Breast Cancer - News, Obesity Reviews, Recent Papers, and Clinical Trials
Dehesh T, Fadaghi S, Seyedi M, Abolhadi E, Ilaghi M, Shams P, Ajam F, Mosleh-Shirazi MA, Dehesh P. The relation between obesity and breast cancer risk in women by considering menstruation status and geographical variations: a systematic review and meta-analysis. BMC Womens Health. 2023 Jul 26;23(1):392. doi: 10.1186/s12905-023-02543-5. PMID: 37496015; PMCID: PMC10373406.
Summary
This research paper explores the relationship between obesity and breast cancer risk in women, taking into account both pre- and post-menopausal status as well as geographical variations. Using a meta-analysis of over 100 studies, researchers discovered that obesity appears to have a protective effect against breast cancer in pre-menopausal women, particularly in European women, while in post-menopausal women, obesity increases the risk of developing breast cancer across various continents. The researchers also identified factors that contributed to the heterogeneity observed across the studies, such as study design, geographical location, and hormonal drug use.
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Current 27 Clinical Trials in Obesity and Breast Cancer at 41 sites in the United States (Recruiting or Not Yet Recruting)
| NCT Number | Study Title | Study Status | Conditions | Sponsor |
|---|---|---|---|---|
| NCT06517212 | Tirzepatide in Patients With Obesity or Overweight Who Have High Risk Early Breast Cancer and Are ctDNA+ | NOT_YET_RECRUITING | Breast Cancer|Breast Neoplasms | Baylor Research Institute |
| NCT04720209 | Taking AIM at Breast Cancer | RECRUITING | Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III | Dana-Farber Cancer Institute |
| NCT04913064 | Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer | RECRUITING | Breast Carcinoma | City of Hope Medical Center |
| NCT06318507 | The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy | RECRUITING | Breast Neoplasms | Pennington Biomedical Research Center |
| NCT04003038 | Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery | RECRUITING | Body Mass Index Greater Than or Equal to 30|Malignant Breast Neoplasm|Mammoplasty Patient|Obesity | M.D. Anderson Cancer Center |
| NCT06399276 | 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity | RECRUITING | Breast Cancer | University of Colorado, Denver |
| NCT05193149 | Inspiratory Muscle Training in Obese Breast Cancer Survivors | RECRUITING | Cancer Survivors|Obesity|Breast Cancer | Ohio State University Comprehensive Cancer Center |
| NCT02095184 | GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese Patients | RECRUITING | Breast Cancer | University of Maryland, Baltimore |
| NCT06485089 | Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers | RECRUITING | Obesity|Breast Cancer Risk | University of Kansas Medical Center |
| NCT03824145 | Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer | RECRUITING | Metastatic Breast Cancer | Medical College of Wisconsin |
| NCT06518837 | Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer | NOT_YET_RECRUITING | Hormone Receptor-Positive Breast Cancer|HER2-Negative Breast Cancer | Rutgers, The State University of New Jersey |
| NCT06106477 | Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer | RECRUITING | Breast Cancer | Medical College of Wisconsin |
| NCT03712813 | Effect of Low Intensity Vibration (LIV) on Aromatase Inhibitor- Induced Musculoskeletal Dysfunction in Early Stage Breast Cancer Survivors | RECRUITING | Breast Cancer | Indiana University |
| NCT04365569 | Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program | RECRUITING | Breast Cancer | Case Comprehensive Cancer Center |
| NCT04717050 | Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity | RECRUITING | Breast Cancer|Coronary Artery Disease|Stroke|Type2 Diabetes | Dana-Farber Cancer Institute |
| NCT06195306 | Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction | NOT_YET_RECRUITING | Breast Atypical Hyperplasia|Breast Carcinoma|Breast Ductal Carcinoma In Situ|Breast Lobular Carcinoma In Situ | National Cancer Institute (NCI) |
| NCT05386719 | Cardiometabolic Screening Program | RECRUITING | Breast Cancer|Early-stage Breast Cancer | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
| NCT05780814 | The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer | RECRUITING | Breast Cancer|Insomnia|Weight Gain | Johns Hopkins University |
| NCT05930483 | Remotely Delivered, Culturally Tailored Weight Loss Interventions Among Latina Breast Cancer Survivors | NOT_YET_RECRUITING | Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8 | Fred Hutchinson Cancer Center |
| NCT06504914 | Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors | RECRUITING | Hypertension|Obesity|Nutrition, Healthy | University of Illinois at Chicago |
| NCT05721976 | With Love, Grandma ("Con Cariño, Abuelita") Pilot Study | RECRUITING | Cancer, Breast|Cancer, Uterus|Cancer, Ovary|Obesity|Activity, Motor|Diet, Healthy | University of Miami Sylvester Comprehensive Cancer Center |
| NCT06315296 | An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer | RECRUITING | Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Lung Carcinoma|Metastatic Malignant Neoplasm in the Brain|Stage IV Lung Cancer AJCC v8 | Thomas Jefferson University |
| NCT04965246 | Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors | RECRUITING | Inflammation|Cognitive Impairment|Anxiety|Alcohol Drinking | Milton S. Hershey Medical Center |
| NCT05848856 | The RISC Registry--Risk Informed Screening Registry | NOT_YET_RECRUITING | Breast Cancer Risk|Cardiovascular Disease Risk|Cardiometabolic Risk|Diabetes | Precision Health Equity Initiative |
| NCT06123286 | Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms | NOT_YET_RECRUITING | Breast Cancer|Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)|Joint Pain | Philip Chang |
| NCT06171945 | Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors | RECRUITING | Cancer|Physical Activity|Cancer Survivorship|Mental Health|Obesity | UNC Lineberger Comprehensive Cancer Center |
| NCT01793168 | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | RECRUITING | Rare Disorders|Undiagnosed Disorders|Disorders of Unknown Prevalence|Cornelia De Lange Syndrome|Prenatal Benign Hypophosphatasia|Perinatal Lethal Hypophosphatasia|Odontohypophosphatasia|Adult Hypophosphatasia|Childhood-onset Hypophosphatasia|Infantile Hypophosphatasia|Hypophosphatasia|Kabuki Syndrome|Bohring-Opitz Syndrome|Narcolepsy Without Cataplexy|Narcolepsy-cataplexy|Hypersomnolence Disorder|Idiopathic Hypersomnia Without Long Sleep Time|Idiopathic Hypersomnia With Long Sleep Time|Idiopathic Hypersomnia|Kleine-Levin Syndrome|Kawasaki Disease|Leiomyosarcoma|Leiomyosarcoma of the Corpus Uteri|Leiomyosarcoma of the Cervix Uteri|Leiomyosarcoma of Small Intestine|Acquired Myasthenia Gravis|Addison Disease|Hyperacusis (Hyperacousis)|Juvenile Myasthenia Gravis|Transient Neonatal Myasthenia Gravis|Williams Syndrome|Lyme Disease|Myasthenia Gravis|Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome)|Isolated Klippel-Feil Syndrome|Frasier Syndrome|Denys-Drash Syndrome|Beckwith-Wiedemann Syndrome|Emanuel Syndrome|Isolated Aniridia|Axenfeld-Rieger Syndrome|Aniridia-intellectual Disability Syndrome|Aniridia - Renal Agenesis - Psychomotor Retardation|Aniridia - Ptosis - Intellectual Disability - Familial Obesity|Aniridia - Cerebellar Ataxia - Intellectual Disability|Aniridia - Absent Patella|Aniridia|Peters Anomaly - Cataract|Peters Anomaly|Potocki-Shaffer Syndrome|Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11|Silver-Russell Syndrome Due to Imprinting Defect of 11p15|Silver-Russell Syndrome Due to 11p15 Microduplication|Syndromic Aniridia|WAGR Syndrome|Wolf-Hirschhorn Syndrome|4p16.3 Microduplication Syndrome|4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome|Autosomal Recessive Stickler Syndrome|Stickler Syndrome Type 2|Stickler Syndrome Type 1|Stickler Syndrome|Mucolipidosis Type 4|X-linked Spinocerebellar Ataxia Type 4|X-linked Spinocerebellar Ataxia Type 3|X-linked Intellectual Disability - Ataxia - Apraxia|X-linked Progressive Cerebellar Ataxia|X-linked Non Progressive Cerebellar Ataxia|X-linked Cerebellar Ataxia|Vitamin B12 Deficiency Ataxia|Toxic Exposure Ataxia|Unclassified Autosomal Dominant Spinocerebellar Ataxia|Thyroid Antibody Ataxia|Sporadic Adult-onset Ataxia of Unknown Etiology|Spinocerebellar Ataxia With Oculomotor Anomaly|Spinocerebellar Ataxia With Epilepsy|Spinocerebellar Ataxia With Axonal Neuropathy Type 2|Spinocerebellar Ataxia Type 8|Spinocerebellar Ataxia Type 7|Spinocerebellar Ataxia Type 6|Spinocerebellar Ataxia Type 