Use of Obesity Drugs in Cancer Patients Increases Despite Lack of Clinical Guidance
(MedPage Today) — Prescriptions for GLP-1 receptor agonists for patients with cancer have increased despite a lack of clinical guidance on the drugs’ safety and efficacy in cancer, a large retrospective review of health records showed. Overall…
STAT+: Patient with liver damage in Intellia trial dies
This is the online version of Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up here to get it delivered to their inbox. Morning! Lots in biotech today…. New priority review vouchers from the FDA, Mark Cuban rolls out a biosimilar deal, and a patient death is reported in Intellia’s CRISPR trial. Trump’s priority review vouchers […]
Stephen Colbert Mocks Trump’s ‘Viral’ Reaction to Pharma Exec Fainting at Presser: ‘Worth a Thousand Words’
The Late Show host Stephen Colbert mused that “almost everybody” dashed to help a Big Pharma exec who fainted during a drug pricing reform presser at the Oval Office, seizing on a still photo of President Donald Trump’s reaction that he said was “worth a thousand words.” During the Oval Office event Thursday, as the […]
Does Microdosing GLP-1s Work? Expert Weighs In
(MedPage Today) — Welcome to Culture Clinic, MedPage Today’s collaboration with Northwell Health to offer a healthcare professional’s take on the latest viral medical topics. More companies are promoting microdosing GLP-1 receptor agonists even…
Peptides on Tap: Automated Flow Synthesis with Standard HPLC
Peptide synthesis is central to biomedical research, yet automated flow synthesis typically requires custom-built instrumentation, limiting accessibility beyond specialized laboratories. Here we demonstrate that a standard analytical HPLC can be repurposed for fully automated flow-based peptide synthesis. By packing a short guard column with resin and programming reagent injections through the autosampler, we achieved efficient […]
GI Safety Profile Similar for Dulaglutide, Semaglutide, Tirzepatide
FRIDAY, Nov. 7, 2025 — For patients with type 2 diabetes (T2D), the gastrointestinal safety profile is similar for dulaglutide, semaglutide, and tirzepatide, according to a study published online Nov. 4 in the Annals of Internal Medicine.Salvatore…
Duodenal Mucosal Resurfacing Curbs Weight Gain Post-GLP-1
The investigational endoscopic procedure may help patients maintain weight loss or lose more weight 3 months after GLP-1 receptor agonist therapy discontinuation. Medscape Medical News
How much do popular obesity drugs cost?
Popular weight loss drugs like Wegovy and Zepbound will soon cost Americans less under a new deal announced by President Donald Trump on Thursday. Agreements with drugmakers Novo Nordisk and Eli Lilly will slash the prices of so-called GLP-1 drugs, which could eventually cost as little as $149 per month. The average price of the […]
JCM, Vol. 14, Pages 7910: Beyond Lipids and Platelets: A Review of Anti-Inflammatory Strategies in Secondary Prevention of Acute Coronary Syndromes
JCM, Vol. 14, Pages 7910: Beyond Lipids and Platelets: A Review of Anti-Inflammatory Strategies in Secondary Prevention of Acute Coronary Syndromes Journal of Clinical Medicine doi: 10.3390/jcm14227910 Authors: Girish Pathangey Mohamed N. Allam Mahmoud H. Abdelnabi Dan Sorajja Floyd David Fortuin Kwan S. Lee Mayurkumar D. Bhakta Despite advances in lipid-lowering and antithrombotic therapy, patients […]
The Pros and Cons of Ozempic
Hank Green of SciShow looked at increasingly popular Semaglutide medications such as Ozempic and Wegovy, and explained both the pros and the cons of these GLP-1 agonists on the human body. Pros include weight loss, blood sugar control, and heart and brain function improvement. Cons include gastrointestinal distress, birth control nullification, vision problems, and conflicting information regarding […]