Below 1,800p, are Diageo shares mispriced?
Diageo (LSE: DGE) shares have more than halved in value in recent years. As a result, they look cheap right now â currently the forward-looking price-to-earnings (P/E) ratio is just 14, falling to 13 using next financial yearâs earnings forecast. That latter multiple’s below the FTSE 100 average. And it begs the question: are the […]
Myostatin Blocker Preserves Muscle With GLP-1 Treatment
Regeneron’s monoclonal antibody trevogrumab, with or without the anti-activin A antibody garetosmab, appears to preserve lean mass and promote fat mass loss. Medscape Medical News
Dom Joly reveals he’s been on fat jabs for a year after weight gain left him at risk of DYING in his sleep
COMEDIAN Dom Joly revealed how the fat jab, Mounjaro, has helped turn his health around. The star of Trigger Happy TV, 57, opened up on how the weekly jab “changed his life” after he was diagnosed with a potentially life-ending disorder. Instagram/@realdomjolyComedian Dom Joly spoke about taking the fat jab, Mounjaro[/caption] TikTok/@russellhowardHe has been taking […]
STAT+: Skye’s obesity drug fails in mid-stage study
Skye Bioscience said Monday that its obesity drug candidate failed to help patients lose significant weight in a mid-stage study, hampering the biotech’s efforts to bring forward a drug with a controversial mechanism. The medicine, an antibody that blocks CB1 receptors, led patients to lose on average 1.5% of their weight over 26 weeks, but […]
Costco to Sell Ozempic and Wegovy, Weight-Loss Wonder Drugs
Costco members will pay $499 a month out of pocket, the same price offered at CVS and Walmart, and on the manufacturer’s direct-to-consumer website.
Serena Williams, Rebel Wilson, Lizzo and the Cost of GLP-1 Honesty
Once upon a time, a famous person might lose weight with alarming speed and say with a straight face that she’d done it by eating a balanced diet of smaller portions. Though we regular folks wanted that to be true — it gave us hope we could follow their simple steps and shrink ourselves — […]
Overeating driven by emotions resists GLP-1 weight loss drugs, study finds
(NaturalNews) New research highlights that weight-loss medications, particularly GLP-1 receptor agonists (GLP-1s), may be less effective for individuals who overeat…
Fight Aging! Newsletter, October 6th 2025
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter, please visit: https://www.fightaging.org/newsletter/. To unsubscribe, send email or reply to […]
I Had My Stomach Stapled At 14 Years Old. That Surgery Didn’t ‘Cure’ Me – Far From It.
Photo of the author, circa 1992, at 12 years old. 285 pounds. Forty-three years old. Summer 2024. “Have you thought about GLPs?” my primary care physician asked as she listened to my heart. I laughed nervously. “No, but I am now.” Humour has always been my shield. She didn’t flinch. “Your BMI is over 40. […]
Metabolic STAMP for deciphering GPCR-regulated insulin secretion by pancreatic β cells
Pancreatic {beta} cells integrate glucose and metabolic cues to regulate insulin secretion, a process disrupted in T2D. GPCRs play a critical role in fine-tuning insulin release, yet the mechanisms by which ciliary (e.g., FFAR4) and non-ciliary (e.g., GLP1-R) GPCRs coordinate GSIS remains unclear. In this study, we employed Metabolic-STAMP (Synchronized Temporal-Spatial Analysis via Microscopy and […]