5|Spinocerebellar Ataxia Type 4|Spinocerebellar Ataxia Type 37|Spinocerebellar Ataxia Type 36|Spinocerebellar Ataxia Type 35|Spinocerebellar Ataxia Type 34|Spinocerebellar Ataxia Type 32|Spinocerebellar Ataxia Type 31|Spinocerebellar Ataxia Type 30|Spinocerebellar Ataxia Type 3|Spinocerebellar Ataxia Type 29|Spinocerebellar Ataxia Type 28|Spinocerebellar Ataxia Type 27|Spinocerebellar Ataxia Type 26|Spinocerebellar Ataxia Type 25|Spinocerebellar Ataxia Type 23|Spinocerebellar Ataxia Type 22|Spinocerebellar Ataxia Type 21|Spinocerebellar Ataxia Type 20|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia Type 19/22|Spinocerebellar Ataxia Type 18|Spinocerebellar Ataxia Type 17|Spinocerebellar Ataxia Type 16|Spinocerebellar Ataxia Type 15/16|Spinocerebellar Ataxia Type 14|Spinocerebellar Ataxia Type 13|Spinocerebellar Ataxia Type 12|Spinocerebellar Ataxia Type 11|Spinocerebellar Ataxia Type 10|Spinocerebellar Ataxia Type 1 With Axonal Neuropathy|Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia - Unknown|Spinocerebellar Ataxia - Dysmorphism|Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature|Spasticity-ataxia-gait Anomalies Syndrome|Spastic Ataxia With Congenital Miosis|Spastic Ataxia - Corneal Dystrophy|Spastic Ataxia|Rare Hereditary Ataxia|Rare Ataxia|Recessive Mitochondrial Ataxia Syndrome|Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature|Posterior Column Ataxia - Retinitis Pigmentosa|Post-Stroke Ataxia|Post-Head Injury Ataxia|Post Vaccination Ataxia|Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract|Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus|Non-hereditary Degenerative Ataxia|Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity|Olivopontocerebellar Atrophy - Deafness|NARP Syndrome|Myoclonus - Cerebellar Ataxia - Deafness|Multiple System Atrophy, Parkinsonian Type|Multiple System Atrophy, Cerebellar Type|Multiple System Atrophy|Maternally-inherited Leigh Syndrome|Machado-Joseph Disease Type 3|Machado-Joseph Disease Type 2|Machado-Joseph Disease Type 1|Leigh Syndrome|Late-onset Ataxia With Dementia|Infection or Post Infection Ataxia|GAD Ataxia|Hereditary Episodic Ataxia|Gliadin/Gluten Ataxia|Friedreich Ataxia|Fragile X-associated Tremor/Ataxia Syndrome|Familial Paroxysmal Ataxia|Exposure to Medications Ataxia|Episodic Ataxia With Slurred Speech|Episodic Ataxia Unknown Type|Episodic Ataxia Type 7|Episodic Ataxia Type 6|Episodic Ataxia Type 5|Episodic Ataxia Type 4|Episodic Ataxia Type 3|Episodic Ataxia Type 1|Epilepsy and/or Ataxia With Myoclonus as Major Feature|Early-onset Spastic Ataxia-neuropathy Syndrome|Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity|Early-onset Cerebellar Ataxia With Retained Tendon Reflexes|Early-onset Ataxia With Dementia|Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia|Dilated Cardiomyopathy With Ataxia|Cataract - Ataxia - Deafness|Cerebellar Ataxia, Cayman Type|Cerebellar Ataxia With Peripheral Neuropathy|Cerebellar Ataxia - Hypogonadism|Cerebellar Ataxia - Ectodermal Dysplasia|Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss|Brain Tumor Ataxia|Brachydactyly - Nystagmus - Cerebellar Ataxia|Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia|Autosomal Recessive Syndromic Cerebellar Ataxia|Autosomal Recessive Spastic Ataxia With Leukoencephalopathy|Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay|Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria|Autosomal Recessive Spastic Ataxia|Autosomal Recessive Metabolic Cerebellar Ataxia|Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine|Autosomal Recessive Ataxia, Beauce Type|Autosomal Recessive Ataxia Due to Ubiquinone Deficiency|Autosomal Recessive Ataxia Due to PEX10 Deficiency|Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia|Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency|Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency|Autosomal Recessive Congenital Cerebellar Ataxia|Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome|Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity|Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency|Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect|Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion|Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation|Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness|Autosomal Recessive Cerebellar Ataxia|Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly|Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation|Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy|Autosomal Dominant Spastic Ataxia Type 1|Autosomal Dominant Spastic Ataxia|Autosomal Dominant Optic Atrophy|Ataxia-telangiectasia Variant|Ataxia-telangiectasia|Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy|Autosomal Dominant Cerebellar Ataxia Type 4|Autosomal Dominant Cerebellar Ataxia Type 3|Autosomal Dominant Cerebellar Ataxia Type 2|Autosomal Dominant Cerebellar Ataxia Type 1|Autosomal Dominant Cerebellar Ataxia|Ataxia-telangiectasia-like Disorder|Ataxia With Vitamin E Deficiency|Ataxia With Dementia|Ataxia - Oculomotor Apraxia Type 1|Ataxia - Other|Ataxia - Genetic Diagnosis - Unknown|Acquired Ataxia|Adult-onset Autosomal Recessive Cerebellar Ataxia|Alcohol Related Ataxia|Multiple Endocrine Neoplasia|Multiple Endocrine Neoplasia Type II|Multiple Endocrine Neoplasia Type 1|Multiple Endocrine Neoplasia Type 2|Multiple Endocrine Neoplasia, Type IV|Multiple Endocrine Neoplasia, Type 3|Multiple Endocrine Neoplasia (MEN) Syndrome|Multiple Endocrine Neoplasia Type 2B|Multiple Endocrine Neoplasia Type 2A|Atypical Hemolytic Uremic Syndrome|Atypical HUS|Wiedemann-Steiner Syndrome|Breast Implant-Associated Anaplastic Large Cell Lymphoma|Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)|Hemophagocytic Lymphohistiocytosis|Behcet's Disease|Alagille Syndrome|Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD)|Lowe Syndrome|Pitt Hopkins Syndrome|1p36 Deletion Syndrome|Jansen Type Metaphyseal Chondrodysplasia|Cockayne Syndrome|Chronic Recurrent Multifocal Osteomyelitis|CRMO|Malan Syndrome|Hereditary Sensory and Autonomic Neuropathy Type Ie|VCP Disease|Hypnic Jerking|Sleep Myoclonus|Mollaret Meningitis|Recurrent Viral Meningitis|CRB1|Leber Congenital Amaurosis|Retinitis Pigmentosa|Rare Retinal Disorder|KCNMA1-Channelopathy|Primary Biliary Cirrhosis|ZMYND11|Transient Global Amnesia|Glycogen Storage Disease|Alstrom Syndrome|White Sutton Syndrome|DNM1|EIEE31|Myhre Syndrome|Recurrent Respiratory Papillomatosis|Laryngeal Papillomatosis|Tracheal Papillomatosis|Refsum Disease|Nicolaides Baraitser Syndrome|Leukodystrophy|Tango2|Cauda Equina Syndrome|Rare Gastrointestinal Disorders|Achalasia-Addisonian Syndrome|Achalasia Cardia|Achalasia Icrocephaly Syndrome|Anal Fistula|Congenital Sucrase-Isomaltase Deficiency|Eosinophilic Gastroenteritis|Idiopathic Gastroparesis|Hirschsprung Disease|Rare Inflammatory Bowel Disease|Intestinal Pseudo-Obstruction|Scleroderma|Short Bowel Syndrome|Sacral Agenesis|Sacral Agenesis Syndrome|Caudal Regression|Scheuermann Disease|SMC1A Truncated Mutations (Causing Loss of Gene Function)|Cystinosis|Juvenile Nephropathic Cystinosis|Nephropathic Cystinosis|Kennedy Disease|Spinal Bulbar Muscular Atrophy|Warburg Micro Syndrome|Mucolipidoses|Mitochondrial Diseases|Mitochondrial Aminoacyl-tRNA Synthetases|Mt-aaRS Disorders|Hypertrophic Olivary Degeneration|Non-Ketotic Hyperglycinemia|Fish Odor Syndrome|Halitosis|Isolated Congenital Asplenia|Lambert Eaton (LEMS)|Biliary Atresia|STAG1 Gene Mutation|Coffin Lowry Syndrome|Borjeson-Forssman-Lehman Syndrome|Blau Syndrome|Arginase 1 Deficiency|HSPB8 Myopathy|Beta-Mannosidosis|TBX4 Syndrome|DHDDS Gene Mutations|MAND-MBD5-Associated Neurodevelopmental Disorder|Constitutional Mismatch Repair Deficiency (CMMRD)|SPATA5 Disorder|SPATA5L1 Related Disorder | Sanford Health |
Clinical Trials
Breast Cancer Clinical Trials in the United States that involve obesity – Total of 130 (October 7, 2024)
| NCT Number | Study Title | Study URL | Acronym | Study Status | Conditions |
|---|---|---|---|---|---|
| NCT01302379 | Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01302379 | COMPLETED | Breast Neoplasms | |
| NCT00933309 | The Impact of Obesity and Obesity Treatments on Breast Cancer | https://clinicaltrials.gov/study/NCT00933309 | COMPLETED | Breast Cancer | |
| NCT06517212 | Tirzepatide in Patients With Obesity or Overweight Who Have High Risk Early Breast Cancer and Are ctDNA+ | https://clinicaltrials.gov/study/NCT06517212 | NOT_YET_RECRUITING | Breast Cancer|Breast Neoplasms | |
| NCT04720209 | Taking AIM at Breast Cancer | https://clinicaltrials.gov/study/NCT04720209 | RECRUITING | Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III | |
