AstraZeneca’s New Oral GLP-1 Aids Weight Loss and Lowers Blood Sugar

Closeup of blue pill in palmx

Wednesday, July 8 – AstraZeneca’s new oral GLP-1 pill showed promising results for weight loss and blood sugar in a phase 2 trial. Guido Mieth/Getty Images

A new GLP-1 oral medication from AstraZeneca, known as elecoglipron, lowered blood sugar levels and led to 10.5% weight loss in a phase 2b clinical trial.

Experts say GLP-1 drugs in tablet form may encourage more people to take these medications to help treat type 2 diabetes and obesity.

New weight loss pill beats oral Ozempic in major trial

Wednesday, July 8 – A new once-daily weight-loss pill called orforglipron delivered better weight loss and blood sugar improvements for people with type 2 diabetes than the leading oral semaglutide in a major clinical trial. The tablet could offer a more convenient alternative to injectable drugs like Ozempic and Wegovy because it doesn’t require refrigeration or special timing with meals. It’s also cheaper to manufacture, which could expand access globally.

Generic Mounjaro, Zepbound May Be Coming, Rivaling Current GLP-1s

Tuesday, July 7 – Federal regulators have agreed to review a Swiss pharmaceutical company’s applications for two cheaper generic versions of Zepbound and Mounjaro. MK Photo/Alamy Stock Photo

Federal regulators have agreed to review the applications from Swiss pharmaceutical company Sandoz for two cheaper generic versions of the tirzepatide medications Zepbound and Mounjaro.

Secret Shopper Study Warns About Online GLP-1 Sellers

Tuesday, July 7 – (MedPage Today) — Two-thirds of online GLP-1 receptor agonist sellers did not require speaking with a clinician ahead of a prescription, a secret shopper study revealed.
Out of 49 websites tested, 13 required a video visit and three required…

New CDER appointment elevates longtime GLP-1 reviewer

Tuesday, July 7 – Acting FDA CDER director Michael Davis has promoted a longtime FDA staffer as an acting deputy director at the drug center.

Lisa Yanoff, an agency veteran with expertise in metabolic drug reviews, is taking over …

Oral GLP-1 Drug May Simplify Diabetes Treatment

Tuesday, July 7 – (MedPage Today) — At the American Diabetes Association annual meeting, results from the ACHIEVE-5 trial showed that adding oral orforglipron (Foundayo) to basal insulin significantly improved glycemic control, reduced body weight, and limited…

Wegovy weight-loss pill goes on sale on UK high street and online pharmacies

Tuesday, July 7 – Thousands of people begin receiving their first deliveries of once-a-day medication made by Novo Nordisk A once-a-day Wegovy weight-loss pill has gone on sale at high street and online pharmacies in the UK, but is not yet available on the NHS.Thousands of people began receiving their first deliveries of the pill, made by the Danish drugmaker Novo Nordisk, on Monday. It contains the same active GLP-1 ingredient as the Wegovy jab, semaglutide, and is similarly effective, according to studies. Continue reading…