Related Cancers

Cancer & Obesity Reviews (20 of the most recent)

• Mechanisms by Which Pharmacotherapy May Impact Cancer Risk among Individuals with Overweight and Obesity October 16, 2024
  Diets geared to reduce cancer risk in overweight and obese individuals focus on (1) caloric restriction (every day, some days, or most hours of each day); (2) changes in macronutrient intake; or (3) a combination of the prior two strategies. Diets generally fail because of nonadherence or due to limited sustained weight loss. This is […]
  Edward R Sauter
• The gut microbiome and dietary fibres: implications in obesity, cardiometabolic diseases and cancer October 10, 2024
  Dietary fibres constitute a heterogeneous class of nutrients that are key in the prevention of various chronic diseases. Most dietary fibres are fermented by the gut microbiome and may, thereby, modulate the gut microbial ecology and metabolism, impacting human health. Dietary fibres may influence the occurrence of specific bacterial taxa, with this effect varying between […]
  Nathalie M Delzenne
• Anti-oxidative activity of probiotics; focused on cardiovascular disease, cancer, aging, and obesity October 9, 2024
  By disturbing the prooxidant-antioxidant balance in the cell, a condition called oxidative stress is created, causing severe damage to the nucleic acid, protein, and lipid of the host cell, and as a result, endangers the viability of the host cell. A relationship between oxidative stress and several different diseases such as cardiovascular diseases, cancer, and […]
  Batoul Kavyani
• Overweight and obesity significantly increase colorectal cancer risk: a meta-analysis of 66 studies revealing a 25-57% elevation in risk October 8, 2024
  The incidence of colorectal cancer (CRC) has been steadily rising, and obesity has been identified as a significant risk factor. Numerous studies suggest a strong correlation between excess body weight and increased risk of CRC, but comprehensive quantification through pooled analysis remains limited. This study aims to systematically review and meta-analyze the existing literature to […]
  Zoltan Ungvari
• Body mass index, obesity and risk of prostate cancer: a systematic review and meta-analysis September 30, 2024
  CONCLUSIONS: BMI >25 kg/m² was associated with an increased risk of prostate cancer and mortality.
  Fajar Gemilang Ramadani
• Advancements in Understanding and Preventing Obesity-Related Colon Cancer September 23, 2024
  Obesity and colorectal cancer are global public health issues, with the prevalence of both conditions increasing over the last 4 decades. In the United States alone, the prevalence of obesity is greater than 40%, and this percentage is projected to increase past 50% by 2030. This review focuses on understanding the association between obesity and […]
  Christine Shieh
• The multifactorial effect of obesity on the effectiveness and outcomes of cancer therapies September 23, 2024
  Epidemiology studies have demonstrated a clear association between obesity and the development of several distinct malignancies, with excessive visceral adiposity being an increasingly prevalent feature in patients with cancer presenting for therapeutic intervention. Clinical trials and meta-analyses have helped to inform effective and safe dosing of traditional systemically administered anticancer agents in adult patients with […]
  Joanne Lysaght
• Obesity-Associated Breast Cancer: Analysis of Risk Factors and Current Clinical Evaluation September 17, 2024
  Several studies show that a significantly stronger association is obvious between increased body mass index (BMI) and higher breast cancer incidence. Additionally, obese and postmenopausal women are at higher risk of all-cause and breast cancer-specific mortality compared with non-obese women with breast cancer. In this context, increased levels of estrogens, excessive aromatization activity of the […]
  Atilla Engin
• Obesity-Senescence-Breast Cancer: Clinical Presentation of a Common Unfortunate Cycle September 17, 2024
  There are few convincing studies establishing the relationship between endogenous factors that cause obesity, cellular aging, and telomere shortening. Without a functional telomerase, a cell undergoing cell division has progressive telomere shortening. While obesity influences health and longevity as well as telomere dynamics, cellular senescence is one of the major drivers of the aging process […]
  Ayse Basak Engin
• Obesity and its relationship with cancer September 16, 2024
  The aim of this study is to investigate how excess weight can influence cancer risk and the possible mechanisms involved. For this purpose, a bibliographic review was made of the studies published between 2000 and 2024 that analyze this relationship, as well as specific types of cancer associated with obesity. A significant association was found […]
  Ovidio Hernando-Requejo
• Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer September 9, 2024