| NCT04913064 | Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer | https://clinicaltrials.gov/study/NCT04913064 | RECRUITING | Breast Carcinoma | |
| NCT02750826 | Breast Cancer WEight Loss Study (BWEL Study) | https://clinicaltrials.gov/study/NCT02750826 | ACTIVE_NOT_RECRUITING | Breast Carcinoma | |
| NCT03091842 | Exercise Intervention in Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer | https://clinicaltrials.gov/study/NCT03091842 | WITHDRAWN | Cancer Survivor|Central Obesity|Estrogen Receptor Positive|Postmenopausal|Progesterone Receptor Positive|Stage I Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer | |
| NCT04003038 | Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery | https://clinicaltrials.gov/study/NCT04003038 | RECRUITING | Body Mass Index Greater Than or Equal to 30|Malignant Breast Neoplasm|Mammoplasty Patient|Obesity | |
| NCT06399276 | 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity | https://clinicaltrials.gov/study/NCT06399276 | RECRUITING | Breast Cancer | |
| NCT02681120 | Pilot Study of the Effect of Weight Loss on Breast Tissue and Blood Biomarkers in Women at Increased Risk for Breast Cancer | https://clinicaltrials.gov/study/NCT02681120 | COMPLETED | Breast Neoplasms|Obesity | |
| NCT03111680 | Healthy Families to Change Obesity in Public Housing Residents | https://clinicaltrials.gov/study/NCT03111680 | COMPLETED | Breast Cancer | |
| NCT02028221 | Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk | https://clinicaltrials.gov/study/NCT02028221 | COMPLETED | Breast Cancer Prevention | |
| NCT01472445 | Vitamin D and Breast Cancer: Does Weight Make a Difference? | https://clinicaltrials.gov/study/NCT01472445 | TERMINATED | Breast Cancer | |
| NCT02538484 | Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Subjects | https://clinicaltrials.gov/study/NCT02538484 | COMPLETED | Breast Cancer | |
| NCT04504201 | Patient-centered Communication About Healthy Weight in Early Breast Cancer | https://clinicaltrials.gov/study/NCT04504201 | COMPLETED | Breast Cancer | |
| NCT01975363 | Pilot Study of Curcumin for Women With Obesity and High Risk for Breast Cancer | https://clinicaltrials.gov/study/NCT01975363 | COMPLETED | Atypical Ductal Breast Hyperplasia|BRCA1 Gene Mutation|BRCA2 Gene Mutation|Ductal Breast Carcinoma in Situ|Lobular Breast Carcinoma in Situ | |
| NCT03575624 | Changing Health Behaviors to Manage Chronic Conditions in Community-dwelling African American Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT03575624 | COMPLETED | Breast Cancer Female|Survivorship | |
| NCT01127867 | A Pilot Study of Docosahexaenoic Acid (DHA) in Obese Menopausal Women | https://clinicaltrials.gov/study/NCT01127867 | COMPLETED | Breast Cancer|Obesity | |
| NCT02095184 | GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese Patients | https://clinicaltrials.gov/study/NCT02095184 | RECRUITING | Breast Cancer | |
| NCT02062255 | Impact of COX2 on Sera Biomarkers From Obese Subjects | https://clinicaltrials.gov/study/NCT02062255 | COMPLETED | Breast Cancer Survivors | |
| NCT00859989 | A Weight-Loss Program in Helping Obese Black Women Lose Weight | https://clinicaltrials.gov/study/NCT00859989 | UNKNOWN | Breast Cancer|Obesity|Weight Changes | |
| NCT04117438 | Tell us Your Food Story | https://clinicaltrials.gov/study/NCT04117438 | WITHDRAWN | Breast Neoplasms | |
| NCT01542203 | Impact of Body Weight on Pharmacokinetic Analysis of Doxorubicin + Cyclophosphamide in Breast Cancer | https://clinicaltrials.gov/study/NCT01542203 | WITHDRAWN | Breast Cancer | |
| NCT05113485 | UCLA Breast Cancer Survivor Health Promotion Research Study | https://clinicaltrials.gov/study/NCT05113485 | UNKNOWN | Breast Cancer | |
| NCT02432950 | Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer | https://clinicaltrials.gov/study/NCT02432950 | COMPLETED | Obesity|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer | |
| NCT01582685 | Exercise in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01582685 | WITHDRAWN | Breast Cancer|Obesity | |
| NCT06485089 | Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers | https://clinicaltrials.gov/study/NCT06485089 | NOT_YET_RECRUITING | Obesity|Breast Cancer Risk | |
| NCT01784042 | Dietary Energy Restriction and Omega-3 Fatty Acids on Mammary Tissue | https://clinicaltrials.gov/study/NCT01784042 | WITHDRAWN | Breast Cancer | |
| NCT03029182 | Simulated-altitude to Optimize Aerobic Exercise Among Breast Cancer Survivors With Limited Mobility | https://clinicaltrials.gov/study/NCT03029182 | COMPLETED | Obesity|Breast Cancer | |
| NCT01793948 | Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer | https://clinicaltrials.gov/study/NCT01793948 | COMPLETED | Breast Cancer|Obesity | |
| NCT01837147 | Using Technology to Improve Physical Activity Levels Among Postmenopausal Women (The Active & Aware Study) | https://clinicaltrials.gov/study/NCT01837147 | COMPLETED | Breast Cancer | |
| NCT01441011 | Rural Women Connecting for Better Health | https://clinicaltrials.gov/study/NCT01441011 | COMPLETED | Breast Cancer|Obesity | |
| NCT04291950 | Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women | https://clinicaltrials.gov/study/NCT04291950 | WITHDRAWN | Triple Negative Breast Cancer | |
| NCT04298086 | A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer | https://clinicaltrials.gov/study/NCT04298086 | ACTIVE_NOT_RECRUITING | Breast Cancer|Primary Hormone Receptor Positive Breast Cancer | |
| NCT01504789 | Part II: Exercise in Hispanic Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01504789 | ACTIVE_NOT_RECRUITING | Breast Cancer | |
| NCT00343434 | Soy-Based Meal Replacement in Helping Women With Stage I, Stage II, or Stage III Breast Cancer in Complete Remission Lose Weight | https://clinicaltrials.gov/study/NCT00343434 | COMPLETED | Breast Cancer|Obesity | |
| NCT01537029 | Effect of Weight on the Population Pharmacokinetic Analysis of Doxorubicin and Cyclophosphamide | https://clinicaltrials.gov/study/NCT01537029 | COMPLETED | Breast Cancer|Obesity | |
| NCT00131950 | Effect of Lifestyle Factors and Hormone Function on Breast Density in Healthy Hispanic Women Who Are Undergoing Mammography for Breast Cancer Screening | https://clinicaltrials.gov/study/NCT00131950 | COMPLETED | Breast Cancer | |
| NCT00120029 | Peer Counseling for Weight Loss | https://clinicaltrials.gov/study/NCT00120029 | UNKNOWN | Breast Cancer | |
| NCT01166672 | BCRL Prevention Pilot | https://clinicaltrials.gov/study/NCT01166672 | COMPLETED | Obesity|Breast Cancer | |
| NCT01627067 | Exemestane-RAD001-Metformin | https://clinicaltrials.gov/study/NCT01627067 | TERMINATED | Breast Cancer | |
| NCT02574507 | Behavioral Weight and Symptom Management for Breast Cancer Survivors and Partners | https://clinicaltrials.gov/study/NCT02574507 | COMPLETED | Breast Cancer | |
| NCT06106477 | Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer | https://clinicaltrials.gov/study/NCT06106477 | RECRUITING | Breast Cancer | |
| NCT03712813 | Effect of Low Intensity Vibration (LIV) on Aromatase Inhibitor- Induced Musculoskeletal Dysfunction in Early Stage Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT03712813 | RECRUITING | Breast Cancer | |
| NCT05265715 | A Low AGE (Advanced Glycation End-product) Dietary Intervention for Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT05265715 | COMPLETED | Breast Cancer | |
| NCT02969291 | A Home-Based Study to Enhance Activity in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT02969291 | COMPLETED | Breast Cancer | |
| NCT02279303 | Rx for Better Breast Health | https://clinicaltrials.gov/study/NCT02279303 | COMPLETED | Breast Cancer | |
| NCT04129346 | Technology-Supported Physical Activity Intervention for Metastatic Breast Cancer Survivors: Fit2ThriveMB | https://clinicaltrials.gov/study/NCT04129346 | COMPLETED | Metastatic Breast Cancer|Obesity | |
| NCT04365569 | Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program | https://clinicaltrials.gov/study/NCT04365569 | RECRUITING | Breast Cancer | |
| NCT04170335 | Effects of Bariatric Surgery on Breast Density Improvement and Impact on Breast Cancer Risk in Severe Obese Patients | https://clinicaltrials.gov/study/NCT04170335 | WITHDRAWN | Breast Cancer|Morbid Obesity|Bariatric Surgery Candidate | |
| NCT03270111 | High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women | https://clinicaltrials.gov/study/NCT03270111 | COMPLETED | Breast Cancer Female | |
| NCT02940470 | Weight Loss Pilot Study in Postmenopausal Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT02940470 | COMPLETED | Breast Cancer|Obesity|Overweight | |
