

Could China’s New GLP-1 Drugs Beat Out Ozempic? – Scientific American
Could China’s New GLP-1 Drugs Beat Out Ozempic? Scientific American

5 GLP-1 updates
As GLP-1 medications including Wegovy, Ozempic, Mounjaro and Zepbound reshape diabetes and weight loss care, recent developments such as new partnerships, safety questions and challenges in patient persistence show the

China clears mazdutide as first dual GCG/GLP-1RA for weight loss
Innovent Biologics Inc. announced June 27 that it gained National Medical Products Administration’s (NMPA) approval of mazdutide as a new weight loss therapy for obese or overweight patients in China.

Degree of weight loss affects tirzepatide-linked cardiometabolic risk improvement: Study
For adults with obesity or overweight, tirzepatide-linked improvements in cardiometabolic risk factors are associated with the degree of weight reduction, according to a study published online June 24 in the

Most on Wegovy a Year Later; Food Label Weight Stigma; Make Your Own GLP-1 Drugs?
(MedPage Today) — Over 60% of patients who started semaglutide (Wegovy) for obesity were still taking it a year later; but only one in seven stayed on the drug over

Ozempic-like drug significantly reduces frequency of chronic migraines in pilot study
Migraines are a common ailment worldwide, affecting nearly 15% of the global population. At times, they can be debilitating enough to interfere with daily activities. Despite a multitude of treatment

FDA Accepts Application for Oral Version of Wegovy
The US Food and Drug Administration (FDA) recently accepted a new drug application for oral semaglutide. If approved, it would be the first oral glucagon-like peptide-1 (GLP-1) receptor agonist authorized

Therapeutic horizons in metabolic dysfunction–associated steatohepatitis
Metabolic dysfunction–associated steatohepatitis (MASH), the progressive inflammatory form of MASLD, is now a leading cause of chronic liver disease worldwide. Driven by obesity and type 2 diabetes, MASH significantly increases

Popular weight-loss drugs may ease migraines too
A GLP-1 drug led to fewer days with headaches, a small pilot study of migraine sufferers shows. It may work by lowering pressure inside the head.

Degree of Weight Loss Affects Tirzepatide-Linked Cardiometabolic Risk Improvement
TUESDAY, July 1, 2025 — For adults with obesity or overweight, tirzepatide-linked improvements in cardiometabolic risk factors are associated with the degree of weight reduction, according to a study published

This Ozempic-Like Drug Slashed Migraines by Half in a Small Trial
The drug helped people who couldn’t get relief from existing treatments. It starts with flashes of light. Zig-zag lines float across your vision. You feel a slight tingling in your

Could China’s New Ozempic-like Drugs Beat Out Current Weight-Loss Medications?
GLP-1 drugs currently being tested in China target complications associated with obesity such as heart disease, fatty liver disease and type 2 diabetes

STAT+: Pharmalittle: We’re reading about Novo’s Wegovy launch gaffes, a former Pfizer exec’s subpoena, and more
Top of the morning to you. And a steamy one, it is. In fact, there is more steam rising from the grounds of the Pharmalot campus than from our ritual

The anti-ageing Ozempic effect: How weight loss jabs could help you live longer ‘slashing your risk of dying young’
WEIGHT loss, warding off dementia, ‘curing’ diabetes and now… anti-ageing powers? Is there anything the so-called fat jabs can’t do? ShutterstockVarious studies have found that Ozempic-like fat jabs can help reduce your

How weight-loss jabs like Mounjaro and Ozempic can destroy your pancreas. First the flesh dies… then your organs fail. As they’re linked to ten deaths, doctors’ urgent warning revealed
The MHRA has revealed it’s received more than 560 reports of acute pancreatitis in patients taking GLP-1 injections since they were first approved in the UK.

China clears mazdutide as first dual GCG/GLP-1RA for weight loss
Innovent Biologics Inc. announced June 27 that it gained National Medical Products Administration’s (NMPA) approval of mazdutide as a new weight loss therapy for obese or overweight patients in China.