  Breast cancer is the most common cancer in women, and incidence rates are rising, it is thought in part, due to increasing levels of obesity. Endocrine therapy (ET) remains the cornerstone of systemic therapy for early and advanced oestrogen receptor-positive (ER + ) breast cancer, but despite treatment advances, it is becoming more evident that […]
  Sohail Rooman Javed
• Addressing Post-Acute COVID-19 Syndrome in Cancer Patients, from Visceral Obesity and Myosteatosis to Systemic Inflammation: Implications in Cardio-Onco-Metabolism August 29, 2024
  Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in the world. The emerging field of cardio-oncology described several shared risk factors that predispose patients to both cardiovascular disease and cancer. Post-acute COVID-19 syndrome is a chronic condition that occurs in many patients who have experienced a SARS-CoV-2 infection, mainly based […]
  Vincenzo Quagliariello
• Obesity-Associated Colorectal Cancer August 29, 2024
  Colorectal cancer (CRC) affects approximately 2 million people worldwide. Obesity is the major risk factor for CRC. In addition, obesity contributes to a chronic inflammatory stage that enhances tumor progression through the secretion of proinflammatory cytokines. In addition to an increased inflammatory response, obesity-associated cancer presents accrued molecular factors related to cancer characteristics, such as […]
  Lucia Gonzalez-Gutierrez
• Obesity and Colorectal Cancer: A Narrative Review August 29, 2024
  Background and Objectives: Cancer is a multicausal disease, and environmental, cultural, socioeconomic, lifestyle, and genetic factors can influence the risk of developing cancer. Colorectal cancer (CRC) stands as the third most common cancer globally. Some countries have observed a rise in the incidence of CRC, especially among young people. This increase is associated with lifestyle […]
  Bárbara Cristina Jardim Miranda
• Epigenetic contribution to the relationship between obesity and cancer August 23, 2024
  Obesity and cancer are two major health issues all around the world due to their elevated prevalence. Several experimental and epidemiological studies have demonstrated the relationship between obesity and cancer, in which obesity is considered a risk factor for cancer development. The ultimate goal of knowing the epigenetic contribution to the relationship between obesity and […]
  Yen-Vy Nguyen Thi
• Phase angle as a potential tool to evaluate chronic inflammatory state and predict quality of life deterioration in women with breast cancer and obesity: A narrative review August 16, 2024
  The interaction between lifestyle--defined more specifically in health care as the personal exposome--and its implications on obesity and breast cancer development highlights the critical role of body composition and inflammation in these patients. There is clear evidence that the personal and internal exposome triggers biochemical, inflammatory, and metabolic reprogramming, which might favor ectopic lipid accumulation […]
  Fernanda Sarahí Fajardo-Espinoza
• Methylsulfinyl Hexyl Isothiocyanate (6-MSITC) from Wasabi Is a Promising Candidate for the Treatment of Cancer, Alzheimer's Disease, and Obesity August 10, 2024
  Methylsulfinyl hexyl isothiocyanate (6-MSITC) isolated from Eutrema japonicum is a promising candidate for the treatment of breast cancer, colorectal and stomach cancer, metabolic syndrome, heart diseases, diabetes, and obesity due to its anti-inflammatory and antioxidant properties. Also, its neuroprotective properties, improving cognitive function and protecting dopaminergic neurons, make it an excellent candidate for treating neurodegenerative […]
  Joanna Bartkowiak-Wieczorek
• A meta-analysis examining the impact of obesity on surgical site wound complications in patients undergoing primary ovarian cancer surgery August 5, 2024
  The meta-analysis sought to evaluate and compare the effect of obesity on surgical site wound problems in subjects after primary ovarian cancer surgery. The results found by this meta-analysis were analyzed, and then odds ratio (OR) and mean difference (MD), at 95% confidence intervals (CIs), were calculated. These models might be dichotomous or contentious, random, […]
  Mohamed S Imam
• Mechanisms by which obesity regulates inflammation and anti-tumor immunity in cancer July 29, 2024
  Obesity is associated with an increased risk for 13 different cancers. The increased risk for cancer in obesity is mediated by obesity-associated changes in the immune system. Obesity has distinct effects on different types of inflammation that are tied to tumorigenesis. For example, obesity promotes chronic inflammation in adipose tissue that is tumor-promoting in peripheral […]
  Cora E Miracle
• Obesity-related cancer and bariatric surgery: A comprehensive systematic review and meta-analysis protocol July 23, 2024
  INTRODUCTION: Obesity is a silent pandemic affecting all ages and is a component of metabolic syndrome. Its treatment is conducted by lifestyle and behavioral changes, pharmacological therapy, and when correctly indicated, bariatric surgery. In recent years, the procedures for weight loss have been investigated due to their relationship with the development of many types of […]
  Isadora de Albuquerque Falcão Feitosa