| NCT04717050 | Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity | https://clinicaltrials.gov/study/NCT04717050 | RECRUITING | Breast Cancer|Coronary Artery Disease|Stroke|Type2 Diabetes | |
| NCT00904033 | Calcitriol, Physical Activity, and Bone Health in Cancer Survivors | https://clinicaltrials.gov/study/NCT00904033 | COMPLETED | Breast Neoplasms|Bone and Bones | |
| NCT04330339 | Prolonged Nightly Fasting in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04330339 | COMPLETED | Fasting|Breast Cancer|Survivorship|Breast Cancer Recurrent | |
| NCT00470119 | Effect of a Low-Calorie Diet and/or Exercise Program on Risk Factors for Developing Breast Cancer in Overweight or Obese Postmenopausal Women | https://clinicaltrials.gov/study/NCT00470119 | COMPLETED | Breast Cancer|Obesity|Weight Changes | |
| NCT06195306 | Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction | https://clinicaltrials.gov/study/NCT06195306 | NOT_YET_RECRUITING | Breast Atypical Hyperplasia|Breast Carcinoma|Breast Ductal Carcinoma In Situ|Breast Lobular Carcinoma In Situ | |
| NCT05386719 | Cardiometabolic Screening Program | https://clinicaltrials.gov/study/NCT05386719 | RECRUITING | Breast Cancer|Early-stage Breast Cancer | |
| NCT04321135 | Avanzando Juntas: Adapting an Evidence Based Weight Loss Program for Hispanic Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04321135 | COMPLETED | Breast Cancer|Gynecologic Cancer | |
| NCT04967209 | Investigation of a Digital Healthy Habits Program for Individuals With Breast Cancer | https://clinicaltrials.gov/study/NCT04967209 | COMPLETED | Cancer|Breast Cancer|Obesity|Overweight and Obesity|Overweight | |
| NCT04554316 | Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery | https://clinicaltrials.gov/study/NCT04554316 | COMPLETED | Scar|Breast Neoplasms|Breast Diseases|Surgical Wound | |
| NCT00872677 | Weight Loss Counseling for African American Women Who Are Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT00872677 | COMPLETED | Breast Cancer|Obesity|Weight Changes | |
| NCT02938780 | Using Behavioral Economics to Achieve Improved Healthy Behavior Outcomes in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT02938780 | COMPLETED | Breast Cancer Female | |
| NCT02677857 | Developing a Healthy Lifestyle in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT02677857 | TERMINATED | Breast Cancer|Sedentary Lifestyle | |
| NCT03120390 | Physical Activity in Reducing Metabolic Dysregulation (MetD) in Obese Latina Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT03120390 | WITHDRAWN | Cancer Survivor|Central Obesity|No Evidence of Disease | |
| NCT04741802 | TOPS for African American Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04741802 | COMPLETED | Feasibility and Acceptability of the TOPS Program|Obesity|Breast Cancer|Weight Loss | |
| NCT04210128 | Glucose Monitoring to Predict and Treat High Glucose Levels After Steroid Treatment | https://clinicaltrials.gov/study/NCT04210128 | COMPLETED | Breast Cancer|Pancreatic Cancer|Diabetes|Pre Diabetes | |
| NCT02871388 | Addressing Modifiable Breast Cancer Risk Factors With Project CONECT | https://clinicaltrials.gov/study/NCT02871388 | COMPLETED | Weight Loss|Breast Cancer Risk Factors | |
| NCT01157130 | Breast Cancer Patients: A Breast Cancer Rehabilitation and Exercise Laboratory | https://clinicaltrials.gov/study/NCT01157130 | UNKNOWN | Early Stage Breast Cancer (Stage 0-III) | |
| NCT02370277 | Effects of Chemotherapy on Intestinal Bacteria in Patients With Newly Diagnosed Breast Cancer | https://clinicaltrials.gov/study/NCT02370277 | COMPLETED | Ductal Breast Carcinoma In Situ|Invasive Breast Carcinoma|Stage I Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer | |
| NCT04454086 | Exercise and Diet Counseling Program in Improving Quality of Life in Stage I-III Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04454086 | COMPLETED | Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Cancer Survivor|Obesity|Overweight|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8 | |
| NCT01871116 | POWER-remote Weight Loss Program in Early Stage Breast Cancer | https://clinicaltrials.gov/study/NCT01871116 | COMPLETED | Early Stage Breast Cancer | |
| NCT05930483 | Remotely Delivered, Culturally Tailored Weight Loss Interventions Among Latina Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT05930483 | NOT_YET_RECRUITING | Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8 | |
| NCT02037542 | A Study of Lifestyle Intervention in Overweight or Obese Women With Early Stage Breast Cancer | https://clinicaltrials.gov/study/NCT02037542 | COMPLETED | Weight | |
| NCT03546972 | Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants | https://clinicaltrials.gov/study/NCT03546972 | ACTIVE_NOT_RECRUITING | Deleterious BRCA1 Gene Mutation|Deleterious BRCA2 Gene Mutation|Ductal Breast Carcinoma In Situ|Obesity|Overweight|Premalignant Lesion | |
| NCT02923401 | High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer | https://clinicaltrials.gov/study/NCT02923401 | COMPLETED | Disorders of Breast | |
| NCT00509626 | Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy | https://clinicaltrials.gov/study/NCT00509626 | COMPLETED | Breast Cancer|Depression|Fatigue|Psychosocial Effects of Cancer and Its Treatment|Weight Changes | |
| NCT05012176 | An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT05012176 | ACTIVE_NOT_RECRUITING | Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Breast Ductal Carcinoma In Situ|Invasive Breast Carcinoma|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8 | |
| NCT04799665 | Dedicated Breast CT for Quantitative Breast Density Measurements in Mexican-origin Women in Southern Arizona | https://clinicaltrials.gov/study/NCT04799665 | COMPLETED | Metabolic Syndrome|Obesity Associated Disorder | |
| NCT02103140 | An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer | https://clinicaltrials.gov/study/NCT02103140 | ACTIVE_NOT_RECRUITING | Metabolic Syndrome|Obesity | |
| NCT04753268 | Mobile Behavior Change Program for Weight Loss in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04753268 | COMPLETED | Weight Loss|Behavior, Health | |
| NCT03284346 | Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors | https://clinicaltrials.gov/study/NCT03284346 | TERMINATED | Cancer Survivor|No Evidence of Disease|Obesity|Overweight|Prostate Carcinoma|Sedentary Lifestyle|Stage I Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer | |
| NCT05721976 | With Love, Grandma ("Con Cariño, Abuelita") Pilot Study | https://clinicaltrials.gov/study/NCT05721976 | RECRUITING | Cancer, Breast|Cancer, Uterus|Cancer, Ovary|Obesity|Activity, Motor|Diet, Healthy | |
| NCT06315296 | An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer | https://clinicaltrials.gov/study/NCT06315296 | RECRUITING | Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Lung Carcinoma|Metastatic Malignant Neoplasm in the Brain|Stage IV Lung Cancer AJCC v8 | |
| NCT04352530 | Culturally Appropriate Nutrition Communication for Mexican American Women | https://clinicaltrials.gov/study/NCT04352530 | COMPLETED | Lifestyle Risk Reduction|Nutrition Poor|Chronic Disease|Obesity|Cancer, Breast | |
| NCT03751449 | Exercise and Nutrition Education in Improving Physical Function and Quality of Life in Older Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT03751449 | TERMINATED | Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Cancer Survivor|Inactivity|Obesity|Overweight|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8 | |
| NCT06123286 | Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms | https://clinicaltrials.gov/study/NCT06123286 | NOT_YET_RECRUITING | Breast Cancer|Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)|Joint Pain | |
| NCT00032201 | Cell Lines From High-Risk Breast Tissue | https://clinicaltrials.gov/study/NCT00032201 | COMPLETED | Healthy | |
| NCT04063410 | Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy | https://clinicaltrials.gov/study/NCT04063410 | WITHDRAWN | Mammoplasty Patient | |
| NCT04499950 | Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study | https://clinicaltrials.gov/study/NCT04499950 | A-NEW | ACTIVE_NOT_RECRUITING | Breast Cancer|Overweight or Obesity |
| NCT03779867 | Acute Exercise Intervention in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT03779867 | ACE | ACTIVE_NOT_RECRUITING | Breast Carcinoma |
| NCT04534309 | Behavioral Weight Loss Program for Cancer Survivors in Maryland | https://clinicaltrials.gov/study/NCT04534309 | ASPIRE | COMPLETED | Breast Cancer|Prostate Cancer|Melanoma (Skin)|Endometrial Cancer|Gallbladder Cancer|Rectal Cancer|Kidney Cancer|Bladder Cancer |
