Breast – COC.org

Breast Cancer - News, Obesity Reviews, Recent Papers, and Clinical Trials

Dehesh T, Fadaghi S, Seyedi M, Abolhadi E, Ilaghi M, Shams P, Ajam F, Mosleh-Shirazi MA, Dehesh P. The relation between obesity and breast cancer risk in women by considering menstruation status and geographical variations: a systematic review and meta-analysis. BMC Womens Health. 2023 Jul 26;23(1):392. doi: 10.1186/s12905-023-02543-5. PMID: 37496015; PMCID: PMC10373406.

Summary

This research paper explores the relationship between obesity and breast cancer risk in women, taking into account both pre- and post-menopausal status as well as geographical variations. Using a meta-analysis of over 100 studies, researchers discovered that obesity appears to have a protective effect against breast cancer in pre-menopausal women, particularly in European women, while in post-menopausal women, obesity increases the risk of developing breast cancer across various continents. The researchers also identified factors that contributed to the heterogeneity observed across the studies, such as study design, geographical location, and hormonal drug use.

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Current 27 Clinical Trials in Obesity and Breast Cancer at 41 sites in the United States (Recruiting or Not Yet Recruting)

NCT Number	Study Title	Study Status	Conditions	Sponsor
NCT06517212	Tirzepatide in Patients With Obesity or Overweight Who Have High Risk Early Breast Cancer and Are ctDNA+	NOT_YET_RECRUITING	Breast Cancer\|Breast Neoplasms	Baylor Research Institute
NCT04720209	Taking AIM at Breast Cancer	RECRUITING	Breast Cancer\|Breast Cancer Stage I\|Breast Cancer Stage II\|Breast Cancer Stage III	Dana-Farber Cancer Institute
NCT04913064	Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer	RECRUITING	Breast Carcinoma	City of Hope Medical Center
NCT06318507	The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy	RECRUITING	Breast Neoplasms	Pennington Biomedical Research Center
NCT04003038	Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery	RECRUITING	Body Mass Index Greater Than or Equal to 30\|Malignant Breast Neoplasm\|Mammoplasty Patient\|Obesity	M.D. Anderson Cancer Center
NCT06399276	4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity	RECRUITING	Breast Cancer	University of Colorado, Denver
NCT05193149	Inspiratory Muscle Training in Obese Breast Cancer Survivors	RECRUITING	Cancer Survivors\|Obesity\|Breast Cancer	Ohio State University Comprehensive Cancer Center
NCT02095184	GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese Patients	RECRUITING	Breast Cancer	University of Maryland, Baltimore
NCT06485089	Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers	RECRUITING	Obesity\|Breast Cancer Risk	University of Kansas Medical Center
NCT03824145	Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer	RECRUITING	Metastatic Breast Cancer	Medical College of Wisconsin
NCT06518837	Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer	NOT_YET_RECRUITING	Hormone Receptor-Positive Breast Cancer\|HER2-Negative Breast Cancer	Rutgers, The State University of New Jersey
NCT06106477	Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer	RECRUITING	Breast Cancer	Medical College of Wisconsin
NCT03712813	Effect of Low Intensity Vibration (LIV) on Aromatase Inhibitor- Induced Musculoskeletal Dysfunction in Early Stage Breast Cancer Survivors	RECRUITING	Breast Cancer	Indiana University
NCT04365569	Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program	RECRUITING	Breast Cancer	Case Comprehensive Cancer Center
NCT04717050	Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity	RECRUITING	Breast Cancer\|Coronary Artery Disease\|Stroke\|Type2 Diabetes	Dana-Farber Cancer Institute
NCT06195306	Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction	NOT_YET_RECRUITING	Breast Atypical Hyperplasia\|Breast Carcinoma\|Breast Ductal Carcinoma In Situ\|Breast Lobular Carcinoma In Situ	National Cancer Institute (NCI)
NCT05386719	Cardiometabolic Screening Program	RECRUITING	Breast Cancer\|Early-stage Breast Cancer	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05780814	The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer	RECRUITING	Breast Cancer\|Insomnia\|Weight Gain	Johns Hopkins University
NCT05930483	Remotely Delivered, Culturally Tailored Weight Loss Interventions Among Latina Breast Cancer Survivors	NOT_YET_RECRUITING	Anatomic Stage I Breast Cancer AJCC v8\|Anatomic Stage II Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8	Fred Hutchinson Cancer Center
NCT06504914	Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors	RECRUITING	Hypertension\|Obesity\|Nutrition, Healthy	University of Illinois at Chicago
NCT05721976	With Love, Grandma ("Con Cariño, Abuelita") Pilot Study	RECRUITING	Cancer, Breast\|Cancer, Uterus\|Cancer, Ovary\|Obesity\|Activity, Motor\|Diet, Healthy	University of Miami Sylvester Comprehensive Cancer Center
NCT06315296	An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer	RECRUITING	Anatomic Stage IV Breast Cancer AJCC v8\|Metastatic Breast Carcinoma\|Metastatic Lung Carcinoma\|Metastatic Malignant Neoplasm in the Brain\|Stage IV Lung Cancer AJCC v8	Thomas Jefferson University
NCT04965246	Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors	RECRUITING	Inflammation\|Cognitive Impairment\|Anxiety\|Alcohol Drinking	Milton S. Hershey Medical Center
NCT05848856	The RISC Registry--Risk Informed Screening Registry	NOT_YET_RECRUITING	Breast Cancer Risk\|Cardiovascular Disease Risk\|Cardiometabolic Risk\|Diabetes	Precision Health Equity Initiative
NCT06123286	Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms	NOT_YET_RECRUITING	Breast Cancer\|Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)\|Joint Pain	Philip Chang
NCT06171945	Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors	RECRUITING	Cancer\|Physical Activity\|Cancer Survivorship\|Mental Health\|Obesity	UNC Lineberger Comprehensive Cancer Center
NCT01793168	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	RECRUITING	Rare Disorders\|Undiagnosed Disorders\|Disorders of Unknown Prevalence\|Cornelia De Lange Syndrome\|Prenatal Benign Hypophosphatasia\|Perinatal Lethal Hypophosphatasia\|Odontohypophosphatasia\|Adult Hypophosphatasia\|Childhood-onset Hypophosphatasia\|Infantile Hypophosphatasia\|Hypophosphatasia\|Kabuki Syndrome\|Bohring-Opitz Syndrome\|Narcolepsy Without Cataplexy\|Narcolepsy-cataplexy\|Hypersomnolence Disorder\|Idiopathic Hypersomnia Without Long Sleep Time\|Idiopathic Hypersomnia With Long Sleep Time\|Idiopathic Hypersomnia\|Kleine-Levin Syndrome\|Kawasaki Disease\|Leiomyosarcoma\|Leiomyosarcoma of the Corpus Uteri\|Leiomyosarcoma of the Cervix Uteri\|Leiomyosarcoma of Small Intestine\|Acquired Myasthenia Gravis\|Addison Disease\|Hyperacusis (Hyperacousis)\|Juvenile Myasthenia Gravis\|Transient Neonatal Myasthenia Gravis\|Williams Syndrome\|Lyme Disease\|Myasthenia Gravis\|Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome)\|Isolated Klippel-Feil Syndrome\|Frasier Syndrome\|Denys-Drash Syndrome\|Beckwith-Wiedemann Syndrome\|Emanuel Syndrome\|Isolated Aniridia\|Axenfeld-Rieger Syndrome\|Aniridia-intellectual Disability Syndrome\|Aniridia - Renal Agenesis - Psychomotor Retardation\|Aniridia - Ptosis - Intellectual Disability - Familial Obesity\|Aniridia - Cerebellar Ataxia - Intellectual Disability\|Aniridia - Absent Patella\|Aniridia\|Peters Anomaly - Cataract\|Peters Anomaly\|Potocki-Shaffer Syndrome\|Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11\|Silver-Russell Syndrome Due to Imprinting Defect of 11p15\|Silver-Russell Syndrome Due to 11p15 Microduplication\|Syndromic Aniridia\|WAGR Syndrome\|Wolf-Hirschhorn Syndrome\|4p16.3 Microduplication Syndrome\|4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome\|Autosomal Recessive Stickler Syndrome\|Stickler Syndrome Type 2\|Stickler Syndrome Type 1\|Stickler Syndrome\|Mucolipidosis Type 4\|X-linked Spinocerebellar Ataxia Type 4\|X-linked Spinocerebellar Ataxia Type 3\|X-linked Intellectual Disability - Ataxia - Apraxia\|X-linked Progressive Cerebellar Ataxia\|X-linked Non Progressive Cerebellar Ataxia\|X-linked Cerebellar Ataxia\|Vitamin B12 Deficiency Ataxia\|Toxic Exposure Ataxia\|Unclassified Autosomal Dominant Spinocerebellar Ataxia\|Thyroid Antibody Ataxia\|Sporadic Adult-onset Ataxia of Unknown Etiology\|Spinocerebellar Ataxia With Oculomotor Anomaly\|Spinocerebellar Ataxia With Epilepsy\|Spinocerebellar