The Lancet Diabetes & Endocrinology Commission’s comprehensive work on defining and diagnosing clinical obesity, distinguishing it from mere excess adiposity. A large international expert group, including patient representatives, utilized a Delphi-like consensus process to establish objective criteria for clinical obesity in both adults and children, focusing on organ dysfunction directly caused by excess adiposity. The document outlines the multifactorial causes of obesity, explores the pathophysiology of obesity-induced illness across various organ systems, and provides practical recommendations for clinicians on screening, assessment, and treatment goals. The Commission emphasizes that their new definition addresses a conceptual gap by framing obesity as a specific illness rather than solely a risk factor, aiming to reduce stigma and improve access to care.
Audio Overview (Google NotebookLM)
(20 minutes 22 seconds)
