💊 Obesity Drug Pipeline: GLP-1’s and Others MOAs for the Next Three Years…

(MOA = Mechanism of action.) Comprehensive view of the GLP‑1 and obesity-focused drug pipeline expected over the next three years (mid‑2025 to mid‑2028): 1. Dual & Triple Agonists (Injectable)Retatrutide (Eli Lilly): GLP‑1/GIP/glucagon triple agonist. Phase 2 showed ~24% weight loss at high dose over 48 weeks (Yahoo Finance, Wikipedia). Phase 3 expected in 2026–2027.CagriSema (Novo Nordisk): Semaglutide […]
Experts Recommend Healthy Lifestyle Changes Alongside GLP-1 Drug Use

By Dennis Thompson HealthDay ReporterWEDNESDAY, July 16, 2025 (HealthDay News) — GLP-1 weight-loss drugs like Ozempic and Zepbound are so effective…
The End of the Funny Fat Lady

Photo-Illustration: Tina Tona; Photographs: Courtesy of Everett Collection; Netflix; Alamy Stock Photo; Getty Images In the first episode of the romantic-comedy series Too Much, heartbroken 30-something Jessica (Megan Stalter) breaks into an apartment she used to live in with her ex, Zev (Michael Zegen). We know this is a mess in the making from the […]
How GLP-1s Are Breaking Life Insurance

Ashwin Sharma, GLP-1 Digest Patients look healthy on paper. Two years later, they’re high-risk again.
A Million Veterans Gave DNA To Aid Health Research. Scientists Worry the Data Will Be Wasted.

One of the world’s biggest genetic databases comprises DNA data donated over the years by more than a million retired military service members. It’s part of a project run by the Department of Veterans Affairs. The initiative, dubbed the Million Veteran Program, is a “crown jewel of the country,” said David Shulkin, a physician who […]
4Moving Biotech Enrolls First Patient in Phase 2a Trial of 4P004, a Potential First-in-Class GLP-1 Therapy for Knee Osteoarthritis

LILLE, France & PARIS–(BUSINESS WIRE)–4Moving Biotech Enrolls First Patient in Phase 2a Trial of 4P004, a Potential First-in-Class GLP-1 Therapy for Knee Osteoarthritis.
GLP-1 weight loss drugs increase risk of acid reflux, gastroesophageal reflux disease (GERD), study of people with type 2 diabetes on the drugs finds. >90% of GERD complications involved Barrett esophagus, in which acid damage changes the tissue lining of the esophagus and increases cancer risk.

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This week’s books in Health, Mind and Body

Here are this week’s new releases for the category ‘Health, Mind and Body’. ★ Our Staff Pick ★ Living Your Healthiest Semaglutide Life: A Complete Guide to Nutrition and Mindset While on GLP-1 Medications By Summer Kessel Publisher: Fair Winds Press Publication date: July 15, 2025 ISBN: 9780760396162 Format: Paperback Share this book on Twitter […]
This week’s books in Nonfiction

Here are this week’s new releases for the category ‘Nonfiction’. ★ Our Staff Pick ★ The Idaho Four: An American Tragedy By James Patterson (Author), Vicky Ward (Author) Publisher: Little, Brown and Company Publication date: July 14, 2025 ISBN: 9780316572859 Format: Hardcover Share this book on Twitter | Facebook The Forgotten Toolbox: Old-School Tools That […]
States Are Walking Back Medicaid Coverage for GLP-1s

(MedPage Today) — California recently passed a budget that eliminated Medicaid coverage for GLP-1 agonists for weight loss. Unlike other serious, relapsing-remitting, chronic diseases, the highly-effective medications that treat obesity are not…