Ataxia With Axonal Neuropathy Type 2\|Spinocerebellar Ataxia Type 8\|Spinocerebellar Ataxia Type 7\|Spinocerebellar Ataxia Type 6\|Spinocerebellar Ataxia Type 5\|Spinocerebellar Ataxia Type 4\|Spinocerebellar Ataxia Type 37\|Spinocerebellar Ataxia Type 36\|Spinocerebellar Ataxia Type 35\|Spinocerebellar Ataxia Type 34\|Spinocerebellar Ataxia Type 32\|Spinocerebellar Ataxia Type 31\|Spinocerebellar Ataxia Type 30\|Spinocerebellar Ataxia Type 3\|Spinocerebellar Ataxia Type 29\|Spinocerebellar Ataxia Type 28\|Spinocerebellar Ataxia Type 27\|Spinocerebellar Ataxia Type 26\|Spinocerebellar Ataxia Type 25\|Spinocerebellar Ataxia Type 23\|Spinocerebellar Ataxia Type 22\|Spinocerebellar Ataxia Type 21\|Spinocerebellar Ataxia Type 20\|Spinocerebellar Ataxia Type 2\|Spinocerebellar Ataxia Type 19/22\|Spinocerebellar Ataxia Type 18\|Spinocerebellar Ataxia Type 17\|Spinocerebellar Ataxia Type 16\|Spinocerebellar Ataxia Type 15/16\|Spinocerebellar Ataxia Type 14\|Spinocerebellar Ataxia Type 13\|Spinocerebellar Ataxia Type 12\|Spinocerebellar Ataxia Type 11\|Spinocerebellar Ataxia Type 10\|Spinocerebellar Ataxia Type 1 With Axonal Neuropathy\|Spinocerebellar Ataxia Type 1\|Spinocerebellar Ataxia - Unknown\|Spinocerebellar Ataxia - Dysmorphism\|Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature\|Spasticity-ataxia-gait Anomalies Syndrome\|Spastic Ataxia With Congenital Miosis\|Spastic Ataxia - Corneal Dystrophy\|Spastic Ataxia\|Rare Hereditary Ataxia\|Rare Ataxia\|Recessive Mitochondrial Ataxia Syndrome\|Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature\|Posterior Column Ataxia - Retinitis Pigmentosa\|Post-Stroke Ataxia\|Post-Head Injury Ataxia\|Post Vaccination Ataxia\|Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract\|Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus\|Non-hereditary Degenerative Ataxia\|Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity\|Olivopontocerebellar Atrophy - Deafness\|NARP Syndrome\|Myoclonus - Cerebellar Ataxia - Deafness\|Multiple System Atrophy, Parkinsonian Type\|Multiple System Atrophy, Cerebellar Type\|Multiple System Atrophy\|Maternally-inherited Leigh Syndrome\|Machado-Joseph Disease Type 3\|Machado-Joseph Disease Type 2\|Machado-Joseph Disease Type 1\|Leigh Syndrome\|Late-onset Ataxia With Dementia\|Infection or Post Infection Ataxia\|GAD Ataxia\|Hereditary Episodic Ataxia\|Gliadin/Gluten Ataxia\|Friedreich Ataxia\|Fragile X-associated Tremor/Ataxia Syndrome\|Familial Paroxysmal Ataxia\|Exposure to Medications Ataxia\|Episodic Ataxia With Slurred Speech\|Episodic Ataxia Unknown Type\|Episodic Ataxia Type 7\|Episodic Ataxia Type 6\|Episodic Ataxia Type 5\|Episodic Ataxia Type 4\|Episodic Ataxia Type 3\|Episodic Ataxia Type 1\|Epilepsy and/or Ataxia With Myoclonus as Major Feature\|Early-onset Spastic Ataxia-neuropathy Syndrome\|Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity\|Early-onset Cerebellar Ataxia With Retained Tendon Reflexes\|Early-onset Ataxia With Dementia\|Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia\|Dilated Cardiomyopathy With Ataxia\|Cataract - Ataxia - Deafness\|Cerebellar Ataxia, Cayman Type\|Cerebellar Ataxia With Peripheral Neuropathy\|Cerebellar Ataxia - Hypogonadism\|Cerebellar Ataxia - Ectodermal Dysplasia\|Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss\|Brain Tumor Ataxia\|Brachydactyly - Nystagmus - Cerebellar Ataxia\|Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia\|Autosomal Recessive Syndromic Cerebellar Ataxia\|Autosomal Recessive Spastic Ataxia With Leukoencephalopathy\|Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay\|Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria\|Autosomal Recessive Spastic Ataxia\|Autosomal Recessive Metabolic Cerebellar Ataxia\|Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine\|Autosomal Recessive Ataxia, Beauce Type\|Autosomal Recessive Ataxia Due to Ubiquinone Deficiency\|Autosomal Recessive Ataxia Due to PEX10 Deficiency\|Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia\|Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency\|Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency\|Autosomal Recessive Congenital Cerebellar Ataxia\|Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome\|Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity\|Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency\|Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect\|Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion\|Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation\|Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness\|Autosomal Recessive Cerebellar Ataxia\|Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly\|Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation\|Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy\|Autosomal Dominant Spastic Ataxia Type 1\|Autosomal Dominant Spastic Ataxia\|Autosomal Dominant Optic Atrophy\|Ataxia-telangiectasia Variant\|Ataxia-telangiectasia\|Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy\|Autosomal Dominant Cerebellar Ataxia Type 4\|Autosomal Dominant Cerebellar Ataxia Type 3\|Autosomal Dominant Cerebellar Ataxia Type 2\|Autosomal Dominant Cerebellar Ataxia Type 1\|Autosomal Dominant Cerebellar Ataxia\|Ataxia-telangiectasia-like Disorder\|Ataxia With Vitamin E Deficiency\|Ataxia With Dementia\|Ataxia - Oculomotor Apraxia Type 1\|Ataxia - Other\|Ataxia - Genetic Diagnosis - Unknown\|Acquired Ataxia\|Adult-onset Autosomal Recessive Cerebellar Ataxia\|Alcohol Related Ataxia\|Multiple Endocrine Neoplasia\|Multiple Endocrine Neoplasia Type II\|Multiple Endocrine Neoplasia Type 1\|Multiple Endocrine Neoplasia Type 2\|Multiple Endocrine Neoplasia, Type IV\|Multiple Endocrine Neoplasia, Type 3\|Multiple Endocrine Neoplasia (MEN) Syndrome\|Multiple Endocrine Neoplasia Type 2B\|Multiple Endocrine Neoplasia Type 2A\|Atypical Hemolytic Uremic Syndrome\|Atypical HUS\|Wiedemann-Steiner Syndrome\|Breast Implant-Associated Anaplastic Large Cell Lymphoma\|Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)\|Hemophagocytic Lymphohistiocytosis\|Behcet's Disease\|Alagille Syndrome\|Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD)\|Lowe Syndrome\|Pitt Hopkins Syndrome\|1p36 Deletion Syndrome\|Jansen Type Metaphyseal Chondrodysplasia\|Cockayne Syndrome\|Chronic Recurrent Multifocal Osteomyelitis\|CRMO\|Malan Syndrome\|Hereditary Sensory and Autonomic Neuropathy Type Ie\|VCP Disease\|Hypnic Jerking\|Sleep Myoclonus\|Mollaret Meningitis\|Recurrent Viral Meningitis\|CRB1\|Leber Congenital Amaurosis\|Retinitis Pigmentosa\|Rare Retinal Disorder\|KCNMA1-Channelopathy\|Primary Biliary Cirrhosis\|ZMYND11\|Transient Global Amnesia\|Glycogen Storage Disease\|Alstrom Syndrome\|White Sutton Syndrome\|DNM1\|EIEE31\|Myhre Syndrome\|Recurrent Respiratory Papillomatosis\|Laryngeal Papillomatosis\|Tracheal Papillomatosis\|Refsum Disease\|Nicolaides Baraitser Syndrome\|Leukodystrophy\|Tango2\|Cauda Equina Syndrome\|Rare Gastrointestinal Disorders\|Achalasia-Addisonian Syndrome\|Achalasia Cardia\|Achalasia Icrocephaly Syndrome\|Anal Fistula\|Congenital Sucrase-Isomaltase Deficiency\|Eosinophilic Gastroenteritis\|Idiopathic Gastroparesis\|Hirschsprung Disease\|Rare Inflammatory Bowel Disease\|Intestinal Pseudo-Obstruction\|Scleroderma\|Short Bowel Syndrome\|Sacral Agenesis\|Sacral Agenesis Syndrome\|Caudal Regression\|Scheuermann Disease\|SMC1A Truncated Mutations (Causing Loss of Gene Function)\|Cystinosis\|Juvenile Nephropathic Cystinosis\|Nephropathic Cystinosis\|Kennedy Disease\|Spinal Bulbar Muscular Atrophy\|Warburg Micro Syndrome\|Mucolipidoses\|Mitochondrial Diseases\|Mitochondrial Aminoacyl-tRNA Synthetases\|Mt-aaRS Disorders\|Hypertrophic Olivary Degeneration\|Non-Ketotic Hyperglycinemia\|Fish Odor Syndrome\|Halitosis\|Isolated Congenital Asplenia\|Lambert Eaton (LEMS)\|Biliary Atresia\|STAG1 Gene Mutation\|Coffin Lowry Syndrome\|Borjeson-Forssman-Lehman Syndrome\|Blau Syndrome\|Arginase 1 Deficiency\|HSPB8 Myopathy\|Beta-Mannosidosis\|TBX4 Syndrome\|DHDDS Gene Mutations\|MAND-MBD5-Associated Neurodevelopmental Disorder\|Constitutional Mismatch Repair Deficiency (CMMRD)\|SPATA5 Disorder\|SPATA5L1 Related Disorder	Sanford Health

Clinical Trials

Breast Cancer Clinical Trials in the United States that involve obesity – Total of 130 (October 7, 2024)

https://clinicaltrials.gov/search?locStr=United%20States&country=United%20States&cond=Breast%20Cancer&term=Obesity

