry: Researchers and sponsors (such as pharmaceutical companies, academic institutions, and government agencies) are required or encouraged to register their clinical […]
Beyond MAHA: Defeating obesity requires a new strategy
Obesity is a major health problem facing our country. According to the CDC, more than 40 percent of the U.S. population is obese, defined as having a body-mass index above 30. As astounding at that number is, it is perhaps even more surprising that nearly 20 percent of children in the U.S. are obese. Obesity leads […]