May 9
Journal Article – Real-world use of tirzepatide among individuals without evidence of type2 diabetes: Results from the Veradign® database
March 14, 2025 Hunter Gibble T, Chinthammit C, Ward JM, Cappell K, Sedgley R, Bonafede M, Liao B, Hankosky ER. Real-world use of tirzepatide among individuals without evidence of type 2 diabetes: Results from the Veradigm® database. Diabetes Obes Metab. 2025 Jun;27(6):3185-3194. doi: 10.1111/dom.16330. Epub 2025 Mar 14. PMID: 40084533; PMCID: PMC12046461. This source describes … Read more
Do Medicare, Medicaid cover weight loss drugs? It depends
Millions of Americans fighting obesity faced a setback last month when the Trump administration declined to allow Medicare and Medicaid to cover popular weight loss drugs like Wegovy and Zepbound. The Centers for Medicare & Medicaid Services (CMS) last month rejected a proposal from the Biden administration that would have required Medicare and Medicaid to … Read more
Currency hedging and new U.S. factories: Novo Nordisk CFO thinks Wegovy maker can outmaneuver global trade wars
Novo Nordisk is hedging and building its way around a global tariff war that may threaten the Wegovy maker’s plans to expand in the U.S. Karsten Munk Knudsen, Novo Nordisk’s chief financial officer, told Fortune the company is well-placed to handle the geopolitical upheaval that rocked global business in March and April. The dust has … Read more
GLP-1 Drugs Are a Big Success. Now for the Lawsuits
Barbara Pfeffer Billauer, ACSH We expected miracles; what we got was a legal minefield. As GLP-1 drugs like Ozempic reshape bodies and bottom lines, a growing swarm of lawsuits threatens to…
Former FDA Chief Praises ‘Revolutionary’ GLP-1s
“Revolutionary” anti-obesity drugs like Ozempic appear to be the right tool to deal with the addictive, highly processed foods that are ruining Americans’ health, former FDA Commissioner David Kessler writes at the New York Times . He says GLP-1 drugs helped him end the “cycle of despair” of weight loss and…
Mayo Clinic Study: Genetic Test Can Predict GLP-1 Nausea Side Effects
What You Should Know: – A new study from Mayo Clinic, released this past weekend, signals a significant advancement in understanding and potentially mitigating the challenging side effects associated with popular GLP-1 agonist medications like Wegovy and Zepbound. – Led by Mayo Clinic physician and obesity expert Andres Acosta, MD, PhD, the research reveals that … Read more
GIPR: Agonists and Antagonists Do the Same Thing, But How
For all the dramatic effects of the GLP-1 agonists (and now the GLP-1/GIPR ligands as a combination), there are still a lot of mysteries around how they work. Two new papers (published simultaneously) are helping to reveal some of what’s going on, and I very much suspect that we will have more surprises to uncover. … Read more
How just a fishing expedition helped lead to GLP-1
Professor of Medicine Joel Habener. Veasey Conway/Harvard Staff Photographer Health How just a fishing expedition helped lead to GLP-1 Story of game-changing therapy illustrates crucial role of fundamental research breakthroughs Jacob Sweet Harvard Staff Writer May 8, 2025 4 min read Part of the Profiles of Progress series Sometimes an important discovery springs from a … Read more