Response to Comment on Wong et al. Efficacy of GLP-1 Receptor Agonists on Weight Loss, BMI, and Waist Circumference for Patients With Obesity or Overweight: A Systematic Review, Meta-analysis, and Meta-regression of 47 Randomized Controlled Trials. Diabetes Care 2025;48:292–300
We appreciate the insightful comments provided by Huang (1) on our study (2) and are grateful for the opportunity to further elaborate on the points raised. In this reply, we present the results of funnel plots, Egger test, and trim-and-fill analyses for the three study outcomes, mean differences in weight, BMI, and waist circumference, to […]
Taking a GLP-1 for PCOS May Help With Symptoms. Here’s Why and What to Know
The research is early-stage, but doctors are hopeful about the hormonal upsides of these weight-loss drugs.
Vida Health Data Shows Obesity Success Beyond GLP-1 Medications
What You Should Know: – Vida Health, a virtual, personalized obesity care provider that helps patients manage obesity and related conditions, today announced outcomes from its Clinical Obesity Management Program, which demonstrate that most patients do not require expensive GLP-1s to achieve sustainable, significant weight loss. – Data from more than 18,000 participants demonstrates that Vida’s […]
Diabetes, Obesity Stigma Guidelines; Bariatric Surgery Up in Teens; Islet Cell Study
(MedPage Today) — In a new clinical guideline, the American College of Physicians recommends adding an SGLT2 inhibitor or GLP-1 receptor agonist to metformin and lifestyle modifications for adults with inadequately controlled type 2 diabetes…
Activation of AMPK by GLP-1R agonists mitigates Alzheimer-related phenotypes in transgenic mice
Nature Aging, Published online: 20 May 2025; doi:10.1038/s43587-025-00869-3 Zhang et al. identify GLP-1 receptor agonists mitigating Alzheimer’s disease-related cognitive decline and amyloid pathology in a transgenic mouse model via promoting phagocytosis and through activation of the CaMKK2–AMPK signaling pathway.
I Overdosed on Ozempic – Here’s What to Learn From My Mistake
Let’s start with the obvious: I didn’t mean to overdose on Ozempic, and I don’t recommend it. But I did. It was one part grief brain, one part “I’ve got this,” and about 2 milligrams of miscalculation. I’d been staring at that little pen in my fridge for months, a free sample from my doctor, […]