[Comment] Body composition during major incretin-based weight loss
We have witnessed weight loss of 13–15% with the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide and up to 18–23% with the dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide in

Liraglutide May Reduce Migraine Burden in Adults With Obesity, Migraine
MONDAY, June 30, 2025 — For adults with obesity and migraine, liraglutide reduces migraine burden, with reductions in mean monthly headache days and Migraine Disability Assessment (MIDAS) scores, according to

Could Ozempic Treat Migraines, Too? Small Study Finds Early Promise for GLP-1s
People with unresponsive chronic migraine and obesity experienced substantial relief after they started taking a GLP-1 drug, researchers in Italy have found.

GLP-1s in Neurodegenerative Disease: Hope or Halt?
Neurologists Indu Subramanian and Lorraine Kalia discuss the data on GLP-1 receptor agonists in neurodegenerative diseases and the recent study on exenatide in Parkinson’s disease. Medscape Neurology

Your Weight Matters Region
Your Weight Matters Regional is traveling the country, bringing expert-led education and practical guidance to cities near you. These FREE half-day events are designed to meet you wherever you are

Many People Actually Lose Muscle on a GLP-1. It’s Not Too Hard to Avoid—Here’s How.
This protocol will help.

New book by former FDA head explores the science behind GLP-1 weight loss drugs
According to the CDC, 1 in 5 American adults is living with obesity. In recent years, many have turned to weight loss drugs containing GLP-1, a hormone that slows digestion

With China approval, Lilly and Innovent’s mazdutide breaks into new class for GLP-1 obesity drugs – Fierce Pharma
With China approval, Lilly and Innovent’s mazdutide breaks into new class for GLP-1 obesity drugs Fierce Pharma

OPKO Health (OPK) to Present OPK-88006 Data at ENDO 2025
OPKO Health, Inc. (NASDAQ:OPK) is one of the 10 best healthcare penny stocks to buy according to analysts. On June 25, the company, in partnership with Entera Bio Ltd., announced

Retatrutide: arguable the most effective metabolic drug ever developed. Full steam for LLY
Surprised how little attention Retatrutide is getting, even though it has the potential to be the most effective obesity and metabolic disease drug ever developed. Eli Lilly is leading the

UPSC Key: Roadmap on de-escalation, GLP-1 drugs, and Coastline paradox
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Dietitian Who Lost 60 Pounds With GLP-1 Drug Reveals Foods to Avoid and Prioritize

Hims & Hers (HIMS) Jumps 6.76% Anew as Investors Cheer Weight Loss Drug Fight
Hims & Hers Health, Inc. (NYSE:HIMS) is one of the 10 Stocks Leave Wall Street Stunned. Hims & Hers extended its rally for the second day on Friday, adding 6.76

Why Thousands Are Risking DIY Weight-Loss Injections
High prices and limited insurance coverage have driven a growing number of Americans to seek weight-loss solutions outside the doctor’s office and the law. Online forums, encrypted chat groups, and

768-P: Glucagon-Like Peptide 1 Receptor Agonists and the Risk of Motility-Related Gastrointestinal Adverse Events—A Cohort Study
Introduction and Objective: To assess if glucagon-like peptide-1 receptor agonist (GLP-1 RA) compared with sodium-glucose cotransporter 2 inhibitors (SGLT-2i), is associated with an increased risk of motility-related gastrointestinal (GI) adverse

750-P: ASC30, an Oral GLP-1R Biased Small Molecule Agonist in Participants with Obesity—A First-in-Human Single Ascending Dose Study
Introduction and Objective: ASC30 is an oral GLP-1R biased small molecule agonist without β-arrestin recruitment, discovered and developed in-house at Ascletis. ASC30 has unique and differentiated properties that enable the

758-P: Titration to Maintenance Doses of GLP-1R Agonists for Overweight and Obesity Is Suboptimal for Majority of Patients—Evidence from a Real-World Claims Dataset
Introduction and Objective: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) represent a paradigm shift in treating obesity. The substantial weight loss observed in clinical trials improves weight-related comorbidities. However, weight loss reported