| NCT06171945 | Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors | https://clinicaltrials.gov/study/NCT06171945 | AYAConnect | RECRUITING | Cancer|Physical Activity|Cancer Survivorship|Mental Health|Obesity |
| NCT04576247 | Combined Modality Exercise and Appetite in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04576247 | CARE | TERMINATED | Breast Cancer Female|Overweight and Obesity |
| NCT01315483 | Diet Composition, Weight Control, and Breast Carcinogenesis | https://clinicaltrials.gov/study/NCT01315483 | CHOICE | COMPLETED | Breast Cancer |
| NCT03542604 | Cancer, Obesity/Overweight and Insomnia Study | https://clinicaltrials.gov/study/NCT03542604 | COIN | COMPLETED | Breast Cancer|Overweight and Obesity|Insomnia |
| NCT05780814 | The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer | https://clinicaltrials.gov/study/NCT05780814 | COIN | RECRUITING | Breast Cancer|Insomnia|Weight Gain |
| NCT01793168 | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | https://clinicaltrials.gov/study/NCT01793168 | CoRDS | RECRUITING | Rare Disorders|Undiagnosed Disorders|Disorders of Unknown Prevalence|Cornelia De Lange Syndrome|Prenatal Benign Hypophosphatasia|Perinatal Lethal Hypophosphatasia|Odontohypophosphatasia|Adult Hypophosphatasia|Childhood-onset Hypophosphatasia|Infantile Hypophosphatasia|Hypophosphatasia|Kabuki Syndrome|Bohring-Opitz Syndrome|Narcolepsy Without Cataplexy|Narcolepsy-cataplexy|Hypersomnolence Disorder|Idiopathic Hypersomnia Without Long Sleep Time|Idiopathic Hypersomnia With Long Sleep Time|Idiopathic Hypersomnia|Kleine-Levin Syndrome|Kawasaki Disease|Leiomyosarcoma|Leiomyosarcoma of the Corpus Uteri|Leiomyosarcoma of the Cervix Uteri|Leiomyosarcoma of Small Intestine|Acquired Myasthenia Gravis|Addison Disease|Hyperacusis (Hyperacousis)|Juvenile Myasthenia Gravis|Transient Neonatal Myasthenia Gravis|Williams Syndrome|Lyme Disease|Myasthenia Gravis|Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome)|Isolated Klippel-Feil Syndrome|Frasier Syndrome|Denys-Drash Syndrome|Beckwith-Wiedemann Syndrome|Emanuel Syndrome|Isolated Aniridia|Axenfeld-Rieger Syndrome|Aniridia-intellectual Disability Syndrome|Aniridia - Renal Agenesis - Psychomotor Retardation|Aniridia - Ptosis - Intellectual Disability - Familial Obesity|Aniridia - Cerebellar Ataxia - Intellectual Disability|Aniridia - Absent Patella|Aniridia|Peters Anomaly - Cataract|Peters Anomaly|Potocki-Shaffer Syndrome|Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11|Silver-Russell Syndrome Due to Imprinting Defect of 11p15|Silver-Russell Syndrome Due to 11p15 Microduplication|Syndromic Aniridia|WAGR Syndrome|Wolf-Hirschhorn Syndrome|4p16.3 Microduplication Syndrome|4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome|Autosomal Recessive Stickler Syndrome|Stickler Syndrome Type 2|Stickler Syndrome Type 1|Stickler Syndrome|Mucolipidosis Type 4|X-linked Spinocerebellar Ataxia Type 4|X-linked Spinocerebellar Ataxia Type 3|X-linked Intellectual Disability - Ataxia - Apraxia|X-linked Progressive Cerebellar Ataxia|X-linked Non Progressive Cerebellar Ataxia|X-linked Cerebellar Ataxia|Vitamin B12 Deficiency Ataxia|Toxic Exposure Ataxia|Unclassified Autosomal Dominant Spinocerebellar Ataxia|Thyroid Antibody Ataxia|Sporadic Adult-onset Ataxia of Unknown Etiology|Spinocerebellar Ataxia With Oculomotor Anomaly|Spinocerebellar Ataxia With Epilepsy|Spinocerebellar Ataxia With Axonal Neuropathy Type 2|Spinocerebellar Ataxia Type 8|Spinocerebellar Ataxia Type 7|Spinocerebellar Ataxia Type 6|Spinocerebellar Ataxia Type 5|Spinocerebellar Ataxia Type 4|Spinocerebellar Ataxia Type 37|Spinocerebellar Ataxia Type 36|Spinocerebellar Ataxia Type 35|Spinocerebellar Ataxia Type 34|Spinocerebellar Ataxia Type 32|Spinocerebellar Ataxia Type 31|Spinocerebellar Ataxia Type 30|Spinocerebellar Ataxia Type 3|Spinocerebellar Ataxia Type 29|Spinocerebellar Ataxia Type 28|Spinocerebellar Ataxia Type 27|Spinocerebellar Ataxia Type 26|Spinocerebellar Ataxia Type 25|Spinocerebellar Ataxia Type 23|Spinocerebellar Ataxia Type 22|Spinocerebellar Ataxia Type 21|Spinocerebellar Ataxia Type 20|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia Type 19/22|Spinocerebellar Ataxia Type 18|Spinocerebellar Ataxia Type 17|Spinocerebellar Ataxia Type 16|Spinocerebellar Ataxia Type 15/16|Spinocerebellar Ataxia Type 14|Spinocerebellar Ataxia Type 13|Spinocerebellar Ataxia Type 12|Spinocerebellar Ataxia Type 11|Spinocerebellar Ataxia Type 10|Spinocerebellar Ataxia Type 1 With Axonal Neuropathy|Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia - Unknown|Spinocerebellar Ataxia - Dysmorphism|Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature|Spasticity-ataxia-gait Anomalies Syndrome|Spastic Ataxia With Congenital Miosis|Spastic Ataxia - Corneal Dystrophy|Spastic Ataxia|Rare Hereditary Ataxia|Rare Ataxia|Recessive Mitochondrial Ataxia Syndrome|Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature|Posterior Column Ataxia - Retinitis Pigmentosa|Post-Stroke Ataxia|Post-Head Injury Ataxia|Post Vaccination Ataxia|Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract|Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus|Non-hereditary Degenerative Ataxia|Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity|Olivopontocerebellar Atrophy - Deafness|NARP Syndrome|Myoclonus - Cerebellar Ataxia - Deafness|Multiple System Atrophy, Parkinsonian Type|Multiple System Atrophy, Cerebellar Type|Multiple System Atrophy|Maternally-inherited Leigh Syndrome|Machado-Joseph Disease Type 3|Machado-Joseph Disease Type 2|Machado-Joseph Disease Type 1|Leigh Syndrome|Late-onset Ataxia With Dementia|Infection or Post Infection Ataxia|GAD Ataxia|Hereditary Episodic Ataxia|Gliadin/Gluten Ataxia|Friedreich Ataxia|Fragile X-associated Tremor/Ataxia Syndrome|Familial Paroxysmal Ataxia|Exposure to Medications Ataxia|Episodic Ataxia With Slurred Speech|Episodic Ataxia Unknown Type|Episodic Ataxia Type 7|Episodic Ataxia Type 6|Episodic Ataxia Type 5|Episodic Ataxia Type 4|Episodic Ataxia Type 3|Episodic Ataxia Type 1|Epilepsy and/or Ataxia With Myoclonus as Major Feature|Early-onset Spastic Ataxia-neuropathy Syndrome|Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity|Early-onset Cerebellar Ataxia With Retained Tendon Reflexes|Early-onset Ataxia With Dementia|Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia|Dilated Cardiomyopathy With Ataxia|Cataract - Ataxia - Deafness|Cerebellar Ataxia, Cayman Type|Cerebellar Ataxia With Peripheral Neuropathy|Cerebellar Ataxia - Hypogonadism|Cerebellar Ataxia - Ectodermal Dysplasia|Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss|Brain Tumor Ataxia|Brachydactyly - Nystagmus - Cerebellar Ataxia|Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia|Autosomal Recessive Syndromic Cerebellar Ataxia|Autosomal Recessive Spastic Ataxia With Leukoencephalopathy|Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay|Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria|Autosomal Recessive Spastic Ataxia|Autosomal Recessive Metabolic Cerebellar Ataxia|Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine|Autosomal Recessive Ataxia, Beauce Type|Autosomal Recessive Ataxia Due to Ubiquinone Deficiency|Autosomal Recessive Ataxia Due to PEX10 Deficiency|Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia|Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency|Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency|Autosomal Recessive Congenital Cerebellar Ataxia|Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome|Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity|Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency|Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect|Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion|Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation|Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness|Autosomal Recessive Cerebellar Ataxia|Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly|Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation|Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy|Autosomal Dominant Spastic Ataxia Type 1|Autosomal Dominant Spastic Ataxia|Autosomal Dominant Optic Atrophy|Ataxia-telangiectasia Variant|Ataxia-telangiectasia|Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy|Autosomal Dominant Cerebellar Ataxia Type 4|Autosomal Dominant Cerebellar Ataxia Type 3|Autosomal Dominant Cerebellar Ataxia Type 2|Autosomal Dominant Cerebellar Ataxia Type 1|Autosomal Dominant Cerebellar Ataxia|Ataxia-telangiectasia-like Disorder|Ataxia With Vitamin E Deficiency|Ataxia With Dementia|Ataxia - Oculomotor Apraxia Type 1|Ataxia - Other|Ataxia - Genetic Diagnosis - Unknown|Acquired