NCT Number	Study Title	Study URL	Acronym	Study Status	Conditions
NCT01302379	Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01302379		COMPLETED	Breast Neoplasms
NCT00933309	The Impact of Obesity and Obesity Treatments on Breast Cancer	https://clinicaltrials.gov/study/NCT00933309		COMPLETED	Breast Cancer
NCT06517212	Tirzepatide in Patients With Obesity or Overweight Who Have High Risk Early Breast Cancer and Are ctDNA+	https://clinicaltrials.gov/study/NCT06517212		NOT_YET_RECRUITING	Breast Cancer\|Breast Neoplasms
NCT04720209	Taking AIM at Breast Cancer	https://clinicaltrials.gov/study/NCT04720209		RECRUITING	Breast Cancer\|Breast Cancer Stage I\|Breast Cancer Stage II\|Breast Cancer Stage III
NCT04913064	Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer	https://clinicaltrials.gov/study/NCT04913064		RECRUITING	Breast Carcinoma
NCT02750826	Breast Cancer WEight Loss Study (BWEL Study)	https://clinicaltrials.gov/study/NCT02750826		ACTIVE_NOT_RECRUITING	Breast Carcinoma
NCT03091842	Exercise Intervention in Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer	https://clinicaltrials.gov/study/NCT03091842		WITHDRAWN	Cancer Survivor\|Central Obesity\|Estrogen Receptor Positive\|Postmenopausal\|Progesterone Receptor Positive\|Stage I Breast Cancer\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage II Breast Cancer\|Stage IIA Breast Cancer\|Stage IIB Breast Cancer\|Stage III Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer
NCT04003038	Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery	https://clinicaltrials.gov/study/NCT04003038		RECRUITING	Body Mass Index Greater Than or Equal to 30\|Malignant Breast Neoplasm\|Mammoplasty Patient\|Obesity
NCT06399276	4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity	https://clinicaltrials.gov/study/NCT06399276		RECRUITING	Breast Cancer
NCT02681120	Pilot Study of the Effect of Weight Loss on Breast Tissue and Blood Biomarkers in Women at Increased Risk for Breast Cancer	https://clinicaltrials.gov/study/NCT02681120		COMPLETED	Breast Neoplasms\|Obesity
NCT03111680	Healthy Families to Change Obesity in Public Housing Residents	https://clinicaltrials.gov/study/NCT03111680		COMPLETED	Breast Cancer
NCT02028221	Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk	https://clinicaltrials.gov/study/NCT02028221		COMPLETED	Breast Cancer Prevention
NCT01472445	Vitamin D and Breast Cancer: Does Weight Make a Difference?	https://clinicaltrials.gov/study/NCT01472445		TERMINATED	Breast Cancer
NCT02538484	Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Subjects	https://clinicaltrials.gov/study/NCT02538484		COMPLETED	Breast Cancer
NCT04504201	Patient-centered Communication About Healthy Weight in Early Breast Cancer	https://clinicaltrials.gov/study/NCT04504201		COMPLETED	Breast Cancer
NCT01975363	Pilot Study of Curcumin for Women With Obesity and High Risk for Breast Cancer	https://clinicaltrials.gov/study/NCT01975363		COMPLETED	Atypical Ductal Breast Hyperplasia\|BRCA1 Gene Mutation\|BRCA2 Gene Mutation\|Ductal Breast Carcinoma in Situ\|Lobular Breast Carcinoma in Situ
NCT03575624	Changing Health Behaviors to Manage Chronic Conditions in Community-dwelling African American Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT03575624		COMPLETED	Breast Cancer Female\|Survivorship
NCT01127867	A Pilot Study of Docosahexaenoic Acid (DHA) in Obese Menopausal Women	https://clinicaltrials.gov/study/NCT01127867		COMPLETED	Breast Cancer\|Obesity
NCT02095184	GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese Patients	https://clinicaltrials.gov/study/NCT02095184		RECRUITING	Breast Cancer
NCT02062255	Impact of COX2 on Sera Biomarkers From Obese Subjects	https://clinicaltrials.gov/study/NCT02062255		COMPLETED	Breast Cancer Survivors
NCT00859989	A Weight-Loss Program in Helping Obese Black Women Lose Weight	https://clinicaltrials.gov/study/NCT00859989		UNKNOWN	Breast Cancer\|Obesity\|Weight Changes
NCT04117438	Tell us Your Food Story	https://clinicaltrials.gov/study/NCT04117438		WITHDRAWN	Breast Neoplasms
NCT01542203	Impact of Body Weight on Pharmacokinetic Analysis of Doxorubicin + Cyclophosphamide in Breast Cancer	https://clinicaltrials.gov/study/NCT01542203		WITHDRAWN	Breast Cancer
NCT05113485	UCLA Breast Cancer Survivor Health Promotion Research Study	https://clinicaltrials.gov/study/NCT05113485		UNKNOWN	Breast Cancer
NCT02432950	Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer	https://clinicaltrials.gov/study/NCT02432950		COMPLETED	Obesity\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage IIA Breast Cancer\|Stage IIB Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer
NCT01582685	Exercise in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01582685		WITHDRAWN	Breast Cancer\|Obesity
NCT06485089	Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers	https://clinicaltrials.gov/study/NCT06485089		NOT_YET_RECRUITING	Obesity\|Breast Cancer Risk
NCT01784042	Dietary Energy Restriction and Omega-3 Fatty Acids on Mammary Tissue	https://clinicaltrials.gov/study/NCT01784042		WITHDRAWN	Breast Cancer
NCT03029182	Simulated-altitude to Optimize Aerobic Exercise Among Breast Cancer Survivors With Limited Mobility	https://clinicaltrials.gov/study/NCT03029182		COMPLETED	Obesity\|Breast Cancer
NCT01793948	Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer	https://clinicaltrials.gov/study/NCT01793948		COMPLETED	Breast Cancer\|Obesity
NCT01837147	Using Technology to Improve Physical Activity Levels Among Postmenopausal Women (The Active & Aware Study)	https://clinicaltrials.gov/study/NCT01837147		COMPLETED	Breast Cancer
NCT01441011	Rural Women Connecting for Better Health	https://clinicaltrials.gov/study/NCT01441011		COMPLETED	Breast Cancer\|Obesity
NCT04291950	Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women	https://clinicaltrials.gov/study/NCT04291950		WITHDRAWN	Triple Negative Breast Cancer
NCT04298086	A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer	https://clinicaltrials.gov/study/NCT04298086		ACTIVE_NOT_RECRUITING	Breast Cancer\|Primary Hormone Receptor Positive Breast Cancer
NCT01504789	Part II: Exercise in Hispanic Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01504789		ACTIVE_NOT_RECRUITING	Breast Cancer
NCT00343434	Soy-Based Meal Replacement in Helping Women With Stage I, Stage II, or Stage III Breast Cancer in Complete Remission Lose Weight	https://clinicaltrials.gov/study/NCT00343434		COMPLETED	Breast Cancer\|Obesity
NCT01537029	Effect of Weight on the Population Pharmacokinetic Analysis of Doxorubicin and Cyclophosphamide	https://clinicaltrials.gov/study/NCT01537029		COMPLETED	Breast Cancer\|Obesity
NCT00131950	Effect of Lifestyle Factors and Hormone Function on Breast Density in Healthy Hispanic Women Who Are Undergoing Mammography for Breast Cancer Screening	https://clinicaltrials.gov/study/NCT00131950		COMPLETED	Breast Cancer
NCT00120029	Peer Counseling for Weight Loss	https://clinicaltrials.gov/study/NCT00120029		UNKNOWN	Breast Cancer
NCT01166672	BCRL Prevention Pilot	https://clinicaltrials.gov/study/NCT01166672		COMPLETED	Obesity\|Breast Cancer
NCT01627067	Exemestane-RAD001-Metformin	https://clinicaltrials.gov/study/NCT01627067		TERMINATED	Breast Cancer
NCT02574507	Behavioral Weight and Symptom Management for Breast Cancer Survivors and Partners	https://clinicaltrials.gov/study/NCT02574507		COMPLETED	Breast Cancer
NCT06106477	Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer	https://clinicaltrials.gov/study/NCT06106477		RECRUITING	Breast Cancer
NCT03712813	Effect of Low Intensity Vibration (LIV) on Aromatase Inhibitor- Induced Musculoskeletal Dysfunction in Early Stage Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT03712813		RECRUITING	Breast Cancer
NCT05265715	A Low AGE (Advanced Glycation End-product) Dietary Intervention for Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT05265715		COMPLETED	Breast Cancer
NCT02969291	A Home-Based Study to Enhance Activity in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT02969291		COMPLETED	Breast Cancer
NCT02279303	Rx for Better Breast Health	https://clinicaltrials.gov/study/NCT02279303		COMPLETED	Breast Cancer
NCT04129346	Technology-Supported Physical Activity Intervention for Metastatic Breast Cancer Survivors: Fit2ThriveMB	https://clinicaltrials.gov/study/NCT04129346		COMPLETED	Metastatic Breast Cancer\|Obesity
NCT04365569	Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program	https://clinicaltrials.gov/study/NCT04365569		RECRUITING	Breast Cancer
NCT04170335	Effects of Bariatric Surgery on Breast Density Improvement and Impact on Breast Cancer Risk in Severe Obese Patients	https://clinicaltrials.gov/study/NCT04170335		WITHDRAWN	Breast Cancer\|Morbid Obesity\|Bariatric Surgery Candidate
NCT03270111	High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women	https://clinicaltrials.gov/study/NCT03270111		COMPLETED	Breast Cancer Female
NCT02940470	Weight Loss Pilot Study in Postmenopausal Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT02940470		COMPLETED	Breast Cancer\|Obesity\|Overweight
