💲 Tirzepatide: A Cost-Effective Path to Obesity Management

This academic article presents a cost-effectiveness analysis of tirzepatide, a medication for managing overweight and obesity, comparing it against lifestyle modification (LSM) alone. Researchers used a simulation model to project lifetime health outcomes and costs for patients, focusing on complications like cardiovascular events, type 2 diabetes, cancer, osteoarthritis, and sleep apnea. The study concluded that all tested doses of tirzepatide were cost-effective alternatives to LSM, falling […]

Oral Semaglutide Offers Kidney Benefits in T2D

In a real-world setting, the administration of oral semaglutide leads to a significant reduction in the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and albuminuria. Medscape News UK

STAT+: Senators reveal how much Lilly, Pfizer paid telehealth companies

Over the last nine months, four senators led by Sen. Dick Durbin (D-Ill.) have conducted an inquiry into the growing partnerships between direct-to-consumer telehealth companies and pharmaceutical manufacturers. In the last two years, both Pfizer and Eli Lilly launched websites that, among other things, connect patients with a telehealth provider for conditions their medications treat.  […]

Prevalence of SGLT2 inhibitor and GLP1 receptor agonist prescriptions in type 2 diabetes patients with and without chronic kidney disease: Analysis of an Australian primary care dataset

Abstract Aims Sodium-glucose co-transporter 2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP1-RA) have cardio-kidney-metabolic benefit. This study aimed to understand the prevalence of prescription of SGLT2 inhibitors and GLP1-RA among patients with T2DM with and without chronic kidney disease (CKD) in Australian primary care. Materials and Methods We conducted a retrospective, cohort study […]

[Comment] Beyond a singular focus on GLP-1: why we need a new nomenclature now

The development of glucagon-like peptide-1 (GLP-1)-based therapies for type 2 diabetes and obesity illustrates a remarkable evolution in scientific understanding and therapeutic innovation.1 As the field moves rapidly beyond a singular focus on GLP-1 receptor agonism, the language surrounding these new and emerging therapies should also evolve, capturing the growing complexity and ambition behind these […]

“Ozempic Butt” Is a Real Side Effect of the Drug – Here’s What It Means

Image Source: Getty / Luis Alvarez By now, you’ve probably heard all about Ozempic. The popular drug is a brand name for semaglutide, which is primarily used to help people with type 2 diabetes better manage their symptoms. However, over the last few months, conversations around the injection have shifted, thanks to people starting to […]