Novo Nordisk’s 52% Plunge: Is the Company Fumbling Its Leadership in the $150 Billion Weight Loss Market?

Nothing attracts competition like the opportunity for profits, and the weight loss drug market has become arguably the healthcare industry’s hottest opportunity in recent memory. Novo Nordisk (NYSE: NVO) has enjoyed tremendous success with semaglutide, the proprietary drug in Ozempic and Wegovy. However, competition is picking up with multiple next-generation drugs working through clinical testing. […]

Patenting Privation (Part III): Empowering Revenge

Just over a year ago on these pages, I continued our look at the patent franchises protecting the defining drugs of our time, Novo Nordisk and Eli Lilly’s diabetes/weight-loss blockbusters, Ozembic/Wegovy and Mounjaro/Zepbound. As you can imagine with drugs of such culture-defining magnitude, the year that has passed since that column has been full of […]

MCED Test Performance in Obese Individuals

This abstract evaluates a multi-cancer early detection (MCED) blood test specifically designed for individuals with obesity, a group at higher risk for several cancers often without standard screening. The study investigated the test’s ability to accurately detect cancer and identify the tissue of origin using a two-step methylation profiling method. Results showed the test had a high positive predictive value (PPV) and reasonable sensitivity, […]

Glucagon-like peptide 1 level and risk of death within 90 days after intensive care unit admission: A substudy of the IVOIRE cohort

by Marine Jacquier, Annabelle Tavernier, Jean-Pierre Quenot, David Masson, Elea Ksiazek, Isabelle Fournel, Jacques Grober Background Elevated plasma levels of glucagon-like peptide-1 (GLP-1) have been associated with poor clinical outcome in patients with sepsis. This study investigated the association between GLP-1 levels, and survival at 90 days in a large cohort of critically ill patients. […]