The anti-ageing Ozempic effect: How weight loss jabs could help you live longer ‘slashing your risk of dying young’

WEIGHT loss, warding off dementia, ‘curing’ diabetes and now… anti-ageing powers? Is there anything the so-called fat jabs can’t do? ShutterstockVarious studies have found that Ozempic-like fat jabs can help reduce your risk of chronic illness and leading causes of death[/caption] While a medicine that reverses the clock would be a miracle, we’re not quite there, yet. But scientists […]

China clears mazdutide as first dual GCG/GLP-1RA for weight loss

Innovent Biologics Inc. announced June 27 that it gained National Medical Products Administration’s (NMPA) approval of mazdutide as a new weight loss therapy for obese or overweight patients in China. Mazdutide is a dual glucagon/glucagon-like peptide-1 (GCG/GLP-1) receptor agonist originally discovered by Eli Lilly and Co., of Indianapolis.

[Comment] Body composition during major incretin-based weight loss

We have witnessed weight loss of 13–15% with the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide and up to 18–23% with the dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide in people with obesity but without diabetes.1 In people with type 2 diabetes, weight loss seems to be somewhat lower, at 8–9% with semaglutide and 11–13% […]