Tirzepatide for Weight Loss in Non-Diabetics: A Meta-Analysis
Kommu S, Sharma PP, Gabor RM. Efficacy and Safety of Tirzepatide on Weight Loss in Patients Without Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Obes Rev. 2025 Jun 13:e13961. doi: 10.1111/obr.13961. Epub ahead of print. PMID: 40510020. This article presents a systematic review and meta-analysis on the efficacy and safety of tirzepatide for weight loss in […]
Advice for trying GLP-1 drugs for weight loss from a doctor who’s been there
Former FDA chief Dr. David Kessler says the new weight-loss drugs are a powerful tool to fight obesity. But they come with pitfalls. Here’s his tips for how to use them successfully.
McDonald’s in Trouble as Ozempic Takes Hold
Broken ice cream machines aren’t the only thing bedeviling stalwart fast food chain McDonald’s. Financial services firm Redburn Atlantic put the company’s stock in the bear category, coinciding with a slumpy week in which it lost about three percent of its value — because analysts are betting that GLP-1 agonist weight loss drugs like Ozempic […]
The economics of GLP-1s from the pharmacy’s point of view
“Over the past year, my pharmacy spent $2m+ buying GLP-1s and lost $26k+ dispensing them.” I assumed pharmacies were also making a ton of money off the GLP-1 craze, but apparently not. Interesting read from the owner of CO Bigelow about how it looks from the pharmacy side. (Requires email signup)
Efficacy and Safety of Tirzepatide on Weight Loss in Patients Without Diabetes Mellitus: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
ABSTRACT Tirzepatide has positive effects on weight loss in individuals with overweight or obesity. Considering its broad side-effect profile, its efficacy and safety in individuals without diabetes mellitus (DM) are yet to be fully understood. To address this, we conducted a comprehensive meta-analysis of six randomized trials on individuals with overweight or obesity, without DM, […]
Oxytocin modulates insulin and GLP-1 secretion in pancreatic islets
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The ‘Natural’ Alternative to Ozempic Sounds Great and Is Much Cheaper. The Problem Is Taking It Seriously
Like all revolutions, Ozempic came with promises and a hidden price. Then came the side effects, cost and need for a prescription. As its shadow grows, an alternative option is emerging that doesn’t require injections, thanks to an ancient seed. The husk of a seed. What started as a traditional remedy in South Asia is […]
Wegovy and Mounjaro might affect how well your contraceptives work – here’s why
The UK’s medicine regulator has issued a warning to those taking oral contraceptives. MillaF/ Shutterstock Weight loss drugs, including Wegovy (semaglutide) and Mounjaro (tirzepatide), are becoming increasingly popular among those trying to lose weight. But a rise in so-called “Ozempic babies” has led the UK’s medicines regulator to issue guidance on their use by women […]
Watch: On good and bad bacteria, why micronutrients in food matter, and more
Catch expert insights from Dr. V. Mohan on GLP-1 receptor agonists and how they’re revolutionising diabetes and obesity care.
Life After GLP-1s: New Report Shows How to Avoid Weight Regain
What You Should Know: – A new report released by Virta Health, a leader in diabetes reversal and sustainable weight loss, offers an optimistic counter-narrative to the prevailing belief that weight regain is inevitable after stopping GLP-1 medications. The findings show that a structured, medically guided off-ramp combined with lifestyle support leads to sustained success, […]