Ataxia|Adult-onset Autosomal Recessive Cerebellar Ataxia|Alcohol Related Ataxia|Multiple Endocrine Neoplasia|Multiple Endocrine Neoplasia Type II|Multiple Endocrine Neoplasia Type 1|Multiple Endocrine Neoplasia Type 2|Multiple Endocrine Neoplasia, Type IV|Multiple Endocrine Neoplasia, Type 3|Multiple Endocrine Neoplasia (MEN) Syndrome|Multiple Endocrine Neoplasia Type 2B|Multiple Endocrine Neoplasia Type 2A|Atypical Hemolytic Uremic Syndrome|Atypical HUS|Wiedemann-Steiner Syndrome|Breast Implant-Associated Anaplastic Large Cell Lymphoma|Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)|Hemophagocytic Lymphohistiocytosis|Behcet's Disease|Alagille Syndrome|Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD)|Lowe Syndrome|Pitt Hopkins Syndrome|1p36 Deletion Syndrome|Jansen Type Metaphyseal Chondrodysplasia|Cockayne Syndrome|Chronic Recurrent Multifocal Osteomyelitis|CRMO|Malan Syndrome|Hereditary Sensory and Autonomic Neuropathy Type Ie|VCP Disease|Hypnic Jerking|Sleep Myoclonus|Mollaret Meningitis|Recurrent Viral Meningitis|CRB1|Leber Congenital Amaurosis|Retinitis Pigmentosa|Rare Retinal Disorder|KCNMA1-Channelopathy|Primary Biliary Cirrhosis|ZMYND11|Transient Global Amnesia|Glycogen Storage Disease|Alstrom Syndrome|White Sutton Syndrome|DNM1|EIEE31|Myhre Syndrome|Recurrent Respiratory Papillomatosis|Laryngeal Papillomatosis|Tracheal Papillomatosis|Refsum Disease|Nicolaides Baraitser Syndrome|Leukodystrophy|Tango2|Cauda Equina Syndrome|Rare Gastrointestinal Disorders|Achalasia-Addisonian Syndrome|Achalasia Cardia|Achalasia Icrocephaly Syndrome|Anal Fistula|Congenital Sucrase-Isomaltase Deficiency|Eosinophilic Gastroenteritis|Idiopathic Gastroparesis|Hirschsprung Disease|Rare Inflammatory Bowel Disease|Intestinal Pseudo-Obstruction|Scleroderma|Short Bowel Syndrome|Sacral Agenesis|Sacral Agenesis Syndrome|Caudal Regression|Scheuermann Disease|SMC1A Truncated Mutations (Causing Loss of Gene Function)|Cystinosis|Juvenile Nephropathic Cystinosis|Nephropathic Cystinosis|Kennedy Disease|Spinal Bulbar Muscular Atrophy|Warburg Micro Syndrome|Mucolipidoses|Mitochondrial Diseases|Mitochondrial Aminoacyl-tRNA Synthetases|Mt-aaRS Disorders|Hypertrophic Olivary Degeneration|Non-Ketotic Hyperglycinemia|Fish Odor Syndrome|Halitosis|Isolated Congenital Asplenia|Lambert Eaton (LEMS)|Biliary Atresia|STAG1 Gene Mutation|Coffin Lowry Syndrome|Borjeson-Forssman-Lehman Syndrome|Blau Syndrome|Arginase 1 Deficiency|HSPB8 Myopathy|Beta-Mannosidosis|TBX4 Syndrome|DHDDS Gene Mutations|MAND-MBD5-Associated Neurodevelopmental Disorder|Constitutional Mismatch Repair Deficiency (CMMRD)|SPATA5 Disorder|SPATA5L1 Related Disorder |
| NCT01096901 | Choose to Lose for Women-Weight Loss to Reduce Breast Cancer Risk Factors | https://clinicaltrials.gov/study/NCT01096901 | CTL | COMPLETED | Obesity|Overweight |
| NCT02224807 | Effects of Diet and Exercise on Ductal Carcinoma in Situ | https://clinicaltrials.gov/study/NCT02224807 | DCIS | COMPLETED | Ductal Carcinoma In Situ|Breast Cancer |
| NCT04300478 | Appetite and Exercise in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04300478 | EARNESt | COMPLETED | Overweight|Breast Cancer|Obesity |
| NCT03824145 | Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer | https://clinicaltrials.gov/study/NCT03824145 | EDC | RECRUITING | Metastatic Breast Cancer |
| NCT01112839 | Reducing Breast Cancer Recurrence With Weight Loss | https://clinicaltrials.gov/study/NCT01112839 | ENERGY | COMPLETED | Breast Cancer|Overweight|Obesity |
| NCT01498536 | Effect of Diet and Exercise in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01498536 | F4F tri neg | COMPLETED | Breast Cancer|Obesity |
| NCT06504914 | Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT06504914 | FIM-BCS | RECRUITING | Hypertension|Obesity|Nutrition, Healthy |
| NCT06518837 | Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer | https://clinicaltrials.gov/study/NCT06518837 | FITWISE | NOT_YET_RECRUITING | Hormone Receptor-Positive Breast Cancer|HER2-Negative Breast Cancer |
| NCT05193149 | Inspiratory Muscle Training in Obese Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT05193149 | IMOCS | RECRUITING | Cancer Survivors|Obesity|Breast Cancer |
| NCT06318507 | The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy | https://clinicaltrials.gov/study/NCT06318507 | IMPACT | RECRUITING | Breast Neoplasms |
| NCT01728506 | An Internet-based Weight Loss and Exercise Intervention for Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01728506 | iWEB | UNKNOWN | Breast Cancer |
| NCT01559194 | Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk | https://clinicaltrials.gov/study/NCT01559194 | LEAF | COMPLETED | Breast Cancer|Weight Loss |
| NCT02681965 | A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT02681965 | LEAN3 | COMPLETED | Breast Cancer Survivorship|Obesity |
| NCT02255240 | LEVEL UP: Video Games for Activity in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT02255240 | LEVEL UP | WITHDRAWN | Breast Cancer|Obesity |
| NCT01896050 | Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer | https://clinicaltrials.gov/study/NCT01896050 | LOGRIBMET | COMPLETED | Breast Cancer|Arthralgia|Obesity |
| NCT01630499 | My Lifestyle Intervention of Food and Exercise | https://clinicaltrials.gov/study/NCT01630499 | MyLIFE | COMPLETED | Breast Cancer |
| NCT02273206 | Collaborative Care to Reduce Depression and Increase Cancer Screening Among Low-Income Urban Women | https://clinicaltrials.gov/study/NCT02273206 | PCM3 | COMPLETED | Depression|Breast Cancer Screening|Cervical Cancer Screening|Colorectal Cancer Screening |
| NCT00782366 | Predictive Genetic Risk Assessment Trial | https://clinicaltrials.gov/study/NCT00782366 | PGT | COMPLETED | Colon Cancer|Lung Cancer|Atrial Fibrillation|Diabetes Type 2|Obesity|Breast Cancer|Graves Disease|Osteoarthritis|Celiac Disease|Myocardial Infarction|Prostate Cancer |
| NCT02152462 | Exergaming Intervention and Breast Cancer Biomarkers in Black Women | https://clinicaltrials.gov/study/NCT02152462 | POWER | COMPLETED | Breast Cancer|Obesity |
| NCT05048108 | Remote Assessment of Cognition, Insulin Resistance and Omega-3 Fatty Acid Biomarkers in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT05048108 | RACIRO-3 | ACTIVE_NOT_RECRUITING | Breast Cancer|Obesity |
| NCT05848856 | The RISC Registry--Risk Informed Screening Registry | https://clinicaltrials.gov/study/NCT05848856 | RISC | NOT_YET_RECRUITING | Breast Cancer Risk|Cardiovascular Disease Risk|Cardiometabolic Risk|Diabetes |
| NCT04326660 | SCOPE-Chinese Women Study | https://clinicaltrials.gov/study/NCT04326660 | SCOPE | COMPLETED | Cancer, Breast|Obesity, Abdominal |
| NCT00774371 | Weight Reduction Intervention for Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT00774371 | SHAPE | COMPLETED | Breast Cancer |
| NCT02341235 | Self-monitoring Activity: a Randomized Trial of Game-oriented Applications | https://clinicaltrials.gov/study/NCT02341235 | SMARTGOAL | COMPLETED | Breast Cancer|Obesity |
| NCT02431676 | Survivorship Promotion In Reducing IGF-1 Trial | https://clinicaltrials.gov/study/NCT02431676 | SPIRIT | COMPLETED | Breast Cancer|Prostate Cancer|Lung Cancer|Colon Cancer|Melanoma of Skin|Endometrial Cancer|Liver Cancer|Pancreatic Cancer|Rectal Cancer|Kidney Cancer|Other Solid Malignant Tumors |
| NCT04965246 | Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04965246 | TALIEHO | RECRUITING | Inflammation|Cognitive Impairment|Anxiety|Alcohol Drinking |
| NCT04855552 | Telehealth Weight Loss Program for Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT04855552 | TWL | ACTIVE_NOT_RECRUITING | Cancer Survivors|Cancer of Breast|Body Weight|Overweight and Obesity |
| NCT01482702 | Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01482702 | VCC0910 | COMPLETED | Overweight|Postmenopausal|Breast Cancer |
| NCT01240213 | Vitamin D, Diet and Activity Study | https://clinicaltrials.gov/study/NCT01240213 | ViDA | COMPLETED | Breast Cancer|Obesity|Hypovitaminosis D |
| NCT00393172 | Women in Steady Exercise Research [Formerly Women, Oxidative Stress, Exercise and Estrogens (WOSEE)] | https://clinicaltrials.gov/study/NCT00393172 | WISER | COMPLETED | Breast Cancer|Obesity |
| NCT01515124 | The Women In Steady Exercise Research (WISER) Survivor Trial | https://clinicaltrials.gov/study/NCT01515124 | WISER Survivor | COMPLETED | Lymphedema |
| NCT00476203 | Yoga Study in Breast Cancer Patients | https://clinicaltrials.gov/study/NCT00476203 | Yoga | COMPLETED | Breast Cancer |
New and existing studies added or modified at clinicaltrials.gov
Recent Breast Cancer News
Breast Cancer Reviews
To see all 186 Reviews, go directly to PubMed.
