GLP-1 prescriptions surge in US: 7 study notes

In 2024, 4% of U.S. adults were prescribed a GLP-1 therapy — a 363.7% increase from 0.9% in 2019, according to a Fair Health analysis of more than 51 billion commercial claim records.  Fair Health also found that, over those six years, the percentage of adults with a GLP-1 prescription for obesity or overweight increased […]

The role of GLP-1 receptor agonists in the management of obesity

As Australia faces a turning point in obesity management, researchers from Monash University have contributed new insights into the rapidly evolving use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) such as Ozempic in the Australian health care system.

Fractyl Rejuva GLP-1 Gene Therapy Data at ASGCT 2025

The sources discuss Fractyl Health’s Rejuva GLP-1 gene therapy platform, highlighting preclinical data presented at ASGCT 2025 for its candidate RJVA-001. This research indicates that a single dose of RJVA-001 in animal models durably improves metabolic markers related to type 2 diabetes and obesity, achieving similar effects as existing GLP-1 drugs but with significantly lower systemic exposure, potentially leading to fewer […]

GLP-1 drugs are life-changing — let’s remove their stigma

I have struggled with my weight my entire life — sometimes less successfully (hello, cooking school in Paris) and sometimes much more successfully. Prior to becoming pregnant, I can’t remember a single time in my life that I wasn’t on a diet or some special workout kick, or whatever it might be. This led me […]

GLP-1 Use and Fatigue

ChatGPTMay 26, 2025 Fatigue or low energy is a commonly reported side effect among users of GLP-1 receptor agonists like semaglutide (Ozempic/Wegovy) or tirzepatide (Mounjaro/Zepbound), but it is not as well characterized or studied as gastrointestinal effects. Here’s what is currently known: 🔍 What We Know About Fatigue and GLP-1 Use ✅ PrevalenceFatigue is reported […]

Study compares Zepbound and Wegovy for weight loss in direct comparison

Weight-loss medications continue to grow in popularity as an anti-obesity tool — but are some more effective than others? The question was explored in a new study published this month in The New England Journal of Medicine. Researchers compared the safety and efficacy of tirzepatide (brand name Zepbound) and semaglutide (brand name Wegovy) in a […]