Hormone Therapy Enhances Tirzepatide Weight Loss in Menopause

The source discusses research indicating that postmenopausal women on hormone therapy (HT) experience significantly greater weight loss when treated with tirzepatide, an obesity medication, compared to those not on HT. This effect mirrors prior findings with semaglutide, another weight-loss drug, suggesting a synergistic interaction where HT enhances the efficacy of these medications in this demographic. […]

WeightWatchers Returns With a Plan for the New GLP-1 World

WeightWatchers is no longer content to stew about its seemingly slender prospects in the Wegovy era.  After the GLP-1 onslaught plunged the company into Chapter 11 submission in May, the dieting brand emerged from bankruptcy last week to announce it had successfully trimmed the fat from its considerable debt load, built a strategy for success […]

Ozempic for addiction: How an elite rehab center is using GLP-1s to ‘obliterate’ all kinds of cravings

WERNERSVILLE, Pa. — To make sense of the reds and greens dancing across a computer monitor displaying a scale image of a human brain, one requires a vivid vocabulary. At this upscale addiction treatment facility, “neurofeedback therapy” and “quantitative electroencephalogram” are part of the holistic, no-expenses-spared treatment philosophy on offer.  But customized brain scans aren’t […]

Amylyx Pharmaceuticals Presents New Exploratory Analyses from Phase 2 and Phase 2b Clinical Trials of Avexitide in Post-Bariatric Hypoglycemia at ENDO 2025

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (“Amylyx” or the “Company”) today announced the presentation of new exploratory analyses from the Phase 2 PREVENT and Phase 2b clinical trials of avexitide, an investigational, first-in-class glucagon-like peptide-1 (GLP-1) receptor antagonist for the treatment of post-bariatric hypoglycemia (PBH) at the Endocrine Society’s annual meeting (ENDO 2025). In […]

Scientists Gene Hack Mice So Their Livers Produce Their Own Ozempic-Like Drug

Scientists have gene-hacked mice to produce their own Ozempic-like drugs — possibly, and provocatively, perhaps paving a path for humans to do so themselves one day. In a new study published in the journal Communications Medicine, researchers from Japan’s University of Osaka successfully gene-edited mice livers to produce exenatide, a first-generation diabetes drug and predecessor to […]

Hormone therapy supercharges tirzepatide, unleashing major weight loss after menopause

Postmenopausal women struggling with weight loss may find a powerful solution by combining the diabetes drug tirzepatide with menopause hormone therapy. A Mayo Clinic study revealed that this dual treatment led to significantly greater weight loss than tirzepatide alone. Women using both treatments lost 17% of their body weight on average, compared to 14% in those not using hormone therapy—and nearly half achieved dramatic 20%+ weight loss.