GLP-1 drugs may be linked to elevated risk of serious eye disease, study finds – statnews.com

GLP-1 drugs may be linked to elevated risk of serious eye disease, study finds  statnews.com Weight loss drugs linked to higher risk of eye damage in diabetic patients  The Guardian GLP-1 RAs Linked to Doubled Risk for Macular Degeneration  Medscape Semaglutide Linked to Age-Related Macular Degeneration Risk  MedPage Today Study Links GLP-1 Drugs to Increased Risk of Diabetic Retinopathy […]

Agency warns that weight loss drugs can decrease effectiveness of birth control pills

Anecdotes abound about “Ozempic babies”—when women wound up with unplanned pregnancies while taking both birth-control and the popular GLP-1 drugs for diabetes or weight loss.  But today marks the first official agency warning about the possibility of these drugs—specifically Mounjaro—decreasing the effectiveness of oral contraceptives. “Women taking popular medicines for weight loss and diabetes, sometimes […]

GLP-1 drugs may be linked to elevated risk of serious eye disease, study finds

People with diabetes who were taking GLP-1 drugs had a low but elevated risk of an age-related eye disease that can sometimes lead to blindness, a new observational study concludes, adding to a short list of concerns about eye health in people taking the powerful medications. The research, published Thursday in JAMA Ophthalmology, found that […]

What is “Enforcement Discretion” (FDA context)?

Enforcement discretion means that a regulatory agency like the FDA (U.S. Food and Drug Administration) chooses not to enforce certain rules or regulations under specific circumstances, even if technically a violation has occurred. This is often done:• To avoid disrupting access to critical healthcare (e.g., during emergencies like COVID-19).• When the agency believes that the […]

Retatrutide: A Triple Agonist for Diabetes and Obesity

Abdul-Rahman T, Roy P, Ahmed FK, Mueller-Gomez JL, Sarkar S, Garg N, Femi-Lawal VO, Wireko AA, Thaalibi HI, Hashmi MU, Dzebu AS, Banimusa SB, Sood A. The power of three: Retatrutide’s role in modern obesity and diabetes therapy. Eur J Pharmacol. 2024 Dec 15;985:177095. doi: 10.1016/j.ejphar.2024.177095. Epub 2024 Nov 6. PMID: 39515565. Comprehensive narrative review focusing on retatrutide, […]

The “summer body” is over. Something worse is taking its place. 

Women in bathing suits lined up on the beach in 1949. | FPG/Getty Images For decades, women have heard about the mythical “summer body” — toned arms, ripped abs, no cellulite. Some people also call this narrow goal “bathing suit ready,” or talk about having a “beach body.” In the months leading up to the […]

Q&A: Long-term success of GLP-1 therapies hinges on more than just a prescription

GLP-1 (glucagon-like peptide-1) therapies can be powerful tools in managing obesity, with patients taking these medications seeing weight reductions of 5%–18% in clinical trials, along with increased metabolism and benefits to their overall heart health. However, GLP-1s can come with challenges, including gastrointestinal side effects, risk of micronutrient deficiencies, muscle and bone loss, poor long-term […]

Weight loss drugs could make oral contraception less effective, MHRA warns

Women who take weight loss drugs should use barrier contraception if they are seeking to avoid pregnancy, the medicines regulator has advised.The Medicines and Healthcare Products Regulatory Agency has issued guidance warning that the drugs could reduce the effectiveness of oral contraceptives.1 The agency said it had received reports of 40 pregnancy related adverse events […]