Metabolic STAMP for deciphering GPCR-regulated insulin secretion by pancreatic β cells
Pancreatic {beta} cells integrate glucose and metabolic cues to regulate insulin secretion, a process disrupted in T2D. GPCRs play a critical role in fine-tuning insulin release, yet the mechanisms by which ciliary (e.g., FFAR4) and non-ciliary (e.g., GLP1-R) GPCRs coordinate GSIS remains unclear. In this study, we employed Metabolic-STAMP (Synchronized Temporal-Spatial Analysis via Microscopy and […]
Novo-Costco GLP-1 deal, Tesla legal heat, OpenAI’s $400B push: This week in markets
GLP-1 price cuts, AI megaspend, and EV headaches headline this week in corporate news. Here are the moves to watch — and why they matter. Week of Oct 5, 2025 News image Novo Nordisk (NVO) + Costco (COST): Wegovy/Ozempic at $499 per month for members; broader access via Walmart, CVS, and GoodRx reinforces US GLP-1 […]
This new semaglutide dose helped nearly half of patients lose 20% body weight
The STEP UP trials revealed that a 7.2 mg dose of semaglutide led to greater weight loss than the currently approved 2.4 mg dose. Nearly half of participants lost 20% or more of their body weight, while also improving metabolic health. Side effects were mostly mild and temporary. Researchers say this could reshape obesity treatment if confirmed in longer-term studies.
Jim Cramer Highlights Eli Lilly’s Drug Potential Beyond Diabetes and Obesity
Eli Lilly and Company (NYSE:LLY) is one of the stocks Jim Cramer put under the microscope. Cramer highlighted the importance of the company’s GLP-1 drug, as he stated: “I suggest, for example, that you consider Eli Lilly because of its remarkable GLP-1 diabetes and weight loss drug. Those are the most obvious uses. But when […]
Costco to sell weight-loss drugs such as Ozempic and Wegovy at half-price
The move comes as GLP-1 drug prices have soared as supply continues to be increasingly limited Costco has struck an agreement with drugmaker Novo Nordisk to make anti-obesity GLP-1 medications such as Ozempic and Wegovy available to its members at roughly half the usual cost. Through the store’s prescription program, members with a valid prescription […]
Considering GLP-1 Agonists for Patients With Psoriasis, HS
Obesity and the proinflammatory state are sufficiently tied to psoriasis and HS that GLP-1 agonists should be considered within multifaceted care, experts say. Medscape Medical News
Costco members will soon have access to weight-loss shots at a major discount
Costco’s latest perk could help shrink members’ waistlines, while having less of an impact on their wallets. The big-box retailer is partnering with Novo Nordisk to give members access to popular GLP-1 medications such as Wegovy and Ozempic at half price. “We are excited to announce our collaboration with [Costco] Pharmacy! Costco members who are […]
I was so terrified of being fat-shamed at size 12 I turned to Mounjaro but one side effect was hell, says Caprice
HER incredible figure has been the envy of women across the world for decades. But now supermodel-turned-filmmaker Caprice Bourret has revealed she was so scared of being trolled after gaining 20lbs that she turned to weight loss drug Mounjaro. Mark HaymanCaprice Bourret says she was so scared of being trolled after gaining 20lbs that she […]
2 overlooked UK shares to consider for dividend income
When it comes to earning passive income from dividends, there are plenty of UK shares offering chunky payouts. But while most investors are drawn to the highest yields or the largest market-caps, plenty of lucrative opportunities get overlooked. That certainly seems to be the case for Hikma Pharmaceuticals (LSE:HIK) and Premier Foods (LSE:PFD), which donât […]
My Digital GLP-1
I needed a digital detox and had a lot of quick success using the BePresent app. I am not an affiliate or connected to the company, just a fan. This new freedom inspired me to write about my journey to hopefully inspire others also trapped in the digital multiverse. Feel free to take a quick […]