REVIEWS from PubMed – July 5, 2024 – Obesity AND Cancer AND Breast AND Review
- Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer: ASCO Guideline Update April 10, 2025PURPOSE: To update the ASCO evidence-based recommendations on the use of sentinel lymph node biopsy (SLNB) in patients with early-stage breast cancer treated with initial surgery.Ko Un Park
- Obesity and Risk of Pre- and Postmenopausal Breast Cancer in Africa: A Systematic Review March 26, 2025Background and Aims: Several epidemiological studies have investigated the relationship between anthropometric factors and breast cancer (BC), but the results, particularly for premenopausal BC, remain inconsistent and contradictory. The aim of this systematic review is to present an overview of studies examining the association between obesity and BC risk in African women, by menopausal status. […]Najia Mane
- Obesity, Physical Activity, and Cancer Incidence in Two Geographically Distinct Populations; The Gulf Cooperation Council Countries and the United Kingdom-A Systematic Review and Meta-Analysis January 8, 2025CONCLUSION: Although both regions share similarities, advanced healthcare systems, genetic characteristics, dietary habits, and cultural practices may influence cancer incidence and types.Christine Gaskell
- Metabolic syndrome is associated with breast cancer mortality: A systematic review and meta-analysis January 8, 2025CONCLUSIONS: Among BC survivors, metabolic syndrome was associated with inferior BC outcomes. This necessitates the creation of clinical guidelines that include metabolic screening for BC survivors. Further research should identify effective interventions to reduce the prevalence of metabolic syndrome among BC survivors to improve metabolic health and BC outcomes.Sixten Harborg
- From Micro to Macro: Understanding the Far-Reaching Consequences of B12 Deficiency on Women's Health January 3, 2025CONCLUSION: The search produced 28 full-text articles. B12 deficiency prevalence among women identified by the selected studies ranges from 0.6% to 45.5%. The deficiency of B12 is connected with the risk for depression/post-partum depression, breast cancer, recurrent pregnancy loss, gestational diabetes mellitus, insulin resistance, and obesity among women. It is necessary to monitor and correct […]Betsy Sara Zacharias
- Impact of sarcopenic obesity on postoperative outcomes in patients with oesophago-gastric cancer: A systematic review and meta-analysis December 26, 2024CONCLUSIONS: Sarcopenic obesity worsens OS and increases the risk of postoperative complications in patients with oesophago-gastric cancer undergoing radical resection.Ryota Matsui
- Modifiable Risk Factors for Breast Cancer: Insights From Systematic Reviews December 23, 2024CONCLUSION: Our findings suggest that a high-fat diet, low intake of dietary fiber, alcohol consumption, smoking, and obesity are linked to a higher risk of breast cancer. Conversely, physical activity and breastfeeding appear to lower breast cancer risk. However, the methodological and evidence quality of the reviewed studies was generally low, necessitating caution in the […]Xuehua Li
- Can exercise as a complementary technique manage inflammatory markers in women with breast cancer who are overweight and obese? A systematic review and meta-analysis December 22, 2024CONCLUSION: Exercise significantly reduced CRP, IL-6, and leptin levels and overall increased adiponectin levels in women with overweight obese, and breast cancer. However, the effects on TNF-α and IL-10 levels were not significant. CE may be the most recommended type of exercise for reducing pro-inflammatory factors and increasing anti-inflammatory factors. Therefore, this study considers exercise […]Liang Tan
- Disparities in Breast Reconstruction After Mastectomy in Southeast Asia: A Systematic Review December 10, 2024Breast cancer is the most commonly diagnosed cancer among women in Southeast Asia. However, significant disparities in access to postmastectomy breast reconstruction persist due to cultural, economic, and healthcare-related factors. These disparities result in unequal access to care, impacting patient outcomes, and overall quality of life. A systematic review was conducted following PRISMA guidelines to […]Antoinette Nguyen
- Gut microbiota and breast cancer: systematic review and meta-analysis December 9, 2024CONCLUSIONS: The study found a significant difference in gut microbiota diversity between women with breast cancer and controls, supporting the growing evidence that the gut microbiota may play a role in mammary carcinogenesis.Guilherme Gamba
- Association between metabolic and bariatric surgery and malignancy: a systematic review, meta-analysis, trends, and conclusions November 24, 2024CONCLUSIONS: According to the data retrieved from patients who underwent MBS compared to nonoperated patients suffering from obesity, the overall risk for malignancy was lower in the MBS group. Additional information collected in this study revealed the behavior of specific types of cancer in response to induced weight loss by operative means. The benefit of […]Libi-Or Madar
- Long-Term Randomized Controlled Trials of Diet Intervention Reports and Their Impact on Cancer: A Systematic Review October 16, 2024CONCLUSIONS: More long-term RCTs evaluating cancer and cancer-related biomarker endpoints are needed, especially for cancers at sites other than the breast.Edward R Sauter
- Association of metabolic obesity phenotypes with risk of overall and site-specific cancers: a systematic review and meta-analysis of cohort studies September 24, 2024CONCLUSION: These findings suggest that both higher adiposity and metabolic dysfunction were independently associated with increased risk of several cancers, with the strongest associations generally observed among those with both metabolic dysfunction and obesity.Yahya Mahamat-Saleh
- An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals August 26, 2024Background: Epidemiological research investigating the impact of exposure to plastics, and plastic-associated chemicals, on human health is critical, especially given exponentially increasing plastic production. In parallel with increasing production, academic research has also increased exponentially both in terms of the primary literature and ensuing systematic reviews with meta-analysis. However, there are few overviews that capture […]Christos Symeonides
- The effects of green exercise on the mental and physical health of people with chronic conditions: a systematic review August 21, 2024Green exercise, defined as physical activity in natural settings, shows promise for enhancing exercise participation and improving health. This systematic review aimed to assess the effectiveness of green exercise in people with chronic conditions. Seven electronic databases were searched and of the 7801 screened articles, 14 trials met the inclusion criteria. Green exercise was a […]Aristi Tsokani
Obesity Breast Cancer Papers
To see all >777 Papers, go directly to PubMed.
RECENT PAPERS from PubMed – July 5, 2024 – Obesity (in title) AND Cancer (in title) AND Breast (in title)
- Insights into the molecular and genetic role of obesity in breast cancer pathogenesis May 12, 2025The epidemic of obesity is a growing concern and is one of the major risk factors for several chronic diseases, including several types of cancers. The correlation of breast cancer with obesity has been extensively studied and involves an interplay of hormonal, metabolic, and genetic factors explored in this review. Inflammation and hormone dysregulation play […]Sandeep Mallya
- The impact of obesity on the outcomes of complex decongestive therapy among patients with breast cancer-related lymphedema April 24, 2025CONCLUSION: The influence of CDT on decreasing volume and improving functionality was comparable between obese and nonobese patients with BCRL; however, obesity may negatively impact CDT outcomes concerning quality of life issues.Aysegul Yaman
- The Impact of Obesity on Treatment Outcomes in Patients with Hormone Receptor-Positive HER2-Negative Metastatic Breast Cancer Receiving CDK 4/6 Inhibitors April 17, 2025CONCLUSION: While BMI-defined obesity showed slight PFS improvement with CDK 4/6 inhibitors and endocrine therapy, using VAT to define obesity revealed significant PFS gains. This highlights the need for further research on biomarker to clarify the role of adiposity in MBC, which may differ from its impact in EBC.Yoo Bin Jung
- Weight Management Experiences Among People Affected by Overweight and Obesity Who Are Living With and Beyond Colorectal, Breast or Prostate Cancer: A Cross-Sectional Survey April 16, 2025CONCLUSIONS: This suggests that the receipt of weight management advice may encourage people LWBC who are affected by overweight and obesity to engage with WMPs.William Goodman
- Obesity, overweight and breast cancer: new clinical data and implications for practice April 11, 2025Excess bodyweight has negative consequences in breast cancer (BC) patients, significantly increasing the incidence of BC and adversely affecting clinical outcomes in most BC subtypes. This article overviews recent evidence relating to excess bodyweight (particularly obesity) and its effect on treatment in women with BC, focusing on latest evidence, including clinical findings from recently introduced […]Laura García-Estévez
- Genetic Insights into Breast Cancer in Northeastern Mexico: Unveiling Gene-Environment Interactions and Their Links to Obesity and Metabolic Diseases March 28, 2025Background: Breast cancer (BC), one of the most common cancers, has increased in Mexico during the past decade, along with other chronic and metabolic diseases. Methods: Herein, we analyzed 121 SNPs (85 SNPs related to BC and/or glucose-associated metabolic pathways and 36 SNP classified as ancestry markers) in 92 confirmed BC cases and 126 unaffected […]Hugo Leonid Gallardo-Blanco