NCT04717050	Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity	https://clinicaltrials.gov/study/NCT04717050		RECRUITING	Breast Cancer\|Coronary Artery Disease\|Stroke\|Type2 Diabetes
NCT00904033	Calcitriol, Physical Activity, and Bone Health in Cancer Survivors	https://clinicaltrials.gov/study/NCT00904033		COMPLETED	Breast Neoplasms\|Bone and Bones
NCT04330339	Prolonged Nightly Fasting in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04330339		COMPLETED	Fasting\|Breast Cancer\|Survivorship\|Breast Cancer Recurrent
NCT00470119	Effect of a Low-Calorie Diet and/or Exercise Program on Risk Factors for Developing Breast Cancer in Overweight or Obese Postmenopausal Women	https://clinicaltrials.gov/study/NCT00470119		COMPLETED	Breast Cancer\|Obesity\|Weight Changes
NCT06195306	Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction	https://clinicaltrials.gov/study/NCT06195306		NOT_YET_RECRUITING	Breast Atypical Hyperplasia\|Breast Carcinoma\|Breast Ductal Carcinoma In Situ\|Breast Lobular Carcinoma In Situ
NCT05386719	Cardiometabolic Screening Program	https://clinicaltrials.gov/study/NCT05386719		RECRUITING	Breast Cancer\|Early-stage Breast Cancer
NCT04321135	Avanzando Juntas: Adapting an Evidence Based Weight Loss Program for Hispanic Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04321135		COMPLETED	Breast Cancer\|Gynecologic Cancer
NCT04967209	Investigation of a Digital Healthy Habits Program for Individuals With Breast Cancer	https://clinicaltrials.gov/study/NCT04967209		COMPLETED	Cancer\|Breast Cancer\|Obesity\|Overweight and Obesity\|Overweight
NCT04554316	Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery	https://clinicaltrials.gov/study/NCT04554316		COMPLETED	Scar\|Breast Neoplasms\|Breast Diseases\|Surgical Wound
NCT00872677	Weight Loss Counseling for African American Women Who Are Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT00872677		COMPLETED	Breast Cancer\|Obesity\|Weight Changes
NCT02938780	Using Behavioral Economics to Achieve Improved Healthy Behavior Outcomes in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT02938780		COMPLETED	Breast Cancer Female
NCT02677857	Developing a Healthy Lifestyle in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT02677857		TERMINATED	Breast Cancer\|Sedentary Lifestyle
NCT03120390	Physical Activity in Reducing Metabolic Dysregulation (MetD) in Obese Latina Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT03120390		WITHDRAWN	Cancer Survivor\|Central Obesity\|No Evidence of Disease
NCT04741802	TOPS for African American Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04741802		COMPLETED	Feasibility and Acceptability of the TOPS Program\|Obesity\|Breast Cancer\|Weight Loss
NCT04210128	Glucose Monitoring to Predict and Treat High Glucose Levels After Steroid Treatment	https://clinicaltrials.gov/study/NCT04210128		COMPLETED	Breast Cancer\|Pancreatic Cancer\|Diabetes\|Pre Diabetes
NCT02871388	Addressing Modifiable Breast Cancer Risk Factors With Project CONECT	https://clinicaltrials.gov/study/NCT02871388		COMPLETED	Weight Loss\|Breast Cancer Risk Factors
NCT01157130	Breast Cancer Patients: A Breast Cancer Rehabilitation and Exercise Laboratory	https://clinicaltrials.gov/study/NCT01157130		UNKNOWN	Early Stage Breast Cancer (Stage 0-III)
NCT02370277	Effects of Chemotherapy on Intestinal Bacteria in Patients With Newly Diagnosed Breast Cancer	https://clinicaltrials.gov/study/NCT02370277		COMPLETED	Ductal Breast Carcinoma In Situ\|Invasive Breast Carcinoma\|Stage I Breast Cancer\|Stage IIA Breast Cancer\|Stage IIB Breast Cancer\|Stage IIIA Breast Cancer
NCT04454086	Exercise and Diet Counseling Program in Improving Quality of Life in Stage I-III Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04454086		COMPLETED	Anatomic Stage I Breast Cancer AJCC v8\|Anatomic Stage IA Breast Cancer AJCC v8\|Anatomic Stage IB Breast Cancer AJCC v8\|Anatomic Stage II Breast Cancer AJCC v8\|Anatomic Stage IIA Breast Cancer AJCC v8\|Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Cancer Survivor\|Obesity\|Overweight\|Prognostic Stage I Breast Cancer AJCC v8\|Prognostic Stage IA Breast Cancer AJCC v8\|Prognostic Stage IB Breast Cancer AJCC v8\|Prognostic Stage II Breast Cancer AJCC v8\|Prognostic Stage IIA Breast Cancer AJCC v8\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8
NCT01871116	POWER-remote Weight Loss Program in Early Stage Breast Cancer	https://clinicaltrials.gov/study/NCT01871116		COMPLETED	Early Stage Breast Cancer
NCT05930483	Remotely Delivered, Culturally Tailored Weight Loss Interventions Among Latina Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT05930483		NOT_YET_RECRUITING	Anatomic Stage I Breast Cancer AJCC v8\|Anatomic Stage II Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8
NCT02037542	A Study of Lifestyle Intervention in Overweight or Obese Women With Early Stage Breast Cancer	https://clinicaltrials.gov/study/NCT02037542		COMPLETED	Weight
NCT03546972	Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants	https://clinicaltrials.gov/study/NCT03546972		ACTIVE_NOT_RECRUITING	Deleterious BRCA1 Gene Mutation\|Deleterious BRCA2 Gene Mutation\|Ductal Breast Carcinoma In Situ\|Obesity\|Overweight\|Premalignant Lesion
NCT02923401	High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer	https://clinicaltrials.gov/study/NCT02923401		COMPLETED	Disorders of Breast
NCT00509626	Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy	https://clinicaltrials.gov/study/NCT00509626		COMPLETED	Breast Cancer\|Depression\|Fatigue\|Psychosocial Effects of Cancer and Its Treatment\|Weight Changes
NCT05012176	An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT05012176		ACTIVE_NOT_RECRUITING	Anatomic Stage 0 Breast Cancer AJCC v8\|Anatomic Stage I Breast Cancer AJCC v8\|Anatomic Stage IA Breast Cancer AJCC v8\|Anatomic Stage IB Breast Cancer AJCC v8\|Anatomic Stage II Breast Cancer AJCC v8\|Anatomic Stage IIA Breast Cancer AJCC v8\|Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Breast Ductal Carcinoma In Situ\|Invasive Breast Carcinoma\|Prognostic Stage 0 Breast Cancer AJCC v8\|Prognostic Stage I Breast Cancer AJCC v8\|Prognostic Stage IA Breast Cancer AJCC v8\|Prognostic Stage IB Breast Cancer AJCC v8\|Prognostic Stage II Breast Cancer AJCC v8\|Prognostic Stage IIA Breast Cancer AJCC v8\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8
NCT04799665	Dedicated Breast CT for Quantitative Breast Density Measurements in Mexican-origin Women in Southern Arizona	https://clinicaltrials.gov/study/NCT04799665		COMPLETED	Metabolic Syndrome\|Obesity Associated Disorder
NCT02103140	An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer	https://clinicaltrials.gov/study/NCT02103140		ACTIVE_NOT_RECRUITING	Metabolic Syndrome\|Obesity
NCT04753268	Mobile Behavior Change Program for Weight Loss in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04753268		COMPLETED	Weight Loss\|Behavior, Health
NCT03284346	Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors	https://clinicaltrials.gov/study/NCT03284346		TERMINATED	Cancer Survivor\|No Evidence of Disease\|Obesity\|Overweight\|Prostate Carcinoma\|Sedentary Lifestyle\|Stage I Breast Cancer\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage II Breast Cancer\|Stage IIA Breast Cancer\|Stage IIB Breast Cancer\|Stage III Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer
NCT05721976	With Love, Grandma ("Con Cariño, Abuelita") Pilot Study	https://clinicaltrials.gov/study/NCT05721976		RECRUITING	Cancer, Breast\|Cancer, Uterus\|Cancer, Ovary\|Obesity\|Activity, Motor\|Diet, Healthy
NCT06315296	An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer	https://clinicaltrials.gov/study/NCT06315296		RECRUITING	Anatomic Stage IV Breast Cancer AJCC v8\|Metastatic Breast Carcinoma\|Metastatic Lung Carcinoma\|Metastatic Malignant Neoplasm in the Brain\|Stage IV Lung Cancer AJCC v8
NCT04352530	Culturally Appropriate Nutrition Communication for Mexican American Women	https://clinicaltrials.gov/study/NCT04352530		COMPLETED	Lifestyle Risk Reduction\|Nutrition Poor\|Chronic Disease\|Obesity\|Cancer, Breast
NCT03751449	Exercise and Nutrition Education in Improving Physical Function and Quality of Life in Older Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT03751449		TERMINATED	Anatomic Stage I Breast Cancer AJCC v8\|Anatomic Stage IA Breast Cancer AJCC v8\|Anatomic Stage IB Breast Cancer AJCC v8\|Anatomic Stage II Breast Cancer AJCC v8\|Anatomic Stage IIA Breast Cancer AJCC v8\|Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Cancer Survivor\|Inactivity\|Obesity\|Overweight\|Prognostic Stage I Breast Cancer AJCC v8\|Prognostic Stage IA Breast Cancer AJCC v8\|Prognostic Stage IB Breast Cancer AJCC v8\|Prognostic Stage II Breast Cancer AJCC v8\|Prognostic Stage IIA Breast Cancer AJCC v8\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8
NCT06123286	Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms	https://clinicaltrials.gov/study/NCT06123286		NOT_YET_RECRUITING	Breast Cancer\|Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)\|Joint Pain
