Related Cancers

Cancer & Obesity Reviews (20 of the most recent)

• Insights into the molecular and genetic role of obesity in breast cancer pathogenesis May 12, 2025
  The epidemic of obesity is a growing concern and is one of the major risk factors for several chronic diseases, including several types of cancers. The correlation of breast cancer with obesity has been extensively studied and involves an interplay of hormonal, metabolic, and genetic factors explored in this review. Inflammation and hormone dysregulation play […]
  Sandeep Mallya
• Evaluating the obesity paradox in patients with sepsis and cancer May 12, 2025
  CONCLUSIONS: The obesity paradox is evident in both short-term outcome (28-day mortality) and long-term outcomes (6-month and 1-year mortality) among patients with sepsis and cancer, particularly in those presenting with lower disease severity. These findings highlight the need for personalized treatment approaches in this complex patient population.
  Chunhong Hou
• Chinese visceral adiposity index outperforms other obesity indexes in association with increased overall cancer incidence: findings from prospective MJ cohort study May 9, 2025
  BACKGROUND: We assessed the associations of visceral adiposity indexes such as Chinese Visceral Adiposity Index (CVAI), Visceral Adiposity Index (VAI), Lipid Accumulation Product (LAP), waist circumference (WC), and waist-hip ratio (WHR) with overall and specific cancer incidence in a Chinese population.
  Mengying Wang
• Role and Significance of MicroRNAs in the Relationship Between Obesity and Cancer May 6, 2025
  MicroRNAs (miRNAs) are small, noncoding RNAs that are essential for regulating gene expression at the posttranscriptional stage. Recent research shows that miRNAs are crucial in the development of two major global health issues: obesity and cancer, two significant health issues worldwide. This study examines the complex mechanisms by which miRNAs govern vital biological processes, including […]
  Ahmed S Doghish
• Global trends in the management of cancer through obesity reduction: a bibliometric based systematic literature review April 22, 2025
  CONCLUSION: The treatment of obesity seems to be emerging as a strategy for the prevention and treatment of cancer. The field is relatively new, publications have begun to emerge in the last 10 years, and there is a growing interest in bariatric surgery as a method to prevent obesity-related cancers.
  Muhammad Hassaan Wali
• Interleukin-33 and Obesity-Related Inflammation and Cancer April 16, 2025
  Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family. It is primarily associated with type 2 immune responses. It interacts with a receptor complex on immune cells in reaction to tissue damage or cellular injury. IL-33 is crucial in immune responses and is involved in various autoimmune and inflammatory diseases. Obesity is marked by […]
  Cameron Kowitt
• From obesity to inflammation: emerging frontiers in prostate cancer and metabolic syndrome studies April 14, 2025
  CONCLUSIONS: The findings provide a thorough understanding of the larger context of this field of study. Future studies need to investigate PCa's metabolic processes and inflammatory mechanism. Furthermore, switching from observational research to meta-analysis offers the possibility of illness prediction and tailored therapies. These results may help researchers navigate the most recent advancements and influence […]
  Xi Xu
• Obesity, overweight and breast cancer: new clinical data and implications for practice April 11, 2025
  Excess bodyweight has negative consequences in breast cancer (BC) patients, significantly increasing the incidence of BC and adversely affecting clinical outcomes in most BC subtypes. This article overviews recent evidence relating to excess bodyweight (particularly obesity) and its effect on treatment in women with BC, focusing on latest evidence, including clinical findings from recently introduced […]
  Laura García-Estévez
• The role of diet, obesity and body composition in epithelial ovarian cancer development and progression: Mechanisms and therapeutic implications April 11, 2025
  Epithelial ovarian cancer (EOC) ranks among the deadliest cancers, with over half of newly diagnosed patients presenting with metastatic disease, highlighting the need for early detection strategies and a deeper understanding of biologic factors that impact EOC progression and treatment response. This paper aims to synthesize the current literature on the association between diet, obesity, […]
  Jessica Suratkal
• Association of past obesity and BMI trajectories with cancer mortality: a prospective cohort study April 8, 2025
  CONCLUSIONS: This study found that past obesity is consistent with the "obesity paradox." In furtherance, a moderately elevated and stable BMI might be associated with lower cancer mortality.