292-OR: Oral Semaglutide and Cardiovascular Outcomes by Baseline A1C and BMI in People with Type 2 Diabetes in the SOUL Trial
Introduction and Objective: In SOUL (NCT03914326), oral semaglutide (sema) 14 mg QD, a GLP-1 receptor agonist, reduced major adverse cardiovascular (CV) event (MACE) risk by 14%. GLP-1RAs are routinely prescribed

How GLP-1 drugs like semaglutide have revolutionised obesity treatment
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The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis by enhancing GLP-1 secretion and L-cell differentiation
Aims/hypothesis: Growing evidence implicates gut microbiota-derived metabolites in metabolic homeostasis. Indole, a microbial tryptophan metabolite, has been reported to enhance Glucagon-like peptide-1 (GLP-1) secretion in vitro, and its derivatives have

Stung By High Prices, Americans Make Their Own Weight-Loss Drugs
SAN FRANCISCO (Reuters) – In what she calls the “wild west” of obesity medicines, Missouri-based Amy Spencer is a pioneer. Each week, the mother of two injects herself with weight-loss

Ozempic And Plastic Surgery Dominate Jeff Bezos’s Wedding As Skinny Stars Shut Down Venice
Hollywood’s upper crust has converged on Venice for the three-day wedding extravaganza of Amazon mogul Jeff Bezos and Lauren Sanchez, with a cluster of snatched waists drawing attention and fueling

J&J dealt blow in fight over its 340B rebate model
A federal judge said the government did not run afoul of the law when it required Johnson & Johnson to seek approval before implementing its proposed 340B rebate model. The

NVO vs. LLY: Which Obesity Powerhouse is the Stronger Bet Now?
Novo Nordisk NVO and Eli Lilly LLY dominate the diabetes and obesity market on the back of the tremendous success of their GLP-1 products. Novo Nordisk markets its semaglutide drugs as Ozempic pre-filled pens

With China approval, Lilly and Innovent’s mazdutide breaks into new class for GLP-1 obesity drugs
With a first-in-class approval in China, Eli Lilly’s GLP-1 development engine has delivered yet again on the obesity front—although local biopharma outfit Innovent Biologics will be the one to reap

The GLP-1 Weight Loss Drug Ozempic Is Reportedly Giving Men A Lot To Brag About, Down Under
Imagine getting rid of your persistent fat layers, while gaining girth down under. That’s a contemporary equivalent to the fabled fountain of youth, and a special class of weight loss

Amgen Looks to Take Share of Booming Obesity Space: Will It Succeed?
Amgen AMGN is one of the several drug makers racing to develop the next blockbuster weight loss drug and take a share of the booming weight loss drug market. The obesity


Does Medicare Cover Ozempic, Zepbound and Other GLP-1 Inhibitors?
GLP-1 drugs, such as Ozempic, are reshaping diabetes care and weight loss. Find out if Medicare covers them and if they’re right for you.

Innovent brings a new mechanism to obesity market with China approval
Innovent said on Friday that its obesity medicine mazdutide has been approved in China, becoming the first dual GLP-1/glucagon agonist to be greenlit for the disease anywhere in the world.

GLP-1s linked to cases of illness and death
GLP-1 drugs, which have seen widespread success, have been linked to a number of cases of pancreatitis in the UK, which have led to hospitalisations and even deaths.

STAT+: Pharmalittle: We’re reading about the gray market for obesity meds, an RSV drug recommendation, and more
And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans.

