This review article explores the potential of precision medicine to improve obesity management, moving away from the current trial-and-error approach for selecting medications. It highlights that while lifestyle interventions and existing antiobesity medications can lead to weight loss, there is significant variation in individual responses. The authors propose that tailoring treatments based on behavioral and physiological traits, as well as incorporating insights from genetics and multi-omics data, could lead to better outcomes. Identifying specific obesity phenotypes and understanding how different medications impact these traits is presented as a promising path for personalized therapy.
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(18 minutes 13 seconds)
