Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes

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‘Exploding’ pills could deliver insulin without a needle

Researchers have created a pill that could effectively deliver insulin and other injectable drugs, making medicines for chronic illnesses easier for patients to take, less invasive, and potentially less expensive. Along with insulin, it also could be used for semaglutide—the popular GLP-1 medication sold as Ozempic and Wegovy—and a host of other top-selling protein-based medications […]
ENDO: Older Age, Female Sex Tied to Greater Muscle Loss With Semaglutide

THURSDAY, July 17, 2025 — Older age and female sex may be associated with greater muscle loss in adults with obesity prescribed semaglutide, and greater muscle loss is independently associated with less improvement in glucose homeostasis, according…