New Ozempic alternative only needs to be taken once a month and leads to ‘substantial weight loss’
A NEW weight loss jab that only needs to be taken once monthly leads to “substantial weight loss”, according to early trials. Drugs like Wegovy and Mounjaro – or diabetes

Why Shares in Amylyx Pharmaceuticals Soared This Week
Shares in Amylyx Pharmaceuticals (NASDAQ: AMLX) were up almost 28% in the week to Friday morning. The move comes after an analyst at Guggenheim initiated coverage of the small-cap stock

Why Shares in Amylyx Pharmaceuticals Soared This Week
Shares in Amylyx Pharmaceuticals (NASDAQ: AMLX) were up almost 28% in the week to Friday morning. The move comes after an analyst at Guggenheim initiated coverage of the small-cap stock

Novo Nordisk’s Pricing Crossroads: Regulatory Risks and Competitive Pressures Threaten GLP-1 Dominance – AInvest
Novo Nordisk’s Pricing Crossroads: Regulatory Risks and Competitive Pressures Threaten GLP-1 Dominance AInvest

I’ve gone from a size 20 to an 8 & lost 8 stone on Mounjaro – I’ve had hair loss but don’t mind, I like my locks thinner
A WOMAN has revealed that thanks to Mounjaro, she has lost eight stone and has dropped from a size 20 to an 8. But Alexandra, 33, who is from the

Diabetes Drug Tied to Decreased Dementia Risk in T2D
Semaglutide is linked to a reduced risk for Alzheimer’s disease-related dementia in patients with diabetes vs other antidiabetic drugs, a new study suggests. Medscape Medical News

We’re learning more about what weight-loss drugs do to the body
Weight-loss drugs are this decade’s blockbuster medicines. Drugs like Ozempic, Wegovy, and Mounjaro help people with diabetes get their blood sugar under control and help overweight and obese people reach

Weight-loss jabs linked to hundreds of cases of life-threatening illness and 10 deaths
Since the GLP-1 drugs, including Mounjaro, Ozempic and Wegovy, were licensed, there have been hundreds of reported cases of acute and chronic pancreatitis among people taking them, figures from the

Pancreatitis: The life-threatening reaction linked to weight loss injections
Some cases of pancreatitis have been reported to be linked to GLP-1 medicines. Here’s what we know

After Ozempic, Women On Mounjaro May Be Overlooking A Serious Pancreas Problem
Women on Mounjaro may miss signs of pancreatitis. Learn the symptoms, risks, and what UK health authorities are doing to monitor GLP-1 weight loss drugs.

‘Organ-Destroying’ Ozempic And Mounjaro Have Already Claimed 10 Lives, Experts Say
The weight-loss injection boom that swept through Hollywood and boardrooms alike is now facing a potentially deadly reckoning. The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has launched a

Ozempic-Style Drugs Linked To Hundreds of Illnesses and Deaths
The United Kingdom’s health regulator is investigating weight loss jabs like Ozempic and Mounjaro after linking it to hundreds of severe illnesses and even a handful of deaths. As the

What Are GLP-1 Supplements?
GLP-1 has become a hot topic in health and wellness. If you’ve heard of medications like Ozempic or Wegovy, then you’ve already heard about GLP-1. These drugs work by mimicking

UK investigates weight-loss jab risks after many hospitalised with pancreatitis
The UK’s MHRA and Genomics England have launched a groundbreaking study to investigate whether genetics play a role in developing acute pancreatitis after taking GLP-1 weight-loss drugs like Ozempic, Mounjaro,

Vaccine policy frays, CDC nominee in the hot seat, & obesity drug side effects
What does the fracturing of vaccine advice and policy mean for the U.S. health care ecosystem? Will the potential head of the Centers for Disease Control and Prevention stand up

The Week in AgriFoodTech: Climatiq raises $11.7m, Doktar bags $8.7m, Planetary acquires Libre Foods
This week German startup Climatiq secured $11.7m to embed carbon intelligence into daily business operations and Turkish farm digitization startup Doktar secured $8.8m to expand AI-driven agtech globally. Elsewhere, PepsiCo

VKTX Initiates Phase 3 Study on Obesity Candidate VK2735
Viking Therapeutics VKTX announced that it has initiated the phase III VANQUISH program, evaluating the subcutaneous (SC) formulation of its experimental obesity drug VK2735 in adult patients with or without type

Weight loss and diabetes jabs linked to potentially fatal side effect
Weight loss and diabetes jabs taken by more than a million people in Britain have been linked to a potential serious side effect, with some deaths, according to data from

More Evidence for Ocular Adverse Events with GLP-1–Receptor Agonists
GLP-1 agonists were linked to greater risk for neovascular age-related macular degeneration.