  Huan Zhang
• Vitamin D: What role in obesity-related cancer? April 7, 2025
  Obesity is an important risk factor for incidence and death for many types of cancer. Vitamin D reduces risk of incidence and death for many types of cancer. This review outlines the mechanisms by which obesity increases risk of cancer, how vitamin D reduces risk of cancer, and the extent to which vitamin D counters […]
  Pierrick Martinez
• The effects of obesity on surgical complications and postoperative prognosis of epithelial ovarian cancer: a meta-analysis March 28, 2025
  OBJECTIVE: To comprehensively evaluate and compare surgical outcomes of obese patients versus non-obese patients for surgical complications and postoperative prognosis due to epithelial ovarian cancer (EOC).
  Jingjing Sheng
• Obesity and Risk of Pre- and Postmenopausal Breast Cancer in Africa: A Systematic Review March 26, 2025
  Background and Aims: Several epidemiological studies have investigated the relationship between anthropometric factors and breast cancer (BC), but the results, particularly for premenopausal BC, remain inconsistent and contradictory. The aim of this systematic review is to present an overview of studies examining the association between obesity and BC risk in African women, by menopausal status. […]
  Najia Mane
• The impact of the tumor microenvironment in the dual burden of obesity-cancer link March 24, 2025
  Obesity induces systemic perturbations of tissue homeostasis, leading to dyslipidemia, insulin resistance and chronic state of inflammation. Evidence from clinical and preclinical studies links excess of adiposity with increased cancer incidence and suggests that chronic inflammation may contribute to increased cancer risk in obese patients. Over the last decades of obesity research, multifaced and complicated […]
  Serena Sagliocchi
• A Novel Insight into the Role of Obesity-Related Adipokines in Ovarian Cancer-State-of-the-Art Review and Future Perspectives March 13, 2025
  Ovarian cancer (OC) is one of the most fatal gynecological neoplasms. Meta-analyses have shown that the relationship between body mass index (BMI) and ovarian cancer incidence was detected in some types of ovarian cancer. Chronic inflammation and excessive accumulation of free fatty acids are key adipose tissue-derived factors initiating cancer development. Cancer cells transform adipose-derived […]
  Klaudia Kołakowska
• Unraveling molecular interconnections and identifying potential therapeutic targets of significance in obesity-cancer link March 5, 2025
  Obesity, a global health concern, is associated with severe health issues like type 2 diabetes, heart disease, and respiratory complications. It also increases the risk of various cancers, including melanoma, endometrial, prostate, pancreatic, esophageal adenocarcinoma, colorectal carcinoma, renal adenocarcinoma, and pre-and post-menopausal breast cancer. Obesity-induced cellular changes, such as impaired CD8^(+) T cell function, dyslipidemia, […]
  Alanoud Abdulla
• Targeting obesity, metabolic syndrome, and prostate cancer: GLP-1 agonists as emerging therapeutic agents March 2, 2025
  Prostate cancer (PCa) is known as the second most common cancer and has one of the highest incidences among male cancers in the United States. In addition, obesity and metabolic syndrome are a rising and continuous issue in the United States, with 41.9% of individuals as obese. The importance of highlighting these figures is the […]
  Azura Murphy
• Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer February 27, 2025
  PURPOSEOF REVIEW: Ultra-processed foods (UPFs) are becoming more and more important in daily diets around the world; in some cases, they can account for as much as 60% of daily energy intake. Epidemiological evidence suggests that this shift toward high levels of food processing may be partially responsible for the global obesity epidemic and the […]
  Ioanna A Anastasiou
• Outcomes of Metabolic and Bariatric Surgery in Populations with Obesity and Their Risk of Developing Colorectal Cancer: Where Do We Stand? An Umbrella Review on Behalf of TROGSS-The Robotic Global Surgical Society February 26, 2025
  Introduction: Obesity is a chronic disease associated with increased risk for several cancers, including colorectal cancer (CRC), a leading cause of cancer-related mortality. The majority of CRC cases are associated with modifiable risk factors. Metabolic and bariatric surgery (MBS) is a proven, durable, and successful intervention for obesity. This study aimed to evaluate the impact […]
  Aman Goyal
• Editorial: Obesity and cancer: the possible molecular links February 26, 2025
  No abstract
  Biswarup Basu