NCT00032201	Cell Lines From High-Risk Breast Tissue	https://clinicaltrials.gov/study/NCT00032201		COMPLETED	Healthy
NCT04063410	Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy	https://clinicaltrials.gov/study/NCT04063410		WITHDRAWN	Mammoplasty Patient
NCT04499950	Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study	https://clinicaltrials.gov/study/NCT04499950	A-NEW	ACTIVE_NOT_RECRUITING	Breast Cancer\|Overweight or Obesity
NCT03779867	Acute Exercise Intervention in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT03779867	ACE	ACTIVE_NOT_RECRUITING	Breast Carcinoma
NCT04534309	Behavioral Weight Loss Program for Cancer Survivors in Maryland	https://clinicaltrials.gov/study/NCT04534309	ASPIRE	COMPLETED	Breast Cancer\|Prostate Cancer\|Melanoma (Skin)\|Endometrial Cancer\|Gallbladder Cancer\|Rectal Cancer\|Kidney Cancer\|Bladder Cancer
NCT06171945	Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors	https://clinicaltrials.gov/study/NCT06171945	AYAConnect	RECRUITING	Cancer\|Physical Activity\|Cancer Survivorship\|Mental Health\|Obesity
NCT04576247	Combined Modality Exercise and Appetite in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04576247	CARE	TERMINATED	Breast Cancer Female\|Overweight and Obesity
NCT01315483	Diet Composition, Weight Control, and Breast Carcinogenesis	https://clinicaltrials.gov/study/NCT01315483	CHOICE	COMPLETED	Breast Cancer
NCT03542604	Cancer, Obesity/Overweight and Insomnia Study	https://clinicaltrials.gov/study/NCT03542604	COIN	COMPLETED	Breast Cancer\|Overweight and Obesity\|Insomnia
NCT05780814	The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer	https://clinicaltrials.gov/study/NCT05780814	COIN	RECRUITING	Breast Cancer\|Insomnia\|Weight Gain
NCT01793168	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	https://clinicaltrials.gov/study/NCT01793168	CoRDS	RECRUITING	Rare Disorders\|Undiagnosed Disorders\|Disorders of Unknown Prevalence\|Cornelia De Lange Syndrome\|Prenatal Benign Hypophosphatasia\|Perinatal Lethal Hypophosphatasia\|Odontohypophosphatasia\|Adult Hypophosphatasia\|Childhood-onset Hypophosphatasia\|Infantile Hypophosphatasia\|Hypophosphatasia\|Kabuki Syndrome\|Bohring-Opitz Syndrome\|Narcolepsy Without Cataplexy\|Narcolepsy-cataplexy\|Hypersomnolence Disorder\|Idiopathic Hypersomnia Without Long Sleep Time\|Idiopathic Hypersomnia With Long Sleep Time\|Idiopathic Hypersomnia\|Kleine-Levin Syndrome\|Kawasaki Disease\|Leiomyosarcoma\|Leiomyosarcoma of the Corpus Uteri\|Leiomyosarcoma of the Cervix Uteri\|Leiomyosarcoma of Small Intestine\|Acquired Myasthenia Gravis\|Addison Disease\|Hyperacusis (Hyperacousis)\|Juvenile Myasthenia Gravis\|Transient Neonatal Myasthenia Gravis\|Williams Syndrome\|Lyme Disease\|Myasthenia Gravis\|Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome)\|Isolated Klippel-Feil Syndrome\|Frasier Syndrome\|Denys-Drash Syndrome\|Beckwith-Wiedemann Syndrome\|Emanuel Syndrome\|Isolated Aniridia\|Axenfeld-Rieger Syndrome\|Aniridia-intellectual Disability Syndrome\|Aniridia - Renal Agenesis - Psychomotor Retardation\|Aniridia - Ptosis - Intellectual Disability - Familial Obesity\|Aniridia - Cerebellar Ataxia - Intellectual Disability\|Aniridia - Absent Patella\|Aniridia\|Peters Anomaly - Cataract\|Peters Anomaly\|Potocki-Shaffer Syndrome\|Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11\|Silver-Russell Syndrome Due to Imprinting Defect of 11p15\|Silver-Russell Syndrome Due to 11p15 Microduplication\|Syndromic Aniridia\|WAGR Syndrome\|Wolf-Hirschhorn Syndrome\|4p16.3 Microduplication Syndrome\|4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome\|Autosomal Recessive Stickler Syndrome\|Stickler Syndrome Type 2\|Stickler Syndrome Type 1\|Stickler Syndrome\|Mucolipidosis Type 4\|X-linked Spinocerebellar Ataxia Type 4\|X-linked Spinocerebellar Ataxia Type 3\|X-linked Intellectual Disability - Ataxia - Apraxia\|X-linked Progressive Cerebellar Ataxia\|X-linked Non Progressive Cerebellar Ataxia\|X-linked Cerebellar Ataxia\|Vitamin B12 Deficiency Ataxia\|Toxic Exposure Ataxia\|Unclassified Autosomal Dominant Spinocerebellar Ataxia\|Thyroid Antibody Ataxia\|Sporadic Adult-onset Ataxia of Unknown Etiology\|Spinocerebellar Ataxia With Oculomotor Anomaly\|Spinocerebellar Ataxia With Epilepsy\|Spinocerebellar Ataxia With Axonal Neuropathy Type 2\|Spinocerebellar Ataxia Type 8\|Spinocerebellar Ataxia Type 7\|Spinocerebellar Ataxia Type 6\|Spinocerebellar Ataxia Type 5\|Spinocerebellar Ataxia Type 4\|Spinocerebellar Ataxia Type 37\|Spinocerebellar Ataxia Type 36\|Spinocerebellar Ataxia Type 35\|Spinocerebellar Ataxia Type 34\|Spinocerebellar Ataxia Type 32\|Spinocerebellar Ataxia Type 31\|Spinocerebellar Ataxia Type 30\|Spinocerebellar Ataxia Type 3\|Spinocerebellar Ataxia Type 29\|Spinocerebellar Ataxia Type 28\|Spinocerebellar Ataxia Type 27\|Spinocerebellar Ataxia Type 26\|Spinocerebellar Ataxia Type 25\|Spinocerebellar Ataxia Type 23\|Spinocerebellar Ataxia Type 22\|Spinocerebellar Ataxia Type 21\|Spinocerebellar Ataxia Type 20\|Spinocerebellar Ataxia Type 2\|Spinocerebellar Ataxia Type 19/22\|Spinocerebellar Ataxia Type 18\|Spinocerebellar Ataxia Type 17\|Spinocerebellar Ataxia Type 16\|Spinocerebellar Ataxia Type 15/16\|Spinocerebellar Ataxia Type 14\|Spinocerebellar Ataxia Type 13\|Spinocerebellar Ataxia Type 12\|Spinocerebellar Ataxia Type 11\|Spinocerebellar Ataxia Type 10\|Spinocerebellar Ataxia Type 1 With Axonal Neuropathy\|Spinocerebellar Ataxia Type 1\|Spinocerebellar Ataxia - Unknown\|Spinocerebellar Ataxia - Dysmorphism\|Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature\|Spasticity-ataxia-gait Anomalies Syndrome\|Spastic Ataxia With Congenital Miosis\|Spastic Ataxia - Corneal Dystrophy\|Spastic Ataxia\|Rare Hereditary Ataxia\|Rare Ataxia\|Recessive Mitochondrial Ataxia Syndrome\|Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature\|Posterior Column Ataxia - Retinitis Pigmentosa\|Post-Stroke Ataxia\|Post-Head Injury Ataxia\|Post Vaccination Ataxia\|Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract\|Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus\|Non-hereditary Degenerative Ataxia\|Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity\|Olivopontocerebellar Atrophy - Deafness\|NARP Syndrome\|Myoclonus - Cerebellar Ataxia - Deafness\|Multiple System Atrophy, Parkinsonian Type\|Multiple System Atrophy, Cerebellar Type\|Multiple System Atrophy\|Maternally-inherited Leigh Syndrome\|Machado-Joseph Disease Type 3\|Machado-Joseph Disease Type 2\|Machado-Joseph Disease Type 1\|Leigh Syndrome\|Late-onset Ataxia With Dementia\|Infection or Post Infection Ataxia\|GAD Ataxia\|Hereditary Episodic Ataxia\|Gliadin/Gluten Ataxia\|Friedreich Ataxia\|Fragile X-associated Tremor/Ataxia Syndrome\|Familial Paroxysmal Ataxia\|Exposure to Medications Ataxia\|Episodic Ataxia With Slurred Speech\|Episodic Ataxia Unknown Type\|Episodic Ataxia Type 7\|Episodic Ataxia Type 6\|Episodic Ataxia Type 5\|Episodic Ataxia Type 4\|Episodic Ataxia Type 3\|Episodic Ataxia Type 1\|Epilepsy and/or Ataxia With Myoclonus as Major Feature\|Early-onset Spastic Ataxia-neuropathy Syndrome\|Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity\|Early-onset Cerebellar Ataxia With Retained Tendon Reflexes\|Early-onset Ataxia With Dementia\|Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia\|Dilated Cardiomyopathy With Ataxia\|Cataract - Ataxia - Deafness\|Cerebellar Ataxia, Cayman Type\|Cerebellar Ataxia With Peripheral Neuropathy\|Cerebellar Ataxia - Hypogonadism\|Cerebellar Ataxia - Ectodermal Dysplasia\|Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss\|Brain Tumor Ataxia\|Brachydactyly - Nystagmus - Cerebellar Ataxia\|Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia\|Autosomal Recessive Syndromic Cerebellar Ataxia\|Autosomal Recessive Spastic Ataxia With Leukoencephalopathy\|Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay\|Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria\|Autosomal Recessive Spastic Ataxia\|Autosomal Recessive Metabolic Cerebellar Ataxia\|Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine\|Autosomal Recessive Ataxia, Beauce Type\|Autosomal Recessive Ataxia Due to Ubiquinone Deficiency\|Autosomal Recessive Ataxia Due to PEX10 Deficiency\|Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia\|Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency\|Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency\|Autosomal Recessive Congenital Cerebellar Ataxia\|Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency\|Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome\|Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity\|Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency\|Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect\|Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion\|Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation\|Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness\|Autosomal Recessive Cerebellar