Weight loss drugs linked to higher risk of eye damage in diabetic patients

Study finds medicines such as Ozempic associated with greater risk of developing age-related macular degeneration Weight loss drugs could at least double the risk of diabetic patients developing age-related macular degeneration, a large-scale study has found. Originally developed for diabetes patients, glucagon-like peptide-1 receptor agonist (GLP-1 RA) medicines have transformed how obesity is treated and […]
GLP-1 drugs may be linked to elevated risk of serious eye disease, study finds – statnews.com

GLP-1 drugs may be linked to elevated risk of serious eye disease, study finds statnews.com Weight loss drugs linked to higher risk of eye damage in diabetic patients The Guardian GLP-1 RAs Linked to Doubled Risk for Macular Degeneration Medscape Semaglutide Linked to Age-Related Macular Degeneration Risk MedPage Today Study Links GLP-1 Drugs to Increased Risk of Diabetic Retinopathy […]
Agency warns that weight loss drugs can decrease effectiveness of birth control pills

Anecdotes abound about “Ozempic babies”—when women wound up with unplanned pregnancies while taking both birth-control and the popular GLP-1 drugs for diabetes or weight loss. But today marks the first official agency warning about the possibility of these drugs—specifically Mounjaro—decreasing the effectiveness of oral contraceptives. “Women taking popular medicines for weight loss and diabetes, sometimes […]
Dry mouth, bad breath and tooth damage: The effects Ozempic and Wegovy can have on your mouth

Ozempic and Wegovy have been hailed as wonder drugs when it comes to weight loss. But as the drug has become more widely used, a number of unintended side-effects have become apparent—with the weight loss drug affecting the appearance of everything from your butt to your feet.
GLP-1 drugs may be linked to elevated risk of serious eye disease, study finds

People with diabetes who were taking GLP-1 drugs had a low but elevated risk of an age-related eye disease that can sometimes lead to blindness, a new observational study concludes, adding to a short list of concerns about eye health in people taking the powerful medications. The research, published Thursday in JAMA Ophthalmology, found that […]
MHRA Urges Contraception With GLP-1 Weight-Loss Drugs

Women using GLP-1 weight-loss drugs must use effective contraception, the MHRA has warned, citing unknown risks to pregnancy and foetal health. Medscape News UK
What is “Enforcement Discretion” (FDA context)?

Enforcement discretion means that a regulatory agency like the FDA (U.S. Food and Drug Administration) chooses not to enforce certain rules or regulations under specific circumstances, even if technically a violation has occurred. This is often done:• To avoid disrupting access to critical healthcare (e.g., during emergencies like COVID-19).• When the agency believes that the […]
Retatrutide: A Triple Agonist for Diabetes and Obesity

Abdul-Rahman T, Roy P, Ahmed FK, Mueller-Gomez JL, Sarkar S, Garg N, Femi-Lawal VO, Wireko AA, Thaalibi HI, Hashmi MU, Dzebu AS, Banimusa SB, Sood A. The power of three: Retatrutide’s role in modern obesity and diabetes therapy. Eur J Pharmacol. 2024 Dec 15;985:177095. doi: 10.1016/j.ejphar.2024.177095. Epub 2024 Nov 6. PMID: 39515565. Comprehensive narrative review focusing on retatrutide, […]
The “summer body” is over. Something worse is taking its place.

Women in bathing suits lined up on the beach in 1949. | FPG/Getty Images For decades, women have heard about the mythical “summer body” — toned arms, ripped abs, no cellulite. Some people also call this narrow goal “bathing suit ready,” or talk about having a “beach body.” In the months leading up to the […]
Q&A: Long-term success of GLP-1 therapies hinges on more than just a prescription

GLP-1 (glucagon-like peptide-1) therapies can be powerful tools in managing obesity, with patients taking these medications seeing weight reductions of 5%–18% in clinical trials, along with increased metabolism and benefits to their overall heart health. However, GLP-1s can come with challenges, including gastrointestinal side effects, risk of micronutrient deficiencies, muscle and bone loss, poor long-term […]