Fractyl Rejuva GLP-1 Gene Therapy Data at ASGCT 2025
The sources discuss Fractyl Health’s Rejuva GLP-1 gene therapy platform, highlighting preclinical data presented at ASGCT 2025 for its candidate RJVA-001. This research indicates that a single dose of RJVA-001 in animal models durably improves metabolic markers related to type 2 diabetes and obesity, achieving similar effects as existing GLP-1 drugs but with significantly lower systemic exposure, potentially leading to fewer […]
Effects of GLP‐1 receptor agonists on incidence and outcomes of ischemic stroke and myocardial infarction: A systematic review and meta‐analysis
Abstract Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) demonstrate cardiovascular benefits beyond glycemic control, but the benefits of protection across cerebrovascular and cardiovascular territories remain incompletely studied in the literature. We aim to evaluate whether GLP-1 RAs provide balanced protection against stroke and myocardial infarction (MI) and identify factors that modify this protection. Methods We […]
How to Mimic the Effects of GLP-1 Drugs Through Diet
Mary J. Scourboutakos, Conv Despite the popularity of semaglutide drugs like Ozempic and Wegovy for weight loss, surveys suggest that most people still
Who needs Ozempic? Dietary strategies and natural supplements boost GLP-1 hormone for healthy weight loss without medications
(NaturalNews) Foods rich in soluble fiber (beans, oats, avocados), monounsaturated fats (olive oil, nuts) and lean protein can stimulate GLP-1 production â a …
GLP-1 Leads to Similar Cognitive Outcomes as Other Diabetes Drugs, Trial Data Show
(MedPage Today) — Cognitive performance was not different among four classes of glucose-lowering medications for type 2 diabetes, data from the GRADE clinical trial showed. Cognitive performance at 4.1 years of follow-up was similar in participants…
Companies sidestep FDA deadline on Ozempic copies
An FDA deadline instructing compounding pharmacies and telehealth companies to stop selling compounded versions of Ozempic and Zepbound has not stopped the copycat market, The Wall Street Journal reported May 18. After the FDA declared the yearslong shortages of Novo Nordisk’s Ozempic and Wegovy and Eli Lilly’s Zepbound and Mounjaro as resolved, a group of […]
Junk food is addictive. Drugs like Ozempic treat addiction. But when will we tackle Big Food like we did Big Tobacco?
Polina Tankilevitch/Pexels Since Ozempic hit the public consciousness as a weight-loss medication, one in eight Americans have tried it (or a version of it) to lose weight. This is remarkable: less than five years ago, most people reading this would not have known these drugs existed. As availability of Ozempic and other GLP-1 based medications […]
Scientists Share Simple Foods That Actually Burn Fat Even Better Than Ozempic
It’s likely that you’ve heard about the “Ozempic epidemic” – people using this anti-diabetic medication for their weight loss. 2 in 5 adults who use these medications use them solely to lose weight. This got to the point where there have been reported shortages of it, along with medications like Wegovy and Mounjaro, which also provide […]
Zepbound More Effective for Weight Loss Than Wegovy, Eli Lilly Trial Shows
Tirzepatide (Zepbound) led to more weight loss than semaglutide (Wegovy) in a clinical trial funded by Eli Lilly. Shelby Knowles/Bloomberg/Getty Images Zepbound outperformed Wegovy for weight loss in a clinical trial sponsored by Eli Lilly. Participants who received tirzepatide, the active ingredient in Zepbound, also had greater reductions in waist size and more significant improvements […]
GLP-1 Receptor Agonists Not Linked to Increased Risk of Psychiatric Adverse Events, Depression
MONDAY, May 19, 2025 — For patients with overweight/obesity and/or diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment is not associated with an increased risk for psychiatric adverse events or worsening depressive symptoms…