Ataxia\|Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly\|Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation\|Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy\|Autosomal Dominant Spastic Ataxia Type 1\|Autosomal Dominant Spastic Ataxia\|Autosomal Dominant Optic Atrophy\|Ataxia-telangiectasia Variant\|Ataxia-telangiectasia\|Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy\|Autosomal Dominant Cerebellar Ataxia Type 4\|Autosomal Dominant Cerebellar Ataxia Type 3\|Autosomal Dominant Cerebellar Ataxia Type 2\|Autosomal Dominant Cerebellar Ataxia Type 1\|Autosomal Dominant Cerebellar Ataxia\|Ataxia-telangiectasia-like Disorder\|Ataxia With Vitamin E Deficiency\|Ataxia With Dementia\|Ataxia - Oculomotor Apraxia Type 1\|Ataxia - Other\|Ataxia - Genetic Diagnosis - Unknown\|Acquired Ataxia\|Adult-onset Autosomal Recessive Cerebellar Ataxia\|Alcohol Related Ataxia\|Multiple Endocrine Neoplasia\|Multiple Endocrine Neoplasia Type II\|Multiple Endocrine Neoplasia Type 1\|Multiple Endocrine Neoplasia Type 2\|Multiple Endocrine Neoplasia, Type IV\|Multiple Endocrine Neoplasia, Type 3\|Multiple Endocrine Neoplasia (MEN) Syndrome\|Multiple Endocrine Neoplasia Type 2B\|Multiple Endocrine Neoplasia Type 2A\|Atypical Hemolytic Uremic Syndrome\|Atypical HUS\|Wiedemann-Steiner Syndrome\|Breast Implant-Associated Anaplastic Large Cell Lymphoma\|Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)\|Hemophagocytic Lymphohistiocytosis\|Behcet's Disease\|Alagille Syndrome\|Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD)\|Lowe Syndrome\|Pitt Hopkins Syndrome\|1p36 Deletion Syndrome\|Jansen Type Metaphyseal Chondrodysplasia\|Cockayne Syndrome\|Chronic Recurrent Multifocal Osteomyelitis\|CRMO\|Malan Syndrome\|Hereditary Sensory and Autonomic Neuropathy Type Ie\|VCP Disease\|Hypnic Jerking\|Sleep Myoclonus\|Mollaret Meningitis\|Recurrent Viral Meningitis\|CRB1\|Leber Congenital Amaurosis\|Retinitis Pigmentosa\|Rare Retinal Disorder\|KCNMA1-Channelopathy\|Primary Biliary Cirrhosis\|ZMYND11\|Transient Global Amnesia\|Glycogen Storage Disease\|Alstrom Syndrome\|White Sutton Syndrome\|DNM1\|EIEE31\|Myhre Syndrome\|Recurrent Respiratory Papillomatosis\|Laryngeal Papillomatosis\|Tracheal Papillomatosis\|Refsum Disease\|Nicolaides Baraitser Syndrome\|Leukodystrophy\|Tango2\|Cauda Equina Syndrome\|Rare Gastrointestinal Disorders\|Achalasia-Addisonian Syndrome\|Achalasia Cardia\|Achalasia Icrocephaly Syndrome\|Anal Fistula\|Congenital Sucrase-Isomaltase Deficiency\|Eosinophilic Gastroenteritis\|Idiopathic Gastroparesis\|Hirschsprung Disease\|Rare Inflammatory Bowel Disease\|Intestinal Pseudo-Obstruction\|Scleroderma\|Short Bowel Syndrome\|Sacral Agenesis\|Sacral Agenesis Syndrome\|Caudal Regression\|Scheuermann Disease\|SMC1A Truncated Mutations (Causing Loss of Gene Function)\|Cystinosis\|Juvenile Nephropathic Cystinosis\|Nephropathic Cystinosis\|Kennedy Disease\|Spinal Bulbar Muscular Atrophy\|Warburg Micro Syndrome\|Mucolipidoses\|Mitochondrial Diseases\|Mitochondrial Aminoacyl-tRNA Synthetases\|Mt-aaRS Disorders\|Hypertrophic Olivary Degeneration\|Non-Ketotic Hyperglycinemia\|Fish Odor Syndrome\|Halitosis\|Isolated Congenital Asplenia\|Lambert Eaton (LEMS)\|Biliary Atresia\|STAG1 Gene Mutation\|Coffin Lowry Syndrome\|Borjeson-Forssman-Lehman Syndrome\|Blau Syndrome\|Arginase 1 Deficiency\|HSPB8 Myopathy\|Beta-Mannosidosis\|TBX4 Syndrome\|DHDDS Gene Mutations\|MAND-MBD5-Associated Neurodevelopmental Disorder\|Constitutional Mismatch Repair Deficiency (CMMRD)\|SPATA5 Disorder\|SPATA5L1 Related Disorder
NCT01096901	Choose to Lose for Women-Weight Loss to Reduce Breast Cancer Risk Factors	https://clinicaltrials.gov/study/NCT01096901	CTL	COMPLETED	Obesity\|Overweight
NCT02224807	Effects of Diet and Exercise on Ductal Carcinoma in Situ	https://clinicaltrials.gov/study/NCT02224807	DCIS	COMPLETED	Ductal Carcinoma In Situ\|Breast Cancer
NCT04300478	Appetite and Exercise in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04300478	EARNESt	COMPLETED	Overweight\|Breast Cancer\|Obesity
NCT03824145	Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer	https://clinicaltrials.gov/study/NCT03824145	EDC	RECRUITING	Metastatic Breast Cancer
NCT01112839	Reducing Breast Cancer Recurrence With Weight Loss	https://clinicaltrials.gov/study/NCT01112839	ENERGY	COMPLETED	Breast Cancer\|Overweight\|Obesity
NCT01498536	Effect of Diet and Exercise in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01498536	F4F tri neg	COMPLETED	Breast Cancer\|Obesity
NCT06504914	Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT06504914	FIM-BCS	RECRUITING	Hypertension\|Obesity\|Nutrition, Healthy
NCT06518837	Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer	https://clinicaltrials.gov/study/NCT06518837	FITWISE	NOT_YET_RECRUITING	Hormone Receptor-Positive Breast Cancer\|HER2-Negative Breast Cancer
NCT05193149	Inspiratory Muscle Training in Obese Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT05193149	IMOCS	RECRUITING	Cancer Survivors\|Obesity\|Breast Cancer
NCT06318507	The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy	https://clinicaltrials.gov/study/NCT06318507	IMPACT	RECRUITING	Breast Neoplasms
NCT01728506	An Internet-based Weight Loss and Exercise Intervention for Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01728506	iWEB	UNKNOWN	Breast Cancer
NCT01559194	Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk	https://clinicaltrials.gov/study/NCT01559194	LEAF	COMPLETED	Breast Cancer\|Weight Loss
NCT02681965	A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT02681965	LEAN3	COMPLETED	Breast Cancer Survivorship\|Obesity
NCT02255240	LEVEL UP: Video Games for Activity in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT02255240	LEVEL UP	WITHDRAWN	Breast Cancer\|Obesity
NCT01896050	Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer	https://clinicaltrials.gov/study/NCT01896050	LOGRIBMET	COMPLETED	Breast Cancer\|Arthralgia\|Obesity
NCT01630499	My Lifestyle Intervention of Food and Exercise	https://clinicaltrials.gov/study/NCT01630499	MyLIFE	COMPLETED	Breast Cancer
NCT02273206	Collaborative Care to Reduce Depression and Increase Cancer Screening Among Low-Income Urban Women	https://clinicaltrials.gov/study/NCT02273206	PCM3	COMPLETED	Depression\|Breast Cancer Screening\|Cervical Cancer Screening\|Colorectal Cancer Screening
NCT00782366	Predictive Genetic Risk Assessment Trial	https://clinicaltrials.gov/study/NCT00782366	PGT	COMPLETED	Colon Cancer\|Lung Cancer\|Atrial Fibrillation\|Diabetes Type 2\|Obesity\|Breast Cancer\|Graves Disease\|Osteoarthritis\|Celiac Disease\|Myocardial Infarction\|Prostate Cancer
NCT02152462	Exergaming Intervention and Breast Cancer Biomarkers in Black Women	https://clinicaltrials.gov/study/NCT02152462	POWER	COMPLETED	Breast Cancer\|Obesity
NCT05048108	Remote Assessment of Cognition, Insulin Resistance and Omega-3 Fatty Acid Biomarkers in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT05048108	RACIRO-3	ACTIVE_NOT_RECRUITING	Breast Cancer\|Obesity
NCT05848856	The RISC Registry--Risk Informed Screening Registry	https://clinicaltrials.gov/study/NCT05848856	RISC	NOT_YET_RECRUITING	Breast Cancer Risk\|Cardiovascular Disease Risk\|Cardiometabolic Risk\|Diabetes
NCT04326660	SCOPE-Chinese Women Study	https://clinicaltrials.gov/study/NCT04326660	SCOPE	COMPLETED	Cancer, Breast\|Obesity, Abdominal
NCT00774371	Weight Reduction Intervention for Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT00774371	SHAPE	COMPLETED	Breast Cancer
NCT02341235	Self-monitoring Activity: a Randomized Trial of Game-oriented Applications	https://clinicaltrials.gov/study/NCT02341235	SMARTGOAL	COMPLETED	Breast Cancer\|Obesity
NCT02431676	Survivorship Promotion In Reducing IGF-1 Trial	https://clinicaltrials.gov/study/NCT02431676	SPIRIT	COMPLETED	Breast Cancer\|Prostate Cancer\|Lung Cancer\|Colon Cancer\|Melanoma of Skin\|Endometrial Cancer\|Liver Cancer\|Pancreatic Cancer\|Rectal Cancer\|Kidney Cancer\|Other Solid Malignant Tumors
NCT04965246	Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04965246	TALIEHO	RECRUITING	Inflammation\|Cognitive Impairment\|Anxiety\|Alcohol Drinking
NCT04855552	Telehealth Weight Loss Program for Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT04855552	TWL	ACTIVE_NOT_RECRUITING	Cancer Survivors\|Cancer of Breast\|Body Weight\|Overweight and Obesity
NCT01482702	Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01482702	VCC0910	COMPLETED	Overweight\|Postmenopausal\|Breast Cancer
NCT01240213	Vitamin D, Diet and Activity Study	https://clinicaltrials.gov/study/NCT01240213	ViDA	COMPLETED	Breast Cancer\|Obesity\|Hypovitaminosis D
NCT00393172	Women in Steady Exercise Research [Formerly Women, Oxidative Stress, Exercise and Estrogens (WOSEE)]	https://clinicaltrials.gov/study/NCT00393172	WISER	COMPLETED	Breast Cancer\|Obesity
NCT01515124	The Women In Steady Exercise Research (WISER) Survivor Trial	https://clinicaltrials.gov/study/NCT01515124	WISER Survivor	COMPLETED	Lymphedema
NCT00476203	Yoga Study in Breast Cancer Patients	https://clinicaltrials.gov/study/NCT00476203	Yoga	COMPLETED	Breast Cancer

