Weight-loss drugs ‘may lower cancer risk in those with obesity’

GLP-1 drugs, which include Ozempic, are widely prescribed in the US, first for type-2 diabetes and increasingly for weight management. (Reuters pic) ISTANBUL: Drugs like Ozempic and Wegovy, already popular for diabetes and weight loss, may also lower the risk of some cancers especially in women, according to a study by researchers at Indiana University […]

Shared mechanistic pathways of glucagon signalling: Unlocking its potential for treating obesity, metabolic dysfunction‐associated steatotic liver disease, and other cardio‐kidney‐metabolic conditions

Abstract Glucagon is a pancreatic peptide hormone whose receptor (GCGR) is expressed in the liver, kidney, and, to a lesser extent, various other tissues. Glucagon is well known as the counterpart to insulin in glucose homeostasis. However, recent evidence has revealed other potential roles of glucagon, which include the regulation of amino acid metabolism via […]

Danes probe cutting red tape in pharma package talks

Presented by EFPIA By GIEDRĖ PESECKYTĖ with CLAUDIA CHIAPPA, MARI ECCLES and RORY O’NEILL PRESENTED BY View in your browser or listen to audio SNEAK PEEK — The Danish Presidency of the Council of the EU is asking countries for “flexibilities” on the pharma legislation in talks with the European Parliament.   — WHO members […]

Pfizer M&A prospect Metsera heads to phase III with lead GLP-1

Phase IIb data of Metsera Inc.’s lead GLP-1 receptor agonist, MET-097i, showed significant weight loss and good tolerability, supporting a phase III start later this year, and validating Pfizer Inc.’s decision a week ago to buy the obesity-focused company for $7.3 billion.