Could GLP1RA drugs lower high iron levels?
Increased iron levels can be dangerous for those with type 2 diabetes.
The five pillars of cancer care currently comprise surgery, radiotherapy, traditional chemotherapy, precision therapy, and immunotherapy. Each of these treatments addresses cancer in different ways, targeting the malignancy itself. However, the link between obesity and cancer has been well established, and obesity has been recognized as a risk factor for certain types of cancer. Given the strong correlation between obesity and cancer risk, including potential molecular mechanisms that may foster cancer growth, an emphasis on weight management could represent a profound shift in cancer prevention and treatment.
The integration of obesity management into the treatment paradigm could involve a multidisciplinary approach, incorporating dietary interventions, physical activity, behavioral changes, and potentially even novel pharmacological agents aimed at curbing weight gain. By addressing obesity as a modifiable risk factor, healthcare professionals may be able to not only treat cancer more effectively but also prevent it in certain instances. The introduction of weight management as another pillar in cancer care would require rigorous scientific research and clinical trials. However, if successfully implemented, it could revolutionize the way we approach cancer treatment and prevention, placing a strong emphasis on the patient’s overall well-being and lifestyle choices, and ushering in a new era of holistic cancer care.
It is the purpose of this website to draw attention to this unmet need in medicine and to address some of the questions that surround this new medical field.
Obesity is a major health concern that is not only associated with chronic diseases like cardiovascular disease, but it is also linked with an increased risk of cancer. According to the National Institutes of Health (NIH), 4-8% of all cancers can be attributed to obesity. The underlying mechanism of obesity causing cancer is complex, and researchers are still trying to gain a better understanding of it. However, researchers know that certain lifestyle changes can help reduce the risk of developing cancer due to obesity. In particular, diet, exercise, and behavior therapy are the mainstay of intervention to fight against obesity and, thereby, lower the risk of cancer. For more information, please click on the link to the research paper cited and also check out the NIH’s National Cancer Institute infographic on the cancers associated with overweight and obesity.
This webpage from the Centers for Disease Control and Prevention (CDC) explores the strong link between obesity and cancer risk. It outlines how being overweight or obese increases the likelihood of developing 13 specific types of cancer, which account for 40% of all cancer diagnoses in the United States. The article also discusses how excess weight can lead to bodily changes, such as inflammation and hormone imbalances, which contribute to cancer development. Finally, the CDC provides practical steps for individuals and healthcare providers to reduce the risk of obesity-related cancers, emphasizing the importance of healthy lifestyle choices and preventative measures.
The Link Between Obesity and Cancer provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions on cancers for which we have sufficient and new evidence of a causal relationship with obesity. Readers will gain fundamental knowledge about which different cancer types are related to obesity and why. The book provides a significant knowledge base for clinicians to know when to act, along with specific management guidelines for patients with obesity as well as how to understand the potential risk factors and how to directly or indirectly minimize these risks. The book also provides scientific data for any researcher in the field, identifying the molecular mechanisms and links behind the development of malignancy and promoting research on new affective target pathways m developing therapeutic strategies.
Key Features
• Provides essential knowledge on how to understand the link between obesity and cancer and why and how this occurs; enables readers to gain fundamental knowledge on which cancer types are related to obesity and why
• Provides a significent knowledge base for clinicians on when to act, along with patient management guidelines for patients with obesity as well as how to understand potential risk factors and how to minimize them
• Contains new scientific data and findings for researchers, which identify the molecular mechanisms and links behind the development of malignancy
The book, The Link Between Obesity and Cancer on sale at Amazon or at ScienceDirect®.
Increased iron levels can be dangerous for those with type 2 diabetes.
GLP1RA agonists have been increasing in popularity for treating obesity and type 2 diabetes.
The Senate Health, Education, Labor and Pension committee, led by Vermont Sen. Bernie Sanders, is hearing testimony from Novo Nordisk CEO Lars Fruergaard Jørgensen on the exhortative prices for their drugs in the U.S. CBS
Novo Nordisk (NVO) CEO Lars Fruergaard Jørgensen agreed today, during a Senate committee hearing, to sit down with lawmakers and pharmacy benefit managers (PBMs) to look into the possibility of cutting list prices for the
Novo Nordisk chief executive Lars Fruergaard Jørgensen faced questioning on Capitol Hill over the health care costs of the company’s weight-loss drugs Ozempic and Wegovy. NBC News’ Christine Romans reports on how Jørgensen claimed the
A retrospective analysis found an 8.8% cumulative risk for sarcoma following radiation therapy in carriers of TP53 pathogenic variant at 15 years. Medscape Medical News
The hearing is the latest move in Sanders’ crusade to pressure drugmakers to lower their prices.
Novo Nordisk (NVO) CEO Lars Fruergaard Jørgensen will shift the blame for the high prices of the company’s popular weight loss treatments to drug middlemen and the ‘complex’ U.S. health care system today during a
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