ClinicalTrials.gov – Who, what, when, and where.

ClinicalTrials.gov is a public database maintained by the U.S. National Library of Medicine (NLM) at the National Institutes of Health (NIH). It provides detailed information about clinical studies involving human participants, conducted worldwide. Key Features:Registry: Researchers and sponsors (such as pharmaceutical companies, academic institutions, and government agencies) are required or encouraged to register their clinical […]

What are Clinical Trials and why do we need them?

Clinical trials are carefully designed research studies conducted in humans to evaluate the safety, efficacy, and overall benefit of medical interventions such as drugs, biologics, or devices. They progress through phases 1 to 4, each with distinct goals, methods, and regulatory requirements. Below is a full explanation of each phase: 🔬 Preclinical Studies (Before Phase […]

It’s OK not to be fat

“Pharmacist Holding a Box of Ozempic” by chemist4u, CC BY 2.0 “O God, give us the serenity to accept what cannot be changed, the courage to change what can be changed, and the wisdom to know the one from the other.” — Winnifred Wygal “Put the fork down!” — Denis Leary I was going to […]

Omada Health Shares Soar After IPO as GLP-1 Drugs Fuel Interest – WSJ

Omada Health Shares Soar After IPO as GLP-1 Drugs Fuel Interest  WSJ Omada shares rise 21% in Nasdaq debut after health tech company’s IPO  CNBC Omada Health goes public at $23 per share, marking second major digital health IPO in 2025  Yahoo Finance Omada Health IPO signals healthier market, avoids ‘down-round’ trend  TechCrunch Diabetes startup Omada Health finally went […]

Popular weight loss drug could cause sudden blindness – EU’s health watchdog

The producer of Ozempic was advised to list the serious eye condition as a side effect The European Medicines Agency (EMA) has concluded that semaglutide-based medications – including Ozempic, Wegovy, and Rybelsus – increase the risk of a serious eye condition that can lead to sudden vision loss. Following a comprehensive safety review, the EMA’s […]

GLP-1 Drugs Linked to Age-Related Macular Degeneration, Study Finds

GLP-1 drugs like Ozempic could lead to a higher risk of wet age-related macular degeneration in people with type 2 diabetes. Westend61/Getty Images GLP-1 drugs are associated with a higher risk of “wet” age-related macular degeneration in people with type 2 diabetes, according to a new study. Researchers found that the risk substantially increased the […]

EMA warns Ozempic linked to ‘very rare’ side effect

The EMA’s safety committee has issued a warning that the GLP-1 receptor agonist Ozempic (semaglutide, Novo Nordisk A/S) can cause an acute eye condition in which the optic nerve is damaged by a sudden loss of blood supply. After reviewing several large epidemiological studies, clinical trial and in-market data, EMA’s Pharmacovigilance Risk Assessment Committee has […]

The True Cost of “Optimal” Health

“I want to know I’m doing absolutely everything I can to preserve my health for as long as possible.” We hear this kind of thing a lot. People tell us they not only want to stay in good shape as they age, they also want to outlive their peers and age expectancies. Imagine you could […]