Only 8% of GLP-1 users stay on treatment after 3 years: Study
After three years, only about 1 in 12 individuals taking GLP-1s to treat obesity remained on the therapy, according to a Prime Therapeutics study published on June 25. Prime is

Can LLY’s Next-Generation Obesity Pipeline Fuel Further Growth?
Eli Lilly LLY has experienced significant growth in the past few years, particularly driven by the success of its popular tirzepatide injections, Mounjaro for type II diabetes (T2D) and Zepbound

Will MRK’s Growing Pipeline Help Navigate the Looming Keytruda LOE?
Merck MRK has built a substantial portfolio of new products and pipeline candidates in areas like oncology, vaccines, neuroscience, and infectious disease. Merck’s phase III pipeline has almost tripled since 2021,

Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation
Over 100 cases of acute pancreatitis have been reported to UK health regulators this year, many tied to the newest GLP-1 drug on the market.

Podcast: Is Ozempic (Semaglutide) Safe? Does It Increase Cancer Risk?
There are serious potential side effects to GLP-1 weight-loss drugs. This episode features audio from: https://nutritionfacts.org/video/is-ozempic-semaglutide-safe-does-it-increase-cancer-risk/ Visit the video page for all sources and doctor’s notes related to this podcast.

Can drinking instant coffee make you go blind? Twin doctors answer | Morning in America
Drs. Idries and Jamil Abdur-Rahman answer medical questions about the health effects of drinking instant coffee, the possibility of GLP-1 medications increasing the risk of dementia, and pregnancy diets on

Annals of Innovative Food Marketing: Snacks to Stoners
It’s taken me a couple of months to get to this but a reader in Montreal wanted to be sure I did not miss this article: Twinkies’ New Owner Courts

STAT+: AI in pharma, the obesity iceberg, & Novartis tightens up
Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Today, we uncover the extent of low-quality generic cancer

High Costs Likely Lead to Early Semaglutide Discontinuation
Many semaglutide users deviate from recommended dose‐escalation schedules and discontinue treatment, highlighting the need for policy interventions to reduce financial barriers. Medscape Medical News

Semaglutide Benefits Adults With Type 1 Diabetes + Obesity
Once-weekly semaglutide improved glycemia and reduced weight in adults with type 1 diabetes and obesity without increasing hypoglycemia. Medscape Medical News

If you take a GLP-1 medicine and have been hospitalised by acute pancreatitis, the Yellow Card Biobank wants to hear from you
GLP-1 medicines are licensed for Type 2 diabetes and weight management, and include the branded products Ozempic, Mounjaro and Wegovy

Ozempic-like fat jabs taken by millions linked to 560 cases of killer side effect and 10 deaths, health officials warn
FAT jabs have been linked to hundreds of people falling sick and some dying from an organ-destroying illness, the UK’s drug watchdog has warned. Brits have reported falling seriously ill with pancreatitis, a

Eli Lilly to launch Mounjaro KwikPen for type 2 diabetes in India
Eli Lilly is set to launch Mounjaro in KwikPen, a user-friendly, prefilled pen for weekly administration, in India, following regulatory approval. This offers a convenient option for adults with type

Pancreatitis: The life-threatening reaction linked to weight loss injections
Some cases of pancreatitis have been reported to be linked to GLP-1 medicines. Here’s what we know

India approves Eli Lilly’s Mounjaro KwikPen for diabetes and obesity, offering a novel dual-action therapy
NEW DELHI: India’s drug regulator has approved Eli Lilly and Company’s diabetes and obesity drug Mounjaro in a KwikPen presentation, the pharmaceutical giant announced on Thursday. The Central Drugs Standard

What is pancreatitis? The life-threatening reaction linked to weight loss jabs
Some cases of pancreatitis have been reported to be linked to GLP-1 medicines. Here’s what we know