- Exploring Urtica dioica L. as a Promising Alternative Therapy for Obesity-Related Breast Cancer: Insights from Molecular Mechanisms and Bioinformatic Analysis March 28, 2025Obesity and obesity-related breast cancer are major health problems that require alternative treatment strategies. Urtica dioica L. (U. dioica) stands out as a potential therapeutic candidate with its anti-oxidant, anti-cancer and lipid-lowering properties. In this study, the molecular effects of U. dioica were investigated by gene expression analysis and molecular docking methods. U. dioica significantly […]Ayla Eren
- EPR25-115: Pre-Menopausal Obesity Duration and Breast Cancer Risk in Women With Family History of Breast Malignancy March 28, 2025No abstractMaria Reyes-Matos
- Nutritional ketosis modulates the methylation of cancer-related genes in patients with obesity and in breast cancer cells March 27, 2025Scientific evidence demonstrates that a very low-calorie ketogenic diet (VLCKD) is effective and beneficial in the treatment of obesity, capable of reversing the methylome associated with obesity and has immunomodulatory capacity. This effect is in part promoted by nutritional ketosis and could be involved in counteracting obesity-related cancer. The aim of this study was to […]Paula M Lorenzo
- Obesity and Risk of Pre- and Postmenopausal Breast Cancer in Africa: A Systematic Review March 26, 2025Background and Aims: Several epidemiological studies have investigated the relationship between anthropometric factors and breast cancer (BC), but the results, particularly for premenopausal BC, remain inconsistent and contradictory. The aim of this systematic review is to present an overview of studies examining the association between obesity and BC risk in African women, by menopausal status. […]Najia Mane
- Impact of obesity on doxorubicin pharmacokinetics in women with breast cancer March 13, 2025IntroductionExperts suggest doxorubicin clearance is decreased in women with a body mass index (BMI) of ≥35 kg/m². However, few data support this recommendation.MethodsWomen receiving doxorubicin for breast cancer in three BMI groups were recruited (n = 15). Doxorubicin dosing was determined by body surface area and was administered by 30-min intravenous infusion. Blood samples were […]Ronald G Hall
- Metabolic and transcriptional effects of bazedoxifene/conjugated estrogens in a model of obesity-associated breast cancer risk March 6, 2025Many risk-eligible women refuse tamoxifen for primary prevention of breast cancer due to concerns about common side effects such as vasomotor symptoms. Tamoxifen may also induce or worsen insulin resistance and hypertriglyceridemia, especially in women with obesity. The combination of bazedoxifene and conjugated estrogens (BZA/CE) reduces vasomotor symptoms and is currently undergoing evaluation for breast […]Erin D Giles
- Glutathione peroxidase 4 (GPX4) and obesity interact to impact tumor progression and treatment response in triple negative breast cancer February 26, 2025INTRODUCTION: Triple-negative breast cancer (TNBC), which tends to be more advanced when diagnosed and more aggressive than other breast cancer subtypes, is accelerated by obesity. Hypertrophic adipocytes and cancer cells exhibit increased oxidative stress and altered redox homeostasis, influencing therapeutic outcomes. Enzymes implicated in both redox regulation and TNBC include glutathione peroxidase 4 (GPX4; reduces […]Emily N Devericks
- Obesity and male breast cancer: a complementary perspective February 26, 2025No abstractRaúl Aguilera-Eguía
- Hyperlipidemia drives tumor growth in a mouse model of obesity-accelerated breast cancer growth February 24, 2025Obesity is an established risk factor for breast cancer (BC), yet the specific mechanisms driving this association remain unclear. Dysregulated lipid metabolism has emerged as a key factor in cancer cell biology. While obesity is often accompanied by hyperlipidemia, the isolated impact of elevated lipid levels on BC growth has not been experimentally tested. Using […]Renan Fl Vieira
- Knowledge and Awareness of Obesity-Related Breast Cancer Risk Among Women in the Qassim Region, Saudi Arabia: A Cross-Sectional Study February 13, 2025Background: Breast cancer (BC) is a major health concern globally and the second leading cause of cancer-related mortality in women in Saudi Arabia. Although peoples' awareness of BC risk factors has been previously examined, studies on obesity-related BC awareness in the Qassim region are inconclusive. We aimed to evaluate knowledge and awareness of obesity-related BC […]Amal Mohamad Husein Mackawy
- Obesity-Related Inflammation Reduces Treatment Sensitivity and Promotes Aggressiveness in Luminal Breast Cancer Modulating Oxidative Stress and Mitochondria January 8, 2025CONCLUSIONS: Taken together, our findings suggest that antioxidant and mitochondrial markers are key factors that reduce treatment sensitivity in obesity-related luminal breast cancer. The identified biomarkers may serve as valuable tools for the prognosis and development of more effective therapies in these patients.Pere Miquel Morla-Barcelo
- Obesity Is an Independent Prognostic Factor That Reduced Pathological Complete Response in Operable Breast Cancer Patients January 8, 2025Background and Objectives: Obesity is a significant risk factor for the development of breast cancer (BC) and associated poorer outcomes. A pathological complete response (pCR) with neoadjuvant chemotherapy (NACT) correlates with improved long-term prognosis in BC patients. In this study, we aimed to investigate the predictive effect of obesity on achieving pCR following NACT. Methods: […]Murad Guliyev
- General obesity, abdominal obesity, and the risk of cardiovascular disease including stroke in 5-year breast cancer survivors December 15, 2024CONCLUSIONS: Breast cancer survivors with higher BMI and/or abdominal obesity were associated with an elevated risk of CVD, including stroke.Ji Soo Kim
- The Interplay Between Obesity and Aging in Breast Cancer and Regulatory Function of MicroRNAs in This Pathway December 9, 2024Breast cancer (BC) is a significant contributor to cancer-related deaths in women, and it has complex connections with obesity and aging. This review explores the interaction between obesity and aging in relation to the development and progression of BC, focusing on the controlling role of microRNAs (miRNAs). Obesity, characterized by excess adipose tissue, contributes to […]Nima Mahdei Nasir Mahalleh
US Clinical Trials involving Breast Cancer and Obesity
(update March 24, 2024)
| NCT Number | Study Title | Study URL | Acronym | Study Status | Interventions | Sponsor | Collaborators | Enrollment | Study Type |
|---|---|---|---|---|---|---|---|---|---|
| NCT01302379 | Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT01302379 | COMPLETED | DRUG: Metformin|DRUG: Placebo|BEHAVIORAL: Lifestyle intervention|BEHAVIORAL: Standard printed dietary guidelines | University of California, San Diego | 333 | INTERVENTIONAL | ||
| NCT00933309 | The Impact of Obesity and Obesity Treatments on Breast Cancer | https://clinicaltrials.gov/study/NCT00933309 | COMPLETED | DRUG: Exemestane|DRUG: Avandamet | M.D. Anderson Cancer Center | Susan G. Komen Breast Cancer Foundation | 25 | INTERVENTIONAL | |
| NCT04720209 | Taking AIM at Breast Cancer | https://clinicaltrials.gov/study/NCT04720209 | RECRUITING | OTHER: CARE|OTHER: TARE|OTHER: Home-Based Stretching | Dana-Farber Cancer Institute | National Cancer Institute (NCI) | 300 | INTERVENTIONAL | |
| NCT04913064 | Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer | https://clinicaltrials.gov/study/NCT04913064 | RECRUITING | OTHER: Questionnaire Administration|DRUG: White Button Mushroom Extract | City of Hope Medical Center | National Cancer Institute (NCI) | 26 | INTERVENTIONAL | |
| NCT06318507 | The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy | https://clinicaltrials.gov/study/NCT06318507 | IMPACT | RECRUITING | COMBINATION_PRODUCT: Fecal microbial diversity | Pennington Biomedical Research Center | 25 | OBSERVATIONAL | |
| NCT02750826 | Breast Cancer WEight Loss Study (BWEL Study) | https://clinicaltrials.gov/study/NCT02750826 | ACTIVE_NOT_RECRUITING | OTHER: Health Education Program|OTHER: Weight Loss Intervention | Alliance for Clinical Trials in Oncology | National Cancer Institute (NCI)|Division of Cancer Control|NIH Biomarker, Imaging and Quality of Life Studies Funding Program (BIQSFP)|Canadian Cancer Trials Group | 3177 | INTERVENTIONAL | |
| NCT03779867 | Acute Exercise Intervention in Breast Cancer Survivors | https://clinicaltrials.gov/study/NCT03779867 | ACE | ACTIVE_NOT_RECRUITING | BEHAVIORAL: Exercise Intervention|OTHER: Resting|OTHER: Biomarker Analysis|OTHER: Questionnaire Administration | Fred Hutchinson Cancer Center | Breast Cancer Research Foundation | 105 | INTERVENTIONAL |
| NCT03091842 | Exercise Intervention in Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer | https://clinicaltrials.gov/study/NCT03091842 | WITHDRAWN | BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Informational Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration | University of Southern California | National Cancer Institute (NCI) | 0 | INTERVENTIONAL | |
| NCT04003038 | Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery | https://clinicaltrials.gov/study/NCT04003038 | RECRUITING | PROCEDURE: Negative Pressure Wound Therapy|PROCEDURE: Wound Care Management | M.D. Anderson Cancer Center | National Cancer Institute (NCI) | 80 | INTERVENTIONAL | |
| NCT06399276 | 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity | https://clinicaltrials.gov/study/NCT06399276 | NOT_YET_RECRUITING | BEHAVIORAL: Weight Loss | University of Colorado, Denver | National Cancer Institute (NCI) | 36 | INTERVENTIONAL |