Greater weight loss promised by higher-dose Wegovy shot, now approved by FDA

The FDA approved Wegovy HD, a higher-dose semaglutide for weight loss in adults with obesity, offering greater weight reduction, as experts warn of side effects.

The FDA approved Wegovy HD, a higher-dose semaglutide for weight loss in adults with obesity, offering greater weight reduction, as experts warn of side effects.

Stopping GLP-1 drugs like Ozempic quickly erodes heart protection, with two years off the medication raising cardiovascular risk by 22%, a new study finds.

New research suggests that GLP-1s could offer dual benefits for treating both metabolic and mental health issues. Catherine Falls Commercial/Getty Images
A new study found that people taking GLP-1 drugs like Ozempic and Wegovy had a lower risk of worsening depression and anxiety.
The participants also had fewer hospitalizations and required less sick leave from their jobs.
Experts say the drugs’ effects on dopamine signaling and brain inflammation could account for the benefits.
It’s too soon to recommend GLP-1s as a primary treatment for mental health disorders. Further clinical trials are still needed.

MONDAY, March 23, 2026 -- Periconceptional exposure to glucagon-like peptide-1 (GLP-1) receptor agonists is associated with increased odds of preterm birth among women with diabetes, according to a study published online March 18 in Human...

Whether they're using weekly shots or daily pills, more Americans than ever are turning to anti-obesity drugs to lose weight and boost health.

A stronger version of the popular weight loss drug Wegovy is on the way after federal regulators signed off on a higher dose. The U.S. Food and Drug Administration (FDA) approved a 7.2-milligram dose of Novo Nordisk's semaglutide, the active ingredient in Wegovy. Until now, the highest approved dose was 2.4 milligrams, taken as a weekly shot.

Big food companies are starting to market to people on the powerful new obesity meds with labels that say "GLP-1 Friendly." Nutritionists help us decode that message.

Weight-loss injections that have become famous for helping people shed pounds may also help some patients with advanced cancer live longer when the disease has spread to the brain, according to a new study.

GLP-1 medications like semaglutide (Ozempic) may offer unexpected mental health benefits alongside weight loss. A large study found major drops in depression, anxiety, and psychiatric-related hospital visits among users. Even substance use disorders were significantly lower during treatment. Researchers suspect both lifestyle improvements and direct brain effects could be at play.

Protein products are flooding grocery shelves as influencers promote high-protein diets, but nutrition experts caution the anti-carb trend oversimplifies eating.