I started taking Mounjaro at 50 to lose weight – it worked, but I’m exhausted
My weight has always been the one thing I had felt in control of, since I was a teenager. All it took was a little willpower, even after two pregnancies,

Hundreds of weight loss and diabetes jab users report pancreas condition
Hundreds of weight loss and diabetes jab users have reported problems with their pancreas, with some cases proving fatal, according to new data. Data from the medicines regulator shows that

Big pharma was behind the fat acceptance movement.
I really think big pharma was behind the whole fat acceptance movement. Obesity has sky rocketed over the last few decades, alongside big pharma profits. It’s like the whole saying

Weight-loss jabs linked to hundreds of cases of life-threatening illness and 10 deaths
Since the GLP-1 drugs, including Mounjaro, Ozempic and Wegovy, were licensed, there have been hundreds of reported cases of acute and chronic pancreatitis among people taking them, figures from the

Experts demand study into weight loss jab side effects amid rapid rollout
Some people may be at more risk from bad reactions due to their genes (Picture: Getty) Hundreds of people have reported problems with their pancreas after taking weight loss drugs,

THERE ARE NEWER DRUGS ON THE WAY THAT DON’T TO THIS: Studies exploring muscle loss from GLP-1 drugs
THERE ARE NEWER DRUGS ON THE WAY THAT DON’T TO THIS: Studies exploring muscle loss from GLP-1 drugs. I’d like to see a medication that combines fat loss with myostatin

Hundreds of weight loss and diabetes jab users report pancreas problems
UK health officials launch study into side-effects of weight loss drugs after increased reports of acute pancreatitis Hundreds of people have reported problems with their pancreas linked to taking weight

Novo Nordisk A/S (NVO): A Bull Case Theory
We came across a bullish thesis on Novo Nordisk A/S on Kontra Investments’ Substack by Kontra. In this article, we will summarize the bull’s thesis on NVO. Novo Nordisk A/S’s share was

Could Ozempic Lower Your Risk of Dementia?
Originally designed to treat type 2 diabetes, GLP-1 medications like Ozempic and Wegovy quickly made it into the hands of every now-formerly hefty person in your life. A new study

Novo Nordisk Has Made a Fortune With Ozempic, but It Knows Its Success Won’t Last Forever. So, It Has Already Developed Two Substitutes
The market for weight-loss drugs continues to grow, but the competition for the largest share of this expanding “pie” is intense. The American pharmaceutical giant Eli Lilly and Co. is

Monthly shot cuts body weight by 16% in groundbreaking obesity trial
A new drug from California-based pharma company Amgen, which has concluded a phase II trial, shows promise as a powerful treatment for obesity. With just a once-monthly shot of ‘MariTide,’

The J. M. Smucker Company (SJM) I Told Them Not To Buy Twinkies!, Says Jim Cramer
The J. M. Smucker Company (NYSE:SJM) is one of the Jim Cramer Reveals Potential US Rare Earth Trump Card & Discusses These 11 Stocks. The J. M. Smucker Company (NYSE:SJM)

STAT+: Novo Nordisk, seen as lagging in obesity drug race, says it’s playing the long game
How did Novo Nordisk get to the position it’s in now — with its stock halved over the past year and the company widely seen as trailing Eli Lilly in

Tesla’s Robotaxi Rollout
In this podcast, Motley Fool Chief Investment Officer Andy Cross and contributors Jason Hall and Matt Frankel discuss: Fair Isaac Corp. to include buy now, pay later data. The importance

Two ‘Spectacular’ Studies & Other Movement Disorder Updates
Studies on stem cell therapy, GLP-1 drugs, and a new infusion pump are discussed by Professor Diener in this update on movement disorders. Medscape Neurology

#ADA25: BrightGene seeks a partner for Zepbound-beating obesity shot
A Shanghai-based biotech, previously known as a generics and manufacturing player, posted mid-stage results suggesting its incretin drug might be one of the most powerful to have reached the clinic.

More people staying on a GLP-1 for weight loss after one year
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