New and existing studies added or modified at clinicaltrials.gov

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Recent Breast Cancer News

Breast Cancer Reviews

To see all 186 Reviews, go directly to PubMed.

REVIEWS from PubMed – July 5, 2024 – Obesity AND Cancer AND Breast AND Review

Association between metabolic and bariatric surgery and malignancy: a systematic review, meta-analysis, trends, and conclusions November 24, 2024
CONCLUSIONS: According to the data retrieved from patients who underwent MBS compared to nonoperated patients suffering from obesity, the overall risk for malignancy was lower in the MBS group. Additional information collected in this study revealed the behavior of specific types of cancer in response to induced weight loss by operative means. The benefit of […]
Libi-Or Madar
Long-Term Randomized Controlled Trials of Diet Intervention Reports and Their Impact on Cancer: A Systematic Review October 16, 2024
CONCLUSIONS: More long-term RCTs evaluating cancer and cancer-related biomarker endpoints are needed, especially for cancers at sites other than the breast.
Edward R Sauter
Association of metabolic obesity phenotypes with risk of overall and site-specific cancers: a systematic review and meta-analysis of cohort studies September 24, 2024
CONCLUSION: These findings suggest that both higher adiposity and metabolic dysfunction were independently associated with increased risk of several cancers, with the strongest associations generally observed among those with both metabolic dysfunction and obesity.
Yahya Mahamat-Saleh
An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals August 26, 2024
Background: Epidemiological research investigating the impact of exposure to plastics, and plastic-associated chemicals, on human health is critical, especially given exponentially increasing plastic production. In parallel with increasing production, academic research has also increased exponentially both in terms of the primary literature and ensuing systematic reviews with meta-analysis. However, there are few overviews that capture […]
Christos Symeonides
The effects of green exercise on the mental and physical health of people with chronic conditions: a systematic review August 21, 2024
Green exercise, defined as physical activity in natural settings, shows promise for enhancing exercise participation and improving health. This systematic review aimed to assess the effectiveness of green exercise in people with chronic conditions. Seven electronic databases were searched and of the 7801 screened articles, 14 trials met the inclusion criteria. Green exercise was a […]
Aristi Tsokani
The effect of BMI on survival outcome of breast cancer patients: a systematic review and meta-analysis July 16, 2024
CONCLUSIONS: The results of our meta-analysis reveal a notable association between BMI and various survival measures in breast cancer prognosis. These findings provide a solid basis for predicting breast cancer outcomes and implementing more effective therapeutic approaches.
Yu-Huan Kong
Comorbid physical health outcomes in patients with bipolar disorder: An umbrella review of systematic reviews and meta-analyses July 11, 2024
CONCLUSION: Individuals with BD are predisposed to numerous comorbid physical conditions, though these links are supported by various evidence levels and necessitate further studies. It is imperative that physicians be aware of these potential comorbidities in patients with BD and take proactive measures to manage them.
Jiseung Kang
Prognostic Factors Associated with Breast Cancer-Specific Survival from 1995 to 2022: A Systematic Review and Meta-Analysis of 1,386,663 Cases from 30 Countries June 26, 2024
Breast cancer is the fifth-ranked cancer globally. Despite early diagnosis and advances in treatment, breast cancer mortality is increasing. This meta-analysis aims to examine all possible prognostic factors that improve/deteriorate breast cancer-specific survival. MEDLINE, PubMed, ScienceDirect, Ovid, and Google Scholar were systematically searched until September 16, 2023. The retrieved studies from 1995 to 2022 accumulated […]
Hanif Abdul Rahman
A Systematic Review on Prevalence of Overweight and Obesity among School Children and Adolescents in Indian Population June 24, 2024
Obesity has erupted as an epidemic around the world. It has set itself as a fast wave among other prevailing specific clusters of non-communicable diseases. The current study reviews and presents an updated meaningful review of the vast research work performed at schools located in different cities of India. A systematic search was conducted in […]
Nidhi Sharma
Combined Aerobic and Resistance Training Improves Body Composition, Alters Cardiometabolic Risk, and Ameliorates Cancer-Related Indicators in Breast Cancer Patients and Survivors with Overweight/Obesity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials June 6, 2024
Breast cancer survivors with obesity are at a high risk of cancer recurrence, comorbidity, and mortality. This review aims to systematically evaluate the effects of combined aerobic and resistance training (CART) on body composition, lipid homeostasis, inflammation, adipokines, cancer-related fatigue, sleep, and quality of life in breast cancer patients and survivors with overweight/obesity. An electronic […]
Sameer Badri Al-Mhanna
Reporting on patient's body mass index (BMI) in recent clinical trials for patients with breast cancer: a systematic review May 22, 2024
CONCLUSIONS: Patient adiposity is hardly considered as most novel drug treatments are given in a fixed dose. BMI is generally not reported in recent trials and few secondary analyses are performed. Given the prevalence of patients with obesity and the impact obesity can have on pharmacokinetics and cancer biology, more attention should be given by […]
Josephine Van Cauwenberge
Co-design of an intervention to optimize mammographic screening participation in women with obesity and/or physical disabilities April 24, 2024
CONCLUSION: Development and evaluation of interventions informed by frameworks like the one developed in this study are needed to improve engagement in screening to promote regular participation among women with physical disabilities and/or obesity.
K A McBride
Breast cancer risk prediction using machine learning: a systematic review April 4, 2024
CONCLUSION: This study offers investigators a different perspective on the use of AI for breast cancer risk prediction, incorporating numerous imaging and non-imaging features.
Sadam Hussain
Lifestyle interventions with dietary strategies after breast cancer diagnosis: a systematic review March 29, 2024
CONCLUSION: This review demonstrated promising evidence for the efficacy of lifestyle interventions with dietary strategies in breast cancer survivors. However, culturally tailored interventions and interventions conducted before and during treatment are lacking.
Acadia W Buro
Role of body mass index and weight change in the risk of cancer: A systematic review and meta-analysis of 66 cohort studies March 28, 2024
CONCLUSIONS: Overweight and obesity increase the risk of most cancers, and weight loss of >5 kg reduces overall cancer risk. These findings provide insights for cancer prevention and help to elucidate the mechanisms underlying cancer development.
Xiaoye Shi

Obesity Breast Cancer Papers

To see all >777 Papers, go directly to PubMed.

RECENT PAPERS from PubMed – July 5, 2024 – Obesity (in title) AND Cancer (in title) AND Breast (in title)

Normal weight obesity, circulating biomarkers and risk of breast cancer: a prospective cohort study and meta-analysis November 28, 2024
CONCLUSIONS: NWO is associated with an increased risk of postmenopausal breast cancer, indicating that relying solely on BMI neglects the higher risk faced by non-obese postmenopausal women.
Wenjie Wang
The Epigenetic Landscape of Breast Cancer, Metabolism, and Obesity November 25, 2024
Obesity is a risk factor for developing breast cancer, and significantly increases mortality rates in patients diagnosed with this disease. Drivers of this unfortunate relationships are multifactorial, with obesity-induced changes in the epigenetic state of breast cancer cells being identified as a critical mechanism that impact survival, metastasis, and therapeutic responses. Recent studies have investigated […]
Ashley Townsel
Study: BMI May Underestimate Obesity-Linked Breast Cancer Risk November 15, 2024
No abstract
Samantha Anderer
Obesity and lack of breastfeeding: a perfect storm to augment risk of breast cancer? November 11, 2024
Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer with higher rates of recurrence and distant metastasis, as well as decreased 5-year survival rates. Racial disparities are evident in the incidence and mortality rates of triple negative breast cancer particularly increased in young African American women. Concurrently, young African American […]
Kate Ormiston
Significance of LIF/LIFR Signaling in the Progression of Obesity-Driven Triple-Negative Breast Cancer November 9, 2024
American women with obesity have an increased incidence of triple-negative breast cancer (TNBC). The impact of obesity conditions on the tumor microenvironment is suspected to accelerate TNBC progression; however, the specific mechanism(s) remains elusive. This study explores the hypothesis that obesity upregulates leukemia inhibitory factor receptor (LIFR) oncogenic signaling in TNBC and assesses the efficacy […]
Lois Randolph
Impact of obesity on pathological complete remission in early stage breast cancer patients after neoadjuvant chemotherapy: a retrospective study from a German University breast center October 28, 2024
CONCLUSION: In this retrospective study, obesity significantly affected the likelihood of achieving pCR in patients with eBC cancer undergoing NACT after adjusting for covariates. While obesity is a known risk factor for breast cancer development and progression, its impact on the efficacy of NACT in terms of achieving pCR was positive in our study. These […]
Johannes Felix Englisch
Influence of Obesity and Sociodemographic Features on the Physical Fitness of Breast Cancer Survivors October 25, 2024
CONCLUSIONS: In the studied group of breast cancer survivors, there is a high prevalence of overweight and obesity. With increasing obesity rates, older age, and lower education levels, physical activity measured by the SFT decreases. Living in urban areas and being professionally active also predispose to lower physical activity levels. As obesity indices increase, physical […]
Malgorzata Biskup
Obesity and leptin in breast cancer angiogenesis October 23, 2024
At the time of breast cancer diagnosis, most patients meet the diagnostic criteria to be classified as obese or overweight. This can significantly impact patient outcome: breast cancer patients with obesity (body mass index > 30) have a poorer prognosis compared to patients with a lean BMI. Obesity is associated with hyperleptinemia, and leptin is […]
Courtney B Lagarde
Adipocyte-derived glutathione promotes obesity-related breast cancer by regulating the SCARB2-ARF1-mTORC1 complex October 23, 2024
Obesity is a major risk factor for poor breast cancer outcomes, but the impact of obesity-induced tumor microenvironment (TME) metabolites on breast cancer growth and metastasis remains unclear. Here, we performed TME metabolomic analysis in high-fat diet (HFD) mouse models and found that glutathione (GSH) levels were elevated in the TME of obesity-accelerated breast cancer. […]
Chenxi Zhao
Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer October 17, 2024
Breast cancer, the most common cancer among women worldwide, continues to pose significant public health challenges. Among the subtypes of breast cancer, triple-negative breast cancer (TNBC) is particularly aggressive and difficult to treat due to the absence of receptors for estrogen, progesterone, or human epidermal growth factor receptor 2, rendering TNBC refractory to conventional targeted […]
Pablo Llevenes
Single-cell RNA-sequencing reveals a unique landscape of the tumor microenvironment in obesity-associated breast cancer September 19, 2024
As two diseases with rapidly increasing incidence, the molecular linkages between obesity and breast cancer (BC) are intriguing. Overall, obesity may be a negative prognostic factor for BC. Single-cell RNA-sequencing (scRNA-seq) was performed on tumor tissues from 6 obese and non-obese BC patients. With 48,033 cells analyzed, we found heterogeneous tumor epithelium and microenvironment in […]
Guanghui Zhao
Obesity-Associated Breast Cancer: Analysis of Risk Factors and Current Clinical Evaluation September 17, 2024
Several studies show that a significantly stronger association is obvious between increased body mass index (BMI) and higher breast cancer incidence. Additionally, obese and postmenopausal women are at higher risk of all-cause and breast cancer-specific mortality compared with non-obese women with breast cancer. In this context, increased levels of estrogens, excessive aromatization activity of the […]
Atilla Engin
Obesity-Senescence-Breast Cancer: Clinical Presentation of a Common Unfortunate Cycle September 17, 2024
There are few convincing studies establishing the relationship between endogenous factors that cause obesity, cellular aging, and telomere shortening. Without a functional telomerase, a cell undergoing cell division has progressive telomere shortening. While obesity influences health and longevity as well as telomere dynamics, cellular senescence is one of the major drivers of the aging process […]
Ayse Basak Engin
Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer September 9, 2024
Breast cancer is the most common cancer in women, and incidence rates are rising, it is thought in part, due to increasing levels of obesity. Endocrine therapy (ET) remains the cornerstone of systemic therapy for early and advanced oestrogen receptor-positive (ER + ) breast cancer, but despite treatment advances, it is becoming more evident that […]
Sohail Rooman Javed
Impact of Obesity on Breast Cancer Clinicopathological Characteristics in Underserved US Community Safety-Net Hospital: A Retrospective Single-Center Study September 5, 2024
CONCLUSION: This observational retrospective hypothesis-generating study revealed the association between obesity and disease stage and menopause status at diagnosis. In postmenopausal patients, obesity correlated with larger tumor size and advanced lymph node disease involvement. Additionally, ethnic variations were observed, with a higher prevalence of obesity among African American patients.
Ekaterina Proskuriakova
Comparing long-term prognosis following different surgical methods in patients with early stage breast cancer and obesity: a retrospective cohort study in China August 30, 2024
CONCLUSION: In patients with early stage breast cancer and obesity, TM is associated with better survival outcomes than BCT.
Lun Li
Development and Characterization of Syngeneic Orthotopic Transplant Models of Obesity-Responsive Triple-Negative Breast Cancer in C57BL/6J Mice August 29, 2024
Obesity is an established risk and progression factor for triple-negative breast cancer (TNBC), but preclinical studies to delineate the mechanisms underlying the obesity-TNBC link as well as strategies to break that link are constrained by the lack of tumor models syngeneic to obesity-prone mouse strains. C3(1)/SV40 T-antigen (C3-TAg) transgenic mice on an FVB genetic background […]
Meredith S Carson
Phase angle as a potential tool to evaluate chronic inflammatory state and predict quality of life deterioration in women with breast cancer and obesity: A narrative review August 16, 2024
The interaction between lifestyle--defined more specifically in health care as the personal exposome--and its implications on obesity and breast cancer development highlights the critical role of body composition and inflammation in these patients. There is clear evidence that the personal and internal exposome triggers biochemical, inflammatory, and metabolic reprogramming, which might favor ectopic lipid accumulation […]
Fernanda Sarahí Fajardo-Espinoza
The intricate relationship between obesity, type 2 diabetes and female breast cancer: A retrospective study of 335 women August 12, 2024
CONCLUSIONS: These results confirm excess body weight and T2D as unfavorable prognostic factors in terms of the presence of the TNBC subtype, tumor metastasis, recurrence, and aggressiveness (G3 and Ki-67 > 20%). This study highlights the importance of prevention in all women, with early screening, and adequate nutritional programs.
Ilaria Milani
Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program July 29, 2024
CONCLUSIONS AND RELEVANCE: In this cohort study of patients with BC, obesity and high serum leptin levels were associated with an enhanced risk of early-onset BC and diagnosis of luminal A and TNBC subtypes in Black women. These findings should help in developing strategies to narrow the existing disparity gaps.
Sarabjeet Kour Sudan

US Clinical Trials involving Breast Cancer and Obesity

(update March 24, 2024)

NCT Number	Study Title	Study URL	Acronym	Study Status	Interventions	Sponsor	Collaborators	Enrollment	Study Type
NCT01302379	Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT01302379		COMPLETED	DRUG: Metformin\|DRUG: Placebo\|BEHAVIORAL: Lifestyle intervention\|BEHAVIORAL: Standard printed dietary guidelines	University of California, San Diego		333	INTERVENTIONAL
NCT00933309	The Impact of Obesity and Obesity Treatments on Breast Cancer	https://clinicaltrials.gov/study/NCT00933309		COMPLETED	DRUG: Exemestane\|DRUG: Avandamet	M.D. Anderson Cancer Center	Susan G. Komen Breast Cancer Foundation	25	INTERVENTIONAL
NCT04720209	Taking AIM at Breast Cancer	https://clinicaltrials.gov/study/NCT04720209		RECRUITING	OTHER: CARE\|OTHER: TARE\|OTHER: Home-Based Stretching	Dana-Farber Cancer Institute	National Cancer Institute (NCI)	300	INTERVENTIONAL
NCT04913064	Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer	https://clinicaltrials.gov/study/NCT04913064		RECRUITING	OTHER: Questionnaire Administration\|DRUG: White Button Mushroom Extract	City of Hope Medical Center	National Cancer Institute (NCI)	26	INTERVENTIONAL
NCT06318507	The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy	https://clinicaltrials.gov/study/NCT06318507	IMPACT	RECRUITING	COMBINATION_PRODUCT: Fecal microbial diversity	Pennington Biomedical Research Center		25	OBSERVATIONAL
NCT02750826	Breast Cancer WEight Loss Study (BWEL Study)	https://clinicaltrials.gov/study/NCT02750826		ACTIVE_NOT_RECRUITING	OTHER: Health Education Program\|OTHER: Weight Loss Intervention	Alliance for Clinical Trials in Oncology	National Cancer Institute (NCI)\|Division of Cancer Control\|NIH Biomarker, Imaging and Quality of Life Studies Funding Program (BIQSFP)\|Canadian Cancer Trials Group	3177	INTERVENTIONAL
NCT03779867	Acute Exercise Intervention in Breast Cancer Survivors	https://clinicaltrials.gov/study/NCT03779867	ACE	ACTIVE_NOT_RECRUITING	BEHAVIORAL: Exercise Intervention\|OTHER: Resting\|OTHER: Biomarker Analysis\|OTHER: Questionnaire Administration	Fred Hutchinson Cancer Center	Breast Cancer Research Foundation	105	INTERVENTIONAL
NCT03091842	Exercise Intervention in Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer	https://clinicaltrials.gov/study/NCT03091842		WITHDRAWN	BEHAVIORAL: Exercise Intervention\|BEHAVIORAL: Exercise Intervention\|BEHAVIORAL: Exercise Intervention\|OTHER: Informational Intervention\|OTHER: Laboratory Biomarker Analysis\|OTHER: Quality-of-Life Assessment\|OTHER: Questionnaire Administration	University of Southern California	National Cancer Institute (NCI)	0	INTERVENTIONAL
NCT04003038	Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery	https://clinicaltrials.gov/study/NCT04003038		RECRUITING	PROCEDURE: Negative Pressure Wound Therapy\|PROCEDURE: Wound Care Management	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	80	INTERVENTIONAL
NCT06399276	4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity	https://clinicaltrials.gov/study/NCT06399276		NOT_YET_RECRUITING	BEHAVIORAL: Weight Loss	University of Colorado, Denver	National Cancer Institute (NCI)